Clinical Features CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q amp_1p22.3 48 (24%) 151 0.0002063 0.0844 0.002807 1 0.00011841 0.0493 0.0043119 1 0.21691 1 0.91094 1 0.065478 1 1 1 amp_1q22 145 (73%) 54 1.823e-06 0.000797 6.7694e-08 2.98e-05 0.0041159 1 0.031879 1 0.060209 1 0.018681 1 0.2456 1 0.10968 1 amp_1q42.3 139 (70%) 60 0.00029586 0.12 0.00021618 0.0881 0.0043476 1 0.056038 1 0.30829 1 0.14033 1 0.41258 1 0.74554 1 amp_2p24.1 44 (22%) 155 0.0056751 1 0.61995 1 0.45627 1 0.53782 1 0.41612 1 0.75719 1 0.20468 1 0.91599 1 amp_2q31.2 39 (20%) 160 0.021758 1 0.95051 1 0.55899 1 0.82301 1 0.0198 1 0.11212 1 0.55122 1 0.61793 1 amp_3q26.31 42 (21%) 157 0.00021603 0.0881 0.074952 1 0.58777 1 0.17164 1 0.00051639 0.206 0.018065 1 0.036057 1 0.049957 1 amp_4q13.3 17 (9%) 182 0.22509 1 0.55552 1 0.35869 1 0.57274 1 1 1 0.65028 1 0.64807 1 0.78448 1 amp_5p15.33 92 (46%) 107 4.5018e-06 0.00196 0.059904 1 0.078998 1 0.23528 1 0.38875 1 0.32658 1 0.093384 1 0.51027 1 amp_5q35.3 65 (33%) 134 2.9105e-05 0.0125 0.029716 1 0.66414 1 0.71617 1 1 1 0.94817 1 0.25677 1 0.74406 1 amp_6p25.2 87 (44%) 112 6.8881e-09 3.06e-06 0.00017288 0.0711 8.649e-05 0.0364 0.012155 1 0.41968 1 0.82284 1 0.54739 1 1 1 amp_6p21.1 87 (44%) 112 6.8881e-09 3.06e-06 5.6176e-06 0.00244 0.00083656 0.329 0.0084999 1 0.32628 1 0.52786 1 0.35859 1 0.67359 1 amp_6q12 63 (32%) 136 1.6497e-07 7.24e-05 0.024269 1 0.0054219 1 0.063132 1 0.19198 1 0.8706 1 0.51399 1 0.90599 1 amp_6q12 46 (23%) 153 0.00013117 0.0544 0.0067877 1 0.0041278 1 0.057897 1 0.48266 1 0.96325 1 0.18053 1 0.54536 1 amp_7q21.2 70 (35%) 129 0.24064 1 0.20556 1 0.36788 1 0.28319 1 0.21388 1 0.55635 1 0.49392 1 0.35191 1 amp_7q31.2 68 (34%) 131 0.36451 1 0.21541 1 0.35084 1 0.56364 1 0.15421 1 0.40907 1 0.46929 1 0.40008 1 amp_8q11.1 79 (40%) 120 1.7523e-10 7.8e-08 0.73383 1 0.12568 1 0.0013605 0.529 0.66105 1 0.25691 1 0.37079 1 0.16466 1 amp_8q24.21 119 (60%) 80 3.424e-13 1.53e-10 0.060436 1 0.083366 1 6.1922e-05 0.0263 0.14485 1 0.51684 1 0.58205 1 0.70871 1 amp_9q34.2 29 (15%) 170 0.14429 1 0.59279 1 0.057602 1 0.12974 1 0.19199 1 0.61007 1 0.17393 1 0.70998 1 amp_10p15.1 41 (21%) 158 0.52287 1 0.042611 1 0.21274 1 0.053262 1 0.14451 1 0.79484 1 0.32305 1 0.38822 1 amp_11q13.3 38 (19%) 161 0.40013 1 0.71319 1 0.068802 1 0.4997 1 0.1015 1 0.30994 1 0.084007 1 0.74037 1 amp_13q32.3 37 (19%) 162 6.8994e-05 0.0292 0.014103 1 0.0012494 0.487 0.025968 1 0.38686 1 0.5863 1 0.015936 1 0.25666 1 amp_15q26.3 32 (16%) 167 0.0075513 1 0.21764 1 0.37437 1 0.14229 1 0.38981 1 0.31844 1 0.17556 1 0.085618 1 amp_16q12.1 20 (10%) 179 0.59661 1 0.91895 1 0.12793 1 0.59349 1 0.83463 1 0.447 1 0.30999 1 0.47719 1 amp_17p11.2 30 (15%) 169 0.031973 1 0.11043 1 0.64256 1 0.27542 1 0.78453 1 0.89685 1 0.40043 1 0.69694 1 amp_17q25.3 86 (43%) 113 0.00016641 0.0687 0.0026908 1 0.066606 1 0.092907 1 0.17615 1 0.18834 1 0.11583 1 0.24535 1 amp_19q13.11 54 (27%) 145 0.10975 1 0.00044027 0.176 0.00030955 0.124 0.00030062 0.121 0.25181 1 0.0041097 1 0.0015196 0.588 0.004049 1 amp_20q13.33 69 (35%) 130 0.00065055 0.256 0.021449 1 2.1039e-05 0.00905 0.0072443 1 0.21839 1 0.22263 1 0.0049237 1 0.083133 1 amp_xq28 48 (24%) 151 9.2052e-05 0.0387 0.026251 1 0.13628 1 0.31665 1 0.071696 1 0.00884 1 0.15679 1 0.089018 1 del_1p36.23 93 (47%) 106 0.00027225 0.11 1.4495e-05 0.00625 7.9994e-05 0.0338 0.015547 1 0.60233 1 0.090244 1 0.011178 1 0.10147 1 del_2q22.1 25 (13%) 174 0.019453 1 0.9671 1 0.49989 1 0.8824 1 0.0065304 1 0.37532 1 0.95333 1 0.38173 1 del_2q37.3 42 (21%) 157 0.0083358 1 0.86951 1 0.0057727 1 0.01794 1 0.00019476 0.0799 0.053311 1 0.25293 1 0.27919 1 del_3p13 42 (21%) 157 0.060063 1 0.095554 1 0.0053081 1 0.00011243 0.0469 0.1003 1 0.084659 1 4.0156e-05 0.0171 0.0027034 1 del_4p16.3 44 (22%) 155 0.0031489 1 0.0057218 1 0.064263 1 0.13642 1 0.74326 1 0.34397 1 0.83166 1 0.29624 1 del_4q24 93 (47%) 106 6.0116e-08 2.65e-05 0.0067303 1 0.0019758 0.759 0.02292 1 0.2622 1 0.66885 1 0.4128 1 0.61437 1 del_4q34.3 85 (43%) 114 3.1633e-07 0.000139 0.00016692 0.0688 0.0011091 0.435 0.045759 1 0.86598 1 0.26922 1 0.2688 1 0.26258 1 del_6q16.3 69 (35%) 130 0.086864 1 0.49143 1 0.18041 1 0.42075 1 0.52798 1 0.50152 1 0.79172 1 0.9424 1 del_6q27 72 (36%) 127 0.0069972 1 0.3966 1 0.40674 1 0.41012 1 0.86458 1 0.040385 1 0.50145 1 0.2314 1 del_8p23.2 128 (64%) 71 1.6109e-11 7.2e-09 0.0081841 1 0.020109 1 0.44118 1 0.85505 1 0.52932 1 0.77968 1 0.49499 1 del_9p21.3 80 (40%) 119 2.9273e-05 0.0125 0.20043 1 0.11743 1 0.3935 1 0.22501 1 0.15819 1 0.2072 1 0.088905 1 del_9q34.2 64 (32%) 135 0.0080888 1 0.10077 1 0.0098159 1 0.0088262 1 0.39246 1 0.37019 1 0.53056 1 0.28493 1 del_10q23.31 60 (30%) 139 0.011904 1 0.3017 1 3.2505e-06 0.00142 0.0040609 1 0.094717 1 0.021465 1 0.00042238 0.169 0.11981 1 del_10q24.33 61 (31%) 138 0.030436 1 0.80666 1 4.7008e-05 0.02 0.0037848 1 0.088938 1 0.030423 1 0.0020271 0.776 0.21227 1 del_11q14.1 44 (22%) 155 0.093954 1 0.19066 1 0.3537 1 0.33837 1 0.60904 1 0.92065 1 0.52174 1 0.68952 1 del_11q23.3 51 (26%) 148 0.037888 1 0.0098662 1 0.37546 1 0.47887 1 0.56105 1 0.88314 1 0.14446 1 0.77456 1 del_12p12.1 46 (23%) 153 0.3688 1 0.11139 1 0.0014378 0.558 0.3707 1 0.025185 1 0.046723 1 0.034504 1 0.0025734 0.983 del_12q24.33 36 (18%) 163 0.012863 1 0.18853 1 0.60668 1 0.64227 1 0.88825 1 0.8431 1 0.51313 1 0.59657 1 del_13q12.11 67 (34%) 132 9.6681e-05 0.0404 0.069008 1 0.030727 1 0.0064799 1 0.93965 1 0.18056 1 0.044406 1 0.07703 1 del_13q14.2 94 (47%) 105 5.307e-11 2.37e-08 0.084636 1 0.0017376 0.671 9.2258e-05 0.0387 0.2622 1 0.13296 1 0.00021894 0.0889 0.046623 1 del_13q22.2 74 (37%) 125 1.3061e-08 5.77e-06 0.099397 1 0.050633 1 0.00059041 0.234 0.44484 1 0.43388 1 0.00061465 0.243 0.23276 1 del_14q23.3 69 (35%) 130 0.0056781 1 0.5502 1 0.0080047 1 0.28599 1 0.35262 1 0.015128 1 0.0097394 1 0.027441 1 del_14q32.33 70 (35%) 129 5.4563e-05 0.0232 0.29023 1 0.064153 1 0.18052 1 0.11766 1 0.063603 1 0.041125 1 0.13006 1 del_16q23.1 83 (42%) 116 6.5782e-06 0.00285 0.0005224 0.207 8.8432e-06 0.00382 0.0011258 0.44 0.62794 1 0.041276 1 0.037119 1 0.093084 1 del_17p11.2 111 (56%) 88 0.0054308 1 0.11496 1 0.0056039 1 0.066649 1 0.00015127 0.0626 0.0025913 0.987 0.0044344 1 0.001832 0.705 del_19p13.3 46 (23%) 153 0.00037552 0.151 0.06453 1 0.01666 1 0.036888 1 0.3314 1 0.11567 1 0.33434 1 0.21401 1 del_20p12.1 14 (7%) 185 0.32853 1 0.49147 1 0.41838 1 0.81213 1 0.59294 1 0.63908 1 0.66196 1 0.38651 1 del_22q13.32 59 (30%) 140 0.60604 1 0.89024 1 0.0244 1 0.063597 1 0.63976 1 0.74543 1 0.50705 1 0.59884 1