Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
amp_1p34.2	20 (19%)	83	0.22785	1	0.090834	1	0.80833	1	0.88329	1	0.78275	1	0.58714	1	0.80294	1	0.58714	1
amp_1q21.3	52 (50%)	51	0.004012	1	0.49357	1	1	1	0.85916	1	0.93034	1	0.5522	1	0.85364	1	0.5522	1
amp_2q14.2	34 (33%)	69	0.5448	1	1	1	0.58116	1	0.3779	1	0.42172	1	0.77625	1	0.44564	1	0.77625	1
amp_3q26.2	70 (68%)	33	1.4938e-10	8.48e-08	4.307e-05	0.024	0.0016324	0.867	8.5725e-06	0.00482	7.1999e-06	0.00405	3.2005e-07	0.000181	7.6297e-05	0.0424	3.2005e-07	0.000181
amp_5p15.33	59 (57%)	44	0.0017247	0.911	0.032877	1	0.051697	1	0.0024426	1	0.012404	1	0.0061257	1	0.046479	1	0.0061257	1
amp_6p21.1	35 (34%)	68	0.0040121	1	0.52486	1	0.27603	1	0.28682	1	0.43469	1	0.45953	1	0.36034	1	0.45953	1
amp_7p22.3	70 (68%)	33	0.15369	1	0.5899	1	0.0014933	0.796	0.0088257	1	0.38933	1	0.39396	1	0.86397	1	0.39396	1
amp_7p11.2	70 (68%)	33	0.5065	1	0.43543	1	0.042707	1	0.3027	1	0.10282	1	0.2353	1	0.2869	1	0.2353	1
amp_7q21.2	66 (64%)	37	0.06705	1	0.14575	1	0.94983	1	1	1	0.30433	1	0.41792	1	0.66941	1	0.41792	1
amp_8p11.21	49 (48%)	54	0.21411	1	0.77603	1	0.23635	1	1	1	0.904	1	0.68059	1	0.71916	1	0.68059	1
amp_8q24.21	83 (81%)	20	0.0021122	1	0.0129	1	0.16942	1	0.035003	1	0.30611	1	0.023701	1	0.024018	1	0.023701	1
amp_9p13.3	22 (21%)	81	0.43958	1	0.31165	1	0.33454	1	0.59271	1	0.12139	1	0.59892	1	0.85242	1	0.59892	1
amp_10p11.21	29 (28%)	74	0.70343	1	0.17974	1	0.92184	1	0.86229	1	0.92426	1	0.80182	1	0.89826	1	0.80182	1
amp_11p13	28 (27%)	75	0.72973	1	0.86314	1	0.24265	1	0.71968	1	0.53544	1	0.46274	1	0.49157	1	0.46274	1
amp_11q13.3	57 (55%)	46	0.0021435	1	0.050656	1	0.18094	1	0.064437	1	0.10372	1	0.020778	1	0.17257	1	0.020778	1
amp_12p13.33	42 (41%)	61	1.5173e-05	0.00848	0.028563	1	0.035902	1	0.0096341	1	0.012879	1	0.0093151	1	0.11479	1	0.0093151	1
amp_12p12.1	48 (47%)	55	2.0794e-05	0.0116	0.13638	1	0.33602	1	0.057612	1	0.02071	1	0.030716	1	0.066674	1	0.030716	1
amp_13q22.1	36 (35%)	67	0.052173	1	0.23157	1	0.29888	1	0.10415	1	0.031051	1	0.064359	1	0.084174	1	0.064359	1
amp_15q26.3	33 (32%)	70	0.24912	1	0.027875	1	0.29939	1	0.088793	1	0.12613	1	0.079279	1	0.12371	1	0.079279	1
amp_17q12	38 (37%)	65	0.0014229	0.76	0.1912	1	0.33888	1	0.024005	1	0.047493	1	0.10114	1	0.16969	1	0.10114	1
amp_18p11.32	37 (36%)	66	0.0047727	1	0.5464	1	0.77752	1	0.5046	1	0.66208	1	0.63394	1	0.46153	1	0.63394	1
amp_18q11.2	31 (30%)	72	0.52167	1	0.03747	1	0.34478	1	0.14901	1	0.28332	1	0.20776	1	0.53149	1	0.20776	1
amp_19p13.2	18 (17%)	85	0.10607	1	0.20402	1	0.21899	1	0.27167	1	0.05077	1	0.30073	1	0.036602	1	0.30073	1
amp_19q12	29 (28%)	74	0.0010368	0.558	0.17748	1	0.42728	1	0.25818	1	0.28332	1	0.20776	1	0.046087	1	0.20776	1
del_1p36.13	33 (32%)	70	0.048706	1	0.093143	1	0.316	1	0.19242	1	0.3736	1	0.319	1	0.67028	1	0.319	1
del_1p13.2	34 (33%)	69	0.046137	1	0.62821	1	0.25461	1	0.36467	1	0.8357	1	0.79488	1	0.68819	1	0.79488	1
del_1q44	13 (13%)	90	0.21893	1	0.82426	1	0.26197	1	0.5943	1	0.46594	1	0.39067	1	0.70372	1	0.39067	1
del_2q22.1	32 (31%)	71	0.092779	1	0.007204	1	0.39511	1	0.18727	1	0.082926	1	0.057836	1	0.079597	1	0.057836	1
del_2q33.3	17 (17%)	86	1	1	0.025466	1	0.26076	1	0.4905	1	0.1279	1	0.45111	1	0.30979	1	0.45111	1
del_3p14.3	71 (69%)	32	0.00014174	0.0782	0.0016727	0.887	0.021974	1	0.00014243	0.0785	0.00022214	0.122	1.2313e-05	0.00691	0.0020691	1	1.2313e-05	0.00691
del_3p14.2	72 (70%)	31	0.0017434	0.919	0.01735	1	0.30869	1	0.0062927	1	0.018661	1	0.0010074	0.544	0.051112	1	0.0010074	0.544
del_3q11.1	17 (17%)	86	0.77414	1	0.88655	1	0.45984	1	0.5232	1	0.69859	1	0.58344	1	0.70221	1	0.58344	1
del_3q26.31	8 (8%)	95	0.053387	1	0.073265	1	0.068035	1	0.020513	1	0.044336	1	0.019064	1	0.084261	1	0.019064	1
del_4p16.3	53 (51%)	50	0.70205	1	0.71763	1	0.36174	1	0.809	1	0.19299	1	0.41624	1	0.26662	1	0.41624	1
del_4p15.2	54 (52%)	49	0.018474	1	0.39921	1	0.16979	1	0.53674	1	0.14429	1	0.23339	1	0.6636	1	0.23339	1
del_4q21.23	50 (49%)	53	0.00074633	0.406	0.17125	1	0.052398	1	0.48918	1	0.32078	1	0.69424	1	0.71396	1	0.69424	1
del_4q22.1	53 (51%)	50	0.00047195	0.259	0.248	1	0.033287	1	0.49991	1	0.31883	1	0.61524	1	0.66427	1	0.61524	1
del_5q11.2	58 (56%)	45	0.07168	1	0.028321	1	0.69773	1	0.69776	1	0.88728	1	0.68421	1	0.41175	1	0.68421	1
del_6p25.3	37 (36%)	66	0.7745	1	0.15399	1	0.66143	1	0.48306	1	0.30107	1	0.2707	1	0.1612	1	0.2707	1
del_6q16.1	29 (28%)	74	0.31157	1	0.60009	1	0.3548	1	0.47808	1	0.92983	1	1	1	0.84739	1	1	1
del_6q26	25 (24%)	78	0.10135	1	0.3842	1	0.074088	1	0.048933	1	0.15825	1	0.096171	1	0.31171	1	0.096171	1
del_7q31.1	30 (29%)	73	0.75986	1	0.58865	1	0.31782	1	0.62703	1	0.8997	1	0.80105	1	0.66754	1	0.80105	1
del_7q36.2	38 (37%)	65	0.8467	1	0.60019	1	0.13954	1	0.90076	1	0.17964	1	0.75624	1	0.31941	1	0.75624	1
del_8p23.2	46 (45%)	57	0.0039938	1	0.52178	1	0.04019	1	0.22083	1	0.18528	1	0.068963	1	0.13143	1	0.068963	1
del_9p21.3	78 (76%)	25	2.037e-06	0.00115	0.10349	1	0.044957	1	0.00096851	0.524	0.0077381	1	0.00010972	0.0609	0.00095349	0.517	0.00010972	0.0609
del_10p15.1	28 (27%)	75	0.22163	1	0.5647	1	0.51998	1	0.16781	1	0.6142	1	0.57656	1	0.57782	1	0.57656	1
del_10p11.21	23 (22%)	80	0.0019074	1	0.0014973	0.797	0.10884	1	0.019986	1	0.017016	1	0.020566	1	0.041303	1	0.020566	1
del_10q22.3	33 (32%)	70	0.0083352	1	0.0075105	1	0.203	1	0.030664	1	0.14271	1	0.058474	1	0.15147	1	0.058474	1
del_10q23.31	41 (40%)	62	0.032538	1	0.14485	1	0.52762	1	0.75345	1	0.79375	1	0.83586	1	0.88634	1	0.83586	1
del_11p15.4	39 (38%)	64	0.3611	1	0.28924	1	0.077536	1	0.1069	1	0.12035	1	0.046314	1	0.085777	1	0.046314	1
del_11q24.3	43 (42%)	60	0.0030099	1	0.4704	1	0.66465	1	0.46247	1	0.59198	1	0.28749	1	0.18732	1	0.28749	1
del_12q23.1	27 (26%)	76	0.65189	1	0.49695	1	0.18097	1	0.1083	1	0.16675	1	0.20776	1	0.43497	1	0.20776	1
del_13q14.2	46 (45%)	57	0.00048475	0.265	0.0068135	1	0.026104	1	0.018155	1	0.01619	1	0.0037096	1	0.004153	1	0.0037096	1
del_13q21.2	42 (41%)	61	0.0014185	0.759	0.19371	1	0.32183	1	0.15691	1	0.12035	1	0.046314	1	0.020352	1	0.046314	1
del_15q11.2	33 (32%)	70	0.21808	1	0.40389	1	0.78429	1	0.5353	1	0.66471	1	0.67996	1	0.46153	1	0.67996	1
del_16p13.3	30 (29%)	73	0.00013515	0.0747	0.0022777	1	0.072814	1	0.022954	1	0.066908	1	0.062096	1	0.12919	1	0.062096	1
del_16q23.1	45 (44%)	58	2.4958e-06	0.00141	0.0003899	0.214	0.0013962	0.748	0.00082975	0.451	0.0017045	0.902	0.00073683	0.402	0.015374	1	0.00073683	0.402
del_17p11.2	45 (44%)	58	0.10309	1	0.0013008	0.699	0.0081825	1	0.0033337	1	0.0073188	1	0.0040605	1	0.0031964	1	0.0040605	1
del_17q24.3	14 (14%)	89	0.61561	1	0.65752	1	0.82272	1	0.28167	1	0.79386	1	0.73653	1	0.34013	1	0.73653	1
del_17q25.3	25 (24%)	78	0.24021	1	0.92403	1	0.17132	1	0.57732	1	0.53515	1	0.76018	1	0.26587	1	0.76018	1
del_18q12.2	55 (53%)	48	0.30741	1	0.13609	1	0.11148	1	0.066749	1	0.087315	1	0.074276	1	0.04725	1	0.074276	1
del_18q21.2	61 (59%)	42	0.63536	1	0.086617	1	0.28899	1	0.10886	1	0.3585	1	0.18111	1	0.13469	1	0.18111	1
del_19p13.3	46 (45%)	57	0.049069	1	0.92672	1	0.70488	1	0.81494	1	0.20208	1	0.79034	1	0.44053	1	0.79034	1
del_19q13.31	28 (27%)	75	0.057227	1	0.043028	1	0.3271	1	0.18306	1	0.086089	1	0.13659	1	0.39784	1	0.13659	1
del_20p12.1	19 (18%)	84	0.074589	1	0.83528	1	0.57852	1	0.31666	1	0.1584	1	0.42626	1	0.21385	1	0.42626	1
del_21q11.2	61 (59%)	42	0.67584	1	0.39626	1	0.30759	1	0.017203	1	0.56683	1	0.22786	1	0.47153	1	0.22786	1
del_21q22.12	57 (55%)	46	0.45899	1	0.058337	1	0.016741	1	0.0099136	1	0.12895	1	0.051623	1	0.073521	1	0.051623	1
del_22q12.3	38 (37%)	65	0.013296	1	0.0036098	1	0.034618	1	0.062038	1	0.12312	1	0.065601	1	0.1635	1	0.065601	1
del_xp21.1	40 (39%)	63	0.0052219	1	0.03708	1	0.046934	1	0.11206	1	0.6836	1	0.37527	1	0.76905	1	0.37527	1
del_xp11.3	42 (41%)	61	0.0018113	0.953	0.026692	1	0.061119	1	0.008325	1	0.10489	1	0.035339	1	0.21266	1	0.035339	1
del_xq21.33	23 (22%)	80	0.59099	1	0.59463	1	0.51622	1	0.75467	1	0.79413	1	0.72409	1	1	1	0.72409	1