		Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q
amp_1p22.3	48 (24%)	151	0.0002063	0.0844	0.002807	1	0.00011841	0.0493	0.0043119	1	0.21691	1	0.91094	1	0.065478	1	1	1
amp_1q22	145 (73%)	54	1.823e-06	0.000797	6.7694e-08	2.98e-05	0.0041159	1	0.031879	1	0.060209	1	0.018681	1	0.2456	1	0.10968	1
amp_1q42.3	139 (70%)	60	0.00029586	0.12	0.00021618	0.0881	0.0043476	1	0.056038	1	0.30829	1	0.14033	1	0.41258	1	0.74554	1
amp_2p24.1	44 (22%)	155	0.0056751	1	0.61995	1	0.45627	1	0.53782	1	0.41612	1	0.75719	1	0.20468	1	0.91599	1
amp_2q31.2	39 (20%)	160	0.021758	1	0.95051	1	0.55899	1	0.82301	1	0.0198	1	0.11212	1	0.55122	1	0.61793	1
amp_3q26.31	42 (21%)	157	0.00021603	0.0881	0.074952	1	0.58777	1	0.17164	1	0.00051639	0.206	0.018065	1	0.036057	1	0.049957	1
amp_4q13.3	17 (9%)	182	0.22509	1	0.55552	1	0.35869	1	0.57274	1	1	1	0.65028	1	0.64807	1	0.78448	1
amp_5p15.33	92 (46%)	107	4.5018e-06	0.00196	0.059904	1	0.078998	1	0.23528	1	0.38875	1	0.32658	1	0.093384	1	0.51027	1
amp_5q35.3	65 (33%)	134	2.9105e-05	0.0125	0.029716	1	0.66414	1	0.71617	1	1	1	0.94817	1	0.25677	1	0.74406	1
amp_6p25.2	87 (44%)	112	6.8881e-09	3.06e-06	0.00017288	0.0711	8.649e-05	0.0364	0.012155	1	0.41968	1	0.82284	1	0.54739	1	1	1
amp_6p21.1	87 (44%)	112	6.8881e-09	3.06e-06	5.6176e-06	0.00244	0.00083656	0.329	0.0084999	1	0.32628	1	0.52786	1	0.35859	1	0.67359	1
amp_6q12	63 (32%)	136	1.6497e-07	7.24e-05	0.024269	1	0.0054219	1	0.063132	1	0.19198	1	0.8706	1	0.51399	1	0.90599	1
amp_6q12	46 (23%)	153	0.00013117	0.0544	0.0067877	1	0.0041278	1	0.057897	1	0.48266	1	0.96325	1	0.18053	1	0.54536	1
amp_7q21.2	70 (35%)	129	0.24064	1	0.20556	1	0.36788	1	0.28319	1	0.21388	1	0.55635	1	0.49392	1	0.35191	1
amp_7q31.2	68 (34%)	131	0.36451	1	0.21541	1	0.35084	1	0.56364	1	0.15421	1	0.40907	1	0.46929	1	0.40008	1
amp_8q11.1	79 (40%)	120	1.7523e-10	7.8e-08	0.73383	1	0.12568	1	0.0013605	0.529	0.66105	1	0.25691	1	0.37079	1	0.16466	1
amp_8q24.21	119 (60%)	80	3.424e-13	1.53e-10	0.060436	1	0.083366	1	6.1922e-05	0.0263	0.14485	1	0.51684	1	0.58205	1	0.70871	1
amp_9q34.2	29 (15%)	170	0.14429	1	0.59279	1	0.057602	1	0.12974	1	0.19199	1	0.61007	1	0.17393	1	0.70998	1
amp_10p15.1	41 (21%)	158	0.52287	1	0.042611	1	0.21274	1	0.053262	1	0.14451	1	0.79484	1	0.32305	1	0.38822	1
amp_11q13.3	38 (19%)	161	0.40013	1	0.71319	1	0.068802	1	0.4997	1	0.1015	1	0.30994	1	0.084007	1	0.74037	1
amp_13q32.3	37 (19%)	162	6.8994e-05	0.0292	0.014103	1	0.0012494	0.487	0.025968	1	0.38686	1	0.5863	1	0.015936	1	0.25666	1
amp_15q26.3	32 (16%)	167	0.0075513	1	0.21764	1	0.37437	1	0.14229	1	0.38981	1	0.31844	1	0.17556	1	0.085618	1
amp_16q12.1	20 (10%)	179	0.59661	1	0.91895	1	0.12793	1	0.59349	1	0.83463	1	0.447	1	0.30999	1	0.47719	1
amp_17p11.2	30 (15%)	169	0.031973	1	0.11043	1	0.64256	1	0.27542	1	0.78453	1	0.89685	1	0.40043	1	0.69694	1
amp_17q25.3	86 (43%)	113	0.00016641	0.0687	0.0026908	1	0.066606	1	0.092907	1	0.17615	1	0.18834	1	0.11583	1	0.24535	1
amp_19q13.11	54 (27%)	145	0.10975	1	0.00044027	0.176	0.00030955	0.124	0.00030062	0.121	0.25181	1	0.0041097	1	0.0015196	0.588	0.004049	1
amp_20q13.33	69 (35%)	130	0.00065055	0.256	0.021449	1	2.1039e-05	0.00905	0.0072443	1	0.21839	1	0.22263	1	0.0049237	1	0.083133	1
amp_xq28	48 (24%)	151	9.2052e-05	0.0387	0.026251	1	0.13628	1	0.31665	1	0.071696	1	0.00884	1	0.15679	1	0.089018	1
del_1p36.23	93 (47%)	106	0.00027225	0.11	1.4495e-05	0.00625	7.9994e-05	0.0338	0.015547	1	0.60233	1	0.090244	1	0.011178	1	0.10147	1
del_2q22.1	25 (13%)	174	0.019453	1	0.9671	1	0.49989	1	0.8824	1	0.0065304	1	0.37532	1	0.95333	1	0.38173	1
del_2q37.3	42 (21%)	157	0.0083358	1	0.86951	1	0.0057727	1	0.01794	1	0.00019476	0.0799	0.053311	1	0.25293	1	0.27919	1
del_3p13	42 (21%)	157	0.060063	1	0.095554	1	0.0053081	1	0.00011243	0.0469	0.1003	1	0.084659	1	4.0156e-05	0.0171	0.0027034	1
del_4p16.3	44 (22%)	155	0.0031489	1	0.0057218	1	0.064263	1	0.13642	1	0.74326	1	0.34397	1	0.83166	1	0.29624	1
del_4q24	93 (47%)	106	6.0116e-08	2.65e-05	0.0067303	1	0.0019758	0.759	0.02292	1	0.2622	1	0.66885	1	0.4128	1	0.61437	1
del_4q34.3	85 (43%)	114	3.1633e-07	0.000139	0.00016692	0.0688	0.0011091	0.435	0.045759	1	0.86598	1	0.26922	1	0.2688	1	0.26258	1
del_6q16.3	69 (35%)	130	0.086864	1	0.49143	1	0.18041	1	0.42075	1	0.52798	1	0.50152	1	0.79172	1	0.9424	1
del_6q27	72 (36%)	127	0.0069972	1	0.3966	1	0.40674	1	0.41012	1	0.86458	1	0.040385	1	0.50145	1	0.2314	1
del_8p23.2	128 (64%)	71	1.6109e-11	7.2e-09	0.0081841	1	0.020109	1	0.44118	1	0.85505	1	0.52932	1	0.77968	1	0.49499	1
del_9p21.3	80 (40%)	119	2.9273e-05	0.0125	0.20043	1	0.11743	1	0.3935	1	0.22501	1	0.15819	1	0.2072	1	0.088905	1
del_9q34.2	64 (32%)	135	0.0080888	1	0.10077	1	0.0098159	1	0.0088262	1	0.39246	1	0.37019	1	0.53056	1	0.28493	1
del_10q23.31	60 (30%)	139	0.011904	1	0.3017	1	3.2505e-06	0.00142	0.0040609	1	0.094717	1	0.021465	1	0.00042238	0.169	0.11981	1
del_10q24.33	61 (31%)	138	0.030436	1	0.80666	1	4.7008e-05	0.02	0.0037848	1	0.088938	1	0.030423	1	0.0020271	0.776	0.21227	1
del_11q14.1	44 (22%)	155	0.093954	1	0.19066	1	0.3537	1	0.33837	1	0.60904	1	0.92065	1	0.52174	1	0.68952	1
del_11q23.3	51 (26%)	148	0.037888	1	0.0098662	1	0.37546	1	0.47887	1	0.56105	1	0.88314	1	0.14446	1	0.77456	1
del_12p12.1	46 (23%)	153	0.3688	1	0.11139	1	0.0014378	0.558	0.3707	1	0.025185	1	0.046723	1	0.034504	1	0.0025734	0.983
del_12q24.33	36 (18%)	163	0.012863	1	0.18853	1	0.60668	1	0.64227	1	0.88825	1	0.8431	1	0.51313	1	0.59657	1
del_13q12.11	67 (34%)	132	9.6681e-05	0.0404	0.069008	1	0.030727	1	0.0064799	1	0.93965	1	0.18056	1	0.044406	1	0.07703	1
del_13q14.2	94 (47%)	105	5.307e-11	2.37e-08	0.084636	1	0.0017376	0.671	9.2258e-05	0.0387	0.2622	1	0.13296	1	0.00021894	0.0889	0.046623	1
del_13q22.2	74 (37%)	125	1.3061e-08	5.77e-06	0.099397	1	0.050633	1	0.00059041	0.234	0.44484	1	0.43388	1	0.00061465	0.243	0.23276	1
del_14q23.3	69 (35%)	130	0.0056781	1	0.5502	1	0.0080047	1	0.28599	1	0.35262	1	0.015128	1	0.0097394	1	0.027441	1
del_14q32.33	70 (35%)	129	5.4563e-05	0.0232	0.29023	1	0.064153	1	0.18052	1	0.11766	1	0.063603	1	0.041125	1	0.13006	1
del_16q23.1	83 (42%)	116	6.5782e-06	0.00285	0.0005224	0.207	8.8432e-06	0.00382	0.0011258	0.44	0.62794	1	0.041276	1	0.037119	1	0.093084	1
del_17p11.2	111 (56%)	88	0.0054308	1	0.11496	1	0.0056039	1	0.066649	1	0.00015127	0.0626	0.0025913	0.987	0.0044344	1	0.001832	0.705
del_19p13.3	46 (23%)	153	0.00037552	0.151	0.06453	1	0.01666	1	0.036888	1	0.3314	1	0.11567	1	0.33434	1	0.21401	1
del_20p12.1	14 (7%)	185	0.32853	1	0.49147	1	0.41838	1	0.81213	1	0.59294	1	0.63908	1	0.66196	1	0.38651	1
del_22q13.32	59 (30%)	140	0.60604	1	0.89024	1	0.0244	1	0.063597	1	0.63976	1	0.74543	1	0.50705	1	0.59884	1
