Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.038 0.18 0.454 1.0 -0.435 38.0 39.0 MAP3K8 0.019 0.052 0.171 2.0 -0.3 8.0 10.0 FOS -0.032 0.143 0.505 1.0 -0.359 35.0 36.0 PRKCA 0.007 0.065 -9999.0 0.0 -0.3 13.0 13.0 PTPN7 0.025 0.036 0.172 13.0 -9999.0 0.0 13.0 HRAS 0.029 0.018 0.17 5.0 -9999.0 0.0 5.0 PRKCB -0.044 0.131 -9999.0 0.0 -0.301 67.0 67.0 NRAS 0.025 0.019 -9999.0 0.0 -0.302 1.0 1.0 RAS family/GTP 0.041 0.031 -9999.0 0.0 -0.171 1.0 1.0 MAPK3 -0.008 0.096 -9999.0 0.0 -0.442 5.0 5.0 MAP2K1 -0.071 0.194 -9999.0 0.0 -0.415 66.0 66.0 ELK1 0.019 0.022 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.053 0.166 -9999.0 0.0 -0.398 53.0 53.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.004 53.0 53.0 MAPK1 -0.011 0.105 -9999.0 0.0 -0.491 7.0 7.0 RAF1 -0.065 0.176 -9999.0 0.0 -0.385 66.0 66.0 KRAS 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0