Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.015 0.2 -9999.0 0.0 -0.67 5.0 5.0 MAP3K8 0.005 0.084 -9999.0 0.0 -0.766 1.0 1.0 FOS -0.023 0.195 -9999.0 0.0 -0.649 5.0 5.0 PRKCA 0.015 0.003 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 -0.035 0.186 -9999.0 0.0 -0.706 6.0 6.0 HRAS 0.007 0.071 -9999.0 0.0 -0.648 1.0 1.0 PRKCB -0.114 0.281 -9999.0 0.0 -0.72 15.0 15.0 NRAS 0.014 0.001 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP -0.004 0.039 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.02 0.171 -9999.0 0.0 -0.781 3.0 3.0 MAP2K1 -0.032 0.187 -9999.0 0.0 -0.524 9.0 9.0 ELK1 0.015 0.003 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.072 0.162 -9999.0 0.0 -0.501 9.0 9.0 mol:GTP 0.0 0.001 -9999.0 0.0 -0.005 3.0 3.0 MAPK1 -0.02 0.171 -9999.0 0.0 -0.657 4.0 4.0 RAF1 -0.072 0.162 -9999.0 0.0 -0.501 9.0 9.0 KRAS 0.014 0.001 -9999.0 0.0 -9999.0 0.0 0.0