Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.095 0.2 0.643 110.0 -9999.0 0.0 110.0 KIRREL -0.084 0.25 -9999.0 0.0 -0.81 110.0 110.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.095 0.2 -9999.0 0.0 -0.644 110.0 110.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.069 0.152 -9999.0 0.0 -0.493 110.0 110.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.042 0.112 -9999.0 0.0 -0.365 110.0 110.0 FYN -0.064 0.146 -9999.0 0.0 -0.472 110.0 110.0 mol:Ca2+ -0.068 0.15 -9999.0 0.0 -0.488 110.0 110.0 mol:DAG -0.069 0.151 -9999.0 0.0 -0.49 110.0 110.0 NPHS2 -0.008 0.031 -9999.0 0.0 -0.286 5.0 5.0 mol:IP3 -0.069 0.151 -9999.0 0.0 -0.49 110.0 110.0 regulation of endocytosis -0.054 0.138 -9999.0 0.0 -0.44 110.0 110.0 Nephrin/NEPH1/podocin/Cholesterol -0.071 0.155 -9999.0 0.0 -0.501 110.0 110.0 establishment of cell polarity -0.095 0.2 -9999.0 0.0 -0.643 110.0 110.0 Nephrin/NEPH1/podocin/NCK1-2 -0.056 0.14 -9999.0 0.0 -0.449 110.0 110.0 Nephrin/NEPH1/beta Arrestin2 -0.055 0.14 -9999.0 0.0 -0.446 110.0 110.0 NPHS1 -0.051 0.108 -9999.0 0.0 -0.359 17.0 17.0 Nephrin/NEPH1/podocin -0.064 0.147 -9999.0 0.0 -0.475 110.0 110.0 TJP1 -0.001 0.025 -9999.0 0.0 -0.803 1.0 1.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.069 0.152 -9999.0 0.0 -0.493 110.0 110.0 CD2AP -0.0 0.009 -9999.0 0.0 -0.289 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 -0.069 0.152 -9999.0 0.0 -0.493 110.0 110.0 GRB2 -0.0 0.009 -9999.0 0.0 -0.289 1.0 1.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.073 0.17 -9999.0 0.0 -0.514 118.0 118.0 cytoskeleton organization -0.054 0.14 -9999.0 0.0 -0.457 110.0 110.0 Nephrin/NEPH1 -0.069 0.15 -9999.0 0.0 -0.484 110.0 110.0 Nephrin/NEPH1/ZO-1 -0.075 0.165 -9999.0 0.0 -0.533 110.0 110.0