Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.119	0.28	0.533	46.0	-0.583	6.0	52.0
IHH	0.063	0.172	0.347	19.0	-0.413	12.0	31.0
SHH Np/Cholesterol/GAS1	-0.054	0.156	-9999.0	0.0	-0.403	27.0	27.0
LRPAP1	0.025	0.005	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.054	0.155	0.4	27.0	-9999.0	0.0	27.0
SMO/beta Arrestin2	0.061	0.219	0.382	17.0	-0.543	14.0	31.0
SMO	0.049	0.228	0.408	16.0	-0.589	13.0	29.0
AKT1	0.048	0.165	0.314	4.0	-0.551	5.0	9.0
ARRB2	0.022	0.009	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.036	0.058	0.356	6.0	-9999.0	0.0	6.0
ADRBK1	0.025	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	0.049	0.225	0.407	16.0	-0.578	13.0	29.0
STIL	0.088	0.202	0.425	22.0	-0.422	12.0	34.0
DHH N/PTCH2	0.035	0.044	0.256	2.0	-0.464	1.0	3.0
DHH N/PTCH1	0.077	0.2	0.417	17.0	-0.474	12.0	29.0
PIK3CA	0.022	0.047	-9999.0	0.0	-0.62	1.0	1.0
DHH	0.026	0.024	0.356	1.0	-9999.0	0.0	1.0
PTHLH	0.135	0.317	0.612	44.0	-0.66	6.0	50.0
determination of left/right symmetry	0.049	0.225	0.407	16.0	-0.578	13.0	29.0
PIK3R1	0.022	0.047	-9999.0	0.0	-0.62	1.0	1.0
skeletal system development	0.135	0.316	0.611	44.0	-0.654	6.0	50.0
IHH N/Hhip	-0.195	0.288	0.294	2.0	-0.49	87.0	89.0
DHH N/Hhip	-0.187	0.247	0.256	2.0	-0.45	86.0	88.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	0.049	0.225	0.407	16.0	-0.578	13.0	29.0
pancreas development	-0.263	0.316	0.356	1.0	-0.601	86.0	87.0
HHAT	0.017	0.048	-9999.0	0.0	-0.62	1.0	1.0
PI3K	0.032	0.063	-9999.0	0.0	-0.829	1.0	1.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.08	0.237	-9999.0	0.0	-0.61	31.0	31.0
somite specification	0.049	0.225	0.407	16.0	-0.578	13.0	29.0
SHH Np/Cholesterol/PTCH1	0.026	0.176	0.398	6.0	-0.417	16.0	22.0
SHH Np/Cholesterol/PTCH2	-0.001	0.093	0.215	1.0	-0.406	8.0	9.0
SHH Np/Cholesterol/Megalin	-0.034	0.16	0.238	12.0	-0.377	27.0	39.0
SHH	-0.011	0.111	0.257	2.0	-0.508	8.0	10.0
catabolic process	0.084	0.237	0.412	44.0	-0.521	12.0	56.0
SMO/Vitamin D3	0.071	0.231	0.462	16.0	-0.462	18.0	34.0
SHH Np/Cholesterol/Hhip	-0.148	0.192	0.219	1.0	-0.337	86.0	87.0
LRP2	-0.045	0.245	0.356	12.0	-0.62	26.0	38.0
receptor-mediated endocytosis	0.008	0.227	0.384	13.0	-0.485	20.0	33.0
SHH Np/Cholesterol/BOC	0.005	0.095	0.218	5.0	-0.392	8.0	13.0
SHH Np/Cholesterol/CDO	-0.001	0.09	-9999.0	0.0	-0.404	8.0	8.0
mesenchymal cell differentiation	0.147	0.19	0.335	86.0	-0.217	1.0	87.0
mol:Vitamin D3	0.085	0.215	0.476	15.0	-0.418	16.0	31.0
IHH N/PTCH2	0.05	0.118	0.282	4.0	-0.41	7.0	11.0
CDON	0.025	0.005	-9999.0	0.0	-9999.0	0.0	0.0
IHH N/PTCH1	0.103	0.248	0.439	46.0	-0.524	12.0	58.0
Megalin/LRPAP1	-0.02	0.186	0.256	12.0	-0.464	26.0	38.0
PTCH2	0.023	0.053	0.356	1.0	-0.62	1.0	2.0
SHH Np/Cholesterol	-0.007	0.088	-9999.0	0.0	-0.404	8.0	8.0
PTCH1	0.084	0.238	0.412	44.0	-0.523	12.0	56.0
HHIP	-0.264	0.317	0.356	1.0	-0.601	86.0	87.0