Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.026 0.177 0.673 12.0 -9999.0 0.0 12.0 KIRREL -0.051 0.212 0.349 1.0 -0.865 12.0 13.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.026 0.178 -9999.0 0.0 -0.675 12.0 12.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.017 0.14 -9999.0 0.0 -0.519 12.0 12.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.013 0.099 -9999.0 0.0 -0.381 11.0 11.0 FYN -0.025 0.122 -9999.0 0.0 -0.489 12.0 12.0 mol:Ca2+ -0.017 0.138 -9999.0 0.0 -0.513 12.0 12.0 mol:DAG -0.017 0.139 -9999.0 0.0 -0.516 12.0 12.0 NPHS2 0.003 0.045 0.332 3.0 -9999.0 0.0 3.0 mol:IP3 -0.017 0.139 -9999.0 0.0 -0.516 12.0 12.0 regulation of endocytosis -0.015 0.124 -9999.0 0.0 -0.458 12.0 12.0 Nephrin/NEPH1/podocin/Cholesterol -0.018 0.141 -9999.0 0.0 -0.525 12.0 12.0 establishment of cell polarity -0.026 0.177 -9999.0 0.0 -0.673 12.0 12.0 Nephrin/NEPH1/podocin/NCK1-2 -0.014 0.131 -9999.0 0.0 -0.475 12.0 12.0 Nephrin/NEPH1/beta Arrestin2 -0.015 0.126 -9999.0 0.0 -0.464 12.0 12.0 NPHS1 0.02 0.089 0.345 13.0 -9999.0 0.0 13.0 Nephrin/NEPH1/podocin -0.015 0.134 -9999.0 0.0 -0.492 12.0 12.0 TJP1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.002 0.025 0.341 1.0 -9999.0 0.0 1.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.017 0.14 -9999.0 0.0 -0.519 12.0 12.0 CD2AP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.017 0.14 -9999.0 0.0 -0.519 12.0 12.0 GRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.007 0.136 -9999.0 0.0 -0.479 12.0 12.0 cytoskeleton organization -0.02 0.126 -9999.0 0.0 -0.485 12.0 12.0 Nephrin/NEPH1 -0.019 0.136 -9999.0 0.0 -0.511 12.0 12.0 Nephrin/NEPH1/ZO-1 -0.021 0.148 -9999.0 0.0 -0.558 12.0 12.0