Clinical Features	CN_CNMF		METHLYATION_CNMF		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
amp_1q21.3	30 (19%)	129	1.825e-18	2.88e-16	0.62054	1	1	1	0.27978	1	0.28627	1	0.4947	1
amp_4q31.1	12 (8%)	147	0.090099	1	0.08376	1	0.81949	1	0.0036898	0.446	0.19165	1	0.68899	1
amp_12q13.3	16 (10%)	143	0.037786	1	0.13178	1	0.1251	1	0.1486	1	0.0080159	0.858	0.12	1
amp_14q24.3	10 (6%)	149	0.0015482	0.203	0.1983	1	0.7588	1	0.72207	1	0.024928	1	0.59258	1
amp_17q21.31	15 (9%)	144	0.10288	1	0.82772	1	0.67512	1	0.0063211	0.714	0.37595	1	0.58345	1
del_1p36.32	101 (64%)	58	2.4592e-17	3.86e-15	0.0095096	0.989	0.10209	1	0.0035755	0.436	0.001556	0.203	0.010921	1
del_1p12	111 (70%)	48	6.6961e-13	1.04e-10	9.1739e-06	0.00136	0.00034368	0.0485	0.0045432	0.536	0.00084775	0.115	0.0042896	0.51
del_1q44	21 (13%)	138	0.077306	1	0.3321	1	1	1	0.90596	1	0.077724	1	0.25275	1
del_3p24.1	60 (38%)	99	2.9253e-09	4.48e-07	0.0035291	0.434	7.4249e-07	0.000112	9.2256e-05	0.0132	1.1896e-05	0.00175	0.00060048	0.0823
del_3q26.1	93 (58%)	66	2.4944e-08	3.79e-06	0.64669	1	0.13983	1	0.00084391	0.115	0.25067	1	0.014712	1
del_4q22.1	14 (9%)	145	0.030599	1	0.35568	1	0.22989	1	0.50702	1	0.026187	1	0.47046	1
del_4q32.3	14 (9%)	145	0.05064	1	0.1655	1	0.44012	1	0.69678	1	0.15638	1	0.16116	1
del_5q23.1	11 (7%)	148	0.0062088	0.708	0.9224	1	0.4499	1	0.1854	1	0.37297	1	0.72296	1
del_6p12.3	8 (5%)	151	0.072445	1	0.28755	1	0.19986	1	0.039155	1	0.70523	1	0.16092	1
del_6q16.1	23 (14%)	136	0.01757	1	0.061014	1	0.015682	1	0.002093	0.27	0.046942	1	0.0049781	0.577
del_8p22	24 (15%)	135	0.24153	1	0.1312	1	0.23552	1	0.16502	1	0.11907	1	0.044798	1
del_9p24.2	15 (9%)	144	0.025613	1	0.36253	1	1	1	0.01065	1	0.58518	1	0.74353	1
del_9q21.12	14 (9%)	145	0.054605	1	0.62821	1	0.29633	1	0.16706	1	0.61644	1	0.56661	1
del_11p15.4	56 (35%)	103	3.9614e-15	6.18e-13	3.0734e-05	0.00449	0.00098147	0.131	1.2972e-06	0.000195	2.4346e-06	0.000363	5.6186e-05	0.00809
del_11q22.1	44 (28%)	115	5.5615e-11	8.56e-09	0.20095	1	0.10794	1	0.011107	1	0.00057423	0.0792	0.0099492	1
del_12q21.32	3 (2%)	156	5.3321e-05	0.00773	0.43822	1	NA	NA	NA	NA	NA	NA	NA	NA
del_16q21	5 (3%)	154	0.00038962	0.0545	0.11527	1	0.52392	1	0.28939	1	0.29169	1	0.35868	1
del_17p13.2	64 (40%)	95	0.020485	1	0.00046064	0.064	0.0013081	0.173	0.0075398	0.822	0.0058855	0.677	0.013289	1
del_17q11.2	42 (26%)	117	0.11675	1	0.003493	0.433	0.0021416	0.274	0.0032797	0.41	0.00016971	0.0241	0.0021461	0.274
del_22q12.3	59 (37%)	100	0.037571	1	0.0088772	0.932	0.0077271	0.835	0.019512	1	0.0081511	0.864	0.00093094	0.125
del_22q13.31	64 (40%)	95	0.024858	1	0.01092	1	0.016392	1	0.035526	1	0.013444	1	0.0030002	0.378
del_xp21.1	46 (29%)	113	0.0067735	0.759	0.0070563	0.783	0.0036825	0.446	0.045601	1	0.0045988	0.538	0.0073031	0.803