		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
amp_1p36.22	48 (14%)	303	1.0128e-09	7.12e-07	0.010786	1	0.50624	1	0.11804	1	0.00023677	0.12	0.099092	1	0.33927	1	0.050512	1	0.25769	1	0.037532	1
amp_1q21.3	129 (37%)	222	1.3172e-25	1.02e-22	6.2718e-10	4.42e-07	0.033926	1	0.013076	1	1.1217e-12	8.19e-10	1.2336e-07	8.14e-05	7.7596e-12	5.6e-09	6.5632e-07	0.000425	3.07e-07	2e-04	5.7545e-08	3.84e-05
amp_1q42.3	117 (33%)	234	1.807e-16	1.37e-13	2.7289e-05	0.0156	0.3983	1	0.73607	1	3.4133e-08	2.31e-05	9.183e-05	0.0495	9.7512e-09	6.71e-06	1.2548e-07	8.27e-05	0.0010938	0.482	1.597e-07	0.000105
amp_3q27.1	123 (35%)	228	1.0569e-07	7e-05	0.00086535	0.391	0.94951	1	0.092575	1	0.31542	1	0.85191	1	0.25572	1	0.011125	1	0.25205	1	0.0050018	1
amp_5p15.33	98 (28%)	253	7.9635e-21	6.12e-18	4.5081e-09	3.13e-06	0.13163	1	0.39617	1	4.1348e-10	2.92e-07	3.5587e-06	0.00222	6.1704e-06	0.00377	6.6272e-07	0.000428	0.0001619	0.0834	1.3721e-08	9.4e-06
amp_5p13.1	98 (28%)	253	7.9635e-21	6.12e-18	3.0769e-06	0.00193	0.71636	1	0.92344	1	8.7506e-09	6.05e-06	3.8997e-05	0.022	1.8012e-05	0.0105	3.4962e-06	0.00219	0.0042151	1	2.1638e-06	0.00137
amp_6p21.1	95 (27%)	256	2.0286e-19	1.55e-16	1.5382e-12	1.12e-09	0.33826	1	0.22823	1	0.00038722	0.186	0.00060659	0.28	0.00010586	0.056	5.2029e-05	0.029	0.0022533	0.94	1.4719e-06	0.000936
amp_6q12	69 (20%)	282	9.9453e-13	7.27e-10	5.3285e-07	0.000346	0.065636	1	0.28282	1	2.2052e-05	0.0127	4.2899e-05	0.0242	0.00022552	0.114	7.8432e-05	0.0427	0.0027926	1	4.5975e-05	0.0258
amp_6q21	64 (18%)	287	1.0066e-07	6.67e-05	0.0013971	0.608	0.3688	1	0.89862	1	0.00057824	0.268	2.6632e-05	0.0153	0.0027928	1	0.0025653	1	0.0019947	0.848	0.00031025	0.152
amp_7p22.1	180 (51%)	171	5.4875e-16	4.15e-13	6.3599e-06	0.00387	0.62712	1	0.89037	1	0.00019173	0.0976	0.0074877	1	0.051846	1	0.0095045	1	0.0094606	1	2.4183e-05	0.0139
amp_7p11.2	163 (46%)	188	2.7764e-12	2.02e-09	0.00024271	0.122	0.89885	1	0.93138	1	0.041664	1	0.13726	1	0.13785	1	0.20464	1	0.04499	1	0.0090811	1
amp_7q21.2	159 (45%)	192	5.8736e-12	4.25e-09	0.0007712	0.352	0.19989	1	0.97979	1	0.51088	1	0.29654	1	0.19767	1	0.10376	1	0.082012	1	0.037262	1
amp_8p23.1	141 (40%)	210	9.1103e-05	0.0492	0.00016984	0.0868	0.59543	1	0.58515	1	0.061031	1	0.0051683	1	0.83816	1	0.11125	1	0.18298	1	0.0095801	1
amp_8q24.21	244 (70%)	107	2.0116e-07	0.000132	0.00082397	0.374	0.36968	1	0.15877	1	0.0074852	1	0.0085574	1	0.0014185	0.614	0.00047376	0.223	0.00012278	0.064	0.0011968	0.525
amp_9p24.1	55 (16%)	296	6.1822e-05	0.0342	0.443	1	0.62209	1	0.021102	1	0.13955	1	0.017583	1	0.10049	1	0.069093	1	0.10306	1	0.39697	1
amp_9p13.3	66 (19%)	285	0.0034483	1	0.22432	1	0.26328	1	0.62115	1	0.019319	1	0.020636	1	0.013549	1	0.47381	1	0.10098	1	0.31056	1
amp_9q34.3	93 (26%)	258	0.00025671	0.128	0.10893	1	0.72241	1	0.21723	1	0.033012	1	0.0036879	1	0.18336	1	0.37084	1	0.006788	1	0.082159	1
amp_10p11.22	95 (27%)	256	1.8411e-13	1.36e-10	1.7775e-06	0.00113	0.14425	1	0.60723	1	0.00064055	0.294	0.0022379	0.935	5.1079e-05	0.0286	0.00043619	0.207	0.0044695	1	0.00025644	0.128
amp_10q22.2	66 (19%)	285	1.3832e-09	9.71e-07	0.0088452	1	0.02757	1	0.47391	1	0.012941	1	0.011749	1	0.040363	1	0.14345	1	0.089456	1	0.033496	1
amp_10q26.13	71 (20%)	280	1.2894e-05	0.00762	0.0063576	1	0.037272	1	0.55366	1	0.0039336	1	0.0078824	1	0.18519	1	0.062646	1	1	1	0.028586	1
amp_11p13	66 (19%)	285	0.0029183	1	0.024317	1	0.64226	1	0.26302	1	0.00095356	0.428	1.1488e-05	0.00686	0.0048284	1	0.00010472	0.0556	0.13126	1	0.0028696	1
amp_11q13.3	85 (24%)	266	2.0564e-09	1.44e-06	0.012207	1	0.18591	1	0.76865	1	0.10673	1	0.0023605	0.973	5.6246e-06	0.00344	0.002036	0.861	6.9982e-05	0.0384	0.017575	1
amp_12p12.1	105 (30%)	246	7.4659e-06	0.00451	0.16434	1	0.42336	1	0.062255	1	0.18397	1	0.64174	1	0.04525	1	0.09113	1	0.012647	1	0.25003	1
amp_12q15	91 (26%)	260	1.999e-05	0.0116	0.44212	1	0.21104	1	0.42808	1	0.26337	1	0.50925	1	0.4838	1	0.095673	1	0.13616	1	0.54421	1
amp_13q12.3	136 (39%)	215	4.5782e-15	3.45e-12	6.2833e-05	0.0347	0.32276	1	0.54494	1	0.015211	1	0.21659	1	0.00016451	0.0844	0.00053446	0.249	0.013632	1	3.8079e-05	0.0216
amp_13q22.1	141 (40%)	210	3.5108e-15	2.65e-12	1.655e-05	0.00975	0.19505	1	0.22957	1	1.2615e-05	0.00748	0.0019977	0.848	1.2083e-05	0.0072	9.1974e-06	0.00552	0.00047711	0.224	2.4729e-08	1.68e-05
amp_15q26.1	83 (24%)	268	6.1844e-16	4.68e-13	1.9505e-05	0.0113	0.44726	1	0.69699	1	1.8814e-05	0.0109	4.3262e-06	0.00268	0.0070978	1	0.012311	1	0.010853	1	0.0036582	1
amp_17q12	110 (31%)	241	1.2312e-18	9.37e-16	9.0074e-08	6e-05	0.78008	1	0.5412	1	0.00010575	0.056	0.00029278	0.145	2.8504e-06	0.00179	0.00039953	0.191	0.04772	1	0.0010208	0.456
amp_18q11.2	112 (32%)	239	3.7922e-10	2.68e-07	0.0068623	1	0.29152	1	0.078182	1	0.01331	1	0.02659	1	0.0018022	0.768	0.0010324	0.459	0.021831	1	0.0090075	1
amp_19p13.2	40 (11%)	311	0.00044561	0.211	0.13808	1	0.86901	1	0.3264	1	0.72872	1	0.82916	1	0.73806	1	0.59397	1	0.87755	1	0.25756	1
amp_19q12	108 (31%)	243	3.9296e-22	3.03e-19	1.8802e-08	1.28e-05	0.0060919	1	0.16092	1	3.2577e-14	2.43e-11	3.3377e-08	2.26e-05	2.4594e-07	0.000161	1.3693e-13	1.02e-10	0.038423	1	1.8661e-13	1.38e-10
amp_20q13.2	233 (66%)	118	1.5839e-21	1.22e-18	5.4556e-10	3.85e-07	0.0063412	1	0.9294	1	5.6597e-08	3.79e-05	2.7609e-05	0.0158	1.0784e-07	7.13e-05	4.5543e-12	3.3e-09	0.010857	1	1.2261e-10	8.73e-08
amp_xq27.3	67 (19%)	284	0.00029078	0.144	0.0017641	0.753	0.58619	1	0.16714	1	0.17597	1	0.34489	1	0.030081	1	0.9696	1	0.04305	1	0.14856	1
del_1p36.11	100 (28%)	251	1.1793e-14	8.86e-12	3.2017e-10	2.27e-07	0.15705	1	0.23512	1	0.00032969	0.16	0.00010797	0.057	7.4629e-06	0.00451	1.398e-06	0.000891	0.0026699	1	7.8527e-06	0.00472
del_1p13.2	70 (20%)	281	9.6106e-13	7.03e-10	1.0327e-06	0.000662	0.077683	1	0.1911	1	0.00062784	0.289	0.00043072	0.205	0.0016655	0.716	0.0026401	1	0.39691	1	0.0092152	1
del_1q44	27 (8%)	324	0.022524	1	0.005429	1	0.17646	1	0.024255	1	0.35028	1	0.014264	1	0.0090895	1	0.015549	1	0.010167	1	0.092911	1
del_2q32.1	49 (14%)	302	0.010504	1	0.066047	1	0.46185	1	0.11598	1	0.11035	1	0.68317	1	0.045611	1	0.003917	1	0.47091	1	0.0158	1
del_2q37.2	53 (15%)	298	0.00020776	0.106	0.00046024	0.217	0.2682	1	0.12446	1	0.0045801	1	0.2644	1	0.00051632	0.241	7.7001e-06	0.00464	0.10306	1	1.478e-05	0.00872
del_3p26.1	109 (31%)	242	1.0227e-11	7.37e-09	0.00077159	0.352	0.33767	1	0.69262	1	0.0062731	1	0.0012264	0.536	0.00032903	0.16	0.00056859	0.264	0.011202	1	0.00016317	0.0839
del_3p14.2	127 (36%)	224	1.9822e-09	1.39e-06	1.2751e-05	0.00755	0.40193	1	0.9043	1	9.2143e-05	0.0496	3.7222e-05	0.0211	0.00031101	0.152	0.0027699	1	0.062984	1	2.9975e-05	0.0171
del_3q26.31	43 (12%)	308	3.8363e-06	0.00239	1.7685e-05	0.0103	0.12809	1	0.45595	1	0.00033771	0.163	0.00049527	0.232	0.00012845	0.0667	0.009881	1	0.012663	1	0.016619	1
del_4p16.3	135 (38%)	216	5.2491e-13	3.85e-10	0.00023664	0.12	0.45302	1	0.027909	1	1.0535e-05	0.0063	3.6612e-05	0.0208	2.4234e-06	0.00153	4.2578e-08	2.87e-05	0.00023677	0.12	9.585e-08	6.36e-05
del_4q22.1	153 (44%)	198	2.0251e-22	1.57e-19	6.1985e-06	0.00378	0.1097	1	0.3293	1	0.0023912	0.98	0.00032429	0.158	0.0023933	0.98	8.9956e-05	0.0487	0.11001	1	2.1326e-05	0.0123
del_4q34.3	155 (44%)	196	1.8614e-21	1.43e-18	1.0984e-06	0.000702	0.050961	1	0.57188	1	1.2415e-05	0.00737	2.7787e-05	0.0159	5.0264e-06	0.00309	2.9793e-07	0.000195	0.0043995	1	2.6741e-07	0.000175
del_5q11.2	129 (37%)	222	9.4094e-26	7.33e-23	4.7257e-15	3.56e-12	0.24069	1	0.42823	1	5.103e-13	3.75e-10	3.2953e-12	2.39e-09	9.6298e-11	6.87e-08	1.2096e-11	8.71e-09	2.6707e-08	1.81e-05	5.642e-15	4.24e-12
del_5q23.2	116 (33%)	235	1.6507e-25	1.28e-22	1.186e-14	8.9e-12	0.11868	1	0.46233	1	4.199e-13	3.09e-10	5.9638e-11	4.26e-08	1.5595e-11	1.12e-08	3.7487e-10	2.66e-07	9.4726e-08	6.3e-05	1.8041e-12	1.31e-09
del_6p25.3	85 (24%)	266	2.4639e-09	1.72e-06	4.3717e-05	0.0246	0.13445	1	0.090319	1	9.4835e-05	0.0508	1.8078e-05	0.0105	0.0022535	0.94	0.00061634	0.284	0.028794	1	0.011161	1
del_6q14.1	69 (20%)	282	2.4971e-08	1.7e-05	0.00037457	0.18	0.2178	1	0.86099	1	0.00042489	0.203	0.078101	1	0.81107	1	0.026336	1	0.76655	1	0.022232	1
del_6q26	77 (22%)	274	5.4211e-07	0.000352	0.0094832	1	0.77088	1	0.2273	1	0.0010363	0.46	0.0002646	0.132	0.49439	1	0.018109	1	0.22063	1	0.14472	1
del_7q31.1	50 (14%)	301	8.1092e-09	5.62e-06	6.9857e-06	0.00424	0.71098	1	0.64737	1	0.0044721	1	0.012964	1	0.0082144	1	0.034216	1	5.8893e-05	0.0326	0.067862	1
del_7q36.3	75 (21%)	276	9.5866e-21	7.34e-18	9.732e-05	0.0521	0.38825	1	0.79977	1	3.1727e-06	0.00199	5.4286e-06	0.00333	9.7828e-05	0.0522	8.1605e-07	0.000526	0.0021037	0.887	6.5235e-06	0.00397
del_8p23.2	93 (26%)	258	1.8465e-14	1.38e-11	0.00024254	0.122	0.061859	1	0.28302	1	7.1047e-06	0.00431	4.9024e-06	0.00301	0.0042104	1	1.0732e-06	0.000687	0.016897	1	1.7688e-06	0.00112
del_9p23	149 (42%)	202	2.8671e-22	2.22e-19	6.8086e-05	0.0374	0.028121	1	0.20766	1	4.4313e-06	0.00273	0.00021692	0.11	0.01108	1	0.0022996	0.952	0.55909	1	6.4396e-05	0.0355
del_9p21.3	145 (41%)	206	4.3182e-23	3.35e-20	3.7787e-07	0.000246	4.9251e-05	0.0276	0.022662	1	2.5597e-09	1.78e-06	1.7266e-05	0.0101	0.012037	1	0.00044217	0.21	0.17189	1	3.7754e-06	0.00235
del_9q21.11	90 (26%)	261	4.077e-13	3.01e-10	0.003663	1	0.14062	1	0.1247	1	0.0010886	0.481	0.018709	1	0.00081084	0.369	0.0035894	1	0.051816	1	1.7373e-05	0.0102
del_10q22.3	56 (16%)	295	3.4069e-11	2.44e-08	0.024799	1	0.73023	1	0.76077	1	0.00015142	0.0783	0.0023774	0.977	0.0012481	0.544	0.0067602	1	0.067771	1	0.013028	1
del_10q23.31	84 (24%)	267	1.4599e-13	1.08e-10	9.2553e-05	0.0497	0.065512	1	0.33174	1	8.6403e-07	0.000556	0.0021512	0.904	5.4699e-05	0.0304	0.00011634	0.061	0.09342	1	0.00031603	0.155
del_11p15.4	74 (21%)	277	6.0478e-13	4.43e-10	5.2613e-05	0.0293	1.8401e-06	0.00116	0.0016645	0.716	0.00073948	0.339	7.6642e-05	0.0418	0.17937	1	0.0057545	1	0.49832	1	0.0031319	1
del_11q23.2	75 (21%)	276	1.231e-05	0.00732	0.010483	1	0.56652	1	0.72662	1	0.0022196	0.93	0.53085	1	0.18195	1	0.074532	1	0.30118	1	0.087337	1
del_12p13.1	54 (15%)	297	1.7713e-13	1.31e-10	2.984e-08	2.02e-05	0.51926	1	1	1	2.9624e-06	0.00186	6.305e-07	0.000409	0.06055	1	0.028125	1	0.12918	1	0.00029273	0.145
del_13q12.11	50 (14%)	301	1.4443e-08	9.88e-06	0.099795	1	0.41333	1	0.13777	1	0.04605	1	0.024495	1	0.34597	1	0.15866	1	0.53304	1	0.05831	1
del_14q12	91 (26%)	260	3.4571e-12	2.51e-09	5.5368e-05	0.0307	0.58408	1	0.75459	1	0.000346	0.167	0.00016535	0.0847	0.00017612	0.0898	0.0014072	0.611	0.013631	1	0.00010377	0.0552
del_14q32.33	102 (29%)	249	1.5581e-10	1.11e-07	0.00013954	0.0723	0.97705	1	0.37771	1	0.00055669	0.259	7.4475e-06	0.00451	0.010247	1	0.041346	1	0.0029056	1	0.00087806	0.396
del_15q15.1	97 (28%)	254	3.8967e-13	2.88e-10	2.985e-07	0.000195	0.0036937	1	0.058303	1	5.6329e-08	3.77e-05	1.3234e-08	9.09e-06	4.0719e-06	0.00253	9.599e-09	6.61e-06	6.8081e-05	0.0374	9.8239e-07	0.000632
del_16p13.3	71 (20%)	280	3.9896e-14	2.98e-11	0.00046725	0.22	0.69762	1	0.95532	1	8.0643e-09	5.6e-06	2.3393e-09	1.64e-06	4.2479e-06	0.00263	1.7247e-05	0.0101	1.0236e-06	0.000657	2.4337e-06	0.00153
del_16q23.1	141 (40%)	210	1.4591e-08	9.97e-06	0.01253	1	0.46402	1	0.13498	1	0.0016053	0.692	0.00011184	0.0589	0.0010535	0.467	0.0046792	1	0.00029585	0.146	0.00012067	0.0631
del_17p12	134 (38%)	217	7.0448e-25	5.47e-22	1.3369e-14	1e-11	0.39789	1	0.88864	1	9.4025e-09	6.49e-06	5.5845e-08	3.75e-05	9.9438e-06	0.00596	4.3585e-08	2.93e-05	0.00011372	0.0598	4.3147e-11	3.08e-08
del_17q24.3	64 (18%)	287	1.3575e-08	9.31e-06	2.2883e-05	0.0132	0.1827	1	0.44773	1	0.0012058	0.528	0.0039769	1	0.0027928	1	0.0051726	1	0.023586	1	0.0054795	1
del_18q21.2	162 (46%)	189	2.5945e-18	1.97e-15	0.00011478	0.0603	0.66232	1	0.47202	1	0.00032424	0.158	0.0023481	0.97	0.00029639	0.146	0.013137	1	0.011375	1	0.021869	1
del_19p13.3	123 (35%)	228	3.9242e-29	3.06e-26	5.6652e-14	4.22e-11	0.0021027	0.887	0.34827	1	4.4591e-17	3.38e-14	8.76e-19	6.68e-16	2.6437e-09	1.84e-06	1.2125e-21	9.35e-19	4.7829e-05	0.0268	1.2235e-19	9.36e-17
del_19q13.11	53 (15%)	298	6.944e-10	4.89e-07	8.1121e-09	5.62e-06	0.20366	1	0.49942	1	0.0001212	0.0633	0.00099873	0.447	7.916e-05	0.043	2.4525e-05	0.0141	0.0011203	0.493	0.00012789	0.0665
del_20p12.1	28 (8%)	323	0.0058276	1	0.00091974	0.414	0.64401	1	1	1	0.009171	1	0.067884	1	0.0032098	1	0.17339	1	0.48199	1	0.040052	1
del_21q11.2	130 (37%)	221	4.0595e-11	2.91e-08	3.8569e-05	0.0218	0.34044	1	0.19399	1	0.0016939	0.725	1.2641e-06	0.000806	0.00033685	0.163	0.0072385	1	0.0043041	1	0.0059899	1
del_21q22.13	142 (40%)	209	4.2352e-13	3.12e-10	0.0056092	1	0.10262	1	0.44014	1	0.0015471	0.668	4.7658e-06	0.00294	0.0022604	0.94	0.0010216	0.456	0.014305	1	0.0033014	1
del_22q13.31	122 (35%)	229	4.5249e-19	3.45e-16	4.9627e-08	3.33e-05	0.048934	1	0.50256	1	0.00083712	0.379	0.0001592	0.0821	7.8522e-05	0.0427	7.4752e-08	4.99e-05	0.027395	1	4.3775e-06	0.00271
del_xp22.2	66 (19%)	285	2.44e-11	1.75e-08	7.9552e-05	0.0431	0.34916	1	0.85906	1	0.00028399	0.141	0.029362	1	0.054454	1	0.00010157	0.0541	0.33951	1	0.024855	1
del_xp21.1	63 (18%)	288	3.4786e-08	2.35e-05	0.018624	1	0.092228	1	0.57358	1	0.02426	1	0.079292	1	0.57573	1	0.18525	1	0.44391	1	0.35507	1
del_xq21.33	45 (13%)	306	7.2808e-05	0.0398	0.00041348	0.198	0.79725	1	0.76523	1	0.0077396	1	0.012211	1	0.015816	1	0.097408	1	0.031848	1	0.050816	1
