		Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	64 (31%)	142	0.12695	1	0.01227	1	0.01761	1	0.11003	1	0.72814	1	0.04928	1	0.82898	1	0.00128	0.794
1q gain	97 (47%)	109	0.0147	1	0.02155	1	0.03073	1	0.28492	1	0.81239	1	0.35062	1	0.70253	1	0.01173	1
2p gain	45 (22%)	161	0.00194	1	0.01804	1	0.075119	1	0.060089	1	0.47133	1	0.10977	1	0.77403	1	0.15956	1
2q gain	29 (14%)	177	0.00021	0.133	0.19226	1	0.0070799	1	0.0050599	1	0.52866	1	0.1408	1	0.41039	1	0.54528	1
3p gain	55 (27%)	151	0.89561	1	0.3347	1	0.47603	1	0.59352	1	0.33054	1	0.76145	1	0.36954	1	0.31964	1
3q gain	126 (61%)	80	0.00186	1	0.00027	0.17	0.00023	0.145	0.00237	1	0.14749	1	0.0085299	1	0.0379	1	0.00016	0.101
4p gain	7 (3%)	199	1	1	0.81259	1	0.28977	1	0.65608	1	1	1	0.31381	1	0.70858	1	0.73034	1
4q gain	8 (4%)	198	0.29599	1	0.24044	1	0.59706	1	0.39463	1	0.31534	1	0.04263	1	0.2548	1	0.49806	1
5p gain	72 (35%)	134	0.00076999	0.481	0.34405	1	0.19176	1	0.5593	1	0.17673	1	0.03044	1	0.071109	1	0.64922	1
5q gain	33 (16%)	173	0.01004	1	0.87368	1	0.37512	1	0.87184	1	0.37467	1	0.83294	1	0.30346	1	0.72442	1
6p gain	40 (19%)	166	0.36349	1	0.03813	1	0.0246	1	0.061929	1	0.53049	1	0.097669	1	0.83778	1	0.02666	1
6q gain	25 (12%)	181	0.31066	1	0.29352	1	0.059259	1	0.080839	1	0.39236	1	0.078139	1	0.666	1	0.8138	1
7p gain	24 (12%)	182	0.02813	1	0.064839	1	0.02087	1	0.096939	1	0.0014	0.867	0.36394	1	0.0021	1	0.43763	1
7q gain	23 (11%)	183	0.04388	1	0.090789	1	0.086509	1	0.31623	1	0.01116	1	0.16545	1	0.01721	1	0.41782	1
8p gain	32 (16%)	174	0.82324	1	0.51683	1	0.12214	1	0.16112	1	1	1	0.55305	1	0.58205	1	0.03434	1
8q gain	56 (27%)	150	0.36303	1	0.29006	1	0.1127	1	0.054089	1	0.14916	1	0.03979	1	0.42206	1	0.04001	1
9p gain	32 (16%)	174	0.3512	1	0.21926	1	0.82837	1	0.15799	1	0.61311	1	0.8019	1	0.83622	1	0.55439	1
9q gain	31 (15%)	175	0.23789	1	0.0051899	1	0.072569	1	0.01284	1	0.0312	1	0.01894	1	0.096829	1	0.1636	1
10p gain	16 (8%)	190	0.29234	1	0.82166	1	0.43331	1	0.76784	1	0.71972	1	0.4777	1	0.61124	1	0.92443	1
10q gain	10 (5%)	196	0.70932	1	0.74377	1	1	1	0.51353	1	0.3256	1	0.67356	1	0.60972	1	0.96425	1
11p gain	7 (3%)	199	0.88861	1	0.78989	1	0.54807	1	0.04821	1	0.79614	1	0.56927	1	0.70881	1	0.14756	1
11q gain	7 (3%)	199	0.03063	1	0.58272	1	0.01837	1	0.00033	0.208	0.18115	1	0.21537	1	0.20025	1	0.02166	1
12p gain	35 (17%)	171	0.30612	1	0.47267	1	0.50976	1	0.3202	1	0.095069	1	0.40714	1	0.02217	1	0.8396	1
12q gain	32 (16%)	174	0.30248	1	0.14266	1	0.55168	1	0.066339	1	0.15563	1	0.53285	1	0.10249	1	0.71877	1
13q gain	16 (8%)	190	0.5573	1	0.33818	1	0.0268	1	0.04294	1	0.00337	1	0.050939	1	0.0054999	1	0.13985	1
14q gain	30 (15%)	176	0.25331	1	0.24183	1	0.51893	1	0.67169	1	0.1526	1	0.34764	1	0.083169	1	0.37734	1
15q gain	37 (18%)	169	0.74941	1	0.38516	1	0.94634	1	0.86354	1	0.24748	1	0.9682	1	0.63433	1	0.75616	1
16p gain	28 (14%)	178	0.03054	1	0.49445	1	0.69865	1	0.55121	1	0.068129	1	0.47624	1	0.093079	1	0.78486	1
16q gain	25 (12%)	181	0.17592	1	0.12837	1	0.4632	1	0.12782	1	0.0070699	1	0.081659	1	0.00339	1	0.28122	1
17p gain	15 (7%)	191	0.01428	1	0.00050999	0.32	0.83418	1	0.63993	1	0.58757	1	0.49143	1	0.49519	1	1	1
17q gain	32 (16%)	174	0.02072	1	0.02316	1	0.097879	1	0.25314	1	0.083369	1	0.27948	1	0.11803	1	0.61251	1
18p gain	27 (13%)	179	0.31231	1	0.15271	1	0.62609	1	0.28249	1	0.93192	1	0.27391	1	0.96494	1	0.13932	1
18q gain	16 (8%)	190	0.28959	1	0.32848	1	0.63318	1	0.34192	1	0.64655	1	0.33723	1	0.80378	1	0.39086	1
19p gain	33 (16%)	173	0.00215	1	0.11481	1	0.7381	1	0.78396	1	0.02309	1	0.060209	1	0.1157	1	0.64074	1
19q gain	47 (23%)	159	9.9999e-06	0.0064	0.11858	1	0.29957	1	0.04465	1	0.15862	1	0.2284	1	0.15149	1	0.57369	1
20p gain	71 (34%)	135	0.01742	1	0.01593	1	0.18152	1	0.01307	1	0.24431	1	0.03872	1	0.077129	1	0.46094	1
20q gain	77 (37%)	129	0.03883	1	0.054439	1	0.23729	1	0.17821	1	0.61608	1	0.03641	1	0.28317	1	0.4916	1
21q gain	28 (14%)	178	0.72351	1	0.70896	1	0.49442	1	0.77064	1	1	1	0.7801	1	0.50822	1	0.547	1
22q gain	25 (12%)	181	0.96018	1	0.23797	1	0.46178	1	0.68667	1	0.92736	1	0.16849	1	1	1	0.5667	1
xq gain	28 (14%)	178	0.23184	1	0.21132	1	0.35173	1	0.57699	1	0.04984	1	0.073299	1	0.099669	1	0.13307	1
1p loss	8 (4%)	198	0.00213	1	0.35082	1	0.04743	1	0.3712	1	0.90022	1	0.46797	1	0.665	1	0.72615	1
1q loss	7 (3%)	199	0.00058999	0.369	0.27059	1	0.02623	1	0.38067	1	0.2657	1	1	1	0.15915	1	0.73657	1
2p loss	12 (6%)	194	0.86294	1	0.57556	1	0.51565	1	0.83058	1	1	1	0.33852	1	0.86929	1	0.6746	1
2q loss	21 (10%)	185	0.63447	1	0.2651	1	0.067589	1	0.39885	1	0.64772	1	0.29261	1	1	1	0.27193	1
3p loss	50 (24%)	156	0.43152	1	0.01247	1	0.057189	1	0.00015	0.0952	0.03379	1	0.0078299	1	0.11771	1	0.00141	0.871
3q loss	8 (4%)	198	0.16952	1	0.03137	1	0.04833	1	0.02835	1	0.89847	1	0.78564	1	0.66563	1	0.40107	1
4p loss	86 (42%)	120	9.9999e-06	0.0064	0.20952	1	0.01371	1	0.00101	0.629	0.33804	1	0.0091499	1	0.51847	1	0.00307	1
4q loss	61 (30%)	145	9.9999e-06	0.0064	0.74796	1	0.19593	1	0.01419	1	0.53067	1	0.3313	1	0.94526	1	0.02964	1
5p loss	13 (6%)	193	0.15712	1	0.40987	1	1	1	0.72909	1	0.93859	1	0.62201	1	0.93704	1	0.03072	1
5q loss	37 (18%)	169	0.01587	1	0.71176	1	0.79724	1	0.85608	1	0.52413	1	0.24754	1	0.45619	1	0.00172	1
6p loss	30 (15%)	176	0.21221	1	0.65228	1	0.18363	1	0.40339	1	0.58052	1	0.28649	1	0.54465	1	0.60108	1
6q loss	51 (25%)	155	0.03618	1	0.33644	1	0.26745	1	0.45701	1	0.64992	1	0.22248	1	0.52642	1	0.7987	1
7p loss	19 (9%)	187	0.60502	1	0.44418	1	0.0365	1	0.03861	1	0.53998	1	0.19264	1	0.32328	1	0.053939	1
7q loss	29 (14%)	177	0.063859	1	0.10591	1	0.02058	1	0.10191	1	0.15784	1	0.20829	1	0.26516	1	0.0083899	1
8p loss	58 (28%)	148	0.0082399	1	0.24238	1	0.058829	1	0.93309	1	0.16813	1	0.20094	1	0.23603	1	0.1408	1
8q loss	18 (9%)	188	0.17895	1	0.099759	1	5e-05	0.0318	0.00172	1	0.04459	1	0.02154	1	0.02785	1	0.01998	1
9p loss	38 (18%)	168	0.01994	1	0.94217	1	0.084609	1	0.49468	1	0.94925	1	0.93849	1	0.97456	1	0.90312	1
9q loss	34 (17%)	172	0.0095399	1	0.19483	1	0.00296	1	0.04667	1	0.48263	1	0.18542	1	0.35554	1	0.26289	1
10p loss	45 (22%)	161	0.00094999	0.593	0.51468	1	0.53701	1	0.37175	1	0.31463	1	0.77596	1	0.24622	1	0.83281	1
10q loss	50 (24%)	156	0.0012	0.745	0.79905	1	0.72511	1	0.36981	1	0.31884	1	0.72743	1	0.26364	1	0.79556	1
11p loss	67 (33%)	139	0.073849	1	0.28536	1	0.21996	1	0.16985	1	0.20204	1	0.080279	1	0.12303	1	0.079349	1
11q loss	79 (38%)	127	0.00217	1	0.066499	1	0.45362	1	0.54884	1	0.78895	1	0.26258	1	0.8598	1	0.15829	1
12p loss	26 (13%)	180	0.00015	0.0952	0.13689	1	0.22391	1	0.33266	1	0.1913	1	0.9169	1	0.17421	1	0.096519	1
12q loss	9 (4%)	197	0.057949	1	0.4232	1	0.83408	1	0.58408	1	0.57841	1	0.6305	1	0.91253	1	0.76386	1
13q loss	58 (28%)	148	0.03237	1	0.11369	1	0.0113	1	0.04279	1	0.03023	1	0.00396	1	0.084629	1	0.087259	1
14q loss	21 (10%)	185	0.0098599	1	0.32723	1	0.03888	1	0.01248	1	0.23429	1	0.35901	1	0.052519	1	0.24874	1
15q loss	27 (13%)	179	0.10256	1	0.3444	1	0.28142	1	0.17126	1	0.5345	1	0.46805	1	0.8408	1	0.58438	1
16p loss	26 (13%)	180	0.22627	1	0.089679	1	0.17594	1	0.33022	1	0.17167	1	0.070509	1	0.13054	1	0.73024	1
16q loss	30 (15%)	176	0.66547	1	0.054099	1	0.066799	1	0.16384	1	0.12697	1	0.0085599	1	0.0287	1	0.060239	1
17p loss	61 (30%)	145	0.00263	1	0.17253	1	0.21525	1	0.052119	1	0.10429	1	0.087869	1	0.066549	1	0.21564	1
17q loss	19 (9%)	187	0.02532	1	0.55886	1	0.02433	1	0.04902	1	0.056149	1	0.59197	1	0.058589	1	0.45532	1
18p loss	39 (19%)	167	0.20876	1	0.083739	1	0.00157	0.969	0.14506	1	0.31534	1	0.03179	1	0.077709	1	0.01317	1
18q loss	53 (26%)	153	0.02768	1	0.00244	1	9.9999e-06	0.0064	0.00414	1	0.11245	1	0.00442	1	0.04139	1	0.00109	0.678
19p loss	37 (18%)	169	0.099689	1	0.099719	1	0.04233	1	0.23653	1	0.24815	1	0.34243	1	0.48508	1	0.095939	1
19q loss	19 (9%)	187	0.053219	1	0.11611	1	0.90807	1	0.47061	1	0.23336	1	0.34663	1	0.32153	1	0.80743	1
20p loss	14 (7%)	192	0.55167	1	0.58234	1	0.87333	1	0.55341	1	0.64517	1	0.46636	1	0.73763	1	0.20428	1
20q loss	7 (3%)	199	0.03995	1	0.11283	1	0.87366	1	0.29896	1	0.89396	1	1	1	1	1	0.92919	1
21q loss	32 (16%)	174	0.00302	1	0.15533	1	0.093709	1	0.00053999	0.339	0.69496	1	0.57225	1	0.30672	1	0.14271	1
22q loss	47 (23%)	159	0.052619	1	0.34788	1	0.18974	1	0.03761	1	0.62058	1	0.39676	1	0.57194	1	0.44404	1
xq loss	40 (19%)	166	0.17518	1	0.10279	1	0.26012	1	0.1342	1	0.069269	1	0.15659	1	0.02624	1	0.01411	1
