Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.502 0.352 0.726 135.0 -9999.0 0.0 135.0 KIRREL -0.126 0.247 -9999.0 0.0 -0.875 19.0 19.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.504 0.353 -9999.0 0.0 -0.728 135.0 135.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.011 0.021 -9999.0 0.0 -0.284 1.0 1.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.552 0.378 -9999.0 0.0 -0.719 152.0 152.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.42 0.311 -9999.0 0.0 -0.554 152.0 152.0 FYN -0.518 0.363 -9999.0 0.0 -0.68 152.0 152.0 mol:Ca2+ -0.543 0.37 -9999.0 0.0 -0.707 152.0 152.0 mol:DAG -0.547 0.374 -9999.0 0.0 -0.713 152.0 152.0 NPHS2 -0.388 0.409 -9999.0 0.0 -0.872 82.0 82.0 mol:IP3 -0.547 0.374 -9999.0 0.0 -0.713 152.0 152.0 regulation of endocytosis -0.485 0.343 -9999.0 0.0 -0.638 152.0 152.0 Nephrin/NEPH1/podocin/Cholesterol -0.557 0.38 -9999.0 0.0 -0.726 152.0 152.0 establishment of cell polarity -0.502 0.352 -9999.0 0.0 -0.726 135.0 135.0 Nephrin/NEPH1/podocin/NCK1-2 -0.513 0.357 -9999.0 0.0 -0.669 152.0 152.0 Nephrin/NEPH1/beta Arrestin2 -0.496 0.353 -9999.0 0.0 -0.651 152.0 152.0 NPHS1 -0.569 0.398 -9999.0 0.0 -0.855 130.0 130.0 Nephrin/NEPH1/podocin -0.526 0.364 -9999.0 0.0 -0.686 152.0 152.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.552 0.378 -9999.0 0.0 -0.719 152.0 152.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.552 0.378 -9999.0 0.0 -0.719 152.0 152.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.619 0.406 -9999.0 0.0 -0.765 161.0 161.0 cytoskeleton organization -0.544 0.391 -9999.0 0.0 -0.718 152.0 152.0 Nephrin/NEPH1 -0.386 0.281 -9999.0 0.0 -0.559 135.0 135.0 Nephrin/NEPH1/ZO-1 -0.419 0.303 -9999.0 0.0 -0.608 135.0 135.0