Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.045 0.117 0.38 2.0 -0.551 10.0 12.0 MAP3K8 0.027 0.039 -9999.0 0.0 -0.587 2.0 2.0 FOS 0.031 0.104 0.356 4.0 -0.529 8.0 12.0 PRKCA 0.03 0.008 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 -0.01 0.152 -9999.0 0.0 -0.588 33.0 33.0 HRAS 0.029 0.027 -9999.0 0.0 -0.587 1.0 1.0 PRKCB 0.023 0.064 -9999.0 0.0 -0.615 5.0 5.0 NRAS 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.055 0.024 -9999.0 0.0 -0.333 1.0 1.0 MAPK3 0.019 0.088 -9999.0 0.0 -0.547 7.0 7.0 MAP2K1 0.029 0.054 -9999.0 0.0 -0.489 2.0 2.0 ELK1 0.03 0.009 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.029 0.04 -9999.0 0.0 -0.446 2.0 2.0 mol:GTP 0.0 0.002 -9999.0 0.0 -0.007 13.0 13.0 MAPK1 0.018 0.09 -9999.0 0.0 -0.485 9.0 9.0 RAF1 0.021 0.041 -9999.0 0.0 -0.446 2.0 2.0 KRAS 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0