		Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		MIR_CNMF		MIR_CHIERARCHICAL		CN_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	166 (29%)	403	0.10585	1	0.32463	1	0.11919	1	0.68455	1	0.00258	1	0.092409	1	0.30775	1	0.6119	1	0.94944	1	0.21499	1	0.61778	1	0.15083	1	0.33916	1
1q gain	218 (38%)	351	0.77968	1	0.2704	1	0.69455	1	0.22904	1	9.9999e-06	0.0104	0.45349	1	0.50737	1	0.43537	1	0.27588	1	0.20388	1	0.098359	1	0.11563	1	0.17552	1
2p gain	178 (31%)	391	9.9999e-06	0.0104	9.9999e-06	0.0104	0.82113	1	0.00042	0.42	9.9999e-06	0.0104	0.03883	1	0.094249	1	0.00014	0.142	0.00158	1	0.82269	1	0.02682	1	0.7915	1	1	1
2q gain	150 (26%)	419	0.00044	0.44	5e-05	0.051	0.98425	1	0.00491	1	9.9999e-06	0.0104	0.098749	1	0.40709	1	0.00371	1	0.01866	1	0.611	1	0.0061399	1	0.10458	1	0.7258	1
3p gain	154 (27%)	415	0.33937	1	0.38882	1	0.04408	1	0.37374	1	0.01257	1	1	1	0.40562	1	0.78253	1	0.76607	1	0.91761	1	0.82097	1	0.90566	1	1	1
3q gain	268 (47%)	301	0.97482	1	0.80598	1	0.25654	1	0.42941	1	2e-05	0.0204	0.59413	1	0.25634	1	0.69637	1	0.92613	1	0.18142	1	0.087919	1	0.11838	1	0.20608	1
4p gain	57 (10%)	512	0.24609	1	0.19046	1	0.00486	1	0.059549	1	0.13386	1	0.45614	1	0.39672	1	0.60585	1	0.84088	1	0.31997	1	0.01862	1	0.5827	1	0.15758	1
4q gain	32 (6%)	537	0.67308	1	0.6964	1	0.15275	1	0.20699	1	0.03713	1	0.2697	1	0.45018	1	0.76391	1	0.85558	1	0.37416	1	0.04424	1	0.49519	1	0.16551	1
5p gain	196 (34%)	373	0.59316	1	0.67139	1	0.85445	1	0.7355	1	0.00012	0.122	0.48468	1	0.088319	1	0.1304	1	0.53745	1	0.23019	1	0.63416	1	0.63154	1	0.18124	1
5q gain	60 (11%)	509	0.083439	1	0.24412	1	0.80178	1	0.8322	1	0.50985	1	0.44133	1	0.38946	1	0.70891	1	0.41293	1	0.49578	1	0.81029	1	0.62927	1	0.31072	1
6p gain	166 (29%)	403	0.51144	1	0.00438	1	0.90135	1	0.0129	1	9.9999e-06	0.0104	0.86393	1	0.22767	1	0.15816	1	0.0078999	1	0.3613	1	0.065019	1	0.43593	1	0.86436	1
6q gain	96 (17%)	473	0.65481	1	0.052469	1	0.82179	1	0.02022	1	9.9999e-06	0.0104	0.78839	1	0.99712	1	0.0050499	1	0.02217	1	0.19376	1	0.02971	1	0.46853	1	0.6427	1
7p gain	181 (32%)	388	0.63093	1	0.53481	1	0.071999	1	0.10323	1	9.9999e-06	0.0104	0.50307	1	0.40157	1	0.56727	1	0.69815	1	0.92456	1	0.11501	1	0.36294	1	0.43505	1
7q gain	198 (35%)	371	0.65315	1	0.084749	1	0.29732	1	0.37884	1	2e-05	0.0204	0.46271	1	0.24725	1	0.9249	1	0.64328	1	0.15257	1	0.63281	1	0.053809	1	0.45067	1
8p gain	117 (21%)	452	0.070899	1	0.00363	1	0.29883	1	0.36229	1	0.71547	1	0.13641	1	0.0070499	1	0.6159	1	1	1	0.10206	1	0.49555	1	0.17688	1	0.066269	1
8q gain	238 (42%)	331	0.01996	1	0.00092999	0.917	0.061379	1	0.20044	1	0.17474	1	0.32041	1	0.38653	1	0.03078	1	0.086189	1	0.46421	1	0.86456	1	0.29349	1	0.37859	1
9p gain	91 (16%)	478	0.1126	1	0.42396	1	0.23753	1	0.86586	1	0.01902	1	0.39504	1	0.7267	1	0.69338	1	0.41195	1	0.1857	1	0.18646	1	0.49625	1	0.32926	1
9q gain	45 (8%)	524	0.25237	1	0.30304	1	0.090709	1	0.53386	1	0.17013	1	0.57662	1	0.0266	1	0.48573	1	0.089989	1	0.49876	1	0.75411	1	0.47376	1	0.50279	1
10p gain	184 (32%)	385	0.00397	1	0.021	1	0.67943	1	0.37638	1	9.9999e-06	0.0104	0.97938	1	0.01007	1	0.01113	1	0.12372	1	0.55997	1	0.00064999	0.646	0.51148	1	0.89237	1
10q gain	108 (19%)	461	0.00375	1	0.0091899	1	0.24211	1	0.11773	1	0.0012	1	0.76511	1	0.062209	1	0.10453	1	0.21996	1	0.72827	1	0.24439	1	0.96019	1	0.29394	1
11p gain	76 (13%)	493	0.71065	1	0.10036	1	0.63963	1	0.46763	1	0.34321	1	0.02824	1	0.02601	1	0.059159	1	0.03594	1	0.56098	1	0.83864	1	0.8923	1	0.36096	1
11q gain	114 (20%)	455	0.45563	1	0.33814	1	0.87621	1	0.12038	1	0.03937	1	0.16539	1	0.00037	0.371	0.30214	1	0.15783	1	0.51423	1	0.80777	1	0.8424	1	0.7617	1
12p gain	250 (44%)	319	7.9999e-05	0.0814	0.00075999	0.755	0.74236	1	4e-04	0.4	9.9999e-06	0.0104	0.30458	1	0.3191	1	0.00038	0.381	0.00188	1	0.18304	1	0.00023	0.232	0.30262	1	0.10957	1
12q gain	174 (31%)	395	0.0060099	1	0.056909	1	0.65071	1	0.04857	1	9.9999e-06	0.0104	0.02564	1	0.25454	1	0.00185	1	0.0084699	1	0.10215	1	0.01106	1	0.58105	1	0.10141	1
13q gain	60 (11%)	509	0.0059099	1	2e-04	0.202	0.57385	1	0.01662	1	0.00016	0.162	0.59333	1	0.31702	1	0.23123	1	0.43005	1	0.1918	1	0.072219	1	0.94119	1	0.68562	1
14q gain	58 (10%)	511	0.14094	1	0.19116	1	0.40594	1	0.69876	1	0.79927	1	0.33083	1	0.17279	1	0.50454	1	0.57034	1	0.65665	1	0.63167	1	0.56325	1	0.71795	1
15q gain	39 (7%)	530	0.8464	1	0.4806	1	0.085219	1	0.75547	1	0.41887	1	0.11394	1	0.10765	1	0.73479	1	0.93267	1	0.31562	1	0.20035	1	0.52596	1	0.10924	1
16p gain	58 (10%)	511	0.00273	1	0.00482	1	0.4022	1	0.17657	1	0.088989	1	0.34341	1	0.03457	1	0.65066	1	0.79884	1	0.12295	1	0.080829	1	0.19711	1	0.063599	1
16q gain	30 (5%)	539	0.00086999	0.86	0.04332	1	0.16202	1	0.22115	1	0.68834	1	0.45016	1	0.02663	1	1	1	0.36098	1	0.00096999	0.954	0.10458	1	0.00249	1	0.00060999	0.607
17p gain	22 (4%)	547	0.43282	1	0.11247	1	0.056119	1	0.052189	1	0.22451	1	0.50019	1	0.40782	1	0.21239	1	0.00336	1	0.17544	1	0.83728	1	0.41098	1	0.67029	1
17q gain	49 (9%)	520	0.32165	1	0.04412	1	0.8597	1	0.04866	1	0.7907	1	0.44815	1	0.27674	1	0.93675	1	0.02289	1	0.79084	1	0.84861	1	0.45458	1	0.9304	1
18p gain	117 (21%)	452	0.2282	1	0.13299	1	0.92844	1	0.40251	1	0.0051199	1	0.02224	1	0.1105	1	0.81212	1	0.68944	1	0.35215	1	0.23358	1	0.3483	1	0.30647	1
18q gain	71 (12%)	498	0.64828	1	0.23733	1	0.28525	1	0.35935	1	0.051789	1	0.51306	1	0.39833	1	0.48584	1	0.2709	1	0.10776	1	0.19613	1	0.054969	1	0.10207	1
19p gain	167 (29%)	402	0.068459	1	0.44119	1	0.56813	1	0.11561	1	5.9999e-05	0.0611	0.055509	1	0.20992	1	0.23493	1	0.47124	1	0.369	1	0.33374	1	0.54356	1	0.9811	1
19q gain	160 (28%)	409	0.20809	1	0.76776	1	0.8613	1	0.18401	1	9.9999e-06	0.0104	0.49436	1	0.37973	1	0.20563	1	0.43742	1	0.27215	1	0.67714	1	0.43432	1	0.99073	1
20p gain	282 (50%)	287	0.00144	1	0.00106	1	0.72546	1	0.00075999	0.755	9.9999e-06	0.0104	0.34134	1	0.33176	1	0.00267	1	0.12314	1	0.22353	1	0.00166	1	0.6022	1	0.81316	1
20q gain	320 (56%)	249	9.9999e-06	0.0104	0.00034	0.342	0.67227	1	9.9999e-05	0.101	9.9999e-06	0.0104	0.66156	1	0.078719	1	0.0088899	1	0.13582	1	0.25832	1	0.00496	1	0.67426	1	0.50886	1
21q gain	109 (19%)	460	0.29042	1	0.88052	1	0.96126	1	0.58214	1	0.00136	1	0.45587	1	0.39294	1	0.3372	1	0.84325	1	0.02374	1	0.04309	1	0.099119	1	0.76292	1
22q gain	25 (4%)	544	0.56467	1	0.58455	1	0.90115	1	0.63365	1	0.12638	1	0.36563	1	0.2624	1	0.46353	1	0.5288	1	0.054079	1	0.054849	1	0.091389	1	0.04197	1
xq gain	104 (18%)	465	0.55353	1	0.72827	1	0.83559	1	0.21148	1	0.00236	1	0.27623	1	0.79072	1	0.79664	1	0.82206	1	0.55155	1	0.36377	1	0.4762	1	0.54099	1
1p loss	61 (11%)	508	0.02969	1	0.00011	0.112	0.60547	1	0.23891	1	0.45128	1	0.03513	1	0.20323	1	0.63155	1	0.50921	1	0.44732	1	0.30567	1	0.04076	1	0.13777	1
1q loss	39 (7%)	530	0.095459	1	0.0081399	1	0.121	1	0.70368	1	0.97784	1	0.3524	1	0.52269	1	0.46599	1	1	1	0.97017	1	0.93403	1	0.23981	1	0.70992	1
2p loss	53 (9%)	516	0.93221	1	0.0417	1	0.82298	1	0.44121	1	0.51371	1	0.4824	1	0.89467	1	0.63996	1	0.81589	1	0.72136	1	0.40037	1	0.60138	1	0.77892	1
2q loss	59 (10%)	510	0.96784	1	0.26065	1	0.76105	1	0.14548	1	0.77923	1	0.79502	1	0.94548	1	0.67883	1	0.9277	1	0.67729	1	0.34981	1	0.66528	1	0.2448	1
3p loss	95 (17%)	474	0.04	1	0.00093999	0.926	0.88878	1	0.0060999	1	7.9999e-05	0.0814	0.63425	1	0.27766	1	0.062269	1	0.0064299	1	0.12403	1	0.092139	1	0.92087	1	0.74272	1
3q loss	41 (7%)	528	0.02058	1	0.04674	1	0.30355	1	0.054639	1	0.0059799	1	1	1	0.627	1	0.25214	1	0.076779	1	0.22325	1	0.00223	1	0.28799	1	0.22144	1
4p loss	312 (55%)	257	0.46405	1	0.02765	1	0.28172	1	0.5213	1	0.00436	1	0.14425	1	0.13105	1	0.6124	1	0.43626	1	0.066709	1	0.13041	1	0.054619	1	0.5593	1
4q loss	355 (62%)	214	0.28715	1	0.11418	1	0.45109	1	0.64625	1	0.00155	1	0.10091	1	0.01603	1	0.35588	1	0.35136	1	0.14017	1	0.11331	1	0.02725	1	0.26418	1
5p loss	129 (23%)	440	0.096339	1	0.028	1	0.48638	1	0.083269	1	0.02154	1	0.10751	1	0.077519	1	0.00017	0.172	0.04815	1	0.6652	1	0.087219	1	0.38287	1	0.38752	1
5q loss	218 (38%)	351	5e-04	0.499	0.0017	1	0.77475	1	0.01363	1	0.00082999	0.821	0.04578	1	0.11736	1	0.00089999	0.888	0.14502	1	0.54921	1	0.01057	1	0.30109	1	0.12814	1
6p loss	164 (29%)	405	0.96209	1	0.01888	1	0.36987	1	0.47045	1	0.059449	1	0.70072	1	0.89647	1	0.41208	1	0.04353	1	0.4796	1	0.10064	1	0.31839	1	0.94607	1
6q loss	239 (42%)	330	0.96272	1	0.077069	1	0.43503	1	0.098949	1	0.0178	1	0.62518	1	0.65286	1	0.01864	1	0.02098	1	0.79211	1	0.57165	1	0.92316	1	0.8797	1
7p loss	118 (21%)	451	0.98165	1	0.3556	1	0.43262	1	0.70989	1	0.30211	1	0.59916	1	0.27702	1	0.62078	1	0.58729	1	0.5362	1	0.80363	1	0.77878	1	0.58927	1
7q loss	81 (14%)	488	0.33319	1	0.086299	1	0.34806	1	0.30117	1	0.92031	1	0.8209	1	0.069709	1	0.47578	1	0.31091	1	0.12333	1	0.82132	1	0.5032	1	0.41574	1
8p loss	271 (48%)	298	0.74121	1	0.89213	1	0.24093	1	0.94575	1	0.00357	1	0.11844	1	0.30068	1	0.48261	1	0.70543	1	0.7006	1	0.03757	1	0.80957	1	0.4046	1
8q loss	88 (15%)	481	0.0080899	1	0.00479	1	0.52193	1	0.26289	1	0.00185	1	0.0215	1	0.23338	1	0.00093999	0.926	0.02799	1	0.6621	1	0.1241	1	0.75997	1	0.39801	1
9p loss	255 (45%)	314	0.00321	1	0.0063699	1	0.5116	1	0.18572	1	0.0081199	1	0.79055	1	0.54449	1	0.89783	1	0.10799	1	0.054109	1	0.25583	1	0.063829	1	0.03776	1
9q loss	280 (49%)	289	0.00488	1	0.01415	1	0.22611	1	0.02473	1	9.9999e-06	0.0104	0.59367	1	0.58527	1	0.00456	1	0.051499	1	0.18653	1	0.050159	1	0.25653	1	0.088679	1
10p loss	94 (17%)	475	0.29641	1	1	1	0.26189	1	0.36883	1	0.56227	1	0.60235	1	0.060449	1	0.81391	1	0.63754	1	0.45006	1	0.81228	1	0.42271	1	0.25156	1
10q loss	122 (21%)	447	0.973	1	0.86007	1	0.00395	1	0.32822	1	0.081489	1	0.36486	1	0.37117	1	0.66162	1	0.72449	1	0.76563	1	0.34677	1	0.86983	1	0.059209	1
11p loss	193 (34%)	376	0.23887	1	0.0115	1	0.5459	1	0.30929	1	0.12423	1	0.098249	1	0.61175	1	0.04054	1	0.11193	1	0.47341	1	0.14264	1	0.077199	1	0.096989	1
11q loss	144 (25%)	425	0.35646	1	0.79952	1	0.17917	1	0.53761	1	0.01554	1	0.46216	1	0.7096	1	0.27089	1	0.79777	1	0.51396	1	0.21499	1	0.10206	1	0.26991	1
12p loss	78 (14%)	491	0.003	1	0.01077	1	0.53888	1	0.01034	1	0.00297	1	0.78292	1	0.13264	1	0.31314	1	0.20499	1	0.0093799	1	0.0063699	1	0.00225	1	0.01715	1
12q loss	104 (18%)	465	0.068189	1	0.079279	1	0.75948	1	0.23294	1	0.058699	1	0.26842	1	0.55684	1	0.2437	1	0.19554	1	0.04307	1	0.0484	1	0.11081	1	0.080999	1
13q loss	303 (53%)	266	0.03456	1	0.0067499	1	0.79073	1	0.01302	1	0.0058399	1	0.01037	1	0.3947	1	0.46572	1	0.41825	1	0.25448	1	0.50446	1	0.095989	1	0.16777	1
14q loss	208 (37%)	361	0.21177	1	0.16458	1	0.96832	1	0.49161	1	9.9999e-06	0.0104	0.98045	1	0.61036	1	0.00393	1	0.04664	1	0.80111	1	0.3199	1	0.97468	1	0.77172	1
15q loss	276 (49%)	293	0.00050999	0.508	0.01338	1	8.9999e-05	0.0914	0.00036	0.361	9.9999e-06	0.0104	0.37473	1	0.8137	1	0.066319	1	0.61555	1	0.0066199	1	0.00081999	0.812	0.02992	1	0.00253	1
16p loss	325 (57%)	244	0.32054	1	0.82676	1	0.03754	1	0.31839	1	0.12392	1	0.80442	1	0.20118	1	0.052189	1	0.30933	1	0.079129	1	0.081399	1	0.1124	1	0.19936	1
16q loss	404 (71%)	165	0.56746	1	0.85677	1	0.00361	1	0.097369	1	0.00174	1	0.9479	1	0.24479	1	0.20422	1	0.42588	1	0.072559	1	0.15639	1	0.04789	1	0.17469	1
17p loss	471 (83%)	98	0.27655	1	0.21553	1	0.18038	1	0.1703	1	0.48239	1	0.54966	1	0.23971	1	0.10058	1	0.057969	1	0.47003	1	0.47642	1	0.13652	1	0.41911	1
17q loss	376 (66%)	193	0.060349	1	0.0211	1	0.02613	1	0.01027	1	0.96883	1	0.43406	1	0.33475	1	0.49152	1	0.094709	1	0.057979	1	0.6213	1	0.00013	0.132	0.12112	1
18p loss	234 (41%)	335	0.41633	1	0.89442	1	0.50929	1	0.02245	1	0.23529	1	0.31223	1	0.0062899	1	0.02309	1	0.11344	1	0.83711	1	0.54074	1	0.60993	1	0.77599	1
18q loss	290 (51%)	279	0.31575	1	0.87847	1	0.40653	1	0.97838	1	0.97121	1	0.81231	1	0.04784	1	0.01126	1	0.089849	1	0.97734	1	0.77882	1	0.82225	1	0.78655	1
19p loss	181 (32%)	388	0.98612	1	0.44049	1	0.23602	1	0.0228	1	0.01703	1	0.02079	1	0.85912	1	0.74459	1	0.25452	1	0.79997	1	0.10603	1	0.86093	1	0.6013	1
19q loss	172 (30%)	397	0.82313	1	0.38957	1	0.28439	1	0.0153	1	0.03865	1	0.090979	1	0.61723	1	1	1	0.4831	1	0.36273	1	0.090149	1	0.41819	1	0.79718	1
20p loss	49 (9%)	520	0.49813	1	0.83252	1	0.22057	1	0.68589	1	0.12785	1	0.10249	1	0.20044	1	0.01202	1	0.00054999	0.548	0.00079999	0.793	0.17347	1	0.0063099	1	0.48533	1
20q loss	31 (5%)	538	0.11485	1	0.49805	1	0.03821	1	0.50541	1	0.51213	1	0.04844	1	0.097039	1	0.13241	1	0.01365	1	0.136	1	0.37774	1	0.064829	1	0.20189	1
21q loss	195 (34%)	374	0.8196	1	0.053249	1	0.3856	1	0.17898	1	0.39748	1	0.65068	1	0.43815	1	0.58513	1	0.40849	1	0.68797	1	0.72904	1	0.14447	1	0.42202	1
22q loss	421 (74%)	148	0.0051699	1	0.092929	1	0.03594	1	0.1361	1	0.00034	0.342	0.070519	1	0.0095299	1	0.19105	1	0.12938	1	0.04248	1	0.60851	1	0.0496	1	0.02371	1
xq loss	273 (48%)	296	0.058849	1	0.16396	1	0.28908	1	0.86961	1	0.0058399	1	0.38743	1	0.04531	1	0.49467	1	0.89793	1	0.79868	1	0.40188	1	0.89606	1	0.15868	1
