Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.054 0.202 0.315 1.0 -0.524 61.0 62.0 MAP3K8 0.01 0.049 -9999.0 0.0 -0.58 6.0 6.0 FOS -0.019 0.142 0.319 2.0 -0.465 43.0 45.0 PRKCA -0.002 0.087 0.239 1.0 -0.584 21.0 22.0 PTPN7 0.021 0.059 0.261 38.0 -9999.0 0.0 38.0 HRAS 0.024 0.022 0.259 8.0 -9999.0 0.0 8.0 PRKCB 0.006 0.08 0.252 18.0 -0.584 14.0 32.0 NRAS 0.023 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.026 0.036 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.008 0.091 -9999.0 0.0 -0.801 5.0 5.0 MAP2K1 -0.011 0.119 -9999.0 0.0 -0.514 40.0 40.0 ELK1 0.007 0.029 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.012 0.099 -9999.0 0.0 -0.489 36.0 36.0 mol:GTP -0.002 0.003 -9999.0 0.0 -0.006 301.0 301.0 MAPK1 -0.007 0.121 -9999.0 0.0 -0.546 24.0 24.0 RAF1 -0.011 0.098 -9999.0 0.0 -0.484 36.0 36.0 KRAS 0.023 0.005 -9999.0 0.0 -9999.0 0.0 0.0