Clinical Features CN_CNMF METHLYATION_CNMF MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 5 (3%) 154 0.0018849 0.671 1 1 1 1 1 1 0.29169 1 0.68103 1 1q gain 16 (10%) 143 1.3344e-12 5.15e-10 0.69791 1 0.52536 1 0.44742 1 0.63751 1 0.80101 1 2p gain 6 (4%) 153 0.13431 1 0.0059521 1 0.18416 1 0.28493 1 0.0053733 1 0.1384 1 4p gain 4 (3%) 155 0.80569 1 0.47085 1 0.21791 1 0.37618 1 0.34792 1 0.18121 1 4q gain 3 (2%) 156 0.36106 1 0.80321 1 NA NA NA NA NA NA NA NA 5p gain 11 (7%) 148 0.079997 1 0.36749 1 0.56734 1 0.56852 1 1 1 0.90191 1 5q gain 7 (4%) 152 0.21763 1 0.0052623 1 0.15665 1 0.2267 1 0.61047 1 0.16598 1 6p gain 13 (8%) 146 0.48996 1 0.29268 1 0.91138 1 0.60924 1 0.54679 1 0.64488 1 6q gain 7 (4%) 152 0.083472 1 0.00093453 0.337 0.15665 1 0.19081 1 0.060698 1 0.16598 1 7p gain 26 (16%) 133 0.037594 1 0.11779 1 0.41044 1 0.28779 1 0.20087 1 0.17943 1 7q gain 21 (13%) 138 0.0070224 1 0.011264 1 0.37507 1 0.48662 1 0.034519 1 0.24606 1 8p gain 10 (6%) 149 0.025559 1 0.33367 1 0.3611 1 0.28614 1 0.10856 1 0.21672 1 8q gain 13 (8%) 146 0.15185 1 0.75327 1 0.30899 1 0.2528 1 0.14393 1 0.26841 1 9p gain 3 (2%) 156 0.18531 1 0.13472 1 0.40203 1 0.44136 1 0.11205 1 0.47058 1 9q gain 3 (2%) 156 0.18531 1 0.13472 1 0.40203 1 0.44136 1 0.11205 1 0.47058 1 10p gain 12 (8%) 147 0.81599 1 0.048726 1 0.81949 1 1 1 0.90709 1 0.9049 1 10q gain 10 (6%) 149 0.54217 1 0.69149 1 0.50687 1 0.71759 1 0.42252 1 0.80681 1 11p gain 4 (3%) 155 0.53399 1 0.80826 1 0.15016 1 0.13928 1 0.1837 1 0.047252 1 12p gain 11 (7%) 148 0.0072423 1 0.0084382 1 0.1817 1 0.074316 1 0.00020935 0.0779 0.032504 1 12q gain 13 (8%) 146 0.061745 1 0.10229 1 0.26274 1 0.17095 1 0.0093293 1 0.091209 1 13q gain 9 (6%) 150 0.00027865 0.103 0.021345 1 0.14152 1 0.09595 1 0.0077936 1 0.069361 1 14q gain 4 (3%) 155 0.46793 1 0.47085 1 0.8317 1 0.73088 1 0.063052 1 0.46041 1 15q gain 14 (9%) 145 0.21399 1 0.026598 1 1 1 1 1 0.59522 1 1 1 16p gain 6 (4%) 153 0.15171 1 0.55123 1 0.41172 1 1 1 0.1667 1 0.68103 1 16q gain 6 (4%) 153 0.19131 1 1 1 0.50747 1 0.56723 1 0.61047 1 0.36924 1 17q gain 4 (3%) 155 0.36875 1 0.18516 1 0.15016 1 0.6186 1 0.1837 1 0.33599 1 18p gain 8 (5%) 151 0.10017 1 0.2574 1 1 1 0.56852 1 0.075089 1 0.65119 1 18q gain 10 (6%) 149 0.089221 1 0.58501 1 1 1 0.67199 1 0.14606 1 0.6194 1 19p gain 20 (13%) 139 0.022119 1 0.07463 1 0.27388 1 0.63007 1 0.2536 1 0.65422 1 19q gain 14 (9%) 145 0.071464 1 0.007609 1 0.15128 1 0.26321 1 0.084938 1 0.23215 1 20p gain 11 (7%) 148 0.16626 1 0.19039 1 0.7347 1 0.39191 1 0.022953 1 0.45436 1 20q gain 9 (6%) 150 0.21778 1 0.03576 1 0.23591 1 0.062472 1 0.0070221 1 0.048743 1 21q gain 3 (2%) 156 0.5511 1 0.13472 1 NA NA NA NA NA NA NA NA 22q gain 3 (2%) 156 0.18531 1 0.082329 1 0.21791 1 0.37618 1 0.016343 1 0.18121 1 xq gain 5 (3%) 154 0.54125 1 0.054031 1 0.8317 1 0.28939 1 0.1667 1 0.35868 1 1p loss 96 (60%) 63 1.4576e-09 5.58e-07 0.048241 1 0.010346 1 0.013728 1 0.0008831 0.321 0.02477 1 1q loss 28 (18%) 131 0.21715 1 0.074058 1 0.91779 1 0.38701 1 0.35103 1 0.12533 1 2p loss 10 (6%) 149 0.46315 1 0.081524 1 0.4191 1 0.0028595 1 0.45367 1 0.0012058 0.433 2q loss 13 (8%) 146 0.55877 1 0.44752 1 0.6453 1 0.097416 1 0.93314 1 0.32654 1 3p loss 61 (38%) 98 2.4019e-08 9.18e-06 0.030531 1 6.9043e-05 0.026 0.00052997 0.194 0.0009177 0.332 0.011209 1 3q loss 89 (56%) 70 3.1543e-07 0.00012 0.52214 1 0.052192 1 0.00072689 0.265 0.244 1 0.011837 1 4p loss 10 (6%) 149 0.013368 1 0.23933 1 0.39636 1 0.56852 1 0.023793 1 0.65119 1 4q loss 10 (6%) 149 0.10342 1 0.23933 1 0.39636 1 0.56852 1 0.023793 1 0.65119 1 5p loss 5 (3%) 154 0.026555 1 0.30729 1 1 1 0.44136 1 0.34792 1 0.47058 1 5q loss 7 (4%) 152 0.07472 1 0.78528 1 0.45739 1 0.55672 1 0.10782 1 1 1 6q loss 19 (12%) 140 0.00041154 0.152 0.00053643 0.196 0.00044003 0.162 9.3855e-06 0.00355 0.00036744 0.136 4.7494e-06 0.0018 7q loss 6 (4%) 153 0.22133 1 0.42584 1 0.13114 1 0.058828 1 0.030598 1 0.041979 1 8p loss 19 (12%) 140 0.21849 1 0.5753 1 0.75308 1 0.64543 1 0.33994 1 0.4138 1 8q loss 12 (8%) 147 0.56402 1 0.80269 1 0.39636 1 0.26033 1 0.90232 1 0.26639 1 9p loss 12 (8%) 147 0.046769 1 0.68637 1 1 1 0.1858 1 0.24865 1 0.30602 1 9q loss 11 (7%) 148 0.043864 1 0.66338 1 0.43866 1 0.47576 1 0.41704 1 0.83253 1 11p loss 52 (33%) 107 5.8449e-12 2.25e-09 0.0010593 0.381 0.0020617 0.732 7.0767e-06 0.00268 0.00020306 0.0757 8.2625e-05 0.0311 11q loss 39 (25%) 120 4.1318e-11 1.59e-08 0.04901 1 0.030053 1 0.0064443 1 0.00018154 0.0681 0.0008791 0.32 13q loss 7 (4%) 152 0.75717 1 0.61051 1 0.49022 1 0.20341 1 0.57069 1 0.48869 1 14q loss 20 (13%) 139 0.009838 1 0.047362 1 0.36015 1 0.12464 1 0.72203 1 0.27902 1 15q loss 3 (2%) 156 0.15869 1 0.32694 1 NA NA NA NA NA NA NA NA 16p loss 8 (5%) 151 0.011767 1 0.024448 1 0.31175 1 0.34072 1 0.47897 1 0.79066 1 16q loss 4 (3%) 155 0.00019329 0.0723 0.27419 1 1 1 0.44136 1 0.34792 1 0.47058 1 17p loss 61 (38%) 98 0.035147 1 0.0025804 0.913 0.004963 1 0.017766 1 0.0080204 1 0.02344 1 17q loss 20 (13%) 139 0.010169 1 0.91867 1 0.20437 1 0.04211 1 0.024091 1 0.068177 1 18p loss 16 (10%) 143 0.78299 1 0.74423 1 0.30207 1 0.32774 1 0.49587 1 0.7074 1 18q loss 6 (4%) 153 0.4135 1 0.8765 1 0.15665 1 0.2267 1 0.2183 1 0.16598 1 19q loss 6 (4%) 153 0.017785 1 1 1 0.23634 1 0.8144 1 0.81901 1 1 1 20q loss 3 (2%) 156 0.76329 1 1 1 NA NA NA NA NA NA NA NA 21q loss 34 (21%) 125 0.098467 1 0.063857 1 0.76296 1 0.49132 1 0.6313 1 0.12587 1 22q loss 56 (35%) 103 0.026985 1 0.035845 1 0.040395 1 0.10188 1 0.0399 1 0.0074978 1 xq loss 49 (31%) 110 0.0047723 1 0.0013857 0.496 0.0086876 1 0.017566 1 0.0018405 0.657 0.0027585 0.974