Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.042	0.251	0.37	5.0	-0.556	12.0	17.0
IHH	0.004	0.141	0.245	6.0	-0.462	4.0	10.0
SHH Np/Cholesterol/GAS1	-0.049	0.126	-9999.0	0.0	-0.264	18.0	18.0
LRPAP1	0.021	0.008	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.049	0.125	0.263	18.0	-9999.0	0.0	18.0
SMO/beta Arrestin2	-0.077	0.182	-9999.0	0.0	-0.417	7.0	7.0
SMO	-0.085	0.181	-9999.0	0.0	-0.434	7.0	7.0
AKT1	-0.041	0.132	-9999.0	0.0	-0.635	2.0	2.0
ARRB2	0.023	0.006	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.018	0.08	0.242	2.0	-0.424	2.0	4.0
ADRBK1	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.083	0.179	-9999.0	0.0	-0.428	7.0	7.0
STIL	-0.068	0.147	0.278	3.0	-0.327	6.0	9.0
DHH N/PTCH2	0.041	0.078	0.186	10.0	-0.306	2.0	12.0
DHH N/PTCH1	-0.01	0.14	0.321	1.0	-0.287	11.0	12.0
PIK3CA	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.035	0.103	0.242	9.0	-0.424	2.0	11.0
PTHLH	-0.099	0.353	0.705	1.0	-0.856	12.0	13.0
determination of left/right symmetry	-0.083	0.179	-9999.0	0.0	-0.428	7.0	7.0
PIK3R1	0.006	0.09	0.242	1.0	-0.424	3.0	4.0
skeletal system development	-0.097	0.349	0.704	1.0	-0.845	12.0	13.0
IHH N/Hhip	-0.025	0.167	0.219	5.0	-0.334	15.0	20.0
DHH N/Hhip	-0.002	0.146	0.2	11.0	-0.281	14.0	25.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.083	0.179	-9999.0	0.0	-0.428	7.0	7.0
pancreas development	-0.031	0.181	0.241	7.0	-0.423	12.0	19.0
HHAT	0.012	0.071	-9999.0	0.0	-0.424	2.0	2.0
PI3K	0.018	0.069	0.186	1.0	-0.306	3.0	4.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.003	0.114	0.242	1.0	-0.424	5.0	6.0
somite specification	-0.083	0.179	-9999.0	0.0	-0.428	7.0	7.0
SHH Np/Cholesterol/PTCH1	-0.061	0.15	0.315	2.0	-0.286	12.0	14.0
SHH Np/Cholesterol/PTCH2	-0.03	0.117	0.229	2.0	-0.246	15.0	17.0
SHH Np/Cholesterol/Megalin	-0.046	0.104	-9999.0	0.0	-0.242	15.0	15.0
SHH	-0.066	0.133	0.165	4.0	-0.317	15.0	19.0
catabolic process	-0.023	0.151	0.262	2.0	-0.322	13.0	15.0
SMO/Vitamin D3	-0.086	0.167	0.337	2.0	-0.402	5.0	7.0
SHH Np/Cholesterol/Hhip	-0.062	0.157	0.189	5.0	-0.275	23.0	28.0
LRP2	0.007	0.034	0.242	1.0	-9999.0	0.0	1.0
receptor-mediated endocytosis	-0.088	0.162	0.295	2.0	-0.385	6.0	8.0
SHH Np/Cholesterol/BOC	-0.037	0.115	0.152	1.0	-0.241	17.0	18.0
SHH Np/Cholesterol/CDO	-0.042	0.112	0.154	1.0	-0.237	18.0	19.0
mesenchymal cell differentiation	0.061	0.156	0.273	23.0	-0.187	5.0	28.0
mol:Vitamin D3	-0.056	0.16	0.329	3.0	-0.296	10.0	13.0
IHH N/PTCH2	0.025	0.094	0.219	2.0	-0.273	4.0	6.0
CDON	0.013	0.098	0.242	3.0	-0.424	3.0	6.0
IHH N/PTCH1	-0.007	0.167	0.331	3.0	-0.325	13.0	16.0
Megalin/LRPAP1	0.032	0.021	0.186	1.0	-9999.0	0.0	1.0
PTCH2	0.028	0.035	0.242	2.0	-9999.0	0.0	2.0
SHH Np/Cholesterol	-0.054	0.097	-9999.0	0.0	-0.241	15.0	15.0
PTCH1	-0.023	0.152	0.262	2.0	-0.323	13.0	15.0
HHIP	-0.031	0.181	0.242	7.0	-0.424	12.0	19.0