Clinical Features Time to Death AGE NEOPLASM.DISEASESTAGE PATHOLOGY.T.STAGE PATHOLOGY.N.STAGE GENDER nMutated (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q NMU 7 (21%) 27 0.95317 1 0.25823 1 0.50246 1 0.83024 1 0.018062 1 0.39832 1 LPPR2 3 (9%) 31 0.0026036 1 0.72617 1 NA NA NA NA 0.25287 1 1 1 SYT8 6 (18%) 28 0.64776 1 0.26958 1 0.91593 1 1 1 1 1 0.17484 1 RINL 8 (24%) 26 0.6612 1 0.51596 1 0.85927 1 0.51003 1 1 1 0.68802 1 OBSCN 15 (44%) 19 0.38243 1 0.059131 1 0.7483 1 0.59219 1 1 1 1 1 MAP1S 4 (12%) 30 0.27997 1 0.1611 1 0.69349 1 1 1 0.45448 1 1 1 GPRIN2 4 (12%) 30 0.8844 1 0.90738 1 0.35632 1 1 1 1 1 0.60117 1 ATP9B 3 (9%) 31 0.32774 1 0.12111 1 NA NA NA NA 0.25287 1 1 1 RREB1 4 (12%) 30 0.95437 1 0.16622 1 1 1 1 1 0.45448 1 1 1 IDUA 6 (18%) 28 0.6365 1 0.72661 1 0.78982 1 1 1 1 1 1 1 RGS9BP 6 (18%) 28 0.79122 1 0.10316 1 0.088417 1 0.32702 1 1 1 0.65618 1 WDR34 4 (12%) 30 0.7594 1 0.064203 1 0.60153 1 0.70443 1 0.35961 1 0.60117 1 NOTCH2 3 (9%) 31 0.31978 1 0.96789 1 NA NA NA NA 0.13333 1 1 1 TMEM189 3 (9%) 31 0.3373 1 0.24368 1 NA NA NA NA 1 1 1 1 TAF5 5 (15%) 29 0.38256 1 0.45507 1 0.69349 1 0.7878 1 0.45448 1 0.33529 1 LRP11 4 (12%) 30 0.31159 1 0.72369 1 NA NA NA NA 1 1 0.60117 1 FPGS 7 (21%) 27 0.3141 1 0.023983 1 0.92293 1 0.83024 1 0.22452 1 1 1 TOR3A 13 (38%) 21 0.30432 1 0.94726 1 0.10831 1 0.097895 1 0.61106 1 0.48127 1 ZNF517 17 (50%) 17 0.493 1 0.26689 1 0.79185 1 0.67941 1 0.5977 1 0.49351 1 GLTPD2 10 (29%) 24 0.60837 1 0.23463 1 0.67376 1 1 1 1 1 0.70799 1 SEMA5B 7 (21%) 27 0.59708 1 0.44648 1 0.49225 1 0.41208 1 1 1 1 1 TNIP2 3 (9%) 31 0.28713 1 0.77404 1 NA NA NA NA 1 1 1 1 HHIPL1 5 (15%) 29 0.90877 1 0.9685 1 0.31166 1 0.66048 1 0.11877 1 1 1 HECTD2 3 (9%) 31 0.011829 1 0.33697 1 0.82923 1 0.70443 1 1 1 0.22727 1 ADAD2 10 (29%) 24 0.1636 1 0.74218 1 0.34283 1 0.85346 1 0.56322 1 1 1 CTNNB1 7 (21%) 27 0.0051493 1 0.23929 1 0.71188 1 0.51003 1 0.22452 1 0.085448 1 ZFPM1 19 (56%) 15 0.07841 1 0.82806 1 0.022404 1 0.44776 1 0.61292 1 1 1 CLDN23 4 (12%) 30 0.9959 1 0.38988 1 0.53147 1 0.42402 1 0.45448 1 1 1 CCDC105 4 (12%) 30 0.57089 1 0.58127 1 0.35632 1 0.32702 1 1 1 0.10264 1 NOL9 7 (21%) 27 0.99804 1 0.0055772 1 0.24412 1 0.37047 1 1 1 1 1 ZNF598 7 (21%) 27 0.55444 1 0.0053002 1 0.04751 1 0.043931 1 0.55687 1 1 1 THEM4 6 (18%) 28 0.080044 1 0.82716 1 1 1 0.7878 1 0.45448 1 0.65618 1 LRIG1 16 (47%) 18 0.065874 1 0.99678 1 0.59254 1 0.19354 1 1 1 0.30283 1 MUC5B 8 (24%) 26 0.54893 1 0.4116 1 0.7145 1 0.83024 1 0.55687 1 0.68802 1 AMDHD1 10 (29%) 24 0.93737 1 0.34478 1 0.6631 1 1 1 1 1 0.70799 1 RNF149 3 (9%) 31 0.36985 1 0.60931 1 0.099617 1 0.065134 1 1 1 0.22727 1 MSH3 3 (9%) 31 0.032614 1 0.91663 1 0.16092 1 0.10454 1 0.35961 1 1 1 ALPPL2 3 (9%) 31 0.32774 1 0.82817 1 0.82923 1 0.70443 1 1 1 1 1 SNED1 4 (12%) 30 0.1948 1 0.70376 1 0.53147 1 0.42402 1 0.074986 1 1 1 OPRD1 11 (32%) 23 0.97055 1 0.65248 1 0.87846 1 0.73831 1 1 1 0.02551 1 CCDC102A 11 (32%) 23 0.21745 1 0.12132 1 0.029807 1 0.075072 1 0.27203 1 1 1 KCTD3 4 (12%) 30 0.43806 1 0.6807 1 0.82923 1 0.70443 1 0.35961 1 1 1 C1ORF106 6 (18%) 28 0.72843 1 0.97982 1 0.40569 1 0.28771 1 1 1 0.17484 1 KCNK17 9 (26%) 25 0.17619 1 0.67224 1 0.73773 1 1 1 0.28352 1 0.43843 1 LACTB 11 (32%) 23 0.78958 1 0.2839 1 0.085195 1 0.23301 1 0.27203 1 1 1 TRIOBP 9 (26%) 25 0.92888 1 0.59412 1 0.53197 1 0.2131 1 1 1 1 1 SARM1 5 (15%) 29 0.4377 1 0.43893 1 1 1 1 1 1 1 1 1 ERCC2 11 (32%) 23 0.18486 1 0.83482 1 0.94243 1 1 1 0.61106 1 0.46464 1 NEFH 4 (12%) 30 0.98682 1 0.84812 1 0.53147 1 0.7878 1 0.074986 1 1 1 KBTBD13 8 (24%) 26 0.48198 1 0.27129 1 0.6631 1 0.53391 1 0.28352 1 0.68802 1 IRX3 9 (26%) 25 0.3609 1 0.80895 1 0.21603 1 0.61939 1 1 1 0.11754 1 MUC2 7 (21%) 27 0.24279 1 0.13335 1 0.058019 1 0.027073 1 0.55687 1 0.085448 1 GARS 14 (41%) 20 0.45947 1 0.44282 1 0.11619 1 0.43641 1 0.61292 1 0.72828 1 UQCRFS1 7 (21%) 27 0.70193 1 0.90702 1 0.49225 1 0.41208 1 0.22452 1 1 1 ZNF628 5 (15%) 29 0.0097161 1 0.74705 1 0.7618 1 1 1 1 1 1 1 ASPDH 11 (32%) 23 0.65312 1 0.72382 1 0.28418 1 0.64411 1 1 1 0.46464 1 TPO 10 (29%) 24 0.91633 1 0.77192 1 0.19774 1 0.3388 1 0.28736 1 0.25873 1 GLTSCR2 4 (12%) 30 0.45274 1 0.35034 1 0.69349 1 0.7878 1 1 1 0.60117 1 PANK2 7 (21%) 27 0.83276 1 0.89959 1 0.84937 1 0.83024 1 0.16913 1 0.39832 1 RNF39 3 (9%) 31 0.078183 1 0.069005 1 NA NA NA NA 0.25287 1 1 1 MAL2 7 (21%) 27 0.95712 1 0.012799 1 0.43068 1 0.023985 1 1 1 0.39832 1 ZAR1 11 (32%) 23 0.16807 1 0.92442 1 0.25016 1 0.35818 1 1 1 0.14107 1 KRTAP5-5 3 (9%) 31 0.011829 1 0.33697 1 0.82923 1 0.70443 1 1 1 0.22727 1 CRIPAK 6 (18%) 28 0.3709 1 0.17938 1 0.7145 1 0.83024 1 1 1 0.65618 1 TP53 7 (21%) 27 0.028326 1 0.18028 1 0.015031 1 0.0025767 1 0.16913 1 1 1 BHLHE22 4 (12%) 30 0.38101 1 0.98451 1 1 1 0.7878 1 0.45448 1 1 1 RGMB 3 (9%) 31 0.57763 1 0.93172 1 0.82923 1 0.70443 1 0.35961 1 1 1 APOE 6 (18%) 28 0.59708 1 0.17539 1 0.91593 1 1 1 1 1 0.65618 1 MEN1 3 (9%) 31 0.91049 1 0.12111 1 NA NA NA NA 1 1 1 1 RASIP1 4 (12%) 30 0.30553 1 0.44533 1 1 1 0.7878 1 0.45448 1 0.60117 1 ZC3H12D 3 (9%) 31 0.11296 1 0.22177 1 NA NA NA NA 1 1 1 1 TSC22D2 7 (21%) 27 0.11821 1 0.85029 1 0.31166 1 0.036841 1 0.16913 1 1 1 COQ2 5 (15%) 29 0.79122 1 0.30639 1 0.91593 1 1 1 1 1 0.33529 1 DOK7 5 (15%) 29 0.20405 1 0.56383 1 0.14669 1 0.063113 1 1 1 1 1 KNDC1 7 (21%) 27 0.2508 1 0.49687 1 0.40569 1 0.28771 1 1 1 1 1 PDCD6 3 (9%) 31 0.74365 1 0.66146 1 0.041598 1 0.015873 1 0.35961 1 1 1 ATP6V0E2 4 (12%) 30 0.28897 1 0.047952 1 0.50192 1 0.38916 1 1 1 0.60117 1 HES3 3 (9%) 31 0.38511 1 0.19846 1 1 1 1 1 1 1 1 1 PRKAR1A 3 (9%) 31 0.058277 1 0.87692 1 0.16092 1 0.10454 1 0.35961 1 0.22727 1 ATOH8 3 (9%) 31 0.18791 1 0.99029 1 0.82923 1 0.70443 1 0.35961 1 1 1 BTBD11 4 (12%) 30 0.054999 1 0.64635 1 0.60153 1 0.42402 1 0.45448 1 1 1 PLIN5 4 (12%) 30 0.70366 1 0.28318 1 0.78982 1 1 1 0.45448 1 1 1 ASB16 4 (12%) 30 0.86743 1 0.48818 1 1 1 0.7878 1 1 1 0.60117 1 SCRT1 4 (12%) 30 1.6825e-05 0.00935 0.00025379 0.141 0.69349 1 0.7878 1 0.074986 1 1 1 NPTX1 5 (15%) 29 0.23669 1 0.10064 1 0.14669 1 0.063113 1 1 1 1 1 LRRN4 3 (9%) 31 0.43806 1 0.39735 1 0.60153 1 1 1 0.35961 1 1 1 CCDC96 4 (12%) 30 0.3373 1 0.13562 1 0.82923 1 0.70443 1 0.35961 1 0.60117 1 PCMTD1 3 (9%) 31 0.8511 1 0.43878 1 NA NA NA NA 1 1 1 1 GLI3 5 (15%) 29 0.7687 1 0.023358 1 0.60153 1 0.42402 1 1 1 1 1 MN1 3 (9%) 31 0.13834 1 0.081601 1 1 1 0.38916 1 0.35961 1 0.22727 1 C9ORF66 3 (9%) 31 0.83435 1 0.36505 1 0.50192 1 0.23591 1 1 1 1 1 MADCAM1 3 (9%) 31 0.004495 1 5.59e-05 0.031 0.16092 1 0.038862 1 0.039409 1 1 1 KRTAP10-7 3 (9%) 31 0.28897 1 0.76499 1 NA NA NA NA 1 1 1 1 ARRDC4 5 (15%) 29 0.65218 1 0.57979 1 0.91593 1 1 1 0.53841 1 1 1 VARS 3 (9%) 31 0.25427 1 0.2735 1 NA NA NA NA 1 1 1 1 PLEC 6 (18%) 28 0.20405 1 0.3867 1 0.46875 1 1 1 0.55687 1 0.65618 1 RCCD1 3 (9%) 31 0.34797 1 0.60519 1 NA NA NA NA 1 1 1 1