		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	11 (3%)	408	5.9999e-05	0.0404	0.069439	1	0.0399	1	0.33803	1	0.075399	1	0.33155	1	0.14011	1	0.59575	1	0.18161	1	0.11493	1
1q gain	19 (5%)	400	9.9999e-06	0.00722	0.0054099	1	0.02164	1	0.17953	1	0.00306	1	0.071269	1	0.1016	1	0.66582	1	0.071169	1	0.091899	1
2p gain	8 (2%)	411	0.0074599	1	0.10891	1	NA	NA	NA	NA	0.03037	1	0.078269	1	0.2556	1	0.39806	1	0.00291	1	0.24919	1
2q gain	4 (1%)	415	0.0467	1	0.38352	1	NA	NA	NA	NA	0.64819	1	0.78652	1	0.32999	1	0.82619	1	0.02138	1	0.47533	1
3p gain	32 (8%)	387	9.9999e-06	0.00722	0.0084499	1	0.083489	1	0.46503	1	0.00375	1	0.02745	1	0.50972	1	0.13261	1	0.065839	1	0.063299	1
3q gain	45 (11%)	374	9.9999e-06	0.00722	0.03677	1	0.04213	1	0.17965	1	0.00014	0.0932	0.01295	1	0.38842	1	0.28247	1	0.10588	1	0.01283	1
4p gain	8 (2%)	411	0.0069299	1	0.32951	1	NA	NA	NA	NA	0.20645	1	0.89832	1	0.98316	1	1	1	1	1	0.2817	1
4q gain	7 (2%)	412	0.01909	1	0.31533	1	NA	NA	NA	NA	0.22431	1	0.58895	1	0.91874	1	1	1	0.79621	1	0.22033	1
5p gain	17 (4%)	402	9.9999e-06	0.00722	0.070019	1	0.29835	1	0.30764	1	0.01802	1	0.51356	1	0.79281	1	0.17588	1	0.0088999	1	0.00328	1
5q gain	12 (3%)	407	3e-05	0.0204	0.1231	1	NA	NA	NA	NA	0.061169	1	0.30548	1	0.81256	1	0.73546	1	0.35305	1	0.15962	1
6p gain	6 (1%)	413	0.01866	1	0.38147	1	NA	NA	NA	NA	0.063659	1	0.78315	1	0.51177	1	0.27803	1	0.33896	1	0.31854	1
6q gain	3 (1%)	416	0.02541	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	0.77944	1	0.29193	1	0.39204	1	0.77653	1
7p gain	82 (20%)	337	9.9999e-06	0.00722	9.9999e-06	0.00722	0.55697	1	0.72583	1	9.9999e-06	0.00722	0.0058799	1	0.04344	1	0.00125	0.802	0.00487	1	0.01154	1
7q gain	78 (19%)	341	9.9999e-06	0.00722	9.9999e-06	0.00722	0.62006	1	0.71343	1	9.9999e-06	0.00722	0.0080399	1	0.02698	1	0.00162	1	0.0066299	1	0.02769	1
8p gain	54 (13%)	365	9.9999e-06	0.00722	9.9999e-06	0.00722	0.0059299	1	0.0083199	1	9.9999e-06	0.00722	0.00291	1	0.13895	1	0.03506	1	0.00134	0.854	0.13892	1
8q gain	96 (23%)	323	9.9999e-06	0.00722	8.9999e-05	0.0601	0.00216	1	0.0052699	1	9.9999e-06	0.00722	0.00016	0.106	0.00032	0.211	0.00128	0.818	2e-05	0.0137	0.00107	0.691
9p gain	23 (5%)	396	9.9999e-06	0.00722	0.34844	1	0.48358	1	0.17596	1	0.4707	1	0.38147	1	0.25074	1	0.46261	1	0.71325	1	0.2509	1
9q gain	37 (9%)	382	9.9999e-06	0.00722	0.083659	1	0.02608	1	0.01325	1	0.14522	1	0.0322	1	0.12347	1	0.01532	1	0.36643	1	0.096719	1
10p gain	10 (2%)	409	0.01069	1	0.31715	1	0.78501	1	0.77857	1	0.49741	1	0.18268	1	0.067969	1	0.093479	1	0.12278	1	0.28294	1
10q gain	12 (3%)	407	0.00185	1	0.36115	1	0.04014	1	0.03994	1	0.48503	1	0.13416	1	0.30902	1	0.083029	1	0.33315	1	0.24473	1
11p gain	17 (4%)	402	9.9999e-06	0.00722	0.20888	1	0.76843	1	0.66413	1	0.01356	1	0.39865	1	0.83035	1	0.45715	1	0.47449	1	0.12073	1
11q gain	20 (5%)	399	9.9999e-06	0.00722	0.1643	1	0.76771	1	0.66603	1	0.0073899	1	0.24064	1	0.50326	1	0.48913	1	0.40762	1	0.11799	1
12p gain	11 (3%)	408	0.00393	1	0.038	1	NA	NA	NA	NA	0.33171	1	0.24431	1	0.099919	1	0.27243	1	0.082879	1	0.60712	1
12q gain	12 (3%)	407	0.01781	1	0.03652	1	0.46882	1	0.62981	1	0.087739	1	0.49145	1	0.080159	1	0.44887	1	0.21179	1	0.90303	1
13q gain	5 (1%)	414	0.058739	1	0.1144	1	NA	NA	NA	NA	0.39288	1	0.14116	1	0.57725	1	0.12146	1	0.13818	1	0.376	1
14q gain	7 (2%)	412	0.00073999	0.482	0.080439	1	0.78611	1	0.78309	1	0.16995	1	0.24501	1	0.26817	1	0.29273	1	0.56699	1	0.26211	1
15q gain	5 (1%)	414	0.13104	1	1	1	NA	NA	NA	NA	1	1	0.83869	1	0.76092	1	0.71746	1	1	1	0.44754	1
16p gain	23 (5%)	396	5e-05	0.0338	0.33291	1	0.81766	1	0.65941	1	0.27187	1	0.066449	1	0.17335	1	0.0054299	1	0.01007	1	0.071289	1
16q gain	7 (2%)	412	0.26666	1	0.86186	1	0.67659	1	0.55847	1	0.87598	1	0.77342	1	0.33309	1	0.1833	1	0.34779	1	0.9757	1
17p gain	5 (1%)	414	0.060039	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA	0.65323	1	0.4838	1	0.10984	1	0.15783	1
17q gain	8 (2%)	411	0.00192	1	0.82802	1	0.47238	1	0.78026	1	0.38079	1	1	1	0.89229	1	0.35917	1	0.20468	1	0.2662	1
18p gain	13 (3%)	406	0.00084999	0.553	1	1	0.89863	1	0.66302	1	0.20862	1	0.93465	1	0.84098	1	0.92989	1	0.77441	1	0.45865	1
18q gain	7 (2%)	412	0.050049	1	1	1	1	1	0.49122	1	0.22356	1	0.77763	1	0.53143	1	0.76848	1	0.56705	1	0.21845	1
19p gain	8 (2%)	411	5e-05	0.0338	0.31437	1	NA	NA	NA	NA	0.28939	1	0.34788	1	0.16065	1	0.072519	1	0.39916	1	0.056279	1
19q gain	9 (2%)	410	2e-05	0.0137	0.32982	1	0.78105	1	0.78038	1	0.18505	1	0.20988	1	0.12806	1	0.051879	1	0.23174	1	0.02164	1
20p gain	17 (4%)	402	2e-05	0.0137	0.02189	1	0.37141	1	0.18651	1	0.01881	1	0.03468	1	0.074999	1	0.33242	1	0.00033	0.217	0.01522	1
20q gain	18 (4%)	401	9.9999e-06	0.00722	0.070529	1	0.61902	1	0.88761	1	0.21222	1	0.16514	1	0.3125	1	0.28378	1	0.0218	1	0.073259	1
21q gain	16 (4%)	403	9.9999e-06	0.00722	0.069359	1	0.4423	1	0.4488	1	0.0324	1	0.10778	1	0.059289	1	0.01608	1	0.01912	1	0.01592	1
xq gain	4 (1%)	415	0.01071	1	0.38232	1	NA	NA	NA	NA	0.64673	1	0.6331	1	0.17733	1	0.82743	1	0.02152	1	0.51809	1
1p loss	16 (4%)	403	9.9999e-06	0.00722	0.070009	1	0.25525	1	0.22838	1	0.03953	1	0.052499	1	0.058579	1	0.01785	1	0.03018	1	0.052109	1
1q loss	4 (1%)	415	0.093269	1	NA	NA	NA	NA	NA	NA	0.6477	1	0.63097	1	0.083699	1	0.12427	1	0.071149	1	0.077669	1
2p loss	9 (2%)	410	0.00268	1	0.22021	1	NA	NA	NA	NA	0.20459	1	0.01333	1	0.42195	1	0.73234	1	0.29708	1	0.27065	1
2q loss	12 (3%)	407	0.00025	0.165	0.35545	1	NA	NA	NA	NA	0.36818	1	0.067279	1	0.23101	1	0.73789	1	0.81318	1	0.082549	1
3p loss	7 (2%)	412	0.43649	1	0.15829	1	NA	NA	NA	NA	0.13581	1	0.16023	1	0.072019	1	0.47113	1	0.02081	1	0.18639	1
3q loss	4 (1%)	415	0.63105	1	0.63378	1	NA	NA	NA	NA	0.77779	1	0.6303	1	0.03176	1	0.076809	1	0.39146	1	0.02983	1
4p loss	15 (4%)	404	5.9999e-05	0.0404	0.25806	1	0.29713	1	0.30726	1	0.03433	1	0.074289	1	0.0057699	1	0.082349	1	0.0088499	1	0.01534	1
4q loss	10 (2%)	409	0.00016	0.106	0.58491	1	0.78497	1	0.78124	1	0.10218	1	0.15609	1	0.37206	1	0.25782	1	0.28347	1	0.23802	1
5p loss	6 (1%)	413	0.00104	0.674	0.23153	1	0.78268	1	1	1	0.33147	1	0.053289	1	0.69357	1	0.48562	1	0.74371	1	0.15494	1
5q loss	14 (3%)	405	9.9999e-06	0.00722	0.36056	1	0.25411	1	0.22807	1	0.21347	1	0.31952	1	0.12976	1	0.00388	1	0.0074499	1	0.01683	1
6p loss	21 (5%)	398	9.9999e-06	0.00722	0.00444	1	0.25355	1	0.22738	1	0.0062699	1	0.01171	1	0.5349	1	0.01939	1	0.16381	1	0.02344	1
6q loss	32 (8%)	387	9.9999e-06	0.00722	0.00072999	0.477	0.076779	1	0.16294	1	0.0051199	1	0.0051999	1	0.35481	1	0.01111	1	0.062749	1	0.077059	1
8p loss	140 (33%)	279	0.00239	1	9.9999e-06	0.00722	0.54687	1	0.93379	1	9.9999e-06	0.00722	2e-05	0.0137	2e-05	0.0137	0.01138	1	0.0055599	1	0.03133	1
8q loss	20 (5%)	399	0.46183	1	0.0385	1	1	1	1	1	0.00283	1	0.067729	1	0.45155	1	0.13838	1	0.15755	1	0.084519	1
9p loss	18 (4%)	401	0.00025	0.165	0.61973	1	0.085369	1	0.072649	1	0.058769	1	0.02822	1	0.4957	1	0.5419	1	0.04066	1	0.31188	1
9q loss	7 (2%)	412	0.052259	1	0.45259	1	0.44339	1	0.44954	1	0.53325	1	1	1	0.55387	1	0.76806	1	0.3483	1	0.52938	1
10p loss	31 (7%)	388	9.9999e-06	0.00722	0.00024	0.159	0.0066599	1	0.01276	1	9.9999e-05	0.0667	0.00133	0.849	0.00449	1	0.00101	0.655	0.35474	1	0.00302	1
10q loss	34 (8%)	385	9.9999e-06	0.00722	0.01627	1	0.04003	1	0.03924	1	0.0187	1	0.01956	1	0.004	1	0.00022	0.146	0.17464	1	0.091239	1
11p loss	6 (1%)	413	0.01922	1	1	1	NA	NA	NA	NA	0.33009	1	0.29501	1	0.51043	1	0.65647	1	0.33882	1	0.84297	1
11q loss	3 (1%)	416	0.25956	1	NA	NA	NA	NA	NA	NA	0.40587	1	0.78534	1	0.77891	1	0.76048	1	1	1	1	1
12p loss	40 (10%)	379	9.9999e-06	0.00722	0.12696	1	0.19188	1	0.43567	1	0.20812	1	0.13456	1	0.01926	1	0.0078999	1	0.080989	1	0.02608	1
12q loss	17 (4%)	402	6.9999e-05	0.047	0.61806	1	0.17456	1	0.12229	1	0.30433	1	0.42451	1	0.17454	1	0.1637	1	0.26598	1	0.20844	1
13q loss	62 (15%)	357	9.9999e-06	0.00722	0.3098	1	0.55357	1	0.45707	1	0.2632	1	0.30044	1	0.41389	1	0.15504	1	0.14529	1	0.00358	1
14q loss	19 (5%)	400	0.00014	0.0932	0.10022	1	0.4658	1	0.4873	1	0.085569	1	0.19586	1	0.0084099	1	0.12703	1	0.068099	1	0.02635	1
15q loss	24 (6%)	395	9.9999e-06	0.00722	0.01817	1	0.03938	1	0.093729	1	0.01208	1	0.083119	1	0.02255	1	0.0075099	1	0.00105	0.679	0.57222	1
16p loss	29 (7%)	390	0.00059999	0.393	0.082849	1	0.45048	1	0.35052	1	0.12484	1	0.65301	1	0.01184	1	0.61967	1	0.04166	1	0.29093	1
16q loss	87 (21%)	332	9.9999e-06	0.00722	0.00113	0.728	0.50523	1	0.19743	1	0.051509	1	0.03451	1	0.03245	1	0.00094999	0.617	0.0036	1	0.16402	1
17p loss	60 (14%)	359	9.9999e-06	0.00722	0.0092499	1	0.00353	1	0.0093299	1	7.9999e-05	0.0536	6.9999e-05	0.047	0.17933	1	0.077049	1	0.074399	1	0.26741	1
17q loss	14 (3%)	405	3e-05	0.0204	0.02792	1	0.45004	1	0.38715	1	0.0097999	1	0.01217	1	0.053409	1	0.00274	1	0.0456	1	0.01014	1
18p loss	55 (13%)	364	9.9999e-06	0.00722	0.0072499	1	0.062789	1	0.067279	1	0.02216	1	0.14189	1	0.26532	1	0.02072	1	0.057089	1	0.27261	1
18q loss	82 (20%)	337	9.9999e-06	0.00722	0.02778	1	0.01558	1	0.01926	1	0.0087999	1	0.02068	1	0.2646	1	7.9999e-05	0.0536	0.04772	1	0.12933	1
19p loss	13 (3%)	406	0.00126	0.806	0.60591	1	0.62483	1	0.48717	1	0.34653	1	0.9273	1	0.12148	1	0.18287	1	0.04508	1	0.12003	1
19q loss	13 (3%)	406	0.00124	0.797	0.60675	1	0.62184	1	0.49128	1	0.34821	1	0.927	1	0.12086	1	0.18349	1	0.04535	1	0.12056	1
20p loss	15 (4%)	404	0.26212	1	0.10997	1	0.89561	1	1	1	0.26966	1	0.48916	1	0.15575	1	0.28895	1	0.57111	1	0.11837	1
20q loss	8 (2%)	411	0.076999	1	0.082239	1	1	1	1	1	0.16646	1	0.24502	1	0.01993	1	0.0282	1	0.36442	1	0.0193	1
21q loss	16 (4%)	403	0.0011	0.709	0.3505	1	0.50564	1	0.50785	1	0.19137	1	0.1087	1	0.57555	1	0.083669	1	0.16645	1	0.77727	1
22q loss	37 (9%)	382	9.9999e-06	0.00722	0.056259	1	0.44018	1	0.80536	1	0.10648	1	0.064649	1	0.061439	1	0.01198	1	0.39427	1	3e-05	0.0204
xq loss	27 (6%)	392	9.9999e-06	0.00722	0.00125	0.802	0.11105	1	0.19566	1	0.00070999	0.464	0.00058999	0.387	0.0465	1	0.00191	1	0.00176	1	0.00255	1
