Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.041	0.223	0.435	4.0	-0.633	108.0	112.0
IHH	0.016	0.082	0.268	30.0	-0.232	15.0	45.0
SHH Np/Cholesterol/GAS1	0.001	0.075	-9999.0	0.0	-0.335	44.0	44.0
LRPAP1	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	-0.001	0.074	0.332	44.0	-9999.0	0.0	44.0
SMO/beta Arrestin2	-0.019	0.208	-9999.0	0.0	-0.629	88.0	88.0
SMO	-0.042	0.211	0.324	1.0	-0.655	91.0	92.0
AKT1	-0.003	0.129	-9999.0	0.0	-0.61	20.0	20.0
ARRB2	0.022	0.007	-9999.0	0.0	-9999.0	0.0	0.0
BOC	-0.019	0.155	-9999.0	0.0	-0.576	73.0	73.0
ADRBK1	0.023	0.006	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.041	0.207	0.323	1.0	-0.642	91.0	92.0
STIL	0.008	0.174	0.304	27.0	-0.485	81.0	108.0
DHH N/PTCH2	-0.012	0.145	-9999.0	0.0	-0.445	99.0	99.0
DHH N/PTCH1	-0.027	0.205	-9999.0	0.0	-0.552	114.0	114.0
PIK3CA	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.008	0.099	0.26	2.0	-0.576	28.0	30.0
PTHLH	-0.061	0.299	0.525	2.0	-0.835	113.0	115.0
determination of left/right symmetry	-0.041	0.207	0.323	1.0	-0.642	91.0	92.0
PIK3R1	0.018	0.056	-9999.0	0.0	-0.576	9.0	9.0
skeletal system development	-0.06	0.294	0.524	2.0	-0.823	113.0	115.0
IHH N/Hhip	0.028	0.056	0.257	1.0	-0.467	1.0	2.0
DHH N/Hhip	0.023	0.078	-9999.0	0.0	-0.422	29.0	29.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.041	0.207	0.323	1.0	-0.642	91.0	92.0
pancreas development	0.024	0.028	0.259	8.0	-0.575	1.0	9.0
HHAT	0.02	0.021	-9999.0	0.0	-0.576	1.0	1.0
PI3K	0.029	0.043	-9999.0	0.0	-0.402	9.0	9.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.007	0.132	-9999.0	0.0	-0.576	52.0	52.0
somite specification	-0.041	0.207	0.323	1.0	-0.642	91.0	92.0
SHH Np/Cholesterol/PTCH1	-0.024	0.16	0.3	1.0	-0.497	87.0	88.0
SHH Np/Cholesterol/PTCH2	-0.006	0.087	-9999.0	0.0	-0.336	61.0	61.0
SHH Np/Cholesterol/Megalin	-0.059	0.149	0.28	3.0	-0.336	211.0	214.0
SHH	-0.0	0.038	0.345	7.0	-0.431	1.0	8.0
catabolic process	-0.032	0.207	0.318	2.0	-0.573	115.0	117.0
SMO/Vitamin D3	-0.008	0.198	0.367	14.0	-0.573	85.0	99.0
SHH Np/Cholesterol/Hhip	0.016	0.03	0.28	5.0	-0.34	2.0	7.0
LRP2	-0.122	0.266	0.26	25.0	-0.576	257.0	282.0
receptor-mediated endocytosis	-0.079	0.221	0.307	10.0	-0.628	96.0	106.0
SHH Np/Cholesterol/BOC	-0.005	0.086	-9999.0	0.0	-0.336	59.0	59.0
SHH Np/Cholesterol/CDO	0.013	0.042	-9999.0	0.0	-0.337	12.0	12.0
mesenchymal cell differentiation	-0.016	0.03	0.338	2.0	-0.277	5.0	7.0
mol:Vitamin D3	0.003	0.182	0.35	19.0	-0.509	83.0	102.0
IHH N/PTCH2	-0.009	0.143	-9999.0	0.0	-0.471	79.0	79.0
CDON	0.015	0.065	-9999.0	0.0	-0.576	12.0	12.0
IHH N/PTCH1	-0.023	0.213	0.357	4.0	-0.577	115.0	119.0
Megalin/LRPAP1	-0.079	0.204	-9999.0	0.0	-0.423	260.0	260.0
PTCH2	-0.021	0.159	-9999.0	0.0	-0.576	77.0	77.0
SHH Np/Cholesterol	0.01	0.014	-9999.0	0.0	-0.336	1.0	1.0
PTCH1	-0.032	0.208	0.319	2.0	-0.576	115.0	117.0
HHIP	0.024	0.029	0.26	8.0	-0.576	1.0	9.0