		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	44 (12%)	325	9.9999e-06	0.0079	0.052199	1	0.0053399	1	0.60869	1	0.01744	1	0.40237	1	0.0102	1	0.085279	1	0.00048	0.289	0.04723	1
1q gain	88 (24%)	281	9.9999e-06	0.0079	0.00023	0.145	0.0398	1	0.1768	1	5e-05	0.0333	0.0075499	1	0.01469	1	0.0097599	1	0.00084999	0.502	0.01657	1
2p gain	61 (17%)	308	9.9999e-06	0.0079	0.0062399	1	0.02158	1	0.11802	1	0.14288	1	0.02795	1	0.00095999	0.559	0.0374	1	0.00273	1	0.00122	0.699
2q gain	52 (14%)	317	9.9999e-06	0.0079	0.16324	1	0.23896	1	0.55694	1	0.0448	1	0.02993	1	0.1175	1	0.28286	1	0.10139	1	0.058359	1
3p gain	40 (11%)	329	0.0052899	1	0.01184	1	0.79112	1	0.0255	1	0.62657	1	0.22301	1	0.61216	1	0.58049	1	0.10219	1	0.34353	1
3q gain	69 (19%)	300	0.01343	1	0.31699	1	0.87431	1	0.14938	1	0.16802	1	0.02922	1	0.59678	1	0.52515	1	0.16453	1	0.63794	1
4p gain	13 (4%)	356	0.15923	1	0.50475	1	1	1	0.44832	1	0.38782	1	0.4271	1	0.13459	1	0.93554	1	0.72613	1	0.54097	1
4q gain	9 (2%)	360	0.75864	1	0.28932	1	0.86713	1	0.18601	1	0.091589	1	0.53925	1	0.48563	1	0.45549	1	0.27009	1	0.25971	1
5p gain	84 (23%)	285	9.9999e-06	0.0079	9.9999e-06	0.0079	0.26271	1	0.95982	1	9.9999e-06	0.0079	0.00469	1	0.00193	1	6.9999e-05	0.0463	0.00156	0.872	9.9999e-06	0.0079
5q gain	34 (9%)	335	0.00084999	0.502	0.095159	1	0.65839	1	0.10585	1	0.10513	1	0.3503	1	0.68998	1	0.47439	1	0.49459	1	0.47069	1
6p gain	69 (19%)	300	9.9999e-06	0.0079	9.9999e-06	0.0079	0.082899	1	0.29847	1	0.00024	0.15	0.00405	1	6.9999e-05	0.0463	0.00053999	0.325	0.00013	0.0841	9.9999e-06	0.0079
6q gain	55 (15%)	314	9.9999e-06	0.0079	9.9999e-06	0.0079	0.11944	1	0.24734	1	0.00027	0.168	0.0080999	1	0.00015	0.0966	0.03347	1	0.00011	0.0717	0.00098999	0.574
7p gain	161 (44%)	208	9.9999e-06	0.0079	0.00211	1	0.61185	1	0.83321	1	0.397	1	0.00078999	0.468	0.03135	1	0.11369	1	0.01538	1	0.00142	0.799
7q gain	139 (38%)	230	9.9999e-06	0.0079	0.03838	1	0.84231	1	0.60784	1	0.50815	1	0.0077199	1	0.11946	1	0.32791	1	0.28598	1	0.04593	1
8p gain	155 (42%)	214	2e-05	0.0138	0.01151	1	0.56475	1	0.39193	1	0.34993	1	0.11481	1	0.28314	1	0.64634	1	0.0080799	1	0.21002	1
8q gain	208 (56%)	161	0.00134	0.76	0.01663	1	0.78795	1	0.29893	1	0.02561	1	0.01991	1	0.0052299	1	0.02753	1	0.00023	0.145	0.00341	1
9p gain	48 (13%)	321	0.096979	1	1	1	0.56773	1	0.92363	1	0.37325	1	0.58218	1	0.24271	1	0.82693	1	0.069079	1	0.52666	1
9q gain	61 (17%)	308	0.23817	1	0.98164	1	0.24594	1	0.99444	1	0.43	1	0.92739	1	0.42972	1	0.52549	1	0.50278	1	0.60589	1
10p gain	85 (23%)	284	9.9999e-06	0.0079	2e-05	0.0138	0.10899	1	0.42952	1	0.00164	0.909	0.14758	1	0.19865	1	0.00047	0.284	0.067959	1	0.00028	0.174
10q gain	59 (16%)	310	9.9999e-06	0.0079	0.0064799	1	0.12889	1	0.74279	1	0.02007	1	0.11227	1	0.15061	1	0.14696	1	0.23597	1	0.04012	1
11p gain	45 (12%)	324	0.00121	0.696	0.04082	1	0.93379	1	0.84451	1	0.28257	1	0.39354	1	0.0058499	1	0.0052699	1	0.01791	1	0.04747	1
11q gain	53 (14%)	316	9.9999e-06	0.0079	0.00157	0.874	0.83719	1	1	1	0.31198	1	0.0062199	1	0.00066999	0.401	0.00092999	0.543	0.0063499	1	0.00125	0.715
12p gain	77 (21%)	292	0.00289	1	0.24228	1	0.2382	1	0.33724	1	0.16758	1	0.102	1	0.00139	0.784	0.32295	1	0.0070199	1	0.11549	1
12q gain	66 (18%)	303	0.055769	1	0.96609	1	0.43884	1	0.42248	1	0.96596	1	0.27661	1	0.096369	1	0.54441	1	0.27298	1	0.43044	1
13q gain	129 (35%)	240	9.9999e-06	0.0079	0.00019	0.12	0.56973	1	0.63654	1	0.02234	1	5.9999e-05	0.04	0.0095399	1	0.00343	1	0.00018	0.115	6.9999e-05	0.0463
14q gain	23 (6%)	346	0.00035	0.214	0.25082	1	0.7979	1	0.646	1	0.64115	1	0.52472	1	0.0089299	1	0.63679	1	0.0363	1	0.8202	1
15q gain	31 (8%)	338	5.9999e-05	0.04	0.00211	1	0.20793	1	0.82682	1	0.02005	1	0.12549	1	0.28211	1	0.26762	1	0.36486	1	0.22734	1
16p gain	52 (14%)	317	0.00072999	0.434	0.0095999	1	0.39253	1	0.11344	1	0.073279	1	0.28609	1	0.7541	1	0.83355	1	0.82765	1	0.73245	1
16q gain	42 (11%)	327	0.0067099	1	0.20217	1	0.67268	1	0.2624	1	0.18849	1	0.62419	1	0.56956	1	0.93	1	0.32046	1	0.85397	1
17p gain	21 (6%)	348	0.03731	1	0.86082	1	0.84313	1	0.7737	1	0.50561	1	0.27768	1	0.47236	1	0.51294	1	0.34295	1	0.58886	1
17q gain	46 (12%)	323	0.00091999	0.541	0.21151	1	0.94072	1	0.90203	1	0.53085	1	0.20136	1	0.28874	1	0.66168	1	0.2211	1	0.462	1
18p gain	66 (18%)	303	9.9999e-06	0.0079	9.9999e-06	0.0079	0.095349	1	0.0455	1	0.01556	1	0.00272	1	0.00026	0.162	0.00023	0.145	0.00074999	0.445	0.00076999	0.457
18q gain	45 (12%)	324	0.00369	1	0.0062099	1	0.5966	1	0.23734	1	0.37142	1	0.03298	1	0.04769	1	0.059619	1	0.1315	1	0.092229	1
19p gain	46 (12%)	323	0.01948	1	0.92924	1	0.65734	1	0.087609	1	0.60834	1	0.90791	1	0.76608	1	1	1	0.74055	1	0.45844	1
19q gain	61 (17%)	308	0.00131	0.745	0.36115	1	0.29743	1	0.095629	1	0.01864	1	0.345	1	0.18411	1	0.03243	1	0.10599	1	0.067699	1
20p gain	201 (54%)	168	9.9999e-06	0.0079	0.00012	0.0778	0.084929	1	0.14874	1	0.00069999	0.418	9.9999e-06	0.0079	0.0061399	1	0.00053999	0.325	0.02792	1	0.00011	0.0717
20q gain	231 (63%)	138	9.9999e-06	0.0079	9.9999e-06	0.0079	0.052539	1	0.22739	1	9.9999e-06	0.0079	9.9999e-06	0.0079	0.00019	0.12	9.9999e-06	0.0079	0.01472	1	9.9999e-06	0.0079
21q gain	21 (6%)	348	3e-05	0.0204	0.00031	0.192	0.14493	1	0.63847	1	0.0097699	1	0.03152	1	0.01962	1	0.00041	0.249	0.01952	1	0.00071999	0.429
22q gain	28 (8%)	341	0.00062999	0.377	0.13612	1	0.84604	1	0.21796	1	0.25549	1	0.067049	1	0.24257	1	0.57763	1	0.23588	1	0.4146	1
xq gain	44 (12%)	325	9.9999e-06	0.0079	0.00017	0.109	0.74829	1	0.50719	1	0.052449	1	0.00042	0.255	0.056919	1	0.43894	1	0.12522	1	0.04689	1
1p loss	46 (12%)	323	9.9999e-06	0.0079	0.00011	0.0717	0.059279	1	0.29535	1	0.03627	1	0.01123	1	0.33739	1	0.02431	1	0.12877	1	0.0057099	1
1q loss	21 (6%)	348	5.9999e-05	0.04	0.00014	0.0903	0.03346	1	0.30067	1	0.56528	1	0.2158	1	0.23022	1	0.31555	1	0.24326	1	0.11846	1
2p loss	20 (5%)	349	0.00017	0.109	0.00091999	0.541	0.35026	1	0.53512	1	0.01548	1	0.49052	1	0.12573	1	0.16401	1	0.066689	1	0.59086	1
2q loss	24 (7%)	345	4e-05	0.0268	7.9999e-05	0.0526	0.72927	1	0.93334	1	0.01134	1	0.41207	1	0.1232	1	0.01517	1	0.02297	1	0.15574	1
3p loss	74 (20%)	295	9.9999e-06	0.0079	0.01739	1	0.35978	1	0.19943	1	0.00324	1	3e-04	0.186	0.0095799	1	0.0050299	1	0.01061	1	0.0053299	1
3q loss	47 (13%)	322	9.9999e-06	0.0079	0.00244	1	0.20763	1	0.27197	1	9.9999e-05	0.0654	2e-05	0.0138	0.00261	1	0.00195	1	0.00032	0.197	0.00176	0.968
4p loss	139 (38%)	230	9.9999e-06	0.0079	2e-05	0.0138	0.2803	1	0.10218	1	0.00057999	0.348	0.00021	0.133	0.00426	1	9.9999e-06	0.0079	0.00161	0.895	9.9999e-06	0.0079
4q loss	137 (37%)	232	9.9999e-06	0.0079	3e-05	0.0204	0.070739	1	0.0222	1	0.0062199	1	0.00107	0.618	0.0078899	1	9.9999e-06	0.0079	0.00314	1	9.9999e-06	0.0079
5p loss	47 (13%)	322	9.9999e-06	0.0079	0.00297	1	0.21814	1	0.75641	1	0.00452	1	0.01344	1	0.00474	1	0.0050599	1	0.00091999	0.541	0.00017	0.109
5q loss	81 (22%)	288	9.9999e-06	0.0079	9.9999e-06	0.0079	0.62049	1	0.97688	1	9.9999e-06	0.0079	3e-05	0.0204	2e-05	0.0138	9.9999e-06	0.0079	2e-05	0.0138	9.9999e-06	0.0079
6p loss	43 (12%)	326	9.9999e-06	0.0079	0.00313	1	0.14989	1	0.91253	1	0.02362	1	0.0123	1	0.10863	1	0.00192	1	0.065109	1	0.00232	1
6q loss	56 (15%)	313	9.9999e-06	0.0079	0.00191	1	0.76533	1	0.68091	1	0.04171	1	0.12619	1	0.6028	1	0.02696	1	0.32626	1	0.071709	1
7p loss	14 (4%)	355	0.00133	0.755	0.0073999	1	0.44269	1	0.4027	1	0.00162	0.899	0.21934	1	0.18802	1	0.01774	1	3e-04	0.186	0.00244	1
7q loss	26 (7%)	343	2e-05	0.0138	0.00265	1	0.65255	1	0.3741	1	0.02758	1	0.18912	1	0.04623	1	0.066019	1	0.00018	0.115	0.04382	1
8p loss	65 (18%)	304	9.9999e-06	0.0079	0.04416	1	0.39925	1	0.76845	1	0.0086199	1	0.00138	0.781	0.0051199	1	0.0076599	1	3e-05	0.0204	0.00094999	0.554
8q loss	20 (5%)	349	0.01976	1	0.4226	1	0.94171	1	0.23952	1	0.69969	1	0.95945	1	0.36716	1	0.63096	1	0.40846	1	0.75322	1
9p loss	116 (31%)	253	9.9999e-06	0.0079	9.9999e-06	0.0079	0.00165	0.912	0.00028	0.174	9.9999e-06	0.0079	0.00013	0.0841	0.00090999	0.536	3e-05	0.0204	0.068009	1	9.9999e-05	0.0654
9q loss	81 (22%)	288	9.9999e-06	0.0079	0.00145	0.813	0.24701	1	0.01648	1	0.00015	0.0966	0.01668	1	0.00148	0.829	0.00097999	0.569	0.0057999	1	0.00156	0.872
10p loss	49 (13%)	320	3e-05	0.0204	0.03612	1	0.55222	1	0.089259	1	0.015	1	0.073549	1	0.01202	1	0.01159	1	0.0061999	1	0.01454	1
10q loss	55 (15%)	314	9.9999e-06	0.0079	0.0045	1	0.60915	1	0.03181	1	0.00091999	0.541	0.00256	1	0.0086799	1	0.01911	1	0.01288	1	0.00112	0.645
11p loss	54 (15%)	315	2e-05	0.0138	0.01151	1	0.0091099	1	0.13564	1	0.098699	1	0.19767	1	0.12053	1	0.01922	1	0.13168	1	0.0069299	1
11q loss	52 (14%)	317	0.00121	0.696	0.24105	1	0.52851	1	0.38358	1	0.67872	1	0.60596	1	0.30615	1	0.28824	1	0.10277	1	0.14372	1
12p loss	48 (13%)	321	9.9999e-06	0.0079	9.9999e-06	0.0079	0.26367	1	0.097549	1	8.9999e-05	0.0591	9.9999e-06	0.0079	0.061819	1	9.9999e-06	0.0079	0.02437	1	9.9999e-06	0.0079
12q loss	38 (10%)	331	9.9999e-06	0.0079	2e-05	0.0138	0.54453	1	0.1138	1	0.00338	1	0.0058099	1	0.66455	1	0.00492	1	0.17839	1	0.00021	0.133
13q loss	31 (8%)	338	5.9999e-05	0.04	0.69399	1	0.68584	1	0.3041	1	0.28017	1	0.60121	1	0.72842	1	0.91102	1	0.33471	1	0.60335	1
14q loss	88 (24%)	281	9.9999e-06	0.0079	8.9999e-05	0.0591	0.56094	1	0.53055	1	0.00111	0.64	0.0069099	1	0.03648	1	0.00143	0.804	0.0134	1	0.00467	1
15q loss	78 (21%)	291	9.9999e-06	0.0079	0.00138	0.781	0.01033	1	0.64759	1	0.00015	0.0966	0.00165	0.912	0.00394	1	0.00031	0.192	0.00031	0.192	0.00011	0.0717
16p loss	77 (21%)	292	9.9999e-06	0.0079	0.00036	0.22	0.81087	1	0.84218	1	9.9999e-06	0.0079	9.9999e-06	0.0079	2e-05	0.0138	8.9999e-05	0.0591	2e-05	0.0138	9.9999e-06	0.0079
16q loss	86 (23%)	283	9.9999e-06	0.0079	9.9999e-06	0.0079	0.04678	1	0.083229	1	9.9999e-06	0.0079	2e-05	0.0138	0.00028	0.174	0.00024	0.15	0.00445	1	3e-05	0.0204
17p loss	131 (36%)	238	9.9999e-06	0.0079	9.9999e-06	0.0079	0.50377	1	0.02861	1	9.9999e-06	0.0079	9.9999e-06	0.0079	0.00018	0.115	4e-05	0.0268	6.9999e-05	0.0463	9.9999e-06	0.0079
17q loss	61 (17%)	308	9.9999e-06	0.0079	9.9999e-06	0.0079	0.3985	1	0.0097699	1	0.00105	0.608	0.00338	1	0.04236	1	0.00034	0.208	0.0053099	1	2e-05	0.0138
18p loss	107 (29%)	262	9.9999e-06	0.0079	0.63081	1	0.50463	1	0.62003	1	0.39351	1	0.25817	1	0.18682	1	0.42177	1	0.36315	1	0.20748	1
18q loss	132 (36%)	237	9.9999e-06	0.0079	0.02667	1	0.29353	1	0.86798	1	0.0070799	1	0.02254	1	0.0051399	1	0.00329	1	0.01398	1	0.00129	0.735
19p loss	93 (25%)	276	9.9999e-06	0.0079	9.9999e-06	0.0079	0.00397	1	0.070229	1	9.9999e-06	0.0079	9.9999e-06	0.0079	9.9999e-06	0.0079	9.9999e-06	0.0079	9.9999e-06	0.0079	9.9999e-06	0.0079
19q loss	72 (20%)	297	9.9999e-06	0.0079	9.9999e-06	0.0079	0.01799	1	0.14351	1	9.9999e-06	0.0079	3e-05	0.0204	9.9999e-06	0.0079	9.9999e-06	0.0079	9.9999e-06	0.0079	9.9999e-06	0.0079
20p loss	19 (5%)	350	0.00033	0.203	0.00036	0.22	1	1	0.3702	1	0.00044	0.266	0.057419	1	0.10628	1	0.64636	1	0.43566	1	0.58754	1
21q loss	143 (39%)	226	9.9999e-06	0.0079	0.02317	1	0.1011	1	0.2969	1	0.03695	1	0.00167	0.92	0.00039	0.238	0.0052599	1	0.00015	0.0966	0.00198	1
22q loss	116 (31%)	253	9.9999e-06	0.0079	9.9999e-06	0.0079	0.01497	1	0.0071399	1	0.00125	0.715	0.00432	1	4e-05	0.0268	9.9999e-06	0.0079	4e-04	0.243	9.9999e-06	0.0079
xq loss	43 (12%)	326	9.9999e-06	0.0079	4e-05	0.0268	0.2635	1	0.069589	1	0.057209	1	0.15787	1	0.04579	1	0.79487	1	0.04858	1	0.18579	1
