		Clinical Features	CN_CNMF		METHLYATION_CNMF		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	5 (3%)	154	0.0018849	0.671	1	1	1	1	1	1	0.29169	1	0.68103	1
1q gain	16 (10%)	143	1.3344e-12	5.15e-10	0.69791	1	0.52536	1	0.44742	1	0.63751	1	0.80101	1
2p gain	6 (4%)	153	0.13431	1	0.0059521	1	0.18416	1	0.28493	1	0.0053733	1	0.1384	1
4p gain	4 (3%)	155	0.80569	1	0.47085	1	0.21791	1	0.37618	1	0.34792	1	0.18121	1
4q gain	3 (2%)	156	0.36106	1	0.80321	1	NA	NA	NA	NA	NA	NA	NA	NA
5p gain	11 (7%)	148	0.079997	1	0.36749	1	0.56734	1	0.56852	1	1	1	0.90191	1
5q gain	7 (4%)	152	0.21763	1	0.0052623	1	0.15665	1	0.2267	1	0.61047	1	0.16598	1
6p gain	13 (8%)	146	0.48996	1	0.29268	1	0.91138	1	0.60924	1	0.54679	1	0.64488	1
6q gain	7 (4%)	152	0.083472	1	0.00093453	0.337	0.15665	1	0.19081	1	0.060698	1	0.16598	1
7p gain	26 (16%)	133	0.037594	1	0.11779	1	0.41044	1	0.28779	1	0.20087	1	0.17943	1
7q gain	21 (13%)	138	0.0070224	1	0.011264	1	0.37507	1	0.48662	1	0.034519	1	0.24606	1
8p gain	10 (6%)	149	0.025559	1	0.33367	1	0.3611	1	0.28614	1	0.10856	1	0.21672	1
8q gain	13 (8%)	146	0.15185	1	0.75327	1	0.30899	1	0.2528	1	0.14393	1	0.26841	1
9p gain	3 (2%)	156	0.18531	1	0.13472	1	0.40203	1	0.44136	1	0.11205	1	0.47058	1
9q gain	3 (2%)	156	0.18531	1	0.13472	1	0.40203	1	0.44136	1	0.11205	1	0.47058	1
10p gain	12 (8%)	147	0.81599	1	0.048726	1	0.81949	1	1	1	0.90709	1	0.9049	1
10q gain	10 (6%)	149	0.54217	1	0.69149	1	0.50687	1	0.71759	1	0.42252	1	0.80681	1
11p gain	4 (3%)	155	0.53399	1	0.80826	1	0.15016	1	0.13928	1	0.1837	1	0.047252	1
12p gain	11 (7%)	148	0.0072423	1	0.0084382	1	0.1817	1	0.074316	1	0.00020935	0.0779	0.032504	1
12q gain	13 (8%)	146	0.061745	1	0.10229	1	0.26274	1	0.17095	1	0.0093293	1	0.091209	1
13q gain	9 (6%)	150	0.00027865	0.103	0.021345	1	0.14152	1	0.09595	1	0.0077936	1	0.069361	1
14q gain	4 (3%)	155	0.46793	1	0.47085	1	0.8317	1	0.73088	1	0.063052	1	0.46041	1
15q gain	14 (9%)	145	0.21399	1	0.026598	1	1	1	1	1	0.59522	1	1	1
16p gain	6 (4%)	153	0.15171	1	0.55123	1	0.41172	1	1	1	0.1667	1	0.68103	1
16q gain	6 (4%)	153	0.19131	1	1	1	0.50747	1	0.56723	1	0.61047	1	0.36924	1
17q gain	4 (3%)	155	0.36875	1	0.18516	1	0.15016	1	0.6186	1	0.1837	1	0.33599	1
18p gain	8 (5%)	151	0.10017	1	0.2574	1	1	1	0.56852	1	0.075089	1	0.65119	1
18q gain	10 (6%)	149	0.089221	1	0.58501	1	1	1	0.67199	1	0.14606	1	0.6194	1
19p gain	20 (13%)	139	0.022119	1	0.07463	1	0.27388	1	0.63007	1	0.2536	1	0.65422	1
19q gain	14 (9%)	145	0.071464	1	0.007609	1	0.15128	1	0.26321	1	0.084938	1	0.23215	1
20p gain	11 (7%)	148	0.16626	1	0.19039	1	0.7347	1	0.39191	1	0.022953	1	0.45436	1
20q gain	9 (6%)	150	0.21778	1	0.03576	1	0.23591	1	0.062472	1	0.0070221	1	0.048743	1
21q gain	3 (2%)	156	0.5511	1	0.13472	1	NA	NA	NA	NA	NA	NA	NA	NA
22q gain	3 (2%)	156	0.18531	1	0.082329	1	0.21791	1	0.37618	1	0.016343	1	0.18121	1
xq gain	5 (3%)	154	0.54125	1	0.054031	1	0.8317	1	0.28939	1	0.1667	1	0.35868	1
1p loss	96 (60%)	63	1.4576e-09	5.58e-07	0.048241	1	0.010346	1	0.013728	1	0.0008831	0.321	0.02477	1
1q loss	28 (18%)	131	0.21715	1	0.074058	1	0.91779	1	0.38701	1	0.35103	1	0.12533	1
2p loss	10 (6%)	149	0.46315	1	0.081524	1	0.4191	1	0.0028595	1	0.45367	1	0.0012058	0.433
2q loss	13 (8%)	146	0.55877	1	0.44752	1	0.6453	1	0.097416	1	0.93314	1	0.32654	1
3p loss	61 (38%)	98	2.4019e-08	9.18e-06	0.030531	1	6.9043e-05	0.026	0.00052997	0.194	0.0009177	0.332	0.011209	1
3q loss	89 (56%)	70	3.1543e-07	0.00012	0.52214	1	0.052192	1	0.00072689	0.265	0.244	1	0.011837	1
4p loss	10 (6%)	149	0.013368	1	0.23933	1	0.39636	1	0.56852	1	0.023793	1	0.65119	1
4q loss	10 (6%)	149	0.10342	1	0.23933	1	0.39636	1	0.56852	1	0.023793	1	0.65119	1
5p loss	5 (3%)	154	0.026555	1	0.30729	1	1	1	0.44136	1	0.34792	1	0.47058	1
5q loss	7 (4%)	152	0.07472	1	0.78528	1	0.45739	1	0.55672	1	0.10782	1	1	1
6q loss	19 (12%)	140	0.00041154	0.152	0.00053643	0.196	0.00044003	0.162	9.3855e-06	0.00355	0.00036744	0.136	4.7494e-06	0.0018
7q loss	6 (4%)	153	0.22133	1	0.42584	1	0.13114	1	0.058828	1	0.030598	1	0.041979	1
8p loss	19 (12%)	140	0.21849	1	0.5753	1	0.75308	1	0.64543	1	0.33994	1	0.4138	1
8q loss	12 (8%)	147	0.56402	1	0.80269	1	0.39636	1	0.26033	1	0.90232	1	0.26639	1
9p loss	12 (8%)	147	0.046769	1	0.68637	1	1	1	0.1858	1	0.24865	1	0.30602	1
9q loss	11 (7%)	148	0.043864	1	0.66338	1	0.43866	1	0.47576	1	0.41704	1	0.83253	1
11p loss	52 (33%)	107	5.8449e-12	2.25e-09	0.0010593	0.381	0.0020617	0.732	7.0767e-06	0.00268	0.00020306	0.0757	8.2625e-05	0.0311
11q loss	39 (25%)	120	4.1318e-11	1.59e-08	0.04901	1	0.030053	1	0.0064443	1	0.00018154	0.0681	0.0008791	0.32
13q loss	7 (4%)	152	0.75717	1	0.61051	1	0.49022	1	0.20341	1	0.57069	1	0.48869	1
14q loss	20 (13%)	139	0.009838	1	0.047362	1	0.36015	1	0.12464	1	0.72203	1	0.27902	1
15q loss	3 (2%)	156	0.15869	1	0.32694	1	NA	NA	NA	NA	NA	NA	NA	NA
16p loss	8 (5%)	151	0.011767	1	0.024448	1	0.31175	1	0.34072	1	0.47897	1	0.79066	1
16q loss	4 (3%)	155	0.00019329	0.0723	0.27419	1	1	1	0.44136	1	0.34792	1	0.47058	1
17p loss	61 (38%)	98	0.035147	1	0.0025804	0.913	0.004963	1	0.017766	1	0.0080204	1	0.02344	1
17q loss	20 (13%)	139	0.010169	1	0.91867	1	0.20437	1	0.04211	1	0.024091	1	0.068177	1
18p loss	16 (10%)	143	0.78299	1	0.74423	1	0.30207	1	0.32774	1	0.49587	1	0.7074	1
18q loss	6 (4%)	153	0.4135	1	0.8765	1	0.15665	1	0.2267	1	0.2183	1	0.16598	1
19q loss	6 (4%)	153	0.017785	1	1	1	0.23634	1	0.8144	1	0.81901	1	1	1
20q loss	3 (2%)	156	0.76329	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA
21q loss	34 (21%)	125	0.098467	1	0.063857	1	0.76296	1	0.49132	1	0.6313	1	0.12587	1
22q loss	56 (35%)	103	0.026985	1	0.035845	1	0.040395	1	0.10188	1	0.0399	1	0.0074978	1
xq loss	49 (31%)	110	0.0047723	1	0.0013857	0.496	0.0086876	1	0.017566	1	0.0018405	0.657	0.0027585	0.974
