Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.074 0.154 0.333 85.0 -9999.0 0.0 85.0 KIRREL -0.095 0.195 -9999.0 0.0 -0.45 77.0 77.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.074 0.154 -9999.0 0.0 -0.333 85.0 85.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.044 0.117 -9999.0 0.0 -0.344 11.0 11.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.034 0.108 -9999.0 0.0 -0.418 3.0 3.0 FYN -0.046 0.109 -9999.0 0.0 -0.309 11.0 11.0 mol:Ca2+ -0.044 0.116 -9999.0 0.0 -0.341 11.0 11.0 mol:DAG -0.044 0.116 -9999.0 0.0 -0.343 11.0 11.0 NPHS2 -0.012 0.051 -9999.0 0.0 -0.61 2.0 2.0 mol:IP3 -0.044 0.116 -9999.0 0.0 -0.343 11.0 11.0 regulation of endocytosis -0.035 0.104 -9999.0 0.0 -0.469 2.0 2.0 Nephrin/NEPH1/podocin/Cholesterol -0.053 0.116 -9999.0 0.0 -0.245 84.0 84.0 establishment of cell polarity -0.074 0.154 -9999.0 0.0 -0.333 85.0 85.0 Nephrin/NEPH1/podocin/NCK1-2 -0.032 0.11 -9999.0 0.0 -0.5 3.0 3.0 Nephrin/NEPH1/beta Arrestin2 -0.034 0.105 -9999.0 0.0 -0.475 2.0 2.0 NPHS1 -0.019 0.097 -9999.0 0.0 -0.591 9.0 9.0 Nephrin/NEPH1/podocin -0.046 0.11 -9999.0 0.0 -0.311 11.0 11.0 TJP1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.033 -9999.0 0.0 -0.592 1.0 1.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.044 0.117 -9999.0 0.0 -0.344 11.0 11.0 CD2AP 0.014 0.001 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.044 0.117 -9999.0 0.0 -0.344 11.0 11.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.077 0.154 -9999.0 0.0 -0.4 42.0 42.0 cytoskeleton organization -0.035 0.117 -9999.0 0.0 -0.454 3.0 3.0 Nephrin/NEPH1 -0.05 0.108 -9999.0 0.0 -0.23 85.0 85.0 Nephrin/NEPH1/ZO-1 -0.048 0.123 -9999.0 0.0 -0.263 57.0 57.0