Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.033 0.133 0.41 26.0 -9999.0 0.0 26.0 KIRREL -0.037 0.166 -9999.0 0.0 -0.589 20.0 20.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.033 0.133 -9999.0 0.0 -0.41 26.0 26.0 PLCG1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.042 0.107 -9999.0 0.0 -0.343 20.0 20.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.001 0.093 -9999.0 0.0 -0.286 20.0 20.0 FYN -0.023 0.112 -9999.0 0.0 -0.333 21.0 21.0 mol:Ca2+ -0.042 0.106 -9999.0 0.0 -0.34 20.0 20.0 mol:DAG -0.042 0.107 -9999.0 0.0 -0.341 20.0 20.0 NPHS2 -0.022 0.106 -9999.0 0.0 -0.481 12.0 12.0 mol:IP3 -0.042 0.107 -9999.0 0.0 -0.341 20.0 20.0 regulation of endocytosis -0.013 0.105 -9999.0 0.0 -0.311 20.0 20.0 Nephrin/NEPH1/podocin/Cholesterol -0.043 0.11 -9999.0 0.0 -0.352 20.0 20.0 establishment of cell polarity -0.033 0.133 -9999.0 0.0 -0.41 26.0 26.0 Nephrin/NEPH1/podocin/NCK1-2 -0.031 0.099 -9999.0 0.0 -0.455 4.0 4.0 Nephrin/NEPH1/beta Arrestin2 -0.012 0.107 -9999.0 0.0 -0.314 20.0 20.0 NPHS1 -0.011 0.075 -9999.0 0.0 -0.464 6.0 6.0 Nephrin/NEPH1/podocin -0.023 0.112 -9999.0 0.0 -0.335 21.0 21.0 TJP1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.042 0.107 -9999.0 0.0 -0.343 20.0 20.0 CD2AP 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.042 0.107 -9999.0 0.0 -0.343 20.0 20.0 GRB2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.017 0.106 -9999.0 0.0 -0.313 20.0 20.0 cytoskeleton organization -0.0 0.109 -9999.0 0.0 -0.328 20.0 20.0 Nephrin/NEPH1 -0.021 0.095 -9999.0 0.0 -0.29 26.0 26.0 Nephrin/NEPH1/ZO-1 -0.035 0.1 -9999.0 0.0 -0.342 20.0 20.0