		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
amp_2q11.2	104 (20%)	407	6.8222e-12	4.62e-09	3.5471e-14	2.43e-11	0.49915	1	0.30966	1	0.050541	1	0.12464	1	0.064802	1	0.36131	1	0.14771	1	0.52098	1
amp_2q31.2	108 (21%)	403	5.0121e-15	3.47e-12	1.3241e-16	9.27e-14	0.2406	1	0.61531	1	0.18925	1	0.14526	1	0.19123	1	0.73591	1	0.33115	1	0.87246	1
amp_3q26.33	372 (73%)	139	1.0037e-18	7.09e-16	3.5192e-15	2.44e-12	0.12913	1	0.31697	1	2.2565e-07	0.000146	2.707e-05	0.0164	0.00016652	0.0986	0.41275	1	0.042467	1	0.16466	1
amp_5p15.33	231 (45%)	280	5.0094e-19	3.55e-16	2.3066e-06	0.00145	0.84692	1	0.4514	1	0.15501	1	0.17253	1	0.68666	1	1	1	0.96281	1	1	1
amp_5p12	203 (40%)	308	1.545e-15	1.08e-12	6.5065e-05	0.039	0.57448	1	0.06841	1	0.31094	1	0.43525	1	0.58108	1	0.70827	1	0.98896	1	0.95348	1
amp_6p12.1	107 (21%)	404	3.2283e-08	2.12e-05	1.3098e-05	0.00799	0.45033	1	0.78652	1	0.84719	1	0.62454	1	0.44848	1	0.042245	1	0.91701	1	0.35784	1
amp_6q12	92 (18%)	419	1.6332e-08	1.08e-05	0.0003278	0.189	0.27922	1	0.66663	1	0.85038	1	0.98306	1	0.30147	1	0.18831	1	0.79625	1	0.77466	1
amp_7p11.2	215 (42%)	296	1.0322e-12	7.04e-10	6.6557e-12	4.51e-09	0.994	1	0.18648	1	0.048628	1	0.060006	1	0.7163	1	0.16432	1	0.26276	1	0.37682	1
amp_7q21.3	164 (32%)	347	8.9136e-15	6.15e-12	1.6465e-15	1.15e-12	0.32932	1	1	1	0.30491	1	0.73498	1	0.084156	1	0.4309	1	0.28432	1	0.61889	1
amp_8p11.23	156 (31%)	355	2.5278e-06	0.00158	0.014242	1	0.80044	1	0.65375	1	0.12792	1	0.079898	1	0.0031904	1	0.021744	1	0.28695	1	0.12909	1
amp_8q11.21	305 (60%)	206	2.8541e-11	1.93e-08	1.3449e-07	8.74e-05	0.098277	1	0.42915	1	0.0015776	0.888	0.00020776	0.122	0.033645	1	0.00026699	0.155	0.048183	1	0.0015078	0.85
amp_8q24.21	379 (74%)	132	3.5914e-17	2.52e-14	2.1814e-10	1.46e-07	0.31014	1	0.46678	1	0.012742	1	7.2595e-05	0.0434	0.064552	1	0.0032991	1	0.001864	1	0.014988	1
amp_9p24.1	122 (24%)	389	3.7322e-21	2.68e-18	5.294e-06	0.00328	0.13613	1	0.12672	1	0.0028632	1	0.0020594	1	0.034856	1	0.59263	1	0.1599	1	0.48096	1
amp_9p23	121 (24%)	390	2.1665e-19	1.54e-16	1.3012e-05	0.00795	0.38513	1	0.40723	1	0.00335	1	0.0052965	1	0.059506	1	1	1	0.27121	1	0.62595	1
amp_9p13.3	135 (26%)	376	2.1913e-14	1.51e-11	0.0035093	1	0.47979	1	0.51719	1	0.00086011	0.493	0.0033147	1	0.0029691	1	0.037711	1	0.83421	1	0.2066	1
amp_9q34.3	174 (34%)	337	9.0513e-14	6.2e-11	0.0029803	1	0.23878	1	0.1484	1	0.94995	1	0.20853	1	0.70956	1	0.69927	1	0.91996	1	0.84691	1
amp_11p13	101 (20%)	410	0.00024258	0.142	0.0025986	1	0.45581	1	0.32128	1	0.95667	1	0.49803	1	0.80455	1	0.24562	1	0.31474	1	0.49532	1
amp_11q13.3	223 (44%)	288	1.8601e-26	1.35e-23	7.2606e-11	4.89e-08	0.82829	1	0.9272	1	0.17146	1	0.068681	1	0.41451	1	0.1394	1	0.24935	1	0.39352	1
amp_12p13.33	162 (32%)	349	2.8164e-17	1.98e-14	1.6848e-07	0.000109	0.042947	1	0.096592	1	0.0092718	1	0.010554	1	0.023356	1	0.76794	1	0.16854	1	0.82657	1
amp_12q15	101 (20%)	410	3.462e-07	0.000222	0.00038989	0.225	0.067753	1	0.60685	1	0.12642	1	0.093084	1	0.90727	1	0.90873	1	1	1	0.32698	1
amp_13q22.1	104 (20%)	407	1.9237e-13	1.31e-10	4.3598e-06	0.0027	0.14972	1	0.37382	1	0.32609	1	0.35612	1	0.43572	1	0.13696	1	0.82653	1	0.40805	1
amp_13q34	106 (21%)	405	1.3306e-09	8.84e-07	7.3945e-05	0.0441	0.25238	1	0.66114	1	0.19841	1	0.26769	1	0.34523	1	0.053041	1	0.334	1	0.16363	1
amp_15q26.3	102 (20%)	409	0.0019494	1	0.01535	1	0.45193	1	0.91557	1	0.61145	1	0.64665	1	0.33209	1	0.4893	1	0.68304	1	0.43919	1
amp_17q12	88 (17%)	423	1.9652e-08	1.29e-05	1.4554e-06	0.000915	0.18689	1	0.5439	1	0.010882	1	0.11493	1	0.010085	1	1	1	1	1	1	1
amp_18p11.31	152 (30%)	359	6.7675e-17	4.74e-14	2.1955e-09	1.46e-06	0.51924	1	0.81768	1	0.080561	1	4.2845e-05	0.0258	0.76272	1	0.27166	1	0.56727	1	0.23069	1
amp_18q11.2	101 (20%)	410	5.7754e-07	0.000367	0.00020776	0.122	0.51715	1	0.83009	1	0.36915	1	0.014094	1	0.038495	1	0.24888	1	0.81748	1	0.90421	1
amp_20p12.2	189 (37%)	322	2.7965e-05	0.0169	2.6657e-05	0.0162	0.87267	1	0.69874	1	0.088995	1	0.055905	1	0.14944	1	0.001265	0.715	0.022984	1	0.030948	1
amp_20q11.22	224 (44%)	287	4.7727e-08	3.12e-05	8.5397e-06	0.00525	0.49944	1	0.12579	1	0.10562	1	0.338	1	0.4755	1	0.012507	1	0.22936	1	0.024604	1
amp_xq28	145 (28%)	366	2.3239e-10	1.56e-07	3.9649e-06	0.00247	0.63529	1	0.26261	1	0.29789	1	0.2397	1	0.15557	1	0.065772	1	0.95451	1	0.69465	1
del_1p36.21	94 (18%)	417	3.0443e-10	2.03e-07	8.2629e-19	5.84e-16	0.00084556	0.486	0.60675	1	4.1946e-07	0.000268	5.5363e-05	0.0333	0.00086385	0.494	0.095303	1	0.04088	1	0.013476	1
del_1p13.2	127 (25%)	384	6.0511e-16	4.23e-13	5.5749e-15	3.86e-12	0.025627	1	0.37983	1	0.025781	1	0.041755	1	0.018017	1	0.91536	1	0.096666	1	0.012322	1
del_1q44	47 (9%)	464	0.00098551	0.563	0.0051785	1	0.71192	1	0.8285	1	0.013842	1	0.019465	1	0.00054949	0.317	0.037548	1	0.023738	1	0.40366	1
del_2q21.2	73 (14%)	438	0.81917	1	0.021595	1	0.70195	1	0.76963	1	0.025604	1	0.0017283	0.964	0.00025197	0.147	0.51139	1	0.066707	1	0.52431	1
del_2q22.1	114 (22%)	397	0.068414	1	1.9141e-05	0.0117	0.34958	1	0.8835	1	0.28281	1	0.13546	1	0.17565	1	0.44307	1	0.89357	1	0.44465	1
del_2q36.2	152 (30%)	359	4.3898e-08	2.87e-05	1.4639e-07	9.5e-05	0.091498	1	0.51364	1	0.010545	1	0.0032177	1	0.092178	1	0.4813	1	0.12932	1	0.078896	1
del_3p24.1	357 (70%)	154	2.1714e-31	1.58e-28	3.1847e-24	2.3e-21	0.41173	1	0.082634	1	0.0016304	0.916	0.010707	1	0.0079183	1	0.0050395	1	0.11141	1	0.058311	1
del_3p12.1	332 (65%)	179	1.627e-33	1.19e-30	1.3846e-24	1e-21	0.82719	1	0.34292	1	0.020849	1	0.060174	1	0.076238	1	0.068083	1	0.34091	1	0.67868	1
del_4p15.2	201 (39%)	310	1.3878e-17	9.77e-15	3.452e-15	2.4e-12	0.011563	1	0.78197	1	9.527e-05	0.0567	7.1155e-05	0.0426	0.053163	1	1	1	0.0038185	1	0.019056	1
del_4q22.1	164 (32%)	347	5.6737e-15	3.92e-12	1.9774e-10	1.33e-07	0.24817	1	0.40341	1	0.0087779	1	0.0069821	1	0.208	1	0.376	1	0.47365	1	0.14694	1
del_4q35.2	206 (40%)	305	1.0546e-11	7.13e-09	1.2729e-05	0.00779	0.83958	1	0.00024641	0.144	0.012151	1	0.044163	1	0.32534	1	0.050146	1	0.40744	1	0.10986	1
del_5q11.2	209 (41%)	302	9.4851e-31	6.91e-28	2.4654e-22	1.78e-19	0.13206	1	0.17659	1	0.10115	1	0.0012478	0.706	0.18444	1	0.22489	1	0.3843	1	0.48153	1
del_5q15	219 (43%)	292	3.0141e-29	2.19e-26	6.1352e-21	4.39e-18	0.14324	1	0.65365	1	0.10937	1	0.0024773	1	0.23384	1	0.26715	1	0.62495	1	0.8062	1
del_5q35.3	195 (38%)	316	8.8197e-25	6.39e-22	6.4712e-21	4.63e-18	0.23762	1	0.02752	1	0.01935	1	0.00027952	0.162	0.33522	1	0.18693	1	0.45698	1	0.32872	1
del_6p25.3	93 (18%)	418	0.00028907	0.167	9.8519e-06	0.00605	0.044011	1	0.57385	1	0.0022871	1	0.1353	1	0.19465	1	0.81309	1	0.67658	1	0.3238	1
del_7q31.1	74 (14%)	437	0.0064342	1	0.28349	1	0.57268	1	0.83498	1	0.52088	1	0.48277	1	0.87673	1	1	1	0.57779	1	0.46008	1
del_7q36.1	127 (25%)	384	0.00010371	0.0615	0.44497	1	0.044908	1	0.92634	1	0.76747	1	0.9248	1	0.62887	1	0.91536	1	0.74988	1	0.41651	1
del_8p23.2	294 (58%)	217	1.4375e-21	1.03e-18	1.2559e-12	8.55e-10	0.28165	1	0.12161	1	0.0011926	0.676	1.2641e-05	0.00775	0.0020242	1	0.0022051	1	0.00021778	0.128	6.197e-05	0.0372
del_9p23	233 (46%)	278	1.9898e-28	1.44e-25	1.4765e-19	1.05e-16	0.28096	1	0.08739	1	0.82309	1	0.87601	1	0.76181	1	1	1	0.25439	1	0.92832	1
del_9p21.3	292 (57%)	219	4.7906e-18	3.38e-15	9.1592e-20	6.51e-17	0.66249	1	0.088644	1	0.14447	1	0.18056	1	1	1	0.35417	1	0.10795	1	0.015212	1
del_9q21.11	103 (20%)	408	1.4025e-13	9.59e-11	2.2508e-07	0.000145	0.96951	1	0.54095	1	0.85172	1	0.92442	1	0.72515	1	0.30171	1	0.48387	1	0.12151	1
del_9q34.3	76 (15%)	435	5.3929e-07	0.000344	0.0010759	0.612	0.60565	1	0.2732	1	0.44555	1	0.58767	1	0.71556	1	0.89833	1	0.19588	1	0.39974	1
del_10p15.3	165 (32%)	346	7.6955e-07	0.000488	8.4258e-07	0.000533	0.60139	1	0.33923	1	0.12632	1	0.12792	1	0.14522	1	0.06185	1	0.099726	1	0.33737	1
del_10p11.21	152 (30%)	359	2.3397e-08	1.54e-05	2.2865e-07	0.000147	0.45344	1	0.064173	1	0.27652	1	0.57075	1	0.017591	1	0.48203	1	0.13242	1	0.7912	1
del_10q23.31	134 (26%)	377	6.9727e-06	0.0043	1.3692e-06	0.000863	0.1339	1	0.8654	1	7.4193e-05	0.0442	0.0016884	0.944	0.0074511	1	0.53148	1	0.043975	1	0.51115	1
del_11p15.5	156 (31%)	355	7.6422e-11	5.14e-08	2.5171e-10	1.68e-07	0.86069	1	0.54759	1	3.7618e-05	0.0227	0.00020721	0.122	2.0949e-07	0.000136	0.11159	1	0.16131	1	0.0095294	1
del_11q23.1	239 (47%)	272	2.1566e-06	0.00135	2.4465e-15	1.7e-12	0.087819	1	0.042172	1	3.0852e-05	0.0187	4.2202e-06	0.00262	0.0019633	1	0.19881	1	0.022829	1	0.10873	1
del_12q24.33	60 (12%)	451	3.6049e-06	0.00225	0.00016935	0.1	0.61174	1	0.71815	1	0.85129	1	0.68632	1	0.49159	1	0.56237	1	0.059461	1	0.34181	1
del_13q12.11	224 (44%)	287	8.601e-21	6.14e-18	4.0633e-12	2.76e-09	0.1476	1	0.67692	1	0.024576	1	0.0016602	0.93	0.82625	1	0.71169	1	0.59171	1	0.088158	1
del_13q14.2	209 (41%)	302	2.1636e-14	1.49e-11	1.2042e-09	8.02e-07	0.10927	1	0.8245	1	5.4386e-06	0.00336	1.1736e-08	7.75e-06	0.0035031	1	0.30497	1	0.19621	1	0.0097128	1
del_14q11.2	72 (14%)	439	0.0035522	1	0.019699	1	0.3138	1	0.71254	1	0.11365	1	0.32397	1	0.036833	1	0.022371	1	0.15794	1	0.078116	1
del_14q32.32	73 (14%)	438	0.0002556	0.149	2.8083e-12	1.91e-09	0.019079	1	0.14962	1	8.8947e-07	0.000561	1.0159e-07	6.61e-05	0.0032818	1	0.018252	1	0.019478	1	0.0026584	1
del_15q15.1	119 (23%)	392	7.5278e-09	4.98e-06	0.21931	1	0.668	1	0.24331	1	0.071014	1	0.013947	1	0.79968	1	0.51616	1	0.68963	1	0.53527	1
del_16q23.3	102 (20%)	409	0.0011773	0.669	4.6253e-07	0.000296	0.16003	1	0.068121	1	4.0043e-06	0.00249	2.3722e-07	0.000153	0.0040432	1	0.050558	1	0.0060045	1	0.016452	1
del_17q25.3	68 (13%)	443	0.039053	1	0.00023331	0.137	0.42568	1	0.092978	1	0.01238	1	0.0016536	0.928	0.003749	1	0.03024	1	0.0048932	1	0.060463	1
del_18q21.2	259 (51%)	252	2.4445e-20	1.74e-17	1.2995e-20	9.27e-18	0.89438	1	0.11744	1	0.0066898	1	0.0083092	1	0.018628	1	0.0024592	1	0.19245	1	0.095287	1
del_18q23	278 (54%)	233	6.4219e-23	4.63e-20	4.703e-22	3.38e-19	0.25472	1	0.0082623	1	0.0051287	1	0.0030921	1	0.024253	1	0.0043499	1	0.075053	1	0.1797	1
del_19p13.3	165 (32%)	346	6.7636e-08	4.41e-05	7.2885e-07	0.000463	0.4428	1	0.49852	1	0.020068	1	0.24711	1	0.22063	1	0.010499	1	0.53689	1	0.36731	1
del_19q13.43	94 (18%)	417	7.7352e-07	0.00049	5.6651e-07	0.000361	0.32665	1	1	1	0.86469	1	0.65371	1	0.6209	1	0.40705	1	0.60212	1	0.78132	1
del_21q22.3	195 (38%)	316	9.4932e-15	6.54e-12	2.6474e-10	1.77e-07	0.60914	1	0.33362	1	0.045595	1	0.14336	1	0.61086	1	0.073033	1	0.91387	1	0.2699	1
del_22q13.31	84 (16%)	427	0.0010131	0.577	0.0094807	1	0.68418	1	0.94806	1	0.019696	1	0.8441	1	0.011616	1	0.31928	1	0.13017	1	0.7256	1
del_xp22.2	152 (30%)	359	3.9347e-08	2.58e-05	1.2684e-09	8.43e-07	0.31595	1	0.16271	1	0.087114	1	0.24225	1	0.017572	1	0.54647	1	0.38769	1	0.86809	1
del_xp21.3	154 (30%)	357	6.1224e-09	4.05e-06	2.7389e-06	0.00171	0.55614	1	0.60705	1	0.46883	1	0.10632	1	0.21039	1	0.42232	1	0.73841	1	0.86531	1
del_xq21.33	74 (14%)	437	6.159e-06	0.0038	3.5159e-07	0.000225	0.48692	1	0.23732	1	0.0008579	0.492	0.0061436	1	9.5749e-05	0.0569	0.035999	1	0.22181	1	0.012552	1
