Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
amp_1q22	42 (75%)	14	0.89639	1	0.21288	1	0.4754	1	0.15051	1	0.17946	1	0.35595	1	0.24068	1	0.10939	1
amp_2p14	28 (50%)	28	0.50642	1	0.025005	1	0.0074472	1	0.063119	1	0.46329	1	0.1078	1	0.35928	1	0.18015	1
amp_2q13	29 (52%)	27	0.35752	1	0.016461	1	0.047735	1	0.070571	1	1	1	0.45892	1	0.80907	1	0.63959	1
amp_3p25.1	20 (36%)	36	0.02856	1	0.46678	1	0.28874	1	0.59688	1	0.2188	1	0.012238	1	0.43983	1	0.048643	1
amp_3q26.2	37 (66%)	19	0.0012638	0.621	0.0093978	1	0.089862	1	0.084772	1	0.34237	1	0.48042	1	0.7044	1	0.27738	1
amp_4p16.3	25 (45%)	31	0.025987	1	0.14019	1	0.38016	1	0.37655	1	0.95464	1	0.34101	1	0.85424	1	0.26324	1
amp_5p13.2	26 (46%)	30	0.060289	1	0.54797	1	0.23823	1	0.47463	1	0.91268	1	0.44638	1	0.93162	1	1	1
amp_6p24.2	37 (66%)	19	0.10509	1	0.96737	1	0.66521	1	0.42861	1	0.85158	1	0.26407	1	0.8426	1	0.50973	1
amp_8p11.21	33 (59%)	23	0.35908	1	0.60047	1	0.65109	1	0.19761	1	0.61038	1	0.76518	1	0.75825	1	1	1
amp_8q11.23	38 (68%)	18	0.14243	1	0.20663	1	0.19706	1	0.12152	1	0.75359	1	1	1	0.7044	1	0.77896	1
amp_8q24.21	42 (75%)	14	0.039873	1	0.72229	1	0.18916	1	0.29872	1	0.040839	1	0.033903	1	0.017575	1	0.0081929	1
amp_8q24.21	40 (71%)	16	0.0068589	1	0.32837	1	0.076166	1	0.10286	1	0.048477	1	0.043509	1	0.017699	1	0.0096097	1
amp_10q22.2	26 (46%)	30	0.23227	1	0.47023	1	0.96095	1	1	1	0.69568	1	0.30648	1	0.60941	1	0.51291	1
amp_11q13.1	19 (34%)	37	0.43984	1	0.60632	1	0.33233	1	0.35955	1	0.71435	1	0.67769	1	0.65522	1	1	1
amp_12q12	22 (39%)	34	0.15002	1	0.093247	1	0.25502	1	0.42128	1	0.86561	1	0.82998	1	0.66712	1	1	1
amp_12q15	17 (30%)	39	0.42402	1	0.3651	1	0.25433	1	0.77365	1	0.80246	1	0.50884	1	0.52587	1	0.72311	1
amp_13q31.3	25 (45%)	31	0.39559	1	0.41535	1	0.13402	1	0.078817	1	0.085266	1	0.0021385	1	0.031055	1	0.0068971	1
amp_16p11.2	20 (36%)	36	0.004788	1	0.2813	1	0.66344	1	0.13807	1	0.73559	1	0.54614	1	0.3793	1	0.54504	1
amp_17q12	27 (48%)	29	0.92604	1	0.17702	1	0.31312	1	0.43289	1	0.34603	1	0.83906	1	0.58109	1	0.56536	1
amp_17q25.1	32 (57%)	24	0.62624	1	0.012854	1	0.60545	1	0.26884	1	0.66623	1	0.3753	1	0.47539	1	0.49449	1
amp_19p13.2	19 (34%)	37	0.33766	1	0.24825	1	0.79735	1	0.75329	1	0.33083	1	0.26407	1	0.21996	1	0.11631	1
amp_19q12	45 (80%)	11	0.00064334	0.318	0.00018975	0.0941	0.19338	1	0.044235	1	0.64232	1	0.31998	1	0.44255	1	0.43502	1
amp_20q11.21	48 (86%)	8	0.014471	1	0.18587	1	0.54502	1	0.12758	1	0.16097	1	0.033815	1	0.12985	1	0.11053	1
amp_20q11.21	48 (86%)	8	0.15459	1	0.26345	1	0.19469	1	0.25784	1	0.17855	1	0.26118	1	0.14843	1	0.36946	1
amp_xp11.21	28 (50%)	28	0.2475	1	0.54273	1	0.048132	1	0.071876	1	0.028659	1	0.0068862	1	0.078944	1	0.015033	1
del_1p36.21	19 (34%)	37	0.083192	1	0.37943	1	0.33669	1	0.46698	1	0.1356	1	0.0080167	1	0.12344	1	0.0083003	1
del_2q22.1	11 (20%)	45	0.50165	1	0.50692	1	0.52725	1	0.37173	1	0.55156	1	0.21074	1	0.28233	1	0.14235	1
del_3p21.1	37 (66%)	19	0.43096	1	0.41757	1	0.46699	1	0.39853	1	0.50415	1	1	1	0.49747	1	0.62376	1
del_3p14.1	30 (54%)	26	1	1	0.63665	1	0.17298	1	0.35865	1	0.08895	1	0.77459	1	0.20737	1	0.45522	1
del_3q13.31	19 (34%)	37	0.11192	1	0.11812	1	0.92266	1	1	1	0.93966	1	0.38675	1	0.67162	1	0.38342	1
del_4q22.1	37 (66%)	19	0.061904	1	0.048556	1	0.025293	1	0.044171	1	0.014048	1	0.299	1	0.028813	1	0.08167	1
del_4q34.3	37 (66%)	19	0.0037868	1	0.018532	1	0.011166	1	0.044171	1	0.0041209	1	0.62106	1	0.0095587	1	0.30035	1
del_5q11.2	26 (46%)	30	0.13344	1	0.097119	1	0.59663	1	0.12924	1	0.54085	1	0.44638	1	0.081573	1	1	1
del_6q26	10 (18%)	46	0.52756	1	0.5194	1	0.12185	1	0.75081	1	0.32883	1	0.19607	1	0.17431	1	0.25224	1
del_7q11.22	12 (21%)	44	0.26198	1	0.43978	1	0.75995	1	0.81258	1	0.8608	1	0.68408	1	0.80813	1	1	1
del_7q36.2	20 (36%)	36	0.15614	1	0.17126	1	0.48346	1	0.47305	1	0.37225	1	0.056965	1	0.52782	1	0.17474	1
del_8p21.3	32 (57%)	24	0.00066445	0.328	0.45527	1	0.25141	1	0.28593	1	0.78912	1	0.3753	1	0.421	1	0.82462	1
del_9p23	34 (61%)	22	0.09194	1	0.13537	1	0.61867	1	0.62368	1	0.48184	1	0.14604	1	0.83889	1	0.5906	1
del_9q21.13	39 (70%)	17	0.1117	1	0.3062	1	0.21147	1	0.3816	1	0.46742	1	0.51331	1	0.65443	1	0.53178	1
del_9q33.3	38 (68%)	18	0.44247	1	0.10969	1	0.087996	1	0.29388	1	1	1	0.73309	1	0.78478	1	1	1
del_10q21.1	18 (32%)	38	0.50466	1	0.39186	1	0.60085	1	0.53765	1	0.44913	1	0.299	1	0.30223	1	0.30035	1
del_10q23.31	20 (36%)	36	0.14299	1	0.12553	1	0.1193	1	0.19129	1	0.73559	1	1	1	0.58109	1	0.66578	1
del_11p15.5	25 (45%)	31	0.19207	1	0.73909	1	0.88399	1	0.95135	1	0.69568	1	0.76095	1	0.23484	1	0.51291	1
del_11q14.1	26 (46%)	30	0.61615	1	0.20182	1	1	1	1	1	0.25931	1	0.18615	1	0.25079	1	0.30937	1
del_11q24.2	27 (48%)	29	0.57991	1	0.034279	1	0.13422	1	0.69601	1	0.2462	1	0.28566	1	0.23615	1	0.42398	1
del_12q23.1	20 (36%)	36	0.64048	1	0.87823	1	0.66344	1	0.45442	1	0.92163	1	0.052418	1	0.91171	1	0.30763	1
del_12q24.31	20 (36%)	36	0.7741	1	0.82597	1	0.15334	1	0.49163	1	0.57735	1	0.15114	1	0.15184	1	0.30763	1
del_13q12.11	30 (54%)	26	0.42817	1	0.018355	1	0.36578	1	0.31368	1	0.69568	1	0.11192	1	0.47846	1	0.21148	1
del_13q14.2	32 (57%)	24	0.57546	1	0.00079605	0.392	0.013498	1	0.034672	1	0.45743	1	0.12401	1	0.13366	1	0.029318	1
del_14q21.1	28 (50%)	28	0.73171	1	0.05387	1	0.060777	1	0.11713	1	0.37283	1	0.40498	1	0.34249	1	0.542	1
del_15q15.1	43 (77%)	13	0.040289	1	0.036684	1	0.34791	1	0.37812	1	0.11198	1	1	1	0.048143	1	0.757	1
del_16p13.3	33 (59%)	23	0.17548	1	0.52743	1	0.56164	1	0.42882	1	0.33877	1	1	1	0.58457	1	1	1
del_16q23.1	39 (70%)	17	0.15225	1	0.39635	1	0.39544	1	0.30547	1	0.85975	1	1	1	0.45106	1	0.65187	1
del_17p13.1	42 (75%)	14	0.062886	1	0.058642	1	0.058053	1	0.11264	1	0.13173	1	0.44307	1	0.060029	1	0.3934	1
del_17q21.32	19 (34%)	37	0.89868	1	0.75314	1	0.18173	1	0.030101	1	0.21466	1	0.74473	1	0.19696	1	0.54759	1
del_18q22.2	26 (46%)	30	0.11972	1	0.34104	1	0.47233	1	0.31368	1	0.023133	1	0.01533	1	0.088745	1	0.0074617	1
del_19p13.3	47 (84%)	9	0.14029	1	0.027946	1	0.098426	1	0.16431	1	0.014915	1	0.033815	1	0.0082842	1	0.11053	1
del_19q13.33	17 (30%)	39	0.035564	1	0.0090349	1	0.00074838	0.369	0.01072	1	0.22677	1	0.45085	1	0.52587	1	0.45672	1
del_20p12.1	9 (16%)	47	1	1	0.67138	1	0.39082	1	0.28358	1	0.22037	1	0.40305	1	0.31743	1	0.29168	1
del_22q13.31	40 (71%)	16	0.56258	1	0.40029	1	0.89273	1	0.9508	1	0.54753	1	0.38841	1	0.47874	1	0.38445	1
del_xp21.1	18 (32%)	38	0.55618	1	0.38348	1	0.82	1	0.8138	1	0.36026	1	0.78376	1	0.73424	1	0.77896	1
del_xq25	23 (41%)	33	0.51537	1	0.29688	1	0.1117	1	0.30561	1	0.69171	1	1	1	0.53671	1	1	1