Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.119 0.204 -9999.0 0.0 -0.393 63.0 63.0 MAP3K8 0.017 0.043 -9999.0 0.0 -0.433 2.0 2.0 FOS -0.087 0.159 -9999.0 0.0 -0.38 37.0 37.0 PRKCA 0.012 0.022 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.009 0.056 0.261 3.0 -0.431 2.0 5.0 HRAS 0.024 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.11 0.2 -9999.0 0.0 -0.434 65.0 65.0 NRAS 0.025 0.002 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.029 0.032 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.044 0.125 -9999.0 0.0 -0.526 8.0 8.0 MAP2K1 -0.104 0.193 -9999.0 0.0 -0.396 67.0 67.0 ELK1 0.008 0.028 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.096 0.173 -9999.0 0.0 -0.371 65.0 65.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 73.0 73.0 MAPK1 -0.049 0.131 -9999.0 0.0 -0.517 10.0 10.0 RAF1 -0.092 0.173 0.21 1.0 -0.374 62.0 63.0 KRAS 0.025 0.018 0.289 1.0 -9999.0 0.0 1.0