		Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
amp_1p32.1	55 (37%)	95	1.3211e-06	0.000584	9.8683e-07	0.000438	0.88744	1	0.21877	1	0.016987	1	0.002689	0.941	0.059553	1	0.0083402	1
amp_1q24.3	65 (43%)	85	5.8352e-05	0.0243	0.0048245	1	0.74713	1	0.28042	1	0.26836	1	0.1542	1	0.14207	1	0.30493	1
amp_3p11.2	36 (24%)	114	0.01041	1	0.098327	1	0.62743	1	1	1	0.60832	1	0.40714	1	0.26762	1	0.69185	1
amp_5p15.33	67 (45%)	83	0.00062899	0.245	0.025817	1	0.23684	1	0.3856	1	0.27317	1	0.11313	1	0.17795	1	0.21153	1
amp_6p21.1	36 (24%)	114	4.816e-05	0.0202	7.3148e-05	0.0304	0.0015023	0.554	0.0012891	0.482	0.017732	1	0.0015	0.554	0.0082461	1	0.0064287	1
amp_6q24.3	47 (31%)	103	0.0029059	1	2.0579e-05	0.00883	0.00021766	0.0882	9.5353e-06	0.00413	2.3582e-05	0.01	2.7432e-05	0.0117	1.1126e-05	0.00481	0.00014204	0.058
amp_7q31.1	44 (29%)	106	0.00082482	0.318	0.037922	1	0.4944	1	0.05785	1	0.070655	1	0.040531	1	0.01538	1	0.11508	1
amp_8q21.12	54 (36%)	96	0.019915	1	0.032309	1	0.85156	1	0.57699	1	0.80701	1	0.87252	1	0.84295	1	0.87252	1
amp_11q22.2	25 (17%)	125	0.22643	1	0.098006	1	0.048535	1	0.049924	1	0.057806	1	0.064921	1	0.076158	1	0.064921	1
amp_12p13.32	28 (19%)	122	0.29084	1	0.59435	1	0.30211	1	0.078496	1	0.086021	1	0.28424	1	0.12152	1	0.12879	1
amp_12q15	58 (39%)	92	3.9434e-17	1.83e-14	8.6662e-10	3.94e-07	5.1673e-10	2.36e-07	3.4663e-13	1.6e-10	2.8779e-10	1.32e-07	1.032e-11	4.77e-09	5.5348e-11	2.55e-08	1.032e-11	4.77e-09
amp_13q34	28 (19%)	122	0.0015842	0.581	0.0016209	0.593	0.21173	1	0.39095	1	0.7356	1	1	1	0.8428	1	0.78884	1
amp_17p11.2	60 (40%)	90	1.731e-07	7.77e-05	0.017429	1	0.45598	1	0.31925	1	1	1	1	1	0.84137	1	1	1
amp_17q24.3	45 (30%)	105	0.085028	1	0.00016156	0.0658	0.0050453	1	0.49961	1	0.035291	1	0.0012117	0.456	0.06706	1	0.003581	1
amp_19p13.2	60 (40%)	90	4.1248e-05	0.0174	0.52696	1	1	1	0.42763	1	0.65858	1	0.56211	1	0.89184	1	0.56211	1
amp_19q12	53 (35%)	97	1.088e-06	0.000482	0.0014349	0.532	0.77717	1	0.063849	1	0.39136	1	0.22802	1	0.53914	1	0.22802	1
amp_20q13.33	62 (41%)	88	0.0013561	0.506	0.0085959	1	0.25262	1	0.0087669	1	0.010269	1	0.073568	1	0.011237	1	0.030184	1
amp_21q21.1	48 (32%)	102	4.3611e-05	0.0184	0.0008889	0.342	0.76337	1	0.27104	1	0.19086	1	0.26839	1	0.16448	1	0.26839	1
amp_xp21.1	52 (35%)	98	2.2972e-06	0.00101	0.027333	1	1	1	0.45131	1	0.91314	1	0.78775	1	0.88167	1	1	1
amp_xq21.2	24 (16%)	126	0.0039446	1	0.017939	1	0.19084	1	0.61642	1	0.34926	1	0.33439	1	0.38176	1	0.33439	1
del_1p36.32	46 (31%)	104	0.028057	1	1.353e-06	0.000597	2.7673e-05	0.0117	4.5642e-06	0.00199	1.9956e-06	0.000878	3.4838e-09	1.58e-06	6.1899e-07	0.000277	3.4838e-09	1.58e-06
del_1p32.3	26 (17%)	124	0.31492	1	0.14535	1	0.048012	1	1	1	0.75233	1	0.040033	1	0.75703	1	0.040033	1
del_1q44	47 (31%)	103	1.1902e-05	0.00513	0.0078586	1	0.41992	1	0.062503	1	0.077024	1	0.065792	1	0.12937	1	0.18257	1
del_2p25.3	52 (35%)	98	0.0020671	0.738	2.2907e-05	0.00978	0.00031656	0.127	4.7892e-06	0.00208	0.0017631	0.642	8.8127e-05	0.0363	0.0028252	0.983	8.8127e-05	0.0363
del_2q37.3	63 (42%)	87	2.6159e-08	1.18e-05	0.027756	1	0.066396	1	0.46691	1	0.70525	1	0.75087	1	0.63918	1	0.75087	1
del_2q37.3	65 (43%)	85	1.2064e-08	5.44e-06	0.0083014	1	0.013369	1	0.21638	1	0.87158	1	1	1	0.8591	1	1	1
del_3p21.31	33 (22%)	117	0.012043	1	0.0001904	0.0773	0.0019355	0.695	0.00034285	0.136	0.0089044	1	0.015231	1	0.0050531	1	0.0040931	1
del_3q29	35 (23%)	115	0.005923	1	0.0023721	0.835	0.055104	1	0.16092	1	0.28003	1	0.21352	1	0.32553	1	0.21352	1
del_4q35.1	56 (37%)	94	1.3046e-05	0.00561	0.20747	1	0.057037	1	0.76615	1	0.7292	1	0.67506	1	0.61132	1	0.67506	1
del_6p25.1	52 (35%)	98	0.37647	1	0.044822	1	0.042109	1	0.010594	1	0.1067	1	0.23329	1	0.11715	1	0.23329	1
del_6q14.1	43 (29%)	107	0.00057383	0.226	0.038926	1	0.42022	1	0.74932	1	0.23014	1	0.23658	1	0.28181	1	0.15856	1
del_7q36.3	38 (25%)	112	0.0011928	0.451	0.20875	1	0.82149	1	0.61133	1	0.39729	1	0.42985	1	0.78162	1	0.42985	1
del_8p23.3	44 (29%)	106	0.082247	1	0.0021161	0.751	0.18794	1	0.09877	1	0.0048718	1	0.0050311	1	0.0026762	0.939	0.0017886	0.647
del_9p24.3	58 (39%)	92	0.00026607	0.107	0.028284	1	0.17196	1	0.0011425	0.435	0.0028866	1	0.00034088	0.136	0.0020957	0.746	0.0011329	0.433
del_9p21.3	63 (42%)	87	0.00040034	0.159	0.0086637	1	0.32849	1	0.0039798	1	0.01019	1	0.0036308	1	0.0016397	0.598	0.0094253	1
del_9q34.3	42 (28%)	108	0.0043573	1	0.097645	1	0.0050943	1	0.15642	1	0.17617	1	0.10057	1	0.13376	1	0.10057	1
del_10p15.3	76 (51%)	74	0.0080861	1	0.0006895	0.268	0.046273	1	0.13818	1	0.95899	1	0.62012	1	0.86311	1	0.62012	1
del_10q23.31	84 (56%)	66	6.1403e-10	2.8e-07	3.4972e-10	1.6e-07	3.7596e-09	1.7e-06	3.2982e-07	0.000148	0.0017633	0.642	0.00060553	0.237	0.0014834	0.549	0.00060553	0.237
del_11p15.5	67 (45%)	83	4.7887e-05	0.0201	0.0012056	0.455	0.2981	1	0.22221	1	0.85173	1	0.89625	1	0.77089	1	1	1
del_11q24.3	65 (43%)	85	2.4295e-06	0.00106	0.0030502	1	0.35923	1	0.012946	1	0.0034611	1	0.0053239	1	0.0071876	1	0.014354	1
del_12p13.1	52 (35%)	98	5.8899e-05	0.0245	7.3225e-05	0.0304	0.28077	1	0.26881	1	0.046834	1	0.031537	1	0.081859	1	0.031537	1
del_12q12	29 (19%)	121	0.099896	1	0.064213	1	0.20265	1	0.5848	1	0.47775	1	1	1	0.51439	1	1	1
del_13q14.2	106 (71%)	44	6.3264e-07	0.000282	7.1524e-07	0.000318	2.0837e-05	0.00892	4.3655e-06	0.0019	0.013814	1	0.014053	1	0.0080463	1	0.014053	1
del_14q24.1	51 (34%)	99	0.68045	1	0.010528	1	0.0010404	0.398	0.26764	1	0.56628	1	0.15637	1	0.53423	1	0.27469	1
del_15q11.2	30 (20%)	120	0.45315	1	0.20583	1	0.075243	1	0.13473	1	0.11165	1	0.10823	1	0.061087	1	0.10823	1
del_16q12.1	83 (55%)	67	4.9313e-05	0.0206	0.00040565	0.161	0.045725	1	0.0055597	1	0.04715	1	0.0058589	1	0.039941	1	0.0058589	1
del_17p13.1	71 (47%)	79	0.00043982	0.174	0.00096138	0.369	3.3437e-05	0.0141	0.00026318	0.106	0.068423	1	0.051795	1	0.030284	1	0.051795	1
del_17q11.2	45 (30%)	105	3.5027e-06	0.00153	0.00012046	0.0494	0.13864	1	0.17903	1	0.0023447	0.828	0.00069602	0.269	0.0012672	0.475	0.0027026	0.943
del_17q25.3	40 (27%)	110	0.0051522	1	0.057322	1	0.33518	1	0.078019	1	0.35711	1	0.19164	1	0.27332	1	0.31732	1
del_18q23	50 (33%)	100	0.059315	1	0.031189	1	0.63154	1	0.13654	1	0.04087	1	0.29119	1	0.051351	1	0.42891	1
del_19p13.3	45 (30%)	105	0.001411	0.525	7.9329e-05	0.0328	0.0073613	1	0.021608	1	0.021274	1	0.031003	1	0.01487	1	0.031003	1
del_19q13.43	63 (42%)	87	0.0060106	1	0.0044325	1	0.16577	1	0.0769	1	0.053312	1	0.081549	1	0.10395	1	0.081549	1
del_21q11.2	28 (19%)	122	0.3826	1	0.25706	1	0.56468	1	0.2973	1	0.055024	1	0.15317	1	0.13741	1	0.15317	1
del_21q22.3	39 (26%)	111	0.05198	1	0.049993	1	0.87493	1	0.26932	1	0.55192	1	0.80362	1	0.44195	1	0.80362	1
del_22q13.31	53 (35%)	97	0.00033009	0.132	0.022147	1	0.0022468	0.795	0.38766	1	0.49093	1	0.32369	1	0.54455	1	0.32369	1
del_xp22.32	47 (31%)	103	0.097901	1	0.0019608	0.702	0.017137	1	0.021864	1	0.059378	1	0.025438	1	0.031239	1	0.025438	1
del_xq21.1	72 (48%)	78	0.10636	1	0.00013046	0.0534	0.013742	1	0.0031563	1	0.009212	1	0.0018082	0.653	0.010883	1	0.0018082	0.653
del_xq27.1	74 (49%)	76	0.0006109	0.238	0.00030267	0.122	0.040321	1	0.00050969	0.201	0.0060658	1	0.001153	0.438	0.005531	1	0.001153	0.438
