Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.021 0.1 0.217 48.0 -9999.0 0.0 48.0 KIRREL 0.002 0.052 -9999.0 0.0 -0.293 5.0 5.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.021 0.1 -9999.0 0.0 -0.217 48.0 48.0 PLCG1 0.024 0.01 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.019 0.121 -9999.0 0.0 -0.217 55.0 55.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.033 0.094 -9999.0 0.0 -0.213 50.0 50.0 FYN -0.037 0.108 0.218 11.0 -0.208 54.0 65.0 mol:Ca2+ -0.02 0.114 -9999.0 0.0 -0.216 49.0 49.0 mol:DAG -0.019 0.115 -9999.0 0.0 -0.217 49.0 49.0 NPHS2 -0.058 0.154 -9999.0 0.0 -0.379 50.0 50.0 mol:IP3 -0.019 0.115 -9999.0 0.0 -0.217 49.0 49.0 regulation of endocytosis -0.021 0.105 -9999.0 0.0 -0.196 54.0 54.0 Nephrin/NEPH1/podocin/Cholesterol -0.029 0.114 -9999.0 0.0 -0.186 86.0 86.0 establishment of cell polarity -0.021 0.1 -9999.0 0.0 -0.217 48.0 48.0 Nephrin/NEPH1/podocin/NCK1-2 -0.007 0.118 -9999.0 0.0 -0.253 14.0 14.0 Nephrin/NEPH1/beta Arrestin2 -0.02 0.107 -9999.0 0.0 -0.198 54.0 54.0 NPHS1 -0.041 0.121 -9999.0 0.0 -0.291 49.0 49.0 Nephrin/NEPH1/podocin -0.025 0.109 -9999.0 0.0 -0.207 56.0 56.0 TJP1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.019 0.115 -9999.0 0.0 -0.218 49.0 49.0 CD2AP 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.019 0.122 -9999.0 0.0 -0.218 55.0 55.0 GRB2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.041 0.107 0.218 12.0 -0.202 53.0 65.0 cytoskeleton organization -0.046 0.102 0.206 2.0 -0.236 50.0 52.0 Nephrin/NEPH1 -0.009 0.069 -9999.0 0.0 -0.144 48.0 48.0 Nephrin/NEPH1/ZO-1 -0.003 0.087 -9999.0 0.0 -0.218 15.0 15.0