		Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	8 (9%)	83	0.5564	1	0.1624	1	0.59393	1	0.31098	1	0.45684	1	0.40389	1	0.26535	1	0.52503	1
1q gain	24 (26%)	67	0.0075164	1	0.025413	1	0.45234	1	0.068132	1	0.36212	1	0.28235	1	0.052693	1	0.16869	1
2p gain	6 (7%)	85	0.13638	1	0.083777	1	0.18561	1	0.012648	1	0.62769	1	0.41016	1	0.66167	1	0.19186	1
2q gain	7 (8%)	84	0.4479	1	0.36604	1	0.59393	1	0.0071886	1	0.74417	1	0.8816	1	1	1	0.52503	1
3p gain	5 (5%)	86	0.13335	1	0.066774	1	0.70692	1	0.66713	1	0.086453	1	1	1	0.43303	1	1	1
3q gain	10 (11%)	81	0.014126	1	0.011646	1	0.42273	1	0.19132	1	0.81705	1	0.33612	1	0.69123	1	0.31355	1
5p gain	12 (13%)	79	0.0053242	1	0.039013	1	0.43673	1	0.31025	1	0.7689	1	1	1	0.33978	1	0.67099	1
5q gain	8 (9%)	83	0.12046	1	0.1624	1	0.56343	1	0.73203	1	0.8432	1	0.89544	1	1	1	1	1
7p gain	25 (27%)	66	0.0029538	1	0.00055016	0.295	0.036877	1	0.00077234	0.412	0.03395	1	0.010229	1	0.016922	1	0.0028533	1
7q gain	22 (24%)	69	0.0033248	1	0.0038968	1	0.13838	1	0.0044931	1	0.13148	1	0.023468	1	0.040622	1	0.018204	1
8p gain	13 (14%)	78	0.0058598	1	0.039013	1	0.78249	1	0.051019	1	0.7689	1	0.47341	1	0.72056	1	0.43966	1
8q gain	24 (26%)	67	0.0018499	0.967	0.0010977	0.581	0.22788	1	0.0014122	0.743	0.26049	1	0.18098	1	0.039771	1	0.040548	1
9p gain	3 (3%)	88	0.069095	1	0.36125	1	0.60203	1	0.31483	1	0.57803	1	0.30453	1	0.45603	1	0.32362	1
9q gain	3 (3%)	88	0.069095	1	0.36125	1	0.60203	1	0.31483	1	0.57803	1	0.30453	1	0.45603	1	0.32362	1
10p gain	4 (4%)	87	0.055748	1	0.18169	1	0.32245	1	0.31483	1	0.26186	1	1	1	0.59621	1	0.32362	1
10q gain	6 (7%)	85	0.016557	1	0.022997	1	0.18331	1	0.32537	1	0.13191	1	0.53201	1	0.34489	1	0.14528	1
11p gain	9 (10%)	82	0.011518	1	0.015649	1	0.43392	1	0.52928	1	0.44951	1	0.65697	1	0.81787	1	0.38944	1
11q gain	7 (8%)	84	0.077772	1	0.32342	1	0.77423	1	0.31098	1	0.77902	1	0.8816	1	0.88821	1	0.52503	1
12p gain	10 (11%)	81	1.4577e-06	0.000819	0.013014	1	0.73269	1	0.025723	1	0.75361	1	0.30898	1	0.47332	1	0.16006	1
12q gain	7 (8%)	84	0.00021803	0.12	0.053647	1	0.30326	1	0.1219	1	0.62753	1	0.46309	1	0.52314	1	0.26591	1
13q gain	9 (10%)	82	1	1	0.45596	1	0.34682	1	0.51488	1	0.17769	1	0.053528	1	0.4472	1	0.40035	1
14q gain	10 (11%)	81	0.014126	1	0.33468	1	0.75699	1	0.76799	1	0.079565	1	0.91085	1	0.63061	1	1	1
15q gain	7 (8%)	84	0.50776	1	0.37473	1	0.46877	1	0.44591	1	0.88428	1	0.48777	1	0.075067	1	0.4124	1
16p gain	10 (11%)	81	0.00015431	0.0853	0.0047575	1	0.3847	1	0.19132	1	0.46231	1	0.12003	1	0.25223	1	0.055384	1
16q gain	11 (12%)	80	0.00022743	0.125	0.002215	1	0.45047	1	0.1047	1	0.036243	1	0.19086	1	0.14927	1	0.025154	1
17q gain	4 (4%)	87	0.055748	1	0.13146	1	0.45706	1	0.32537	1	0.6241	1	0.10394	1	0.68175	1	0.14528	1
18p gain	13 (14%)	78	0.00048971	0.265	0.00019093	0.105	0.037176	1	0.0047224	1	0.11404	1	0.0014005	0.739	0.0019382	1	0.0021151	1
18q gain	4 (4%)	87	0.055748	1	0.36125	1	0.60203	1	0.31483	1	0.86401	1	0.30453	1	0.79541	1	0.32362	1
19p gain	4 (4%)	87	0.3426	1	0.67389	1	0.80596	1	1	1	0.29925	1	0.53201	1	0.34489	1	0.56412	1
19q gain	12 (13%)	79	0.058073	1	0.18825	1	0.3371	1	0.58927	1	0.3044	1	0.51586	1	0.14137	1	0.43966	1
20p gain	15 (16%)	76	0.0014081	0.742	0.011394	1	0.092011	1	0.10176	1	0.91128	1	0.26158	1	0.70078	1	0.12143	1
20q gain	20 (22%)	71	9.8449e-06	0.00548	0.046621	1	0.22258	1	0.074807	1	0.69806	1	0.27677	1	0.31997	1	0.1315	1
22q gain	6 (7%)	85	0.13638	1	0.0048332	1	0.30358	1	0.20221	1	0.85834	1	0.2734	1	0.84814	1	0.36858	1
xq gain	3 (3%)	88	1	1	1	1	0.081063	1	0.56859	1	0.66392	1	0.092565	1	0.45603	1	0.091096	1
1p loss	15 (16%)	76	0.014702	1	0.00047228	0.256	0.050144	1	0.0069076	1	0.62409	1	0.082652	1	0.11285	1	0.3162	1
1q loss	4 (4%)	87	0.3426	1	0.06152	1	0.7985	1	0.31483	1	1	1	0.59227	1	0.15752	1	0.79262	1
2p loss	7 (8%)	84	0.038566	1	0.12177	1	0.59393	1	0.73133	1	0.68394	1	0.40389	1	0.88821	1	0.52503	1
2q loss	3 (3%)	88	0.069095	1	0.36125	1	0.32245	1	0.31483	1	0.86401	1	0.30453	1	0.79541	1	0.32362	1
3p loss	14 (15%)	77	0.0048723	1	0.097821	1	0.85696	1	0.4533	1	0.8058	1	0.54025	1	0.20558	1	0.16415	1
3q loss	10 (11%)	81	0.14414	1	0.12379	1	0.73269	1	0.52928	1	0.64345	1	0.90094	1	0.13936	1	0.4786	1
4p loss	12 (13%)	79	0.10088	1	0.049709	1	0.079348	1	0.30199	1	0.20372	1	0.48776	1	0.4589	1	0.14793	1
4q loss	11 (12%)	80	0.18381	1	0.0042921	1	0.04115	1	0.39025	1	0.20514	1	0.46103	1	0.5706	1	0.049628	1
5p loss	4 (4%)	87	0.055748	1	0.18169	1	0.18331	1	0.32537	1	0.13191	1	0.10394	1	0.14191	1	0.14528	1
5q loss	8 (9%)	83	0.00036857	0.2	0.024195	1	0.081754	1	0.060182	1	0.49461	1	0.038075	1	0.0044853	1	0.044187	1
6p loss	32 (35%)	59	0.00075374	0.402	7.943e-05	0.0442	0.30156	1	0.00030331	0.165	0.16401	1	0.17801	1	0.013735	1	0.011827	1
6q loss	41 (45%)	50	8.127e-06	0.00454	3.8725e-07	0.000219	0.002169	1	8.1485e-07	0.00046	0.0045229	1	0.0010598	0.562	0.00056192	0.301	0.00051861	0.28
8p loss	13 (14%)	78	0.28102	1	0.029685	1	0.011932	1	0.051019	1	0.16255	1	0.015533	1	0.040751	1	0.0046319	1
8q loss	3 (3%)	88	0.19632	1	0.18403	1	0.32245	1	0.31483	1	0.57803	1	1	1	0.79541	1	0.60079	1
9p loss	36 (40%)	55	0.0031066	1	0.023489	1	0.034529	1	0.55294	1	0.23543	1	0.10208	1	0.032431	1	0.14245	1
9q loss	24 (26%)	67	0.081625	1	0.27381	1	0.72311	1	1	1	0.23838	1	0.7833	1	0.18695	1	0.68142	1
10p loss	15 (16%)	76	0.0027876	1	0.085514	1	0.49496	1	0.029265	1	0.44608	1	0.042997	1	0.077472	1	0.22376	1
10q loss	15 (16%)	76	0.00015416	0.0853	0.067614	1	0.48329	1	0.011224	1	0.80447	1	0.0081692	1	0.19815	1	0.10034	1
11p loss	8 (9%)	83	0.027845	1	0.65622	1	0.19897	1	1	1	0.074508	1	0.35481	1	0.093158	1	0.2299	1
11q loss	10 (11%)	81	0.14414	1	0.63933	1	0.48668	1	1	1	1	1	1	1	0.47332	1	1	1
12p loss	10 (11%)	81	0.011714	1	0.011646	1	0.026615	1	0.025723	1	0.047841	1	0.078204	1	0.47332	1	0.01335	1
12q loss	13 (14%)	78	0.00027517	0.151	0.002044	1	0.64264	1	0.1047	1	0.74804	1	0.061889	1	0.41812	1	0.16504	1
13q loss	11 (12%)	80	0.00028202	0.154	0.30829	1	0.062798	1	0.19132	1	0.30111	1	0.056363	1	0.30887	1	0.070749	1
14q loss	7 (8%)	84	0.88315	1	0.0074978	1	0.22657	1	0.73133	1	0.4192	1	0.52259	1	0.31302	1	0.11275	1
15q loss	15 (16%)	76	0.0002509	0.137	0.0001455	0.0806	0.022754	1	0.00055899	0.3	0.0015353	0.806	0.0053389	1	0.062117	1	8.7795e-05	0.0487
16p loss	3 (3%)	88	0.027608	1	0.36125	1	0.7985	1	0.31483	1	0.26186	1	1	1	0.31604	1	0.32362	1
16q loss	3 (3%)	88	0.1168	1	0.18403	1	0.32245	1	0.31483	1	0.86401	1	0.30453	1	0.31604	1	0.32362	1
17p loss	37 (41%)	54	1.3811e-11	7.84e-09	4.2634e-11	2.42e-08	0.00053021	0.285	4.2153e-06	0.00236	9.1967e-07	0.000519	0.0005163	0.279	1.1951e-06	0.000673	8.9579e-06	0.005
17q loss	12 (13%)	79	0.00095992	0.51	0.039013	1	0.61726	1	0.39025	1	0.46231	1	0.62597	1	0.27839	1	0.51948	1
18p loss	32 (35%)	59	0.80642	1	0.099298	1	0.23339	1	0.68011	1	0.35882	1	0.080111	1	0.31131	1	0.38672	1
18q loss	52 (57%)	39	0.0048095	1	0.0016043	0.841	0.39882	1	0.10374	1	0.036203	1	0.76078	1	0.09675	1	0.24153	1
19p loss	11 (12%)	80	0.00089086	0.474	0.079279	1	0.034301	1	0.0094224	1	0.47923	1	0.061889	1	0.21406	1	0.38269	1
19q loss	6 (7%)	85	0.10705	1	0.567	1	0.041815	1	0.14506	1	0.26703	1	0.014677	1	0.47269	1	0.10595	1
20p loss	9 (10%)	82	0.024908	1	0.078582	1	0.16429	1	0.31948	1	0.023685	1	0.39859	1	0.035048	1	0.27382	1
21q loss	32 (35%)	59	2.4365e-06	0.00137	0.0049596	1	0.019355	1	0.0055685	1	0.032318	1	0.087431	1	0.020657	1	0.10529	1
22q loss	20 (22%)	71	0.005673	1	0.022331	1	0.13387	1	0.12408	1	0.0803	1	0.22818	1	0.068642	1	0.34724	1
xq loss	9 (10%)	82	0.0003569	0.194	0.19333	1	0.26942	1	0.73203	1	0.090935	1	0.31628	1	0.070137	1	0.27382	1
