		Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
amp_1p31.3	62 (32%)	130	0.68299	1	0.19671	1	0.13821	1	0.098398	1	0.97058	1	0.15555	1	0.94257	1	0.49209	1
amp_1q21.3	98 (51%)	94	0.0056864	1	0.30857	1	0.36688	1	0.27592	1	0.7818	1	0.47454	1	0.85678	1	0.34563	1
amp_2p24.3	50 (26%)	142	0.018278	1	0.017257	1	0.41033	1	0.047482	1	0.1698	1	0.00089927	0.36	0.32966	1	0.013044	1
amp_2q33.1	30 (16%)	162	0.0032579	1	0.05967	1	0.00014453	0.0607	0.058379	1	0.25391	1	0.0082156	1	0.09651	1	0.15499	1
amp_3q26.31	148 (77%)	44	2.633e-09	1.16e-06	0.00081263	0.329	0.016975	1	0.00058366	0.238	0.03547	1	0.0046436	1	0.05147	1	0.00022498	0.0938
amp_3q28	148 (77%)	44	2.633e-09	1.16e-06	0.0030453	1	0.044561	1	0.00084018	0.339	0.02249	1	0.002507	0.955	0.038834	1	0.00013341	0.0562
amp_5p15.33	80 (42%)	112	1.4084e-07	6.14e-05	0.025703	1	0.11405	1	0.016368	1	0.016368	1	0.011035	1	0.025506	1	0.052554	1
amp_6p21.33	51 (27%)	141	0.05022	1	0.0043599	1	0.050276	1	0.011656	1	0.21498	1	0.050545	1	0.41605	1	0.55375	1
amp_7p11.2	34 (18%)	158	3.8171e-05	0.0163	0.020566	1	0.025583	1	0.049187	1	0.0089309	1	0.015749	1	0.0074703	1	0.039804	1
amp_8q24.21	79 (41%)	113	0.25427	1	0.69357	1	0.86801	1	0.96133	1	0.013106	1	0.30175	1	0.10082	1	0.23905	1
amp_9p24.1	41 (21%)	151	0.22504	1	0.057754	1	0.64707	1	0.0088389	1	0.44507	1	0.18474	1	0.82759	1	0.18242	1
amp_11p13	16 (8%)	176	0.24073	1	0.58667	1	0.34746	1	0.91956	1	0.57828	1	0.46301	1	0.77258	1	0.47683	1
amp_11q13.3	24 (12%)	168	0.0031354	1	0.0040275	1	0.0072774	1	0.0071508	1	0.017832	1	0.0053648	1	0.016233	1	0.024771	1
amp_11q22.1	33 (17%)	159	5.9406e-05	0.0252	1.6889e-05	0.0073	0.00028407	0.117	0.00010318	0.0435	0.016512	1	0.01665	1	0.013174	1	0.0079745	1
amp_13q22.1	41 (21%)	151	0.010972	1	0.13953	1	0.14829	1	0.93394	1	0.67381	1	0.52385	1	0.68724	1	0.30568	1
amp_13q34	43 (22%)	149	0.0029454	1	0.8072	1	0.93398	1	0.93394	1	0.72368	1	0.15374	1	0.61015	1	0.081508	1
amp_15q26.1	46 (24%)	146	0.96432	1	0.43334	1	0.76088	1	0.39117	1	0.28611	1	1	1	0.18868	1	0.78728	1
amp_16p13.13	39 (20%)	153	0.19262	1	0.48133	1	0.35781	1	0.31364	1	0.25652	1	0.42731	1	0.49234	1	0.30965	1
amp_17q12	36 (19%)	156	0.03169	1	0.045913	1	0.15744	1	0.13581	1	0.17515	1	0.077863	1	0.16262	1	0.17809	1
amp_17q25.1	53 (28%)	139	0.00017291	0.0725	0.019318	1	0.098405	1	0.17656	1	0.051134	1	0.60232	1	0.028455	1	0.65009	1
amp_19q13.2	59 (31%)	133	7.2753e-07	0.000316	0.065678	1	0.40195	1	0.52836	1	0.44693	1	0.4352	1	0.19474	1	0.7395	1
amp_20q11.21	87 (45%)	105	0.00025979	0.108	0.14956	1	0.15612	1	0.24235	1	0.88751	1	0.3188	1	0.44142	1	0.27337	1
amp_xq28	47 (24%)	145	0.7825	1	0.99182	1	0.75268	1	0.5809	1	0.0047879	1	0.036801	1	0.030843	1	0.081163	1
del_1p36.31	26 (14%)	166	0.031356	1	0.10599	1	0.042473	1	0.0010943	0.431	0.05525	1	8.1765e-05	0.0347	0.01275	1	0.0016568	0.641
del_2q22.1	37 (19%)	155	0.79185	1	0.91457	1	0.38313	1	0.27852	1	0.72985	1	0.76144	1	0.86207	1	0.73126	1
del_2q37.1	81 (42%)	111	0.17182	1	0.008241	1	0.0083262	1	0.00073617	0.299	0.018272	1	0.007129	1	0.014383	1	0.0029137	1
del_3p14.2	78 (41%)	114	1.1037e-05	0.00479	0.00090075	0.36	0.020022	1	0.0021138	0.814	0.005262	1	0.006427	1	0.011537	1	0.00085443	0.343
del_4q21.3	58 (30%)	134	7.7326e-08	3.38e-05	0.011451	1	0.58122	1	0.0038265	1	0.317	1	0.65164	1	0.76245	1	0.43595	1
del_4q35.2	70 (36%)	122	3.8972e-08	1.71e-05	0.07629	1	0.094557	1	0.0017447	0.673	0.35347	1	0.44819	1	0.96959	1	0.68141	1
del_5q13.3	47 (24%)	145	2.4242e-05	0.0104	0.037641	1	0.32416	1	0.37983	1	0.052426	1	0.47603	1	0.089702	1	0.39236	1
del_5q35.2	49 (26%)	143	1.8791e-05	0.0081	0.063249	1	0.65443	1	0.87857	1	0.042593	1	0.28946	1	0.082923	1	0.35992	1
del_6p24.2	29 (15%)	163	0.55568	1	0.093177	1	0.24441	1	0.52292	1	0.19626	1	0.83329	1	0.86526	1	0.55637	1
del_6q26	65 (34%)	127	0.0098242	1	0.41891	1	0.74574	1	0.63898	1	0.60164	1	0.22698	1	0.70469	1	0.22532	1
del_7q34	43 (22%)	149	0.0050479	1	0.96477	1	0.68288	1	0.69608	1	0.45347	1	0.52752	1	0.60324	1	0.67634	1
del_8p23.3	66 (34%)	126	0.0034396	1	0.13599	1	0.091525	1	0.85093	1	0.83096	1	0.1573	1	0.82889	1	0.27316	1
del_10q23.31	55 (29%)	137	0.031368	1	0.19736	1	0.2418	1	0.65012	1	0.66863	1	1	1	0.97258	1	1	1
del_11p15.1	62 (32%)	130	0.01465	1	0.046014	1	0.059603	1	0.037164	1	0.18716	1	0.082059	1	0.16818	1	0.061458	1
del_11q25	107 (56%)	85	4.3693e-05	0.0186	0.1802	1	0.32281	1	0.028857	1	0.087609	1	0.032703	1	0.039539	1	0.0079416	1
del_13q12.12	68 (35%)	124	0.00086563	0.347	0.014253	1	0.16665	1	0.0030824	1	0.010783	1	0.021007	1	0.010604	1	0.01478	1
del_13q14.2	74 (39%)	118	0.0023075	0.884	0.0085314	1	0.067872	1	0.0014742	0.573	0.0035366	1	0.0027593	1	0.0028618	1	0.0066964	1
del_14q32.31	31 (16%)	161	0.0057434	1	0.26163	1	0.0089346	1	0.0002717	0.112	0.038133	1	0.036928	1	0.00054012	0.221	0.036105	1
del_15q21.1	38 (20%)	154	0.018512	1	0.05259	1	0.4142	1	0.21336	1	0.27015	1	0.0232	1	0.12412	1	0.1132	1
del_16q12.1	39 (20%)	153	0.57456	1	0.017487	1	0.1731	1	0.34717	1	0.14572	1	0.078676	1	0.010226	1	0.1541	1
del_16q23.1	39 (20%)	153	0.51074	1	0.00093067	0.37	0.0039763	1	0.003877	1	0.054993	1	0.0016054	0.623	0.0010649	0.421	0.0047369	1
del_17p12	61 (32%)	131	0.0033196	1	0.44218	1	0.21679	1	0.11011	1	0.035694	1	0.37507	1	0.063655	1	0.095922	1
del_17q25.3	32 (17%)	160	0.3947	1	0.00021437	0.0896	1.9311e-05	0.0083	0.0026533	1	1.5143e-05	0.00656	0.0012011	0.472	2.9336e-05	0.0126	0.00023734	0.0987
del_18q21.2	53 (28%)	139	0.015816	1	0.0014076	0.55	9.612e-05	0.0407	0.00058295	0.238	0.063747	1	0.00027349	0.113	0.0013596	0.533	0.0096585	1
del_19p13.3	58 (30%)	134	0.0041163	1	0.00064627	0.263	0.0028585	1	0.0065056	1	0.43346	1	0.00051943	0.213	0.2503	1	0.019371	1
del_19q13.33	22 (11%)	170	0.24364	1	0.24059	1	0.1018	1	0.48657	1	0.46733	1	0.10911	1	0.48762	1	0.17137	1
del_20p12.1	25 (13%)	167	0.80183	1	0.44577	1	0.27113	1	0.74965	1	0.33363	1	0.16001	1	0.23552	1	0.73191	1
del_21q21.1	35 (18%)	157	0.038287	1	0.38726	1	0.84835	1	0.0023653	0.904	0.75564	1	0.67058	1	0.92894	1	0.74375	1
del_22q13.32	52 (27%)	140	0.16554	1	0.12966	1	0.25717	1	0.38485	1	0.88567	1	0.20337	1	0.54049	1	0.36457	1
del_xp21.1	42 (22%)	150	0.001042	0.414	0.090689	1	0.13142	1	0.28574	1	0.012415	1	0.017116	1	0.010355	1	0.002768	1
del_xp11.3	46 (24%)	146	0.0014069	0.55	0.068849	1	0.086545	1	0.13856	1	0.00106	0.42	0.010267	1	0.00082367	0.333	0.0021421	0.823
del_xq21.33	39 (20%)	153	0.062963	1	0.025319	1	0.30341	1	0.025813	1	0.073328	1	0.012852	1	0.1495	1	0.0071511	1
