Clinical Features CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q FBXW7 22 (39%) 35 0.051073 1 0.71408 1 0.59502 1 0.49413 1 0.44144 1 1 1 0.93807 1 0.73706 1 KRAS 7 (12%) 50 0.31975 1 0.01865 1 0.032288 1 0.026396 1 0.4626 1 0.49386 1 0.51346 1 0.32242 1 TP53 51 (89%) 6 0.33095 1 0.59103 1 0.87748 1 0.82179 1 1 1 0.69897 1 1 1 1 1 PIK3CA 20 (35%) 37 0.26664 1 0.87519 1 0.36514 1 0.30281 1 0.10526 1 0.026837 1 0.162 1 0.027411 1 PPP2R1A 16 (28%) 41 1 1 0.70093 1 0.58445 1 0.85178 1 0.55965 1 0.63518 1 0.23427 1 1 1 PTEN 11 (19%) 46 0.012253 0.833 0.00021636 0.0156 0.0021245 0.151 0.0043349 0.303 0.096044 1 0.0087192 0.602 0.023688 1 0.024054 1 PIK3R1 6 (11%) 51 0.856 1 0.9503 1 0.54374 1 0.59158 1 0.42516 1 0.70487 1 0.74354 1 0.45918 1 ZBTB7B 6 (11%) 51 0.48285 1 0.9503 1 1 1 1 1 0.097756 1 0.19748 1 0.15025 1 0.2897 1 RB1 6 (11%) 51 0.54073 1 0.12102 1 0.079993 1 0.040097 1 0.83495 1 0.48353 1 0.9184 1 0.7124 1