Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.118 0.183 -9999.0 0.0 -0.521 60.0 60.0 MAP3K8 -0.006 0.067 -9999.0 0.0 -0.744 8.0 8.0 FOS -0.034 0.135 -9999.0 0.0 -0.465 35.0 35.0 PRKCA -0.013 0.131 -9999.0 0.0 -0.778 29.0 29.0 PTPN7 -0.008 0.071 -9999.0 0.0 -0.326 18.0 18.0 HRAS -0.003 0.027 -9999.0 0.0 -0.291 9.0 9.0 PRKCB -0.011 0.114 -9999.0 0.0 -0.553 36.0 36.0 NRAS -0.001 0.013 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP -0.002 0.015 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.007 0.073 -9999.0 0.0 -9999.0 0.0 0.0 MAP2K1 -0.012 0.136 -9999.0 0.0 -0.601 44.0 44.0 ELK1 -0.003 0.005 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.032 0.116 -9999.0 0.0 -0.573 44.0 44.0 mol:GTP -0.002 0.003 -9999.0 0.0 -0.006 307.0 307.0 MAPK1 -0.007 0.073 -9999.0 0.0 -0.291 1.0 1.0 RAF1 -0.032 0.116 -9999.0 0.0 -0.573 44.0 44.0 KRAS -0.001 0.013 -9999.0 0.0 -0.289 2.0 2.0