Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.278 0.304 0.577 41.0 -9999.0 0.0 41.0 KIRREL -0.101 0.255 -9999.0 0.0 -0.794 10.0 10.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.279 0.305 -9999.0 0.0 -0.578 41.0 41.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.219 0.25 -9999.0 0.0 -0.528 25.0 25.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.135 0.201 -9999.0 0.0 -0.409 22.0 22.0 FYN -0.194 0.254 -9999.0 0.0 -0.511 25.0 25.0 mol:Ca2+ -0.217 0.247 -9999.0 0.0 -0.522 25.0 25.0 mol:DAG -0.218 0.249 -9999.0 0.0 -0.525 25.0 25.0 NPHS2 -0.047 0.132 -9999.0 0.0 -0.713 3.0 3.0 mol:IP3 -0.218 0.249 -9999.0 0.0 -0.525 25.0 25.0 regulation of endocytosis -0.193 0.226 -9999.0 0.0 -0.477 25.0 25.0 Nephrin/NEPH1/podocin/Cholesterol -0.223 0.254 -9999.0 0.0 -0.463 41.0 41.0 establishment of cell polarity -0.278 0.304 -9999.0 0.0 -0.577 41.0 41.0 Nephrin/NEPH1/podocin/NCK1-2 -0.199 0.23 -9999.0 0.0 -0.519 18.0 18.0 Nephrin/NEPH1/beta Arrestin2 -0.178 0.245 -9999.0 0.0 -0.484 25.0 25.0 NPHS1 -0.283 0.354 -9999.0 0.0 -0.712 34.0 34.0 Nephrin/NEPH1/podocin -0.202 0.25 -9999.0 0.0 -0.514 25.0 25.0 TJP1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.219 0.25 -9999.0 0.0 -0.528 25.0 25.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.219 0.25 -9999.0 0.0 -0.528 25.0 25.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.197 0.265 -9999.0 0.0 -0.523 25.0 25.0 cytoskeleton organization -0.174 0.258 -9999.0 0.0 -0.515 25.0 25.0 Nephrin/NEPH1 -0.207 0.232 -9999.0 0.0 -0.43 41.0 41.0 Nephrin/NEPH1/ZO-1 -0.226 0.251 -9999.0 0.0 -0.531 25.0 25.0