Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.039 0.199 -9999.0 0.0 -0.418 80.0 80.0 MAP3K8 0.016 0.04 -9999.0 0.0 -0.166 16.0 16.0 FOS -0.038 0.176 -9999.0 0.0 -0.438 62.0 62.0 PRKCA 0.02 0.025 -9999.0 0.0 -0.432 1.0 1.0 PTPN7 -0.052 0.15 -9999.0 0.0 -0.392 65.0 65.0 HRAS 0.024 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.012 0.101 -9999.0 0.0 -0.223 64.0 64.0 NRAS 0.021 0.01 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.034 0.025 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.029 0.156 -9999.0 0.0 -0.423 57.0 57.0 MAP2K1 0.002 0.113 -9999.0 0.0 -0.469 19.0 19.0 ELK1 0.021 0.017 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.007 0.092 -9999.0 0.0 -0.404 20.0 20.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.004 53.0 53.0 MAPK1 -0.033 0.164 -9999.0 0.0 -0.429 60.0 60.0 RAF1 -0.003 0.094 -9999.0 0.0 -0.443 18.0 18.0 KRAS 0.025 0.005 -9999.0 0.0 -9999.0 0.0 0.0