Clinical Features CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Chi-square test_P Chi-square test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q amp_1q22 17 (19%) 73 0.011102 1 0.0010013 0.329 0.0027506 0.875 8.8899e-05 0.0308 0.12924 1 0.27048 1 0.076459 1 0.17703 1 amp_4p16.3 41 (46%) 49 0.0028211 0.894 0.5441 1 0.013268 1 0.016506 1 0.48471 1 0.48882 1 0.55461 1 0.55563 1 amp_4q35.1 29 (32%) 61 4.6207e-05 0.0161 0.22993 1 0.00089768 0.297 0.010072 1 0.05792 1 0.18131 1 0.15473 1 0.32718 1 amp_5p15.33 65 (72%) 25 5.2134e-05 0.0181 0.86613 1 0.010513 1 0.070548 1 0.044463 1 0.81965 1 0.12157 1 0.59912 1 amp_5q35.3 63 (70%) 27 8.4875e-08 3.06e-05 0.0016967 0.55 2.199e-06 0.000781 1.2377e-05 0.00437 0.0062601 1 0.31133 1 0.024134 1 0.63085 1 amp_6p21.31 19 (21%) 71 0.11001 1 0.75315 1 0.080882 1 1 1 0.1308 1 0.22506 1 0.14675 1 0.17693 1 amp_6q24.3 19 (21%) 71 0.0068876 1 0.87342 1 0.047255 1 0.86974 1 0.64491 1 0.73692 1 0.8159 1 0.90261 1 amp_7p22.1 54 (60%) 36 0.0089449 1 0.46209 1 0.0080191 1 0.058924 1 0.53386 1 0.26998 1 0.4243 1 0.16934 1 amp_9q31.3 34 (38%) 56 0.00016983 0.0584 0.025341 1 0.029766 1 0.0031078 0.976 0.049889 1 0.1003 1 0.037939 1 0.1038 1 amp_12q14.1 70 (78%) 20 0.00014237 0.0491 0.25479 1 0.023993 1 0.079172 1 0.44699 1 0.55595 1 0.075222 1 0.52106 1 amp_14q11.2 27 (30%) 63 8.6682e-05 0.0301 0.017958 1 3.8043e-05 0.0134 5.9869e-07 0.000214 0.00029534 0.0995 0.0020886 0.67 0.00022584 0.0768 0.00075315 0.251 amp_16p13.3 50 (56%) 40 1.335e-07 4.78e-05 0.25793 1 0.0001947 0.0666 0.00058538 0.196 0.074424 1 0.55406 1 0.016123 1 0.84091 1 amp_16q22.1 56 (62%) 34 9.3098e-07 0.000331 0.38712 1 0.029451 1 0.0044987 1 0.063487 1 0.7862 1 0.036335 1 1 1 amp_16q24.2 49 (54%) 41 9.8611e-08 3.54e-05 0.029892 1 0.00027134 0.0917 3.9093e-05 0.0137 0.06474 1 0.24865 1 0.02918 1 0.53955 1 amp_17q25.3 18 (20%) 72 0.12376 1 0.65224 1 0.12618 1 0.50086 1 0.39822 1 0.65653 1 0.5402 1 0.37031 1 amp_19p13.12 58 (64%) 32 0.0031789 0.992 0.03079 1 0.0022648 0.725 0.0013174 0.431 0.3255 1 0.62579 1 0.24061 1 0.25632 1 amp_19q12 56 (62%) 34 0.0096222 1 0.019287 1 0.00195 0.63 0.0025686 0.819 0.17763 1 0.31122 1 0.12524 1 0.1136 1 amp_xp11.22 49 (54%) 41 0.00018879 0.0648 0.90226 1 0.034064 1 0.15667 1 0.71742 1 0.3446 1 0.85341 1 0.21675 1 amp_xq28 46 (51%) 44 0.00034531 0.116 0.74124 1 0.0092143 1 0.1261 1 0.48257 1 0.20423 1 0.67741 1 0.27287 1 del_1p36.23 37 (41%) 53 0.036089 1 0.015642 1 0.13621 1 0.02011 1 0.92426 1 0.38999 1 0.69311 1 0.41807 1 del_1q43 18 (20%) 72 0.10869 1 0.037827 1 0.58789 1 0.087502 1 0.49073 1 0.24811 1 0.65934 1 0.30728 1 del_2q22.1 18 (20%) 72 0.0020401 0.657 0.0044211 1 0.23739 1 0.15308 1 0.3194 1 0.17788 1 0.39276 1 0.28049 1 del_2q37.3 21 (23%) 69 0.0034275 1 0.031265 1 0.29182 1 0.19867 1 0.43298 1 0.46261 1 0.6203 1 0.63087 1 del_3q13.31 23 (26%) 67 0.018427 1 0.26381 1 0.01394 1 0.20205 1 0.27452 1 0.097847 1 0.075712 1 0.14766 1 del_4q34.3 25 (28%) 65 0.009858 1 0.044141 1 0.022669 1 0.029613 1 0.034907 1 0.16565 1 0.11789 1 0.10425 1 del_4q35.1 28 (31%) 62 0.046893 1 0.033139 1 0.097365 1 0.069661 1 0.34333 1 0.64348 1 0.53886 1 0.53166 1 del_6p24.3 20 (22%) 70 0.0063418 1 0.90041 1 0.59423 1 0.68687 1 1 1 0.73692 1 0.87672 1 0.90261 1 del_6q26 21 (23%) 69 0.033652 1 0.88062 1 0.32142 1 0.32204 1 0.49062 1 0.66231 1 0.41638 1 0.52412 1 del_7q32.3 9 (10%) 81 0.23224 1 0.030549 1 0.17578 1 0.069845 1 0.89549 1 0.44636 1 1 1 0.6028 1 del_9p23 24 (27%) 66 0.00095041 0.314 0.0054579 1 3.5438e-05 0.0125 0.0014644 0.477 0.006903 1 0.31187 1 0.0453 1 0.34722 1 del_9p21.3 27 (30%) 63 0.00065727 0.22 0.0031622 0.99 9.7103e-06 0.00344 0.00022044 0.0752 0.016887 1 0.20356 1 0.07662 1 0.213 1 del_10q23.1 11 (12%) 79 0.037879 1 0.19393 1 0.2372 1 1 1 1 1 0.51773 1 0.89096 1 0.52756 1 del_11p15.5 27 (30%) 63 0.0014976 0.487 0.018859 1 0.091749 1 0.13268 1 0.12294 1 0.1087 1 0.19878 1 0.15091 1 del_11q14.1 25 (28%) 65 0.00024071 0.0816 0.0059292 1 0.22345 1 0.34313 1 0.27743 1 0.37095 1 0.4194 1 0.58541 1 del_12q14.2 5 (6%) 85 0.18885 1 0.24567 1 0.1771 1 0.50521 1 0.59421 1 1 1 0.10277 1 1 1 del_13q14.2 42 (47%) 48 0.0030094 0.95 0.082284 1 0.33291 1 0.41613 1 1 1 1 1 0.90346 1 0.84091 1 del_14q21.2 20 (22%) 70 0.0072879 1 0.9141 1 0.3078 1 0.099161 1 0.36412 1 0.35692 1 0.20485 1 0.36298 1 del_16p13.3 7 (8%) 83 0.10137 1 0.46296 1 0.54354 1 1 1 0.024126 1 0.45081 1 0.044965 1 0.41134 1 del_16q23.1 9 (10%) 81 0.040819 1 0.50758 1 0.016961 1 0.16732 1 0.14101 1 0.85474 1 0.29901 1 0.85148 1 del_17q11.2 24 (27%) 66 0.0034283 1 0.0064416 1 0.10391 1 0.17477 1 0.23698 1 0.27868 1 0.23611 1 0.18276 1 del_17q21.31 26 (29%) 64 0.0030063 0.95 0.0083759 1 0.076674 1 0.083598 1 0.035014 1 0.074009 1 0.044678 1 0.036865 1 del_17q24.2 24 (27%) 66 0.00086737 0.288 0.01126 1 0.16249 1 0.048471 1 0.14793 1 0.20356 1 0.17206 1 0.11647 1 del_18q21.2 36 (40%) 54 0.075734 1 0.30783 1 0.81128 1 0.9418 1 0.47081 1 0.47187 1 0.73169 1 0.62983 1 del_20p12.1 12 (13%) 78 0.0011793 0.387 0.58845 1 0.042353 1 0.025655 1 0.0063279 1 0.54687 1 0.014252 1 0.55562 1 del_22q12.1 50 (56%) 40 0.039056 1 0.13382 1 0.73391 1 0.41667 1 0.62893 1 0.51049 1 0.47062 1 0.61401 1