Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.098 0.176 0.29 35.0 -9999.0 0.0 35.0 KIRREL -0.042 0.148 -9999.0 0.0 -0.459 9.0 9.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.098 0.176 -9999.0 0.0 -0.29 35.0 35.0 PLCG1 0.031 0.009 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.029 0.011 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.031 0.009 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.056 0.151 -9999.0 0.0 -0.281 19.0 19.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.049 0.125 -9999.0 0.0 -0.28 16.0 16.0 FYN -0.065 0.134 0.271 2.0 -0.264 19.0 21.0 mol:Ca2+ -0.049 0.148 -9999.0 0.0 -0.284 17.0 17.0 mol:DAG -0.048 0.149 -9999.0 0.0 -0.285 17.0 17.0 NPHS2 -0.012 0.065 -9999.0 0.0 -0.343 2.0 2.0 mol:IP3 -0.048 0.149 -9999.0 0.0 -0.285 17.0 17.0 regulation of endocytosis -0.049 0.129 -9999.0 0.0 -0.254 17.0 17.0 Nephrin/NEPH1/podocin/Cholesterol -0.063 0.144 -9999.0 0.0 -0.279 19.0 19.0 establishment of cell polarity -0.098 0.176 -9999.0 0.0 -0.29 35.0 35.0 Nephrin/NEPH1/podocin/NCK1-2 -0.039 0.148 -9999.0 0.0 -0.26 18.0 18.0 Nephrin/NEPH1/beta Arrestin2 -0.049 0.131 -9999.0 0.0 -0.256 17.0 17.0 NPHS1 -0.114 0.193 -9999.0 0.0 -0.362 30.0 30.0 Nephrin/NEPH1/podocin -0.056 0.136 -9999.0 0.0 -0.265 19.0 19.0 TJP1 0.032 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.032 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.033 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.048 0.15 -9999.0 0.0 -0.286 17.0 17.0 CD2AP 0.032 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.052 0.143 -9999.0 0.0 -0.27 18.0 18.0 GRB2 0.03 0.01 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.055 0.151 0.316 4.0 -0.269 18.0 22.0 cytoskeleton organization -0.067 0.133 -9999.0 0.0 -0.322 15.0 15.0 Nephrin/NEPH1 -0.063 0.126 -9999.0 0.0 -0.199 35.0 35.0 Nephrin/NEPH1/ZO-1 -0.064 0.15 -9999.0 0.0 -0.286 19.0 19.0