Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.072	0.247	0.578	9.0	-0.647	13.0	22.0
IHH	0.014	0.208	0.404	9.0	-0.858	8.0	17.0
SHH Np/Cholesterol/GAS1	-0.115	0.24	-9999.0	0.0	-0.58	38.0	38.0
LRPAP1	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.114	0.237	0.574	38.0	-9999.0	0.0	38.0
SMO/beta Arrestin2	-0.005	0.228	0.363	1.0	-0.723	14.0	15.0
SMO	-0.005	0.245	0.409	1.0	-0.772	14.0	15.0
AKT1	0.008	0.153	0.268	1.0	-0.468	8.0	9.0
ARRB2	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.011	0.059	0.341	6.0	-9999.0	0.0	6.0
ADRBK1	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.003	0.24	0.408	1.0	-0.752	14.0	15.0
STIL	0.009	0.222	0.377	4.0	-0.618	14.0	18.0
DHH N/PTCH2	-0.001	0.054	-9999.0	0.0	-0.671	1.0	1.0
DHH N/PTCH1	0.006	0.211	0.382	2.0	-0.66	13.0	15.0
PIK3CA	-0.005	0.062	-9999.0	0.0	-0.864	1.0	1.0
DHH	0.002	0.025	0.341	1.0	-9999.0	0.0	1.0
PTHLH	0.078	0.263	0.558	9.0	-0.706	13.0	22.0
determination of left/right symmetry	-0.003	0.24	0.408	1.0	-0.752	14.0	15.0
PIK3R1	-0.005	0.062	-9999.0	0.0	-0.864	1.0	1.0
skeletal system development	0.078	0.262	0.557	9.0	-0.699	13.0	22.0
IHH N/Hhip	-0.343	0.389	0.287	1.0	-0.729	94.0	95.0
DHH N/Hhip	-0.314	0.339	-9999.0	0.0	-0.672	90.0	90.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.003	0.24	0.408	1.0	-0.752	14.0	15.0
pancreas development	-0.404	0.433	0.34	1.0	-0.862	90.0	91.0
HHAT	-0.001	0.072	0.341	2.0	-0.864	1.0	3.0
PI3K	-0.006	0.087	-9999.0	0.0	-1.21	1.0	1.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.14	0.319	-9999.0	0.0	-0.864	31.0	31.0
somite specification	-0.003	0.24	0.408	1.0	-0.752	14.0	15.0
SHH Np/Cholesterol/PTCH1	-0.017	0.222	0.349	1.0	-0.601	19.0	20.0
SHH Np/Cholesterol/PTCH2	-0.029	0.138	-9999.0	0.0	-0.591	10.0	10.0
SHH Np/Cholesterol/Megalin	-0.087	0.231	-9999.0	0.0	-0.556	35.0	35.0
SHH	-0.033	0.161	-9999.0	0.0	-0.732	9.0	9.0
catabolic process	0.035	0.236	0.387	9.0	-0.702	14.0	23.0
SMO/Vitamin D3	-0.012	0.249	0.353	6.0	-0.641	20.0	26.0
SHH Np/Cholesterol/Hhip	-0.281	0.292	-9999.0	0.0	-0.562	96.0	96.0
LRP2	-0.096	0.316	0.341	12.0	-0.864	26.0	38.0
receptor-mediated endocytosis	-0.059	0.259	0.34	1.0	-0.711	17.0	18.0
SHH Np/Cholesterol/BOC	-0.021	0.136	-9999.0	0.0	-0.592	9.0	9.0
SHH Np/Cholesterol/CDO	-0.027	0.132	-9999.0	0.0	-0.596	9.0	9.0
mesenchymal cell differentiation	0.278	0.289	0.557	96.0	-9999.0	0.0	96.0
mol:Vitamin D3	-0.007	0.232	0.353	6.0	-0.602	19.0	25.0
IHH N/PTCH2	0.0	0.145	0.287	1.0	-0.587	9.0	10.0
CDON	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
IHH N/PTCH1	0.024	0.251	0.44	11.0	-0.709	14.0	25.0
Megalin/LRPAP1	-0.077	0.242	-9999.0	0.0	-0.671	26.0	26.0
PTCH2	-0.003	0.067	0.341	1.0	-0.864	1.0	2.0
SHH Np/Cholesterol	-0.026	0.135	-9999.0	0.0	-0.604	9.0	9.0
PTCH1	0.035	0.237	0.388	9.0	-0.705	14.0	23.0
HHIP	-0.405	0.434	0.341	1.0	-0.864	90.0	91.0