Clinical Features Time to Death AGE NEOPLASM.DISEASESTAGE PATHOLOGY.T.STAGE PATHOLOGY.N.STAGE PATHOLOGY.M.STAGE GENDER HISTOLOGICAL.TYPE RADIATIONS.RADIATION.REGIMENINDICATION NUMBER.OF.LYMPH.NODES nMutated (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q PIK3CA 304 (32%) 645 0.31647 1 0.027965 1 0.77806 1 0.82718 1 0.85768 1 0.6501 1 1 1 0.0022034 1 0.87847 1 0.50346 1 CBFB 23 (2%) 926 0.87756 1 0.94672 1 0.78676 1 0.18292 1 0.081088 1 0.39283 1 0.19889 1 0.94508 1 1 1 0.44177 1 RUNX1 29 (3%) 920 0.83287 1 0.74614 1 0.56703 1 0.42116 1 0.36783 1 0.86289 1 1 1 0.0016138 1 0.67979 1 0.1749 1 GATA3 95 (10%) 854 0.3391 1 0.010428 1 0.33975 1 0.15406 1 0.45009 1 0.14238 1 1 1 0.042263 1 0.074785 1 0.0011562 0.814 FOXA1 22 (2%) 927 0.00057386 0.407 0.00058006 0.411 0.9203 1 0.31138 1 0.91943 1 0.54053 1 1 1 0.0088347 1 0.15224 1 0.4417 1 SF3B1 16 (2%) 933 0.30468 1 0.38087 1 0.41907 1 0.63573 1 0.83239 1 0.4327 1 1 1 0.94162 1 1 1 0.65378 1 MAP3K1 68 (7%) 881 0.92609 1 0.0055166 1 0.71669 1 0.45466 1 0.91169 1 0.358 1 1 1 0.77646 1 0.7815 1 0.017785 1 TP53 284 (30%) 665 0.11638 1 0.0050163 1 0.24619 1 0.022463 1 0.16111 1 0.056474 1 0.064494 1 2.3956e-12 1.74e-09 0.050915 1 0.86787 1 MAP2K4 32 (3%) 917 0.71486 1 0.39277 1 0.94627 1 0.29658 1 0.47545 1 0.58605 1 1 1 0.22805 1 0.69575 1 0.55632 1 PTEN 35 (4%) 914 0.97131 1 0.10661 1 0.060804 1 0.25165 1 0.52688 1 0.056897 1 1 1 0.1527 1 0.26099 1 0.43873 1 CDH1 96 (10%) 853 0.14548 1 0.011566 1 0.028042 1 1.2985e-06 0.000938 0.0074683 1 0.0048045 1 0.61012 1 1.5147e-69 1.1e-66 0.0090733 1 0.19414 1 TBX3 26 (3%) 923 0.33228 1 0.030169 1 0.60022 1 0.85905 1 0.60141 1 0.85009 1 1 1 0.2763 1 1 1 0.4966 1 MLL3 67 (7%) 882 0.20285 1 4.6257e-05 0.033 0.73545 1 0.63752 1 0.074587 1 0.55557 1 1 1 0.91194 1 0.57727 1 0.99201 1 RB1 19 (2%) 930 0.60047 1 0.15488 1 0.45883 1 0.34237 1 0.76894 1 0.40081 1 0.16706 1 0.89085 1 0.30609 1 0.47317 1 NCOR1 41 (4%) 908 0.65611 1 0.36256 1 0.93871 1 0.55722 1 0.94764 1 0.3095 1 1 1 0.65892 1 0.59949 1 0.46014 1 CTCF 17 (2%) 932 0.11777 1 0.62335 1 0.53226 1 0.18377 1 0.62226 1 1 1 1 1 0.4942 1 0.4212 1 0.033503 1 GPS2 11 (1%) 938 0.4567 1 0.13593 1 0.9927 1 0.10762 1 0.59192 1 1 1 1 1 0.61966 1 0.73864 1 0.55963 1 THEM5 11 (1%) 938 0.53405 1 0.20185 1 0.64317 1 0.03749 1 0.38591 1 1 1 1 1 0.0076634 1 0.73864 1 0.3674 1 RPGR 17 (2%) 932 0.48401 1 0.27999 1 0.90333 1 0.81694 1 0.20314 1 0.58748 1 1 1 0.98607 1 0.78984 1 0.0006504 0.459 DNAH12 17 (2%) 932 0.6714 1 0.53065 1 0.91594 1 0.71617 1 0.17978 1 1 1 1 1 0.63935 1 0.59238 1 0.28737 1 CDKN1B 9 (1%) 940 0.98729 1 0.9319 1 0.1833 1 0.033876 1 0.013774 1 0.068111 1 1 1 0.98205 1 1 1 0.1136 1 ZFP36L1 9 (1%) 940 0.38618 1 0.38104 1 0.95339 1 0.78658 1 0.89468 1 1 1 1 1 0.97245 1 0.46 1 0.054175 1 ASB10 8 (1%) 941 0.081266 1 0.50564 1 0.92948 1 0.76256 1 0.17449 1 1 1 1 1 0.1643 1 1 1 0.38017 1 HIST1H3B 10 (1%) 939 0.84621 1 0.053454 1 0.53148 1 0.55868 1 0.62231 1 1 1 1 1 0.95577 1 0.48724 1 0.46519 1 FAM86B1 8 (1%) 941 0.11215 1 0.085286 1 0.89048 1 0.90802 1 0.82428 1 0.34116 1 1 1 0.9136 1 0.44998 1 2.3003e-07 0.000166 PIK3R1 15 (2%) 934 0.010054 1 0.30164 1 0.42795 1 1 1 0.37499 1 0.30548 1 1 1 0.90868 1 1 1 0.00748 1 MYH9 19 (2%) 930 0.60079 1 0.42224 1 0.73027 1 0.8406 1 0.30662 1 0.63156 1 1 1 0.10387 1 0.078615 1 0.00061002 0.431 CASP8 10 (1%) 939 0.82525 1 0.57437 1 0.78725 1 0.92898 1 0.35546 1 1 1 1 1 0.62881 1 1 1 1.531e-06 0.0011 COL6A5 23 (2%) 926 0.35316 1 0.39994 1 0.99654 1 0.89944 1 0.9726 1 1 1 1 1 0.232 1 0.64177 1 0.68493 1 TBL1XR1 10 (1%) 939 0.88292 1 0.21818 1 0.37865 1 0.087892 1 0.029057 1 0.13085 1 1 1 0.87049 1 1 1 0.30919 1 ASXL2 16 (2%) 933 0.0068576 1 0.26382 1 0.82121 1 0.96409 1 0.13809 1 1 1 1 1 0.8868 1 1 1 0.00020325 0.145 ARID1A 27 (3%) 922 0.51427 1 0.89609 1 0.5887 1 0.35467 1 0.26895 1 1 1 1 1 0.7056 1 0.66747 1 0.9376 1 AQP12A 6 (1%) 943 0.5115 1 0.40111 1 0.99928 1 0.66941 1 0.24055 1 0.57563 1 1 1 0.88899 1 0.36398 1 0.92493 1 EPDR1 5 (1%) 944 0.50856 1 0.46333 1 0.80036 1 0.37426 1 0.24516 1 1 1 1 1 0.88332 1 0.63075 1 0.75998 1 ERBB2 21 (2%) 928 0.20366 1 0.11701 1 0.78351 1 0.18569 1 0.084116 1 1 1 0.18312 1 0.66425 1 0.46541 1 0.52965 1 MYB 12 (1%) 937 0.17341 1 0.1348 1 0.77563 1 0.41005 1 0.96471 1 0.50089 1 1 1 0.42875 1 0.3444 1 0.011531 1 TMEM151B 6 (1%) 943 0.55743 1 0.65873 1 0.61015 1 0.32755 1 0.5638 1 0.57563 1 1 1 0.94429 1 0.18956 1 0.00069321 0.489 GALNTL6 5 (1%) 944 0.46523 1 0.18936 1 0.99912 1 1 1 0.60609 1 1 1 1 1 0.94105 1 0.14926 1 0.25054 1 AKD1 18 (2%) 931 0.70875 1 0.15967 1 0.73596 1 0.79234 1 0.59277 1 0.60932 1 1 1 0.74828 1 0.30355 1 0.15391 1 AARS 9 (1%) 940 0.59157 1 0.29927 1 0.98332 1 0.12909 1 0.73106 1 0.66797 1 1 1 0.97245 1 0.72359 1 0.29795 1 HLA-C 9 (1%) 940 0.60734 1 0.16613 1 0.95673 1 0.22408 1 0.89468 1 0.39213 1 1 1 0.98205 1 0.72359 1 0.25637 1 GPRIN2 11 (1%) 938 0.93568 1 0.30405 1 0.93348 1 0.93533 1 0.33287 1 0.69499 1 1 1 0.33726 1 0.73864 1 0.19393 1 TRPM5 11 (1%) 938 0.62863 1 0.74716 1 0.42298 1 0.74232 1 0.70924 1 0.69499 1 0.0042102 1 0.011253 1 0.19188 1 4.8483e-06 0.00348 ANKRD12 17 (2%) 932 0.2854 1 0.17767 1 0.96272 1 0.58587 1 0.64711 1 0.35968 1 1 1 0.80865 1 0.4212 1 0.0003747 0.266 FBXW7 15 (2%) 934 0.71695 1 0.40712 1 0.70702 1 0.19341 1 0.63865 1 0.7655 1 1 1 0.87031 1 1 1 0.0016636 1 PRICKLE3 11 (1%) 938 0.90417 1 0.3032 1 0.062061 1 0.020693 1 0.9527 1 0.20614 1 1 1 0.85739 1 0.19188 1 0.00018857 0.134 WDR52 16 (2%) 933 0.34474 1 0.39293 1 0.6788 1 0.61579 1 0.19083 1 0.4327 1 0.14246 1 0.75649 1 1 1 9.2678e-08 6.71e-05 CDC42EP1 4 (0%) 945 0.39376 1 0.57619 1 0.0043696 1 1 1 0.43965 1 1 1 1 1 0.96586 1 1 1 0.30971 1 ERBB3 18 (2%) 931 2.2408e-05 0.016 0.08904 1 0.42905 1 0.063628 1 0.46876 1 1 1 1 1 0.85757 1 0.0028884 1 0.72911 1 FHOD3 13 (1%) 936 0.1431 1 0.078207 1 0.99711 1 0.4926 1 0.78034 1 0.72925 1 0.11721 1 0.80632 1 0.53829 1 0.053306 1 PTHLH 7 (1%) 942 0.51683 1 0.2545 1 0.83308 1 1 1 0.12854 1 1 1 1 1 0.99151 1 0.68017 1 1.1105e-41 8.08e-39 SHISA4 5 (1%) 944 0.47125 1 0.87185 1 0.99354 1 0.50541 1 0.52121 1 0.51026 1 1 1 0.99719 1 0.63075 1 0.15124 1 KCNN3 9 (1%) 940 0.16436 1 0.54852 1 0.81044 1 0.41655 1 0.51332 1 0.16263 1 1 1 0.59643 1 1 1 0.06878 1 FGFR2 10 (1%) 939 0.16321 1 0.38607 1 0.56127 1 0.014916 1 0.69696 1 0.44127 1 0.091305 1 0.85017 1 1 1 0.0018581 1 HLA-DRB5 6 (1%) 943 0.54433 1 0.22712 1 0.9786 1 0.66941 1 0.46751 1 1 1 1 1 0.94429 1 1 1 4.0208e-06 0.00289 ICOSLG 6 (1%) 943 0.47312 1 0.12615 1 0.62513 1 0.87991 1 0.73792 1 0.57563 1 1 1 0.94429 1 1 1 0.73495 1 GYG2 8 (1%) 941 0.59709 1 0.4493 1 0.42465 1 0.83288 1 0.78875 1 0.65965 1 1 1 0.95206 1 0.23903 1 4.3124e-06 0.0031 PPEF1 11 (1%) 938 0.038178 1 0.48907 1 0.99659 1 1 1 0.37061 1 1 1 1 1 0.9338 1 0.52548 1 0.077626 1 MAP4K1 10 (1%) 939 0.44898 1 0.94271 1 0.9305 1 0.52886 1 0.34095 1 1 1 1 1 0.95577 1 0.73241 1 0.52565 1 ZNF41 11 (1%) 938 0.48323 1 0.83927 1 0.93348 1 0.66658 1 0.57063 1 0.48817 1 1 1 0.97776 1 0.73864 1 0.39258 1 FBXO17 5 (1%) 944 0.0026424 1 0.63574 1 0.98126 1 0.50541 1 0.16305 1 0.18437 1 1 1 0.99719 1 1 1 0.61112 1 HRNR 31 (3%) 918 0.14618 1 0.26775 1 0.34453 1 0.12643 1 0.12553 1 0.75547 1 1 1 0.92618 1 0.23086 1 1.1496e-05 0.00822 STAG2 13 (1%) 936 0.016545 1 0.041973 1 0.83135 1 0.95138 1 0.92164 1 0.25395 1 1 1 0.59689 1 0.53829 1 0.73489 1 CEP57 4 (0%) 945 0.23049 1 0.20702 1 0.9511 1 0.52321 1 0.13856 1 0.43492 1 1 1 0.96586 1 0.58397 1 0.88026 1 SPRR2B 3 (0%) 946 0.71529 1 0.36931 1 0.99837 1 0.73134 1 1 1 1 1 1 1 0.98369 1 1 1 0.011464 1 ZFP36L2 7 (1%) 942 0.42844 1 0.9285 1 0.98368 1 0.90084 1 0.92768 1 1 1 1 1 0.99151 1 0.11236 1 0.006692 1 DMXL2 18 (2%) 931 0.72652 1 0.22049 1 0.36062 1 0.078087 1 0.061573 1 0.79209 1 0.15893 1 1.1455e-28 8.32e-26 0.30355 1 2.8127e-29 2.04e-26 ZBTB7C 5 (1%) 944 0.54051 1 0.68712 1 0.95753 1 1 1 0.16824 1 1 1 1 1 0.48646 1 0.32918 1 0.94558 1 MUC5B 32 (3%) 917 0.84942 1 0.82143 1 0.066049 1 0.54867 1 0.79803 1 0.40732 1 1 1 3.5322e-06 0.00254 1 1 0.93462 1 XBP1 4 (0%) 945 5.4706e-06 0.00392 0.026808 1 0.98615 1 0.79243 1 0.38122 1 1 1 1 1 0.74141 1 0.32953 1 NA NA FXYD5 4 (0%) 945 0.76672 1 0.93067 1 0.87159 1 0.14935 1 0.84242 1 1 1 1 1 0.74141 1 1 1 0.011464 1 ATXN2 15 (2%) 934 0.61393 1 0.12142 1 0.96503 1 0.57298 1 0.69229 1 1 1 1 1 0.98265 1 0.57327 1 0.55279 1 CCL13 4 (0%) 945 0.35077 1 0.1613 1 0.97854 1 0.64957 1 0.84242 1 1 1 1 1 0.74141 1 0.58397 1 0.011464 1