Clinical Features MRNA_CNMF MRNA_CHIERARCHICAL MIR_CNMF MIR_CHIERARCHICAL CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q amp_1p34.3 287 (50%) 282 0.42741 1 0.48502 1 0.12293 1 0.07902 1 9.7188e-07 0.000892 0.1942 1 0.11213 1 0.80806 1 0.5487 1 0.054708 1 0.08385 1 0.1016 1 0.065208 1 0.59989 1 amp_1q21.3 361 (63%) 208 0.26626 1 0.34166 1 0.63325 1 0.15363 1 3.6969e-11 3.47e-08 0.0001231 0.11 0.074999 1 0.020764 1 0.65819 1 0.3495 1 0.83952 1 0.8884 1 0.73708 1 0.82716 1 amp_1q42.2 314 (55%) 255 0.023225 1 0.028808 1 0.87286 1 0.0071757 1 1.173e-09 1.09e-06 5.4163e-05 0.0485 0.25234 1 0.21608 1 0.50065 1 0.37446 1 0.26698 1 0.35132 1 0.35742 1 0.26424 1 amp_2p23.2 245 (43%) 324 0.32705 1 0.44066 1 0.75018 1 0.010572 1 1.1934e-08 1.11e-05 0.0043789 1 0.1436 1 0.44438 1 0.031771 1 0.81369 1 0.91857 1 0.12692 1 0.9302 1 0.71001 1 amp_2q31.2 259 (46%) 310 0.11314 1 0.094175 1 0.03297 1 0.060366 1 4.1836e-09 3.89e-06 0.007844 1 0.048608 1 0.31665 1 0.1522 1 0.42492 1 0.2868 1 0.39694 1 0.08213 1 0.074353 1 amp_3q26.2 476 (84%) 93 0.0090939 1 0.004886 1 0.80893 1 0.3479 1 1.8487e-10 1.73e-07 0.034723 1 0.40792 1 0.44484 1 0.0075878 1 0.014744 1 0.12526 1 0.39324 1 0.47604 1 0.64314 1 amp_4p16.3 157 (28%) 412 1 1 0.27906 1 0.029283 1 0.60698 1 0.00029229 0.257 0.027426 1 0.27552 1 0.7467 1 0.68955 1 0.40208 1 0.62419 1 0.62056 1 0.74343 1 0.45595 1 amp_4q13.3 110 (19%) 459 0.94456 1 0.90469 1 0.34375 1 0.10604 1 0.00032229 0.282 0.52762 1 0.52517 1 0.2254 1 0.13011 1 0.89526 1 1 1 0.10385 1 0.86558 1 0.52368 1 amp_5p15.33 304 (53%) 265 1 1 0.9649 1 0.62519 1 0.60579 1 8.6691e-07 0.000797 0.099018 1 0.97594 1 0.28685 1 0.24906 1 0.96293 1 0.0246 1 0.54424 1 0.10546 1 0.50039 1 amp_6p22.3 300 (53%) 269 0.17261 1 0.046234 1 0.27542 1 0.10918 1 1.0672e-06 0.000979 0.01231 1 0.072297 1 0.049911 1 0.85166 1 0.093415 1 0.37279 1 0.4444 1 0.16963 1 0.27697 1 amp_7q36.3 311 (55%) 258 0.10536 1 0.091021 1 0.35161 1 0.73125 1 2.8193e-05 0.0253 0.45664 1 0.031387 1 0.1551 1 0.83678 1 0.55614 1 0.21284 1 0.17407 1 0.022716 1 0.26424 1 amp_8p11.21 207 (36%) 362 0.10754 1 0.023535 1 0.10015 1 0.13302 1 1.9087e-05 0.0173 0.015866 1 0.010835 1 0.28222 1 0.28111 1 0.16706 1 0.76317 1 0.75774 1 0.6739 1 0.86897 1 amp_8q24.21 451 (79%) 118 1.3184e-07 0.000122 2.3033e-05 0.0208 0.25056 1 0.0024369 1 1.9649e-16 1.87e-13 0.0044509 1 0.98209 1 0.65809 1 4.1772e-07 0.000385 2.6338e-05 0.0237 0.16089 1 0.037731 1 0.061281 1 0.071051 1 amp_10p15.3 246 (43%) 323 0.82149 1 0.70988 1 0.055072 1 0.24098 1 2.0596e-12 1.95e-09 0.0005335 0.466 0.49093 1 0.3366 1 0.23327 1 0.42105 1 0.37272 1 0.88275 1 0.59964 1 0.63309 1 amp_10q22.3 181 (32%) 388 0.4721 1 0.64531 1 0.54132 1 0.15985 1 0.21481 1 0.75108 1 0.63553 1 0.96201 1 0.20144 1 0.57043 1 0.26617 1 0.23594 1 0.90464 1 0.40648 1 amp_11q14.1 253 (44%) 316 0.0052299 1 0.045435 1 0.76692 1 0.46668 1 6.611e-07 0.000608 0.0024507 1 0.38199 1 0.24972 1 0.0042186 1 0.0076436 1 0.13285 1 0.72233 1 0.21519 1 1 1 amp_12p13.33 323 (57%) 246 0.023451 1 0.1224 1 0.26294 1 0.0080109 1 1.1348e-08 1.05e-05 0.00021342 0.189 0.1904 1 0.47224 1 0.014798 1 0.16359 1 0.53129 1 1 1 0.82841 1 0.48191 1 amp_12p12.1 306 (54%) 263 0.12949 1 0.10984 1 0.89905 1 0.063609 1 5.628e-12 5.32e-09 3.2202e-05 0.0289 0.62369 1 0.21577 1 0.012326 1 0.10764 1 0.44699 1 0.94413 1 0.71972 1 0.89705 1 amp_14q11.2 146 (26%) 423 0.017105 1 0.036774 1 0.28682 1 0.0010186 0.885 0.038822 1 0.19358 1 0.52867 1 0.39835 1 0.34017 1 0.27022 1 0.29515 1 0.43753 1 0.22051 1 0.26239 1 amp_14q32.33 153 (27%) 416 0.44281 1 0.49697 1 0.19723 1 0.76377 1 0.00026292 0.231 0.28117 1 1 1 0.53663 1 0.16328 1 0.65815 1 0.37172 1 0.62542 1 0.48384 1 0.58882 1 amp_15q26.3 161 (28%) 408 0.085685 1 0.30067 1 0.50358 1 0.8259 1 3.2772e-09 3.05e-06 0.78821 1 0.97938 1 0.30783 1 0.20923 1 0.97687 1 0.15448 1 0.4633 1 0.1619 1 0.49002 1 amp_17q25.3 212 (37%) 357 0.46806 1 0.72597 1 0.9797 1 0.17358 1 0.0022463 1 0.77998 1 0.073369 1 0.065226 1 0.012307 1 0.018682 1 0.32549 1 0.12492 1 0.29546 1 0.1103 1 amp_18q11.2 142 (25%) 427 0.81885 1 0.98508 1 0.95348 1 0.49308 1 1.8251e-05 0.0166 0.0037882 1 0.15009 1 0.25815 1 0.041861 1 0.09141 1 0.14573 1 0.53964 1 0.16949 1 0.2765 1 amp_19p13.12 308 (54%) 261 0.00022899 0.202 2.0051e-07 0.000185 0.037705 1 0.02498 1 1.2739e-11 1.2e-08 2.356e-06 0.00215 0.00031248 0.274 0.0016392 1 0.24142 1 0.31415 1 0.57613 1 0.59783 1 0.98103 1 0.7633 1 amp_19q12 319 (56%) 250 0.12369 1 0.0051381 1 0.029229 1 0.062371 1 1.3826e-27 1.32e-24 4.5555e-10 4.26e-07 0.046767 1 0.6915 1 0.53024 1 0.84301 1 0.34553 1 0.6757 1 0.82715 1 0.49443 1 amp_19q13.2 241 (42%) 328 0.93768 1 0.84363 1 0.65757 1 0.19312 1 1.2564e-11 1.18e-08 9.8378e-05 0.0878 0.44408 1 0.46817 1 0.37065 1 1 1 0.96956 1 0.4328 1 0.70736 1 0.43271 1 amp_20p13 313 (55%) 256 0.46779 1 0.060789 1 0.13999 1 0.035661 1 5.493e-11 5.15e-08 2.2937e-05 0.0207 0.19493 1 0.9831 1 0.081551 1 0.71837 1 0.19024 1 0.84091 1 0.65814 1 0.27935 1 amp_20q11.21 340 (60%) 229 0.0026729 1 0.0024645 1 0.11101 1 0.00025809 0.227 4.3418e-22 4.13e-19 8.5827e-12 8.1e-09 0.13079 1 0.02209 1 0.00025599 0.226 0.50617 1 0.28881 1 0.17344 1 0.73351 1 0.48535 1 amp_20q13.33 393 (69%) 176 0.010407 1 0.020113 1 0.68381 1 0.0037458 1 4.8089e-16 4.56e-13 2.0833e-06 0.00191 0.84293 1 0.49425 1 0.0080437 1 0.8089 1 0.46977 1 0.59505 1 0.69386 1 0.30758 1 amp_22q12.2 89 (16%) 480 0.61512 1 0.57693 1 0.069688 1 0.25903 1 0.0015508 1 0.00069033 0.601 0.97365 1 0.035972 1 0.06298 1 0.1233 1 0.10548 1 0.0095847 1 0.037407 1 0.029915 1 amp_xp11.23 154 (27%) 415 0.66238 1 0.32173 1 0.42509 1 0.34934 1 2.1139e-05 0.0191 0.0017138 1 0.71586 1 0.25178 1 0.44166 1 0.34146 1 0.27271 1 1 1 0.44836 1 0.91713 1 amp_xq28 217 (38%) 352 0.24411 1 0.31042 1 0.56109 1 0.05106 1 0.0011689 1 0.17502 1 0.44971 1 0.72714 1 0.62025 1 0.75846 1 0.87139 1 0.015152 1 0.86799 1 1 1 del_1p36.11 267 (47%) 302 0.73933 1 0.51743 1 0.029195 1 0.39334 1 9.812e-06 0.00895 0.088976 1 0.12426 1 0.21401 1 0.83602 1 0.87105 1 0.22225 1 0.14759 1 0.33798 1 0.15424 1 del_1q41 95 (17%) 474 0.086608 1 0.58904 1 0.30261 1 0.41881 1 3.2299e-07 0.000298 0.1323 1 0.47473 1 0.097035 1 0.26804 1 0.53781 1 0.91312 1 0.65666 1 0.7634 1 0.88418 1 del_2p25.3 120 (21%) 449 0.88263 1 1 1 0.40872 1 0.27864 1 0.2451 1 0.64004 1 0.26408 1 0.13708 1 0.062531 1 0.51808 1 0.8775 1 0.5123 1 0.89293 1 0.6085 1 del_2q22.1 136 (24%) 433 0.10469 1 0.14251 1 0.56811 1 0.15082 1 0.086744 1 0.67205 1 0.60311 1 0.84437 1 0.8944 1 0.31363 1 0.47906 1 0.36913 1 0.41799 1 0.10764 1 del_2q37.3 173 (30%) 396 0.016265 1 0.039294 1 0.75839 1 0.0014925 1 1.1381e-05 0.0104 0.065268 1 0.79836 1 0.99383 1 0.015753 1 0.020931 1 0.01326 1 0.010925 1 0.051973 1 0.021767 1 del_3p26.2 209 (37%) 360 0.14968 1 0.12981 1 0.0057489 1 0.034069 1 1.7773e-05 0.0161 0.00056478 0.493 0.95455 1 0.094867 1 0.0031791 1 0.66503 1 0.62212 1 0.62816 1 0.97089 1 0.026535 1 del_4q22.1 388 (68%) 181 0.052697 1 0.12344 1 1 1 0.0077117 1 0.020387 1 0.22088 1 0.1914 1 0.026384 1 0.072244 1 0.50849 1 0.29927 1 0.0097739 1 0.029197 1 0.15429 1 del_4q34.3 415 (73%) 154 0.05409 1 0.039684 1 0.062901 1 0.024206 1 0.14975 1 0.59552 1 0.66716 1 0.31371 1 0.088586 1 0.02911 1 0.41844 1 0.19934 1 0.16081 1 0.26869 1 del_5q11.2 347 (61%) 222 0.92924 1 0.63541 1 0.64385 1 0.2061 1 1.5627e-08 1.45e-05 0.00032861 0.288 0.73061 1 0.79974 1 0.20714 1 0.17086 1 0.090549 1 0.0019101 1 0.065188 1 0.063275 1 del_5q13.2 412 (72%) 157 0.74464 1 0.63285 1 0.89629 1 0.75987 1 3.5656e-11 3.35e-08 0.1025 1 0.77277 1 0.81648 1 0.51946 1 0.0056285 1 0.15387 1 0.011862 1 0.20991 1 0.16991 1 del_6q27 381 (67%) 188 0.16838 1 0.040689 1 0.25718 1 0.017427 1 4.0901e-10 3.83e-07 2.5821e-05 0.0232 0.45882 1 0.86844 1 1.7468e-05 0.0159 0.34197 1 0.36646 1 0.9062 1 0.33564 1 0.085071 1 del_7p22.1 248 (44%) 321 0.39068 1 0.61069 1 0.76609 1 0.67663 1 1.6871e-13 1.6e-10 0.63129 1 0.80271 1 0.71665 1 0.35034 1 0.13054 1 0.35423 1 0.64333 1 0.70203 1 0.59299 1 del_8p23.3 382 (67%) 187 0.044596 1 0.24242 1 0.57242 1 0.01366 1 6.5581e-12 6.2e-09 0.050602 1 0.888 1 0.52019 1 0.88333 1 0.59724 1 0.2394 1 0.14546 1 0.16665 1 0.36567 1 del_8p21.2 400 (70%) 169 0.043047 1 0.43965 1 0.17829 1 0.0088678 1 3.9482e-09 3.68e-06 0.14533 1 0.87054 1 0.89895 1 0.45824 1 0.20665 1 0.57492 1 0.49662 1 0.90789 1 1 1 del_9p24.3 257 (45%) 312 0.00023684 0.209 0.011869 1 0.61189 1 0.0091127 1 0.038572 1 7.4998e-05 0.067 0.31827 1 0.4479 1 0.071174 1 0.07229 1 0.086378 1 0.16768 1 0.063054 1 0.15666 1 del_9q34.13 337 (59%) 232 0.02828 1 0.036905 1 0.96822 1 0.016465 1 6.0351e-07 0.000556 0.057586 1 0.42123 1 0.37933 1 0.2077 1 1 1 0.034492 1 0.12787 1 0.13108 1 0.07979 1 del_10p15.3 120 (21%) 449 0.17973 1 0.046738 1 0.087446 1 0.092048 1 0.14863 1 0.34731 1 0.28435 1 0.045356 1 0.015383 1 0.057165 1 0.24593 1 0.32736 1 0.1137 1 0.26925 1 del_10q24.2 246 (43%) 323 0.0019688 1 0.00012383 0.11 0.0062218 1 0.068116 1 2.3668e-05 0.0213 0.0015559 1 0.011462 1 9.2118e-05 0.0823 0.4373 1 0.43904 1 0.0018677 1 0.35132 1 0.010636 1 0.0089752 1 del_11p15.5 338 (59%) 231 0.10832 1 0.44184 1 0.60211 1 0.031395 1 5.2217e-10 4.88e-07 0.0074102 1 0.93689 1 0.61563 1 0.70425 1 0.2497 1 0.10678 1 0.029904 1 0.15488 1 0.33028 1 del_11q25 195 (34%) 374 0.70855 1 0.64682 1 0.17326 1 0.3562 1 0.14759 1 0.44446 1 0.31984 1 0.1763 1 0.92824 1 0.8659 1 0.63509 1 0.18769 1 0.67597 1 0.2975 1 del_12q24.33 217 (38%) 352 0.0010389 0.902 0.00020177 0.179 0.16325 1 0.089147 1 3.9495e-09 3.68e-06 0.01951 1 0.29884 1 0.33534 1 0.051415 1 0.0019829 1 0.015193 1 0.0069466 1 0.018451 1 0.011616 1 del_13q14.2 358 (63%) 211 0.010235 1 0.020398 1 0.62079 1 0.61617 1 1.4448e-06 0.00132 2.3367e-05 0.0211 0.0019178 1 0.0012467 1 0.099367 1 0.23554 1 0.36554 1 0.86781 1 0.44635 1 0.63368 1 del_14q23.3 299 (53%) 270 0.064323 1 0.52647 1 0.65068 1 0.76753 1 0.00012257 0.109 0.73202 1 0.22238 1 0.28486 1 0.855 1 0.19643 1 0.89129 1 0.65449 1 0.70845 1 0.48195 1 del_15q15.1 360 (63%) 209 0.026514 1 0.0097023 1 0.02129 1 0.0060425 1 1.103e-11 1.04e-08 7.0557e-06 0.00644 0.1598 1 0.071387 1 0.010694 1 0.84378 1 0.39745 1 0.63617 1 0.19984 1 0.19085 1 del_16p13.3 307 (54%) 262 0.60155 1 0.11994 1 0.27581 1 0.61537 1 0.053532 1 0.41812 1 0.82516 1 0.25066 1 0.35728 1 0.55582 1 0.22105 1 0.86307 1 0.11019 1 0.8285 1 del_16q22.1 453 (80%) 116 0.49637 1 0.73 1 0.031617 1 0.89195 1 0.00019338 0.172 0.63747 1 0.68953 1 0.33071 1 0.21849 1 0.18609 1 0.31239 1 0.097633 1 0.060337 1 0.12023 1 del_16q23.1 444 (78%) 125 0.11018 1 0.22949 1 0.10055 1 0.39426 1 1.0699e-05 0.00975 0.53578 1 0.80497 1 0.85978 1 0.27845 1 0.29801 1 0.057675 1 0.024932 1 0.040535 1 0.030094 1 del_17p12 483 (85%) 86 0.14364 1 0.24421 1 0.58727 1 0.60715 1 0.73734 1 0.31882 1 0.90203 1 0.26905 1 0.15035 1 0.40269 1 0.51019 1 0.51057 1 0.47107 1 0.77516 1 del_17q11.2 466 (82%) 103 0.92268 1 0.21631 1 0.7217 1 0.47063 1 0.00058111 0.507 0.0028613 1 0.76339 1 0.066981 1 0.36819 1 0.44384 1 0.14619 1 0.495 1 0.02644 1 0.37675 1 del_18q23 377 (66%) 192 0.97993 1 0.9919 1 0.14822 1 0.4062 1 0.015535 1 0.39567 1 0.32968 1 0.17048 1 0.12821 1 0.43536 1 0.47439 1 0.5438 1 0.075404 1 0.53782 1 del_19p13.3 502 (88%) 67 0.1559 1 0.0091677 1 0.82341 1 0.46179 1 0.00063353 0.552 0.017352 1 0.61616 1 0.27833 1 0.3214 1 0.016283 1 0.47848 1 0.80458 1 0.43549 1 0.90868 1 del_19q13.33 295 (52%) 274 0.00021672 0.192 0.0001497 0.133 0.04453 1 0.18822 1 0.097818 1 0.0026921 1 0.02891 1 0.18115 1 0.0068731 1 0.058394 1 0.32244 1 0.15914 1 0.29749 1 0.46905 1 del_19q13.43 279 (49%) 290 0.011411 1 0.0014636 1 0.096567 1 0.16297 1 0.0027893 1 2.7554e-05 0.0247 0.17417 1 0.35557 1 0.47848 1 0.12986 1 0.51962 1 0.50533 1 0.36539 1 0.68167 1 del_21q22.3 224 (39%) 345 0.36544 1 0.47168 1 0.69732 1 0.24641 1 0.80826 1 0.26299 1 0.65141 1 0.64223 1 0.24915 1 0.37317 1 0.81885 1 0.71159 1 0.19746 1 0.50242 1 del_22q13.32 495 (87%) 74 0.15937 1 0.07637 1 0.022628 1 0.069972 1 0.0053264 1 0.10118 1 0.10219 1 0.41075 1 0.10308 1 0.26997 1 0.030962 1 0.35073 1 0.027439 1 0.63547 1 del_xp21.1 350 (62%) 219 0.3977 1 0.65994 1 0.097141 1 0.80191 1 0.12427 1 0.02048 1 0.45386 1 0.060525 1 0.87333 1 0.37697 1 0.97395 1 0.68471 1 0.85442 1 0.7256 1