Correlation between copy number variation genes (focal events) and selected clinical features
Overview
Introduction

This pipeline computes the correlation between significant copy number variation (cnv focal) genes and selected clinical features.

Summary

Testing the association between copy number variation 99 focal events and 7 clinical features across 485 patients, 171 significant findings detected with Q value < 0.25.

  • amp_1p35.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_1p34.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_1q21.3 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_1q22 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_2p24.3 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • amp_2q13 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_3p25.1 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_3p14.1 cnv correlated to 'Time to Death' and 'HISTOLOGICAL.TYPE'.

  • amp_3q26.2 cnv correlated to 'AGE',  'HISTOLOGICAL.TYPE', and 'RACE'.

  • amp_3q26.2 cnv correlated to 'AGE',  'HISTOLOGICAL.TYPE', and 'RACE'.

  • amp_4p16.3 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_5p15.33 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_5q35.3 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_6p24.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_6q25.1 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • amp_8p11.21 cnv correlated to 'Time to Death' and 'HISTOLOGICAL.TYPE'.

  • amp_8q24.21 cnv correlated to 'Time to Death' and 'HISTOLOGICAL.TYPE'.

  • amp_8q24.21 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • amp_9p24.2 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • amp_9q34.3 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • amp_11p11.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_11q13.2 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • amp_11q14.1 cnv correlated to 'Time to Death' and 'HISTOLOGICAL.TYPE'.

  • amp_12p12.1 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • amp_12q13.11 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • amp_12q13.2 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • amp_13q34 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_14q24.3 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • amp_15q26.3 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • amp_16p11.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_17q11.2 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • amp_17q12 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_17q25.1 cnv correlated to 'AGE',  'HISTOLOGICAL.TYPE', and 'RACE'.

  • amp_18p11.31 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_18q11.2 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • amp_19p13.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_19p13.12 cnv correlated to 'AGE',  'HISTOLOGICAL.TYPE', and 'RACE'.

  • amp_19q12 cnv correlated to 'Time to Death',  'AGE',  'HISTOLOGICAL.TYPE', and 'RACE'.

  • amp_20p13 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_20q11.21 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_20q13.12 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_20q13.33 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • amp_22q12.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_1p36.21 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_1p36.11 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_2q22.1 cnv correlated to 'Time to Death' and 'HISTOLOGICAL.TYPE'.

  • del_2q37.3 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • del_3p14.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_3q13.31 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • del_4p16.3 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_4p15.31 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_4q22.1 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_4q34.3 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_5q11.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_6q26 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • del_7p22.3 cnv correlated to 'Time to Death',  'AGE', and 'HISTOLOGICAL.TYPE'.

  • del_7q11.22 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_7q31.1 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_7q36.1 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_8p23.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_8p21.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_9p23 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • del_9q21.2 cnv correlated to 'Time to Death',  'AGE', and 'HISTOLOGICAL.TYPE'.

  • del_9q34.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_10q23.31 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • del_11p15.5 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_11q14.1 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_11q25 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_12q23.1 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • del_12q24.33 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_13q11 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • del_13q14.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_14q13.1 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • del_15q15.1 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_15q23 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_16p13.3 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_16q21 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_16q23.1 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_17p13.3 cnv correlated to 'Time to Death',  'AGE', and 'HISTOLOGICAL.TYPE'.

  • del_17p11.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_17p11.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_17q11.2 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_17q21.31 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_18q21.2 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • del_18q23 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • del_19p13.3 cnv correlated to 'Time to Death',  'AGE', and 'HISTOLOGICAL.TYPE'.

  • del_19p12 cnv correlated to 'HISTOLOGICAL.TYPE'.

  • del_19q13.43 cnv correlated to 'Time to Death' and 'HISTOLOGICAL.TYPE'.

  • del_20p12.1 cnv correlated to 'Time to Death' and 'HISTOLOGICAL.TYPE'.

  • del_22q11.1 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_22q13.31 cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • del_xp21.1 cnv correlated to 'Time to Death',  'AGE', and 'HISTOLOGICAL.TYPE'.

Results
Overview of the results

Table 1.  Get Full Table Overview of the association between significant copy number variation of 99 focal events and 7 clinical features. Shown in the table are P values (Q values). Thresholded by Q value < 0.25, 171 significant findings detected.

Clinical
Features 		Time
to
Death 		AGE HISTOLOGICAL
TYPE 		RADIATIONS
RADIATION
REGIMENINDICATION 		COMPLETENESS
OF
RESECTION 		RACE ETHNICITY
nCNV (%) nWild-Type logrank test Wilcoxon-test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test
amp 19q12 100 (21%) 385 0.000266
(0.143) 		1.05e-08
(7.18e-06) 		1e-05
(0.00662) 		0.456
(1.00) 		0.148
(1.00) 		1e-05
(0.00662) 		0.726
(1.00)
amp 3q26 2 150 (31%) 335 0.00617
(1.00) 		1.26e-10
(8.72e-08) 		1e-05
(0.00662) 		0.103
(1.00) 		0.181
(1.00) 		0.00012
(0.0662) 		0.761
(1.00)
amp 3q26 2 141 (29%) 344 0.00523
(1.00) 		1.27e-08
(8.68e-06) 		1e-05
(0.00662) 		0.122
(1.00) 		0.118
(1.00) 		0.00025
(0.135) 		0.365
(1.00)
amp 17q25 1 89 (18%) 396 0.00457
(1.00) 		0.000275
(0.148) 		1e-05
(0.00662) 		0.604
(1.00) 		0.129
(1.00) 		3e-05
(0.017) 		0.476
(1.00)
amp 19p13 12 85 (18%) 400 0.00783
(1.00) 		1.22e-10
(8.41e-08) 		1e-05
(0.00662) 		0.0339
(1.00) 		0.233
(1.00) 		0.00046
(0.241) 		0.706
(1.00)
del 7p22 3 64 (13%) 421 0.000273
(0.147) 		3.29e-05
(0.0185) 		1e-05
(0.00662) 		0.237
(1.00) 		0.222
(1.00) 		0.0348
(1.00) 		1
(1.00)
del 9q21 2 111 (23%) 374 0.000466
(0.244) 		1.16e-10
(8.01e-08) 		1e-05
(0.00662) 		0.284
(1.00) 		0.154
(1.00) 		0.0668
(1.00) 		0.501
(1.00)
del 17p13 3 102 (21%) 383 0.000403
(0.214) 		9.52e-05
(0.0528) 		1e-05
(0.00662) 		0.174
(1.00) 		0.0889
(1.00) 		0.0165
(1.00) 		0.742
(1.00)
del 19p13 3 133 (27%) 352 4.5e-06
(0.00299) 		2.12e-11
(1.47e-08) 		1e-05
(0.00662) 		0.143
(1.00) 		0.00224
(1.00) 		0.00084
(0.429) 		0.201
(1.00)
del xp21 1 75 (15%) 410 0.000453
(0.238) 		0.000212
(0.116) 		1e-05
(0.00662) 		0.266
(1.00) 		0.132
(1.00) 		0.00117
(0.589) 		0.125
(1.00)
amp 1p35 2 50 (10%) 435 0.145
(1.00) 		0.000208
(0.113) 		1e-05
(0.00662) 		0.869
(1.00) 		0.514
(1.00) 		0.0541
(1.00) 		0.353
(1.00)
amp 1p34 2 64 (13%) 421 0.0325
(1.00) 		0.000126
(0.0696) 		1e-05
(0.00662) 		0.237
(1.00) 		0.0438
(1.00) 		0.0132
(1.00) 		0.667
(1.00)
amp 1q21 3 216 (45%) 269 0.0334
(1.00) 		1.59e-05
(0.00906) 		2e-05
(0.0114) 		0.418
(1.00) 		0.692
(1.00) 		0.00649
(1.00) 		0.4
(1.00)
amp 1q22 230 (47%) 255 0.00329
(1.00) 		3.82e-07
(0.000258) 		1e-05
(0.00662) 		0.42
(1.00) 		0.277
(1.00) 		0.00875
(1.00) 		0.579
(1.00)
amp 2q13 105 (22%) 380 0.00156
(0.772) 		0.000185
(0.102) 		1e-05
(0.00662) 		0.393
(1.00) 		0.185
(1.00) 		0.0899
(1.00) 		1
(1.00)
amp 3p25 1 70 (14%) 415 0.0241
(1.00) 		0.000386
(0.205) 		1e-05
(0.00662) 		0.115
(1.00) 		0.696
(1.00) 		0.0168
(1.00) 		0.41
(1.00)
amp 3p14 1 55 (11%) 430 0.00037
(0.197) 		0.013
(1.00) 		2e-05
(0.0114) 		0.0387
(1.00) 		0.212
(1.00) 		0.0178
(1.00) 		0.0454
(1.00)
amp 4p16 3 49 (10%) 436 0.166
(1.00) 		1.87e-05
(0.0106) 		1e-05
(0.00662) 		0.74
(1.00) 		0.231
(1.00) 		0.339
(1.00) 		0.309
(1.00)
amp 5p15 33 78 (16%) 407 0.00205
(0.992) 		0.000194
(0.106) 		1e-05
(0.00662) 		0.172
(1.00) 		0.125
(1.00) 		0.00737
(1.00) 		0.24
(1.00)
amp 5q35 3 47 (10%) 438 0.0942
(1.00) 		0.000191
(0.104) 		1e-05
(0.00662) 		0.173
(1.00) 		0.398
(1.00) 		0.0349
(1.00) 		0.376
(1.00)
amp 6p24 2 102 (21%) 383 0.253
(1.00) 		8.99e-07
(0.000603) 		1e-05
(0.00662) 		0.0855
(1.00) 		0.666
(1.00) 		0.306
(1.00) 		1
(1.00)
amp 8p11 21 145 (30%) 340 3.04e-05
(0.0172) 		0.79
(1.00) 		1e-05
(0.00662) 		0.0278
(1.00) 		0.00556
(1.00) 		0.448
(1.00) 		0.762
(1.00)
amp 8q24 21 184 (38%) 301 0.000244
(0.133) 		0.0719
(1.00) 		1e-05
(0.00662) 		0.0127
(1.00) 		0.178
(1.00) 		0.375
(1.00) 		0.579
(1.00)
amp 11p11 2 45 (9%) 440 0.0102
(1.00) 		8.94e-05
(0.0497) 		1e-05
(0.00662) 		0.863
(1.00) 		0.347
(1.00) 		0.29
(1.00) 		0.295
(1.00)
amp 11q14 1 51 (11%) 434 0.000119
(0.0658) 		0.00909
(1.00) 		1e-05
(0.00662) 		0.188
(1.00) 		0.248
(1.00) 		0.117
(1.00) 		1
(1.00)
amp 13q34 53 (11%) 432 0.41
(1.00) 		3.37e-05
(0.0189) 		1e-05
(0.00662) 		1
(1.00) 		0.0104
(1.00) 		0.0243
(1.00) 		1
(1.00)
amp 16p11 2 57 (12%) 428 0.00138
(0.69) 		0.000326
(0.174) 		1e-05
(0.00662) 		0.536
(1.00) 		0.04
(1.00) 		0.217
(1.00) 		0.656
(1.00)
amp 17q12 65 (13%) 420 0.00191
(0.929) 		0.000357
(0.19) 		1e-05
(0.00662) 		0.883
(1.00) 		0.121
(1.00) 		0.00613
(1.00) 		1
(1.00)
amp 18p11 31 83 (17%) 402 0.0625
(1.00) 		5.28e-05
(0.0295) 		1e-05
(0.00662) 		0.0229
(1.00) 		0.0109
(1.00) 		0.00219
(1.00) 		1
(1.00)
amp 19p13 2 81 (17%) 404 0.086
(1.00) 		3e-10
(2.07e-07) 		1e-05
(0.00662) 		0.345
(1.00) 		0.372
(1.00) 		0.0358
(1.00) 		0.701
(1.00)
amp 20p13 103 (21%) 382 0.302
(1.00) 		1.13e-06
(0.000755) 		1e-05
(0.00662) 		0.0486
(1.00) 		0.503
(1.00) 		0.0698
(1.00) 		0.478
(1.00)
amp 20q11 21 127 (26%) 358 0.00084
(0.429) 		3.71e-08
(2.51e-05) 		1e-05
(0.00662) 		0.022
(1.00) 		0.074
(1.00) 		0.00375
(1.00) 		0.321
(1.00)
amp 20q13 12 131 (27%) 354 0.00695
(1.00) 		2.22e-08
(1.51e-05) 		1e-05
(0.00662) 		0.00308
(1.00) 		0.0431
(1.00) 		0.0284
(1.00) 		0.348
(1.00)
amp 20q13 33 126 (26%) 359 0.0188
(1.00) 		7.28e-08
(4.93e-05) 		1e-05
(0.00662) 		0.00129
(0.645) 		0.0242
(1.00) 		0.0701
(1.00) 		0.746
(1.00)
amp 22q12 2 54 (11%) 431 0.00126
(0.632) 		0.000405
(0.214) 		1e-05
(0.00662) 		0.109
(1.00) 		0.0005
(0.26) 		0.0304
(1.00) 		0.641
(1.00)
del 1p36 21 60 (12%) 425 0.582
(1.00) 		7.06e-05
(0.0393) 		1e-05
(0.00662) 		0.762
(1.00) 		0.418
(1.00) 		0.104
(1.00) 		0.168
(1.00)
del 1p36 11 72 (15%) 413 0.0525
(1.00) 		1.57e-05
(0.00898) 		1e-05
(0.00662) 		0.572
(1.00) 		0.0259
(1.00) 		0.0741
(1.00) 		0.112
(1.00)
del 2q22 1 43 (9%) 442 6.89e-09
(4.73e-06) 		0.00297
(1.00) 		1e-05
(0.00662) 		0.00238
(1.00) 		0.00284
(1.00) 		0.0273
(1.00) 		1
(1.00)
del 3p14 2 67 (14%) 418 0.184
(1.00) 		0.000404
(0.214) 		1e-05
(0.00662) 		0.466
(1.00) 		0.728
(1.00) 		0.0217
(1.00) 		0.229
(1.00)
del 4p16 3 78 (16%) 407 0.00606
(1.00) 		0.000115
(0.0636) 		1e-05
(0.00662) 		0.414
(1.00) 		0.766
(1.00) 		0.321
(1.00) 		0.707
(1.00)
del 4p15 31 82 (17%) 403 0.0108
(1.00) 		5.77e-05
(0.0322) 		1e-05
(0.00662) 		0.18
(1.00) 		0.385
(1.00) 		0.31
(1.00) 		0.254
(1.00)
del 4q22 1 90 (19%) 395 0.00594
(1.00) 		9.98e-06
(0.00662) 		1e-05
(0.00662) 		0.247
(1.00) 		0.0467
(1.00) 		0.157
(1.00) 		0.711
(1.00)
del 4q34 3 113 (23%) 372 0.0276
(1.00) 		5.9e-07
(0.000397) 		1e-05
(0.00662) 		0.236
(1.00) 		0.112
(1.00) 		0.0102
(1.00) 		1
(1.00)
del 5q11 2 97 (20%) 388 0.028
(1.00) 		5.64e-06
(0.00374) 		1e-05
(0.00662) 		0.382
(1.00) 		0.579
(1.00) 		0.0599
(1.00) 		0.153
(1.00)
del 7q11 22 38 (8%) 447 0.794
(1.00) 		1.17e-05
(0.00669) 		1e-05
(0.00662) 		0.352
(1.00) 		0.632
(1.00) 		0.155
(1.00) 		1
(1.00)
del 7q31 1 48 (10%) 437 0.0459
(1.00) 		1.44e-05
(0.00823) 		1e-05
(0.00662) 		1
(1.00) 		0.391
(1.00) 		0.139
(1.00) 		1
(1.00)
del 7q36 1 58 (12%) 427 0.0101
(1.00) 		2.61e-08
(1.78e-05) 		1e-05
(0.00662) 		0.877
(1.00) 		0.252
(1.00) 		0.124
(1.00) 		1
(1.00)
del 8p23 2 101 (21%) 384 0.00276
(1.00) 		3.15e-05
(0.0177) 		1e-05
(0.00662) 		0.266
(1.00) 		0.0192
(1.00) 		0.00502
(1.00) 		0.48
(1.00)
del 8p21 2 99 (20%) 386 0.0124
(1.00) 		3.63e-06
(0.00242) 		1e-05
(0.00662) 		0.32
(1.00) 		0.0738
(1.00) 		0.00712
(1.00) 		1
(1.00)
del 9q34 2 114 (24%) 371 0.00378
(1.00) 		5.57e-09
(3.83e-06) 		1e-05
(0.00662) 		0.154
(1.00) 		0.118
(1.00) 		0.106
(1.00) 		1
(1.00)
del 11p15 5 87 (18%) 398 0.0237
(1.00) 		4.25e-06
(0.00283) 		1e-05
(0.00662) 		0.0253
(1.00) 		0.0825
(1.00) 		0.0588
(1.00) 		0.285
(1.00)
del 11q14 1 59 (12%) 426 0.00998
(1.00) 		0.000246
(0.133) 		1e-05
(0.00662) 		0.166
(1.00) 		0.494
(1.00) 		0.166
(1.00) 		0.0239
(1.00)
del 11q25 82 (17%) 403 0.0018
(0.88) 		0.000188
(0.103) 		1e-05
(0.00662) 		0.00478
(1.00) 		0.313
(1.00) 		0.071
(1.00) 		0.709
(1.00)
del 12q24 33 54 (11%) 431 0.063
(1.00) 		0.000125
(0.0689) 		1e-05
(0.00662) 		0.0537
(1.00) 		0.0218
(1.00) 		0.378
(1.00) 		1
(1.00)
del 13q14 2 86 (18%) 399 0.0102
(1.00) 		0.00031
(0.166) 		1e-05
(0.00662) 		0.0255
(1.00) 		0.401
(1.00) 		0.304
(1.00) 		0.145
(1.00)
del 15q15 1 121 (25%) 364 0.00242
(1.00) 		1.29e-08
(8.83e-06) 		1e-05
(0.00662) 		0.0359
(1.00) 		0.0284
(1.00) 		0.0353
(1.00) 		1
(1.00)
del 15q23 101 (21%) 384 0.021
(1.00) 		3.29e-06
(0.0022) 		1e-05
(0.00662) 		0.107
(1.00) 		0.312
(1.00) 		0.0901
(1.00) 		0.482
(1.00)
del 16p13 3 78 (16%) 407 0.0157
(1.00) 		2.45e-07
(0.000165) 		1e-05
(0.00662) 		0.172
(1.00) 		0.0734
(1.00) 		0.0289
(1.00) 		1
(1.00)
del 16q21 135 (28%) 350 0.0268
(1.00) 		4.58e-09
(3.15e-06) 		1e-05
(0.00662) 		0.178
(1.00) 		0.198
(1.00) 		0.0139
(1.00) 		1
(1.00)
del 16q23 1 144 (30%) 341 0.00795
(1.00) 		1.87e-08
(1.27e-05) 		1e-05
(0.00662) 		0.322
(1.00) 		0.0102
(1.00) 		0.00325
(1.00) 		1
(1.00)
del 17p11 2 108 (22%) 377 0.000491
(0.256) 		7.22e-07
(0.000485) 		1e-05
(0.00662) 		0.184
(1.00) 		0.429
(1.00) 		0.0575
(1.00) 		1
(1.00)
del 17p11 2 102 (21%) 383 0.000702
(0.362) 		1.94e-06
(0.0013) 		1e-05
(0.00662) 		0.387
(1.00) 		0.623
(1.00) 		0.0563
(1.00) 		1
(1.00)
del 17q11 2 90 (19%) 395 0.0374
(1.00) 		5.35e-07
(0.00036) 		1e-05
(0.00662) 		0.157
(1.00) 		0.191
(1.00) 		0.869
(1.00) 		0.716
(1.00)
del 17q21 31 89 (18%) 396 0.00889
(1.00) 		1.95e-05
(0.0111) 		1e-05
(0.00662) 		0.119
(1.00) 		0.365
(1.00) 		0.498
(1.00) 		0.0194
(1.00)
del 19q13 43 56 (12%) 429 0.000453
(0.238) 		0.000609
(0.315) 		1e-05
(0.00662) 		0.638
(1.00) 		0.0297
(1.00) 		0.325
(1.00) 		0.149
(1.00)
del 20p12 1 31 (6%) 454 4.43e-05
(0.0248) 		0.21
(1.00) 		0.00023
(0.125) 		1
(1.00) 		0.0516
(1.00) 		0.198
(1.00) 		0.251
(1.00)
del 22q11 1 73 (15%) 412 0.0052
(1.00) 		0.000278
(0.149) 		1e-05
(0.00662) 		0.0341
(1.00) 		0.724
(1.00) 		0.195
(1.00) 		0.0505
(1.00)
del 22q13 31 118 (24%) 367 0.00214
(1.00) 		1.06e-08
(7.27e-06) 		1e-05
(0.00662) 		0.0796
(1.00) 		0.613
(1.00) 		0.00461
(1.00) 		0.0976
(1.00)
amp 2p24 3 107 (22%) 378 0.000671
(0.346) 		0.0133
(1.00) 		1e-05
(0.00662) 		0.0517
(1.00) 		0.742
(1.00) 		0.436
(1.00) 		0.312
(1.00)
amp 6q25 1 76 (16%) 409 0.295
(1.00) 		0.00214
(1.00) 		1e-05
(0.00662) 		0.337
(1.00) 		0.266
(1.00) 		0.0036
(1.00) 		0.702
(1.00)
amp 8q24 21 192 (40%) 293 0.000646
(0.334) 		0.0203
(1.00) 		1e-05
(0.00662) 		0.00544
(1.00) 		0.0126
(1.00) 		0.627
(1.00) 		1
(1.00)
amp 9p24 2 57 (12%) 428 0.012
(1.00) 		0.000829
(0.424) 		1e-05
(0.00662) 		0.213
(1.00) 		0.245
(1.00) 		0.109
(1.00) 		0.0111
(1.00)
amp 9q34 3 34 (7%) 451 0.0122
(1.00) 		0.00115
(0.58) 		1e-05
(0.00662) 		0.847
(1.00) 		0.272
(1.00) 		0.0196
(1.00) 		1
(1.00)
amp 11q13 2 62 (13%) 423 0.028
(1.00) 		0.0017
(0.835) 		1e-05
(0.00662) 		0.763
(1.00) 		0.148
(1.00) 		0.899
(1.00) 		1
(1.00)
amp 12p12 1 81 (17%) 404 0.698
(1.00) 		0.111
(1.00) 		1e-05
(0.00662) 		0.5
(1.00) 		0.702
(1.00) 		0.102
(1.00) 		0.138
(1.00)
amp 12q13 11 77 (16%) 408 0.524
(1.00) 		0.56
(1.00) 		1e-05
(0.00662) 		0.129
(1.00) 		0.369
(1.00) 		0.00492
(1.00) 		0.701
(1.00)
amp 12q13 2 88 (18%) 397 0.574
(1.00) 		0.0753
(1.00) 		1e-05
(0.00662) 		0.0371
(1.00) 		0.0876
(1.00) 		0.0451
(1.00) 		1
(1.00)
amp 14q24 3 58 (12%) 427 0.00113
(0.572) 		0.000912
(0.464) 		1e-05
(0.00662) 		0.12
(1.00) 		0.373
(1.00) 		0.527
(1.00) 		0.656
(1.00)
amp 15q26 3 33 (7%) 452 0.0554
(1.00) 		0.0143
(1.00) 		3e-05
(0.017) 		0.231
(1.00) 		0.0159
(1.00) 		0.602
(1.00) 		0.266
(1.00)
amp 17q11 2 64 (13%) 421 0.0172
(1.00) 		0.00304
(1.00) 		1e-05
(0.00662) 		0.376
(1.00) 		0.00079
(0.405) 		0.00393
(1.00) 		0.207
(1.00)
amp 18q11 2 63 (13%) 422 0.0155
(1.00) 		0.00159
(0.782) 		1e-05
(0.00662) 		0.295
(1.00) 		0.0275
(1.00) 		0.00577
(1.00) 		1
(1.00)
del 2q37 3 47 (10%) 438 0.0669
(1.00) 		0.00165
(0.813) 		0.00044
(0.232) 		0.173
(1.00) 		0.0473
(1.00) 		0.113
(1.00) 		1
(1.00)
del 3q13 31 28 (6%) 457 0.747
(1.00) 		0.0018
(0.88) 		1e-05
(0.00662) 		0.519
(1.00) 		0.686
(1.00) 		0.5
(1.00) 		1
(1.00)
del 6q26 41 (8%) 444 0.209
(1.00) 		0.00295
(1.00) 		1e-05
(0.00662) 		0.593
(1.00) 		0.972
(1.00) 		0.857
(1.00) 		0.61
(1.00)
del 9p23 64 (13%) 421 0.105
(1.00) 		0.00236
(1.00) 		1e-05
(0.00662) 		0.138
(1.00) 		0.179
(1.00) 		0.439
(1.00) 		1
(1.00)
del 10q23 31 66 (14%) 419 0.0935
(1.00) 		0.000982
(0.499) 		1e-05
(0.00662) 		0.012
(1.00) 		0.118
(1.00) 		0.245
(1.00) 		0.69
(1.00)
del 12q23 1 45 (9%) 440 0.0177
(1.00) 		0.00143
(0.709) 		1e-05
(0.00662) 		0.118
(1.00) 		0.022
(1.00) 		0.0174
(1.00) 		1
(1.00)
del 13q11 81 (17%) 404 0.00773
(1.00) 		0.000484
(0.253) 		1e-05
(0.00662) 		0.108
(1.00) 		0.13
(1.00) 		0.196
(1.00) 		0.25
(1.00)
del 14q13 1 62 (13%) 423 0.00828
(1.00) 		0.00106
(0.538) 		1e-05
(0.00662) 		0.456
(1.00) 		0.964
(1.00) 		0.0114
(1.00) 		0.187
(1.00)
del 18q21 2 77 (16%) 408 0.451
(1.00) 		0.000538
(0.279) 		1e-05
(0.00662) 		0.0133
(1.00) 		0.118
(1.00) 		0.0534
(1.00) 		0.25
(1.00)
del 18q23 83 (17%) 402 0.00329
(1.00) 		0.00122
(0.611) 		1e-05
(0.00662) 		0.00194
(0.941) 		0.0102
(1.00) 		0.0832
(1.00) 		0.0612
(1.00)
del 19p12 47 (10%) 438 0.00774
(1.00) 		0.0333
(1.00) 		1e-05
(0.00662) 		0.0877
(1.00) 		0.0703
(1.00) 		0.244
(1.00) 		0.628
(1.00)
amp 1p22 3 86 (18%) 399 0.528
(1.00) 		0.00142
(0.704) 		0.00139
(0.692) 		0.599
(1.00) 		0.912
(1.00) 		0.503
(1.00) 		0.237
(1.00)
amp 1q44 199 (41%) 286 0.138
(1.00) 		0.00767
(1.00) 		0.497
(1.00) 		0.61
(1.00) 		0.309
(1.00) 		0.215
(1.00) 		0.57
(1.00)
amp 7q22 1 80 (16%) 405 0.00153
(0.757) 		0.0146
(1.00) 		0.00187
(0.913) 		0.0778
(1.00) 		0.674
(1.00) 		0.959
(1.00) 		1
(1.00)
amp 10q22 2 132 (27%) 353 0.369
(1.00) 		0.317
(1.00) 		0.00657
(1.00) 		0.498
(1.00) 		0.605
(1.00) 		0.54
(1.00) 		1
(1.00)
amp xp11 23 81 (17%) 404 0.259
(1.00) 		0.115
(1.00) 		0.00073
(0.375) 		0.031
(1.00) 		0.56
(1.00) 		0.968
(1.00) 		0.706
(1.00)
amp xq28 79 (16%) 406 0.0011
(0.558) 		0.124
(1.00) 		0.00433
(1.00) 		1
(1.00) 		0.203
(1.00) 		0.531
(1.00) 		0.433
(1.00)
del 2p25 3 23 (5%) 462 0.0266
(1.00) 		0.0831
(1.00) 		0.00589
(1.00) 		0.103
(1.00) 		0.262
(1.00) 		0.436
(1.00) 		1
(1.00)
'amp_1p35.2' versus 'AGE'

P value = 0.000208 (Wilcoxon-test), Q value = 0.11

Table S1.  Gene #1: 'amp_1p35.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 1(1P35.2) MUTATED 50 68.6 (9.0)
AMP PEAK 1(1P35.2) WILD-TYPE 434 63.2 (11.4)

Figure S1.  Get High-res Image Gene #1: 'amp_1p35.2' versus Clinical Feature #2: 'AGE'

'amp_1p35.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S2.  Gene #1: 'amp_1p35.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 1(1P35.2) MUTATED 14 5 31
AMP PEAK 1(1P35.2) WILD-TYPE 353 15 67

Figure S2.  Get High-res Image Gene #1: 'amp_1p35.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_1p34.2' versus 'AGE'

P value = 0.000126 (Wilcoxon-test), Q value = 0.07

Table S3.  Gene #2: 'amp_1p34.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 2(1P34.2) MUTATED 64 68.6 (9.8)
AMP PEAK 2(1P34.2) WILD-TYPE 420 63.0 (11.3)

Figure S3.  Get High-res Image Gene #2: 'amp_1p34.2' versus Clinical Feature #2: 'AGE'

'amp_1p34.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S4.  Gene #2: 'amp_1p34.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 2(1P34.2) MUTATED 18 7 39
AMP PEAK 2(1P34.2) WILD-TYPE 349 13 59

Figure S4.  Get High-res Image Gene #2: 'amp_1p34.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_1q21.3' versus 'AGE'

P value = 1.59e-05 (Wilcoxon-test), Q value = 0.0091

Table S5.  Gene #4: 'amp_1q21.3' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 4(1Q21.3) MUTATED 216 66.3 (10.4)
AMP PEAK 4(1Q21.3) WILD-TYPE 268 61.7 (11.6)

Figure S5.  Get High-res Image Gene #4: 'amp_1q21.3' versus Clinical Feature #2: 'AGE'

'amp_1q21.3' versus 'HISTOLOGICAL.TYPE'

P value = 2e-05 (Fisher's exact test), Q value = 0.011

Table S6.  Gene #4: 'amp_1q21.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 4(1Q21.3) MUTATED 143 10 63
AMP PEAK 4(1Q21.3) WILD-TYPE 224 10 35

Figure S6.  Get High-res Image Gene #4: 'amp_1q21.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_1q22' versus 'AGE'

P value = 3.82e-07 (Wilcoxon-test), Q value = 0.00026

Table S7.  Gene #5: 'amp_1q22' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 5(1Q22) MUTATED 230 66.5 (10.4)
AMP PEAK 5(1Q22) WILD-TYPE 254 61.2 (11.5)

Figure S7.  Get High-res Image Gene #5: 'amp_1q22' versus Clinical Feature #2: 'AGE'

'amp_1q22' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S8.  Gene #5: 'amp_1q22' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 5(1Q22) MUTATED 150 10 70
AMP PEAK 5(1Q22) WILD-TYPE 217 10 28

Figure S8.  Get High-res Image Gene #5: 'amp_1q22' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_2p24.3' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S9.  Gene #7: 'amp_2p24.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 7(2P24.3) MUTATED 52 7 48
AMP PEAK 7(2P24.3) WILD-TYPE 315 13 50

Figure S9.  Get High-res Image Gene #7: 'amp_2p24.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_2q13' versus 'AGE'

P value = 0.000185 (Wilcoxon-test), Q value = 0.1

Table S10.  Gene #8: 'amp_2q13' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 8(2Q13) MUTATED 104 67.1 (9.2)
AMP PEAK 8(2Q13) WILD-TYPE 380 62.8 (11.6)

Figure S10.  Get High-res Image Gene #8: 'amp_2q13' versus Clinical Feature #2: 'AGE'

'amp_2q13' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S11.  Gene #8: 'amp_2q13' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 8(2Q13) MUTATED 43 5 57
AMP PEAK 8(2Q13) WILD-TYPE 324 15 41

Figure S11.  Get High-res Image Gene #8: 'amp_2q13' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_3p25.1' versus 'AGE'

P value = 0.000386 (Wilcoxon-test), Q value = 0.2

Table S12.  Gene #9: 'amp_3p25.1' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 9(3P25.1) MUTATED 70 68.4 (10.7)
AMP PEAK 9(3P25.1) WILD-TYPE 414 63.0 (11.2)

Figure S12.  Get High-res Image Gene #9: 'amp_3p25.1' versus Clinical Feature #2: 'AGE'

'amp_3p25.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S13.  Gene #9: 'amp_3p25.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 9(3P25.1) MUTATED 31 1 38
AMP PEAK 9(3P25.1) WILD-TYPE 336 19 60

Figure S13.  Get High-res Image Gene #9: 'amp_3p25.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_3p14.1' versus 'Time to Death'

P value = 0.00037 (logrank test), Q value = 0.2

Table S14.  Gene #10: 'amp_3p14.1' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 483 60 0.0 - 191.8 (22.8)
AMP PEAK 10(3P14.1) MUTATED 54 15 0.1 - 191.8 (23.9)
AMP PEAK 10(3P14.1) WILD-TYPE 429 45 0.0 - 185.8 (22.8)

Figure S14.  Get High-res Image Gene #10: 'amp_3p14.1' versus Clinical Feature #1: 'Time to Death'

'amp_3p14.1' versus 'HISTOLOGICAL.TYPE'

P value = 2e-05 (Fisher's exact test), Q value = 0.011

Table S15.  Gene #10: 'amp_3p14.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 10(3P14.1) MUTATED 28 3 24
AMP PEAK 10(3P14.1) WILD-TYPE 339 17 74

Figure S15.  Get High-res Image Gene #10: 'amp_3p14.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_3q26.2' versus 'AGE'

P value = 1.26e-10 (Wilcoxon-test), Q value = 8.7e-08

Table S16.  Gene #11: 'amp_3q26.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 11(3Q26.2) MUTATED 150 68.3 (9.4)
AMP PEAK 11(3Q26.2) WILD-TYPE 334 61.7 (11.5)

Figure S16.  Get High-res Image Gene #11: 'amp_3q26.2' versus Clinical Feature #2: 'AGE'

'amp_3q26.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S17.  Gene #11: 'amp_3q26.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 11(3Q26.2) MUTATED 65 8 77
AMP PEAK 11(3Q26.2) WILD-TYPE 302 12 21

Figure S17.  Get High-res Image Gene #11: 'amp_3q26.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_3q26.2' versus 'RACE'

P value = 0.00012 (Fisher's exact test), Q value = 0.066

Table S18.  Gene #11: 'amp_3q26.2' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 19 73 9 355
AMP PEAK 11(3Q26.2) MUTATED 0 3 38 4 94
AMP PEAK 11(3Q26.2) WILD-TYPE 4 16 35 5 261

Figure S18.  Get High-res Image Gene #11: 'amp_3q26.2' versus Clinical Feature #6: 'RACE'

'amp_3q26.2' versus 'AGE'

P value = 1.27e-08 (Wilcoxon-test), Q value = 8.7e-06

Table S19.  Gene #12: 'amp_3q26.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 12(3Q26.2) MUTATED 141 68.0 (9.4)
AMP PEAK 12(3Q26.2) WILD-TYPE 343 62.0 (11.5)

Figure S19.  Get High-res Image Gene #12: 'amp_3q26.2' versus Clinical Feature #2: 'AGE'

'amp_3q26.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S20.  Gene #12: 'amp_3q26.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 12(3Q26.2) MUTATED 59 7 75
AMP PEAK 12(3Q26.2) WILD-TYPE 308 13 23

Figure S20.  Get High-res Image Gene #12: 'amp_3q26.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_3q26.2' versus 'RACE'

P value = 0.00025 (Fisher's exact test), Q value = 0.13

Table S21.  Gene #12: 'amp_3q26.2' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 19 73 9 355
AMP PEAK 12(3Q26.2) MUTATED 0 3 36 4 88
AMP PEAK 12(3Q26.2) WILD-TYPE 4 16 37 5 267

Figure S21.  Get High-res Image Gene #12: 'amp_3q26.2' versus Clinical Feature #6: 'RACE'

'amp_4p16.3' versus 'AGE'

P value = 1.87e-05 (Wilcoxon-test), Q value = 0.011

Table S22.  Gene #13: 'amp_4p16.3' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 13(4P16.3) MUTATED 49 69.7 (8.9)
AMP PEAK 13(4P16.3) WILD-TYPE 435 63.1 (11.3)

Figure S22.  Get High-res Image Gene #13: 'amp_4p16.3' versus Clinical Feature #2: 'AGE'

'amp_4p16.3' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S23.  Gene #13: 'amp_4p16.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 13(4P16.3) MUTATED 15 1 33
AMP PEAK 13(4P16.3) WILD-TYPE 352 19 65

Figure S23.  Get High-res Image Gene #13: 'amp_4p16.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_5p15.33' versus 'AGE'

P value = 0.000194 (Wilcoxon-test), Q value = 0.11

Table S24.  Gene #14: 'amp_5p15.33' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 14(5P15.33) MUTATED 78 67.5 (10.1)
AMP PEAK 14(5P15.33) WILD-TYPE 406 63.0 (11.3)

Figure S24.  Get High-res Image Gene #14: 'amp_5p15.33' versus Clinical Feature #2: 'AGE'

'amp_5p15.33' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S25.  Gene #14: 'amp_5p15.33' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 14(5P15.33) MUTATED 26 3 49
AMP PEAK 14(5P15.33) WILD-TYPE 341 17 49

Figure S25.  Get High-res Image Gene #14: 'amp_5p15.33' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_5q35.3' versus 'AGE'

P value = 0.000191 (Wilcoxon-test), Q value = 0.1

Table S26.  Gene #15: 'amp_5q35.3' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 15(5Q35.3) MUTATED 47 69.4 (10.5)
AMP PEAK 15(5Q35.3) WILD-TYPE 437 63.1 (11.2)

Figure S26.  Get High-res Image Gene #15: 'amp_5q35.3' versus Clinical Feature #2: 'AGE'

'amp_5q35.3' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S27.  Gene #15: 'amp_5q35.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 15(5Q35.3) MUTATED 18 2 27
AMP PEAK 15(5Q35.3) WILD-TYPE 349 18 71

Figure S27.  Get High-res Image Gene #15: 'amp_5q35.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_6p24.2' versus 'AGE'

P value = 8.99e-07 (Wilcoxon-test), Q value = 6e-04

Table S28.  Gene #16: 'amp_6p24.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 16(6P24.2) MUTATED 102 68.2 (10.0)
AMP PEAK 16(6P24.2) WILD-TYPE 382 62.5 (11.3)

Figure S28.  Get High-res Image Gene #16: 'amp_6p24.2' versus Clinical Feature #2: 'AGE'

'amp_6p24.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S29.  Gene #16: 'amp_6p24.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 16(6P24.2) MUTATED 40 5 57
AMP PEAK 16(6P24.2) WILD-TYPE 327 15 41

Figure S29.  Get High-res Image Gene #16: 'amp_6p24.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_6q25.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S30.  Gene #17: 'amp_6q25.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 17(6Q25.1) MUTATED 40 2 34
AMP PEAK 17(6Q25.1) WILD-TYPE 327 18 64

Figure S30.  Get High-res Image Gene #17: 'amp_6q25.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_8p11.21' versus 'Time to Death'

P value = 3.04e-05 (logrank test), Q value = 0.017

Table S31.  Gene #19: 'amp_8p11.21' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 483 60 0.0 - 191.8 (22.8)
AMP PEAK 19(8P11.21) MUTATED 144 30 0.0 - 125.4 (19.0)
AMP PEAK 19(8P11.21) WILD-TYPE 339 30 0.1 - 191.8 (24.4)

Figure S31.  Get High-res Image Gene #19: 'amp_8p11.21' versus Clinical Feature #1: 'Time to Death'

'amp_8p11.21' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S32.  Gene #19: 'amp_8p11.21' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 19(8P11.21) MUTATED 86 7 52
AMP PEAK 19(8P11.21) WILD-TYPE 281 13 46

Figure S32.  Get High-res Image Gene #19: 'amp_8p11.21' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_8q24.21' versus 'Time to Death'

P value = 0.000244 (logrank test), Q value = 0.13

Table S33.  Gene #20: 'amp_8q24.21' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 483 60 0.0 - 191.8 (22.8)
AMP PEAK 20(8Q24.21) MUTATED 183 34 0.0 - 191.8 (19.3)
AMP PEAK 20(8Q24.21) WILD-TYPE 300 26 0.1 - 185.8 (24.8)

Figure S33.  Get High-res Image Gene #20: 'amp_8q24.21' versus Clinical Feature #1: 'Time to Death'

'amp_8q24.21' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S34.  Gene #20: 'amp_8q24.21' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 20(8Q24.21) MUTATED 103 10 71
AMP PEAK 20(8Q24.21) WILD-TYPE 264 10 27

Figure S34.  Get High-res Image Gene #20: 'amp_8q24.21' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_8q24.21' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S35.  Gene #21: 'amp_8q24.21' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 21(8Q24.21) MUTATED 108 9 75
AMP PEAK 21(8Q24.21) WILD-TYPE 259 11 23

Figure S35.  Get High-res Image Gene #21: 'amp_8q24.21' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_9p24.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S36.  Gene #22: 'amp_9p24.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 22(9P24.2) MUTATED 23 3 31
AMP PEAK 22(9P24.2) WILD-TYPE 344 17 67

Figure S36.  Get High-res Image Gene #22: 'amp_9p24.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_9q34.3' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S37.  Gene #23: 'amp_9q34.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 23(9Q34.3) MUTATED 12 4 18
AMP PEAK 23(9Q34.3) WILD-TYPE 355 16 80

Figure S37.  Get High-res Image Gene #23: 'amp_9q34.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_11p11.2' versus 'AGE'

P value = 8.94e-05 (Wilcoxon-test), Q value = 0.05

Table S38.  Gene #25: 'amp_11p11.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 25(11P11.2) MUTATED 45 69.9 (9.3)
AMP PEAK 25(11P11.2) WILD-TYPE 439 63.1 (11.3)

Figure S38.  Get High-res Image Gene #25: 'amp_11p11.2' versus Clinical Feature #2: 'AGE'

'amp_11p11.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S39.  Gene #25: 'amp_11p11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 25(11P11.2) MUTATED 15 4 26
AMP PEAK 25(11P11.2) WILD-TYPE 352 16 72

Figure S39.  Get High-res Image Gene #25: 'amp_11p11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_11q13.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S40.  Gene #26: 'amp_11q13.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 26(11Q13.2) MUTATED 29 3 30
AMP PEAK 26(11Q13.2) WILD-TYPE 338 17 68

Figure S40.  Get High-res Image Gene #26: 'amp_11q13.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_11q14.1' versus 'Time to Death'

P value = 0.000119 (logrank test), Q value = 0.066

Table S41.  Gene #27: 'amp_11q14.1' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 483 60 0.0 - 191.8 (22.8)
AMP PEAK 27(11Q14.1) MUTATED 51 14 0.0 - 102.3 (18.2)
AMP PEAK 27(11Q14.1) WILD-TYPE 432 46 0.1 - 191.8 (23.3)

Figure S41.  Get High-res Image Gene #27: 'amp_11q14.1' versus Clinical Feature #1: 'Time to Death'

'amp_11q14.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S42.  Gene #27: 'amp_11q14.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 27(11Q14.1) MUTATED 20 1 30
AMP PEAK 27(11Q14.1) WILD-TYPE 347 19 68

Figure S42.  Get High-res Image Gene #27: 'amp_11q14.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_12p12.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S43.  Gene #28: 'amp_12p12.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 28(12P12.1) MUTATED 40 4 37
AMP PEAK 28(12P12.1) WILD-TYPE 327 16 61

Figure S43.  Get High-res Image Gene #28: 'amp_12p12.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_12q13.11' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S44.  Gene #29: 'amp_12q13.11' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 29(12Q13.11) MUTATED 38 4 35
AMP PEAK 29(12Q13.11) WILD-TYPE 329 16 63

Figure S44.  Get High-res Image Gene #29: 'amp_12q13.11' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_12q13.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S45.  Gene #30: 'amp_12q13.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 30(12Q13.2) MUTATED 46 4 38
AMP PEAK 30(12Q13.2) WILD-TYPE 321 16 60

Figure S45.  Get High-res Image Gene #30: 'amp_12q13.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_13q34' versus 'AGE'

P value = 3.37e-05 (Wilcoxon-test), Q value = 0.019

Table S46.  Gene #31: 'amp_13q34' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 31(13Q34) MUTATED 53 69.3 (7.5)
AMP PEAK 31(13Q34) WILD-TYPE 431 63.1 (11.5)

Figure S46.  Get High-res Image Gene #31: 'amp_13q34' versus Clinical Feature #2: 'AGE'

'amp_13q34' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S47.  Gene #31: 'amp_13q34' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 31(13Q34) MUTATED 14 4 35
AMP PEAK 31(13Q34) WILD-TYPE 353 16 63

Figure S47.  Get High-res Image Gene #31: 'amp_13q34' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_14q24.3' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S48.  Gene #32: 'amp_14q24.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 32(14Q24.3) MUTATED 20 4 34
AMP PEAK 32(14Q24.3) WILD-TYPE 347 16 64

Figure S48.  Get High-res Image Gene #32: 'amp_14q24.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_15q26.3' versus 'HISTOLOGICAL.TYPE'

P value = 3e-05 (Fisher's exact test), Q value = 0.017

Table S49.  Gene #33: 'amp_15q26.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 33(15Q26.3) MUTATED 15 0 18
AMP PEAK 33(15Q26.3) WILD-TYPE 352 20 80

Figure S49.  Get High-res Image Gene #33: 'amp_15q26.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_16p11.2' versus 'AGE'

P value = 0.000326 (Wilcoxon-test), Q value = 0.17

Table S50.  Gene #34: 'amp_16p11.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 34(16P11.2) MUTATED 57 68.3 (8.8)
AMP PEAK 34(16P11.2) WILD-TYPE 427 63.1 (11.4)

Figure S50.  Get High-res Image Gene #34: 'amp_16p11.2' versus Clinical Feature #2: 'AGE'

'amp_16p11.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S51.  Gene #34: 'amp_16p11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 34(16P11.2) MUTATED 19 2 36
AMP PEAK 34(16P11.2) WILD-TYPE 348 18 62

Figure S51.  Get High-res Image Gene #34: 'amp_16p11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_17q11.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S52.  Gene #35: 'amp_17q11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 35(17Q11.2) MUTATED 15 6 43
AMP PEAK 35(17Q11.2) WILD-TYPE 352 14 55

Figure S52.  Get High-res Image Gene #35: 'amp_17q11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_17q12' versus 'AGE'

P value = 0.000357 (Wilcoxon-test), Q value = 0.19

Table S53.  Gene #36: 'amp_17q12' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 36(17Q12) MUTATED 65 68.6 (9.4)
AMP PEAK 36(17Q12) WILD-TYPE 419 63.0 (11.4)

Figure S53.  Get High-res Image Gene #36: 'amp_17q12' versus Clinical Feature #2: 'AGE'

'amp_17q12' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S54.  Gene #36: 'amp_17q12' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 36(17Q12) MUTATED 17 3 45
AMP PEAK 36(17Q12) WILD-TYPE 350 17 53

Figure S54.  Get High-res Image Gene #36: 'amp_17q12' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_17q25.1' versus 'AGE'

P value = 0.000275 (Wilcoxon-test), Q value = 0.15

Table S55.  Gene #37: 'amp_17q25.1' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 37(17Q25.1) MUTATED 89 67.6 (9.5)
AMP PEAK 37(17Q25.1) WILD-TYPE 395 62.9 (11.5)

Figure S55.  Get High-res Image Gene #37: 'amp_17q25.1' versus Clinical Feature #2: 'AGE'

'amp_17q25.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S56.  Gene #37: 'amp_17q25.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 37(17Q25.1) MUTATED 33 9 47
AMP PEAK 37(17Q25.1) WILD-TYPE 334 11 51

Figure S56.  Get High-res Image Gene #37: 'amp_17q25.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_17q25.1' versus 'RACE'

P value = 3e-05 (Fisher's exact test), Q value = 0.017

Table S57.  Gene #37: 'amp_17q25.1' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 19 73 9 355
AMP PEAK 37(17Q25.1) MUTATED 0 0 28 2 55
AMP PEAK 37(17Q25.1) WILD-TYPE 4 19 45 7 300

Figure S57.  Get High-res Image Gene #37: 'amp_17q25.1' versus Clinical Feature #6: 'RACE'

'amp_18p11.31' versus 'AGE'

P value = 5.28e-05 (Wilcoxon-test), Q value = 0.029

Table S58.  Gene #38: 'amp_18p11.31' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 38(18P11.31) MUTATED 83 67.8 (9.0)
AMP PEAK 38(18P11.31) WILD-TYPE 401 62.9 (11.5)

Figure S58.  Get High-res Image Gene #38: 'amp_18p11.31' versus Clinical Feature #2: 'AGE'

'amp_18p11.31' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S59.  Gene #38: 'amp_18p11.31' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 38(18P11.31) MUTATED 25 6 52
AMP PEAK 38(18P11.31) WILD-TYPE 342 14 46

Figure S59.  Get High-res Image Gene #38: 'amp_18p11.31' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_18q11.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S60.  Gene #39: 'amp_18q11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 39(18Q11.2) MUTATED 18 4 41
AMP PEAK 39(18Q11.2) WILD-TYPE 349 16 57

Figure S60.  Get High-res Image Gene #39: 'amp_18q11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_19p13.2' versus 'AGE'

P value = 3e-10 (Wilcoxon-test), Q value = 2.1e-07

Table S61.  Gene #40: 'amp_19p13.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 40(19P13.2) MUTATED 81 70.5 (8.4)
AMP PEAK 40(19P13.2) WILD-TYPE 403 62.4 (11.3)

Figure S61.  Get High-res Image Gene #40: 'amp_19p13.2' versus Clinical Feature #2: 'AGE'

'amp_19p13.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S62.  Gene #40: 'amp_19p13.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 40(19P13.2) MUTATED 24 8 49
AMP PEAK 40(19P13.2) WILD-TYPE 343 12 49

Figure S62.  Get High-res Image Gene #40: 'amp_19p13.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_19p13.12' versus 'AGE'

P value = 1.22e-10 (Wilcoxon-test), Q value = 8.4e-08

Table S63.  Gene #41: 'amp_19p13.12' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 41(19P13.12) MUTATED 85 70.6 (9.0)
AMP PEAK 41(19P13.12) WILD-TYPE 399 62.3 (11.2)

Figure S63.  Get High-res Image Gene #41: 'amp_19p13.12' versus Clinical Feature #2: 'AGE'

'amp_19p13.12' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S64.  Gene #41: 'amp_19p13.12' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 41(19P13.12) MUTATED 25 7 53
AMP PEAK 41(19P13.12) WILD-TYPE 342 13 45

Figure S64.  Get High-res Image Gene #41: 'amp_19p13.12' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_19p13.12' versus 'RACE'

P value = 0.00046 (Fisher's exact test), Q value = 0.24

Table S65.  Gene #41: 'amp_19p13.12' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 19 73 9 355
AMP PEAK 41(19P13.12) MUTATED 0 0 25 1 52
AMP PEAK 41(19P13.12) WILD-TYPE 4 19 48 8 303

Figure S65.  Get High-res Image Gene #41: 'amp_19p13.12' versus Clinical Feature #6: 'RACE'

'amp_19q12' versus 'Time to Death'

P value = 0.000266 (logrank test), Q value = 0.14

Table S66.  Gene #42: 'amp_19q12' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 483 60 0.0 - 191.8 (22.8)
AMP PEAK 42(19Q12) MUTATED 100 22 0.0 - 125.4 (18.5)
AMP PEAK 42(19Q12) WILD-TYPE 383 38 0.1 - 191.8 (23.5)

Figure S66.  Get High-res Image Gene #42: 'amp_19q12' versus Clinical Feature #1: 'Time to Death'

'amp_19q12' versus 'AGE'

P value = 1.05e-08 (Wilcoxon-test), Q value = 7.2e-06

Table S67.  Gene #42: 'amp_19q12' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 42(19Q12) MUTATED 100 69.0 (8.5)
AMP PEAK 42(19Q12) WILD-TYPE 384 62.4 (11.5)

Figure S67.  Get High-res Image Gene #42: 'amp_19q12' versus Clinical Feature #2: 'AGE'

'amp_19q12' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S68.  Gene #42: 'amp_19q12' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 42(19Q12) MUTATED 22 10 68
AMP PEAK 42(19Q12) WILD-TYPE 345 10 30

Figure S68.  Get High-res Image Gene #42: 'amp_19q12' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_19q12' versus 'RACE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S69.  Gene #42: 'amp_19q12' versus Clinical Feature #6: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER WHITE
ALL 4 19 73 9 355
AMP PEAK 42(19Q12) MUTATED 1 2 33 3 56
AMP PEAK 42(19Q12) WILD-TYPE 3 17 40 6 299

Figure S69.  Get High-res Image Gene #42: 'amp_19q12' versus Clinical Feature #6: 'RACE'

'amp_20p13' versus 'AGE'

P value = 1.13e-06 (Wilcoxon-test), Q value = 0.00075

Table S70.  Gene #43: 'amp_20p13' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 43(20P13) MUTATED 103 68.0 (11.2)
AMP PEAK 43(20P13) WILD-TYPE 381 62.6 (11.0)

Figure S70.  Get High-res Image Gene #43: 'amp_20p13' versus Clinical Feature #2: 'AGE'

'amp_20p13' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S71.  Gene #43: 'amp_20p13' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 43(20P13) MUTATED 48 5 50
AMP PEAK 43(20P13) WILD-TYPE 319 15 48

Figure S71.  Get High-res Image Gene #43: 'amp_20p13' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_20q11.21' versus 'AGE'

P value = 3.71e-08 (Wilcoxon-test), Q value = 2.5e-05

Table S72.  Gene #44: 'amp_20q11.21' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 44(20Q11.21) MUTATED 127 68.1 (9.7)
AMP PEAK 44(20Q11.21) WILD-TYPE 357 62.2 (11.4)

Figure S72.  Get High-res Image Gene #44: 'amp_20q11.21' versus Clinical Feature #2: 'AGE'

'amp_20q11.21' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S73.  Gene #44: 'amp_20q11.21' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 44(20Q11.21) MUTATED 52 6 69
AMP PEAK 44(20Q11.21) WILD-TYPE 315 14 29

Figure S73.  Get High-res Image Gene #44: 'amp_20q11.21' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_20q13.12' versus 'AGE'

P value = 2.22e-08 (Wilcoxon-test), Q value = 1.5e-05

Table S74.  Gene #45: 'amp_20q13.12' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 45(20Q13.12) MUTATED 131 68.3 (10.1)
AMP PEAK 45(20Q13.12) WILD-TYPE 353 62.1 (11.2)

Figure S74.  Get High-res Image Gene #45: 'amp_20q13.12' versus Clinical Feature #2: 'AGE'

'amp_20q13.12' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S75.  Gene #45: 'amp_20q13.12' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 45(20Q13.12) MUTATED 56 7 68
AMP PEAK 45(20Q13.12) WILD-TYPE 311 13 30

Figure S75.  Get High-res Image Gene #45: 'amp_20q13.12' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_20q13.33' versus 'AGE'

P value = 7.28e-08 (Wilcoxon-test), Q value = 4.9e-05

Table S76.  Gene #46: 'amp_20q13.33' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 46(20Q13.33) MUTATED 126 68.1 (10.3)
AMP PEAK 46(20Q13.33) WILD-TYPE 358 62.2 (11.2)

Figure S76.  Get High-res Image Gene #46: 'amp_20q13.33' versus Clinical Feature #2: 'AGE'

'amp_20q13.33' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S77.  Gene #46: 'amp_20q13.33' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 46(20Q13.33) MUTATED 58 6 62
AMP PEAK 46(20Q13.33) WILD-TYPE 309 14 36

Figure S77.  Get High-res Image Gene #46: 'amp_20q13.33' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'amp_22q12.2' versus 'AGE'

P value = 0.000405 (Wilcoxon-test), Q value = 0.21

Table S78.  Gene #47: 'amp_22q12.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
AMP PEAK 47(22Q12.2) MUTATED 53 68.4 (10.4)
AMP PEAK 47(22Q12.2) WILD-TYPE 431 63.2 (11.3)

Figure S78.  Get High-res Image Gene #47: 'amp_22q12.2' versus Clinical Feature #2: 'AGE'

'amp_22q12.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S79.  Gene #47: 'amp_22q12.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
AMP PEAK 47(22Q12.2) MUTATED 11 2 41
AMP PEAK 47(22Q12.2) WILD-TYPE 356 18 57

Figure S79.  Get High-res Image Gene #47: 'amp_22q12.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_1p36.21' versus 'AGE'

P value = 7.06e-05 (Wilcoxon-test), Q value = 0.039

Table S80.  Gene #50: 'del_1p36.21' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 1(1P36.21) MUTATED 60 69.5 (10.4)
DEL PEAK 1(1P36.21) WILD-TYPE 424 62.9 (11.2)

Figure S80.  Get High-res Image Gene #50: 'del_1p36.21' versus Clinical Feature #2: 'AGE'

'del_1p36.21' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S81.  Gene #50: 'del_1p36.21' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 1(1P36.21) MUTATED 24 5 31
DEL PEAK 1(1P36.21) WILD-TYPE 343 15 67

Figure S81.  Get High-res Image Gene #50: 'del_1p36.21' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_1p36.11' versus 'AGE'

P value = 1.57e-05 (Wilcoxon-test), Q value = 0.009

Table S82.  Gene #51: 'del_1p36.11' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 2(1P36.11) MUTATED 72 69.1 (9.6)
DEL PEAK 2(1P36.11) WILD-TYPE 412 62.8 (11.3)

Figure S82.  Get High-res Image Gene #51: 'del_1p36.11' versus Clinical Feature #2: 'AGE'

'del_1p36.11' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S83.  Gene #51: 'del_1p36.11' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 2(1P36.11) MUTATED 24 5 43
DEL PEAK 2(1P36.11) WILD-TYPE 343 15 55

Figure S83.  Get High-res Image Gene #51: 'del_1p36.11' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_2q22.1' versus 'Time to Death'

P value = 6.89e-09 (logrank test), Q value = 4.7e-06

Table S84.  Gene #53: 'del_2q22.1' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 483 60 0.0 - 191.8 (22.8)
DEL PEAK 4(2Q22.1) MUTATED 43 15 0.5 - 125.4 (11.1)
DEL PEAK 4(2Q22.1) WILD-TYPE 440 45 0.0 - 191.8 (23.8)

Figure S84.  Get High-res Image Gene #53: 'del_2q22.1' versus Clinical Feature #1: 'Time to Death'

'del_2q22.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S85.  Gene #53: 'del_2q22.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 4(2Q22.1) MUTATED 16 2 25
DEL PEAK 4(2Q22.1) WILD-TYPE 351 18 73

Figure S85.  Get High-res Image Gene #53: 'del_2q22.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_2q37.3' versus 'HISTOLOGICAL.TYPE'

P value = 0.00044 (Fisher's exact test), Q value = 0.23

Table S86.  Gene #54: 'del_2q37.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 5(2Q37.3) MUTATED 25 2 20
DEL PEAK 5(2Q37.3) WILD-TYPE 342 18 78

Figure S86.  Get High-res Image Gene #54: 'del_2q37.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_3p14.2' versus 'AGE'

P value = 0.000404 (Wilcoxon-test), Q value = 0.21

Table S87.  Gene #55: 'del_3p14.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 6(3P14.2) MUTATED 67 67.9 (8.3)
DEL PEAK 6(3P14.2) WILD-TYPE 417 63.1 (11.5)

Figure S87.  Get High-res Image Gene #55: 'del_3p14.2' versus Clinical Feature #2: 'AGE'

'del_3p14.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S88.  Gene #55: 'del_3p14.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 6(3P14.2) MUTATED 22 6 39
DEL PEAK 6(3P14.2) WILD-TYPE 345 14 59

Figure S88.  Get High-res Image Gene #55: 'del_3p14.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_3q13.31' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S89.  Gene #56: 'del_3q13.31' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 7(3Q13.31) MUTATED 9 3 16
DEL PEAK 7(3Q13.31) WILD-TYPE 358 17 82

Figure S89.  Get High-res Image Gene #56: 'del_3q13.31' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_4p16.3' versus 'AGE'

P value = 0.000115 (Wilcoxon-test), Q value = 0.064

Table S90.  Gene #57: 'del_4p16.3' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 8(4P16.3) MUTATED 78 68.2 (9.1)
DEL PEAK 8(4P16.3) WILD-TYPE 406 62.9 (11.4)

Figure S90.  Get High-res Image Gene #57: 'del_4p16.3' versus Clinical Feature #2: 'AGE'

'del_4p16.3' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S91.  Gene #57: 'del_4p16.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 8(4P16.3) MUTATED 28 5 45
DEL PEAK 8(4P16.3) WILD-TYPE 339 15 53

Figure S91.  Get High-res Image Gene #57: 'del_4p16.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_4p15.31' versus 'AGE'

P value = 5.77e-05 (Wilcoxon-test), Q value = 0.032

Table S92.  Gene #58: 'del_4p15.31' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 9(4P15.31) MUTATED 82 68.3 (9.2)
DEL PEAK 9(4P15.31) WILD-TYPE 402 62.8 (11.4)

Figure S92.  Get High-res Image Gene #58: 'del_4p15.31' versus Clinical Feature #2: 'AGE'

'del_4p15.31' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S93.  Gene #58: 'del_4p15.31' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 9(4P15.31) MUTATED 30 5 47
DEL PEAK 9(4P15.31) WILD-TYPE 337 15 51

Figure S93.  Get High-res Image Gene #58: 'del_4p15.31' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_4q22.1' versus 'AGE'

P value = 9.98e-06 (Wilcoxon-test), Q value = 0.0066

Table S94.  Gene #59: 'del_4q22.1' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 10(4Q22.1) MUTATED 90 68.3 (9.1)
DEL PEAK 10(4Q22.1) WILD-TYPE 394 62.7 (11.5)

Figure S94.  Get High-res Image Gene #59: 'del_4q22.1' versus Clinical Feature #2: 'AGE'

'del_4q22.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S95.  Gene #59: 'del_4q22.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 10(4Q22.1) MUTATED 26 6 58
DEL PEAK 10(4Q22.1) WILD-TYPE 341 14 40

Figure S95.  Get High-res Image Gene #59: 'del_4q22.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_4q34.3' versus 'AGE'

P value = 5.9e-07 (Wilcoxon-test), Q value = 4e-04

Table S96.  Gene #60: 'del_4q34.3' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 11(4Q34.3) MUTATED 113 68.0 (9.9)
DEL PEAK 11(4Q34.3) WILD-TYPE 371 62.4 (11.3)

Figure S96.  Get High-res Image Gene #60: 'del_4q34.3' versus Clinical Feature #2: 'AGE'

'del_4q34.3' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S97.  Gene #60: 'del_4q34.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 11(4Q34.3) MUTATED 38 8 67
DEL PEAK 11(4Q34.3) WILD-TYPE 329 12 31

Figure S97.  Get High-res Image Gene #60: 'del_4q34.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_5q11.2' versus 'AGE'

P value = 5.64e-06 (Wilcoxon-test), Q value = 0.0037

Table S98.  Gene #61: 'del_5q11.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 12(5Q11.2) MUTATED 97 67.9 (9.8)
DEL PEAK 12(5Q11.2) WILD-TYPE 387 62.7 (11.4)

Figure S98.  Get High-res Image Gene #61: 'del_5q11.2' versus Clinical Feature #2: 'AGE'

'del_5q11.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S99.  Gene #61: 'del_5q11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 12(5Q11.2) MUTATED 32 4 61
DEL PEAK 12(5Q11.2) WILD-TYPE 335 16 37

Figure S99.  Get High-res Image Gene #61: 'del_5q11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_6q26' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S100.  Gene #62: 'del_6q26' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 13(6Q26) MUTATED 12 3 26
DEL PEAK 13(6Q26) WILD-TYPE 355 17 72

Figure S100.  Get High-res Image Gene #62: 'del_6q26' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_7p22.3' versus 'Time to Death'

P value = 0.000273 (logrank test), Q value = 0.15

Table S101.  Gene #63: 'del_7p22.3' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 483 60 0.0 - 191.8 (22.8)
DEL PEAK 14(7P22.3) MUTATED 63 16 0.0 - 97.7 (20.0)
DEL PEAK 14(7P22.3) WILD-TYPE 420 44 0.1 - 191.8 (23.3)

Figure S101.  Get High-res Image Gene #63: 'del_7p22.3' versus Clinical Feature #1: 'Time to Death'

'del_7p22.3' versus 'AGE'

P value = 3.29e-05 (Wilcoxon-test), Q value = 0.019

Table S102.  Gene #63: 'del_7p22.3' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 14(7P22.3) MUTATED 63 68.9 (10.1)
DEL PEAK 14(7P22.3) WILD-TYPE 421 63.0 (11.2)

Figure S102.  Get High-res Image Gene #63: 'del_7p22.3' versus Clinical Feature #2: 'AGE'

'del_7p22.3' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S103.  Gene #63: 'del_7p22.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 14(7P22.3) MUTATED 21 5 38
DEL PEAK 14(7P22.3) WILD-TYPE 346 15 60

Figure S103.  Get High-res Image Gene #63: 'del_7p22.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_7q11.22' versus 'AGE'

P value = 1.17e-05 (Wilcoxon-test), Q value = 0.0067

Table S104.  Gene #64: 'del_7q11.22' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 15(7Q11.22) MUTATED 38 71.0 (9.6)
DEL PEAK 15(7Q11.22) WILD-TYPE 446 63.1 (11.2)

Figure S104.  Get High-res Image Gene #64: 'del_7q11.22' versus Clinical Feature #2: 'AGE'

'del_7q11.22' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S105.  Gene #64: 'del_7q11.22' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 15(7Q11.22) MUTATED 13 2 23
DEL PEAK 15(7Q11.22) WILD-TYPE 354 18 75

Figure S105.  Get High-res Image Gene #64: 'del_7q11.22' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_7q31.1' versus 'AGE'

P value = 1.44e-05 (Wilcoxon-test), Q value = 0.0082

Table S106.  Gene #65: 'del_7q31.1' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 16(7Q31.1) MUTATED 48 70.0 (7.8)
DEL PEAK 16(7Q31.1) WILD-TYPE 436 63.1 (11.4)

Figure S106.  Get High-res Image Gene #65: 'del_7q31.1' versus Clinical Feature #2: 'AGE'

'del_7q31.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S107.  Gene #65: 'del_7q31.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 16(7Q31.1) MUTATED 9 3 36
DEL PEAK 16(7Q31.1) WILD-TYPE 358 17 62

Figure S107.  Get High-res Image Gene #65: 'del_7q31.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_7q36.1' versus 'AGE'

P value = 2.61e-08 (Wilcoxon-test), Q value = 1.8e-05

Table S108.  Gene #66: 'del_7q36.1' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 17(7Q36.1) MUTATED 58 71.2 (8.4)
DEL PEAK 17(7Q36.1) WILD-TYPE 426 62.7 (11.2)

Figure S108.  Get High-res Image Gene #66: 'del_7q36.1' versus Clinical Feature #2: 'AGE'

'del_7q36.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S109.  Gene #66: 'del_7q36.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 17(7Q36.1) MUTATED 12 4 42
DEL PEAK 17(7Q36.1) WILD-TYPE 355 16 56

Figure S109.  Get High-res Image Gene #66: 'del_7q36.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_8p23.2' versus 'AGE'

P value = 3.15e-05 (Wilcoxon-test), Q value = 0.018

Table S110.  Gene #67: 'del_8p23.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 18(8P23.2) MUTATED 100 67.4 (9.3)
DEL PEAK 18(8P23.2) WILD-TYPE 384 62.8 (11.6)

Figure S110.  Get High-res Image Gene #67: 'del_8p23.2' versus Clinical Feature #2: 'AGE'

'del_8p23.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S111.  Gene #67: 'del_8p23.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 18(8P23.2) MUTATED 30 5 66
DEL PEAK 18(8P23.2) WILD-TYPE 337 15 32

Figure S111.  Get High-res Image Gene #67: 'del_8p23.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_8p21.2' versus 'AGE'

P value = 3.63e-06 (Wilcoxon-test), Q value = 0.0024

Table S112.  Gene #68: 'del_8p21.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 19(8P21.2) MUTATED 99 68.0 (9.1)
DEL PEAK 19(8P21.2) WILD-TYPE 385 62.6 (11.5)

Figure S112.  Get High-res Image Gene #68: 'del_8p21.2' versus Clinical Feature #2: 'AGE'

'del_8p21.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S113.  Gene #68: 'del_8p21.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 19(8P21.2) MUTATED 22 6 71
DEL PEAK 19(8P21.2) WILD-TYPE 345 14 27

Figure S113.  Get High-res Image Gene #68: 'del_8p21.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_9p23' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S114.  Gene #69: 'del_9p23' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 20(9P23) MUTATED 23 4 37
DEL PEAK 20(9P23) WILD-TYPE 344 16 61

Figure S114.  Get High-res Image Gene #69: 'del_9p23' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_9q21.2' versus 'Time to Death'

P value = 0.000466 (logrank test), Q value = 0.24

Table S115.  Gene #70: 'del_9q21.2' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 483 60 0.0 - 191.8 (22.8)
DEL PEAK 21(9Q21.2) MUTATED 110 23 0.1 - 125.4 (18.1)
DEL PEAK 21(9Q21.2) WILD-TYPE 373 37 0.0 - 191.8 (23.7)

Figure S115.  Get High-res Image Gene #70: 'del_9q21.2' versus Clinical Feature #1: 'Time to Death'

'del_9q21.2' versus 'AGE'

P value = 1.16e-10 (Wilcoxon-test), Q value = 8e-08

Table S116.  Gene #70: 'del_9q21.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 21(9Q21.2) MUTATED 111 69.5 (9.0)
DEL PEAK 21(9Q21.2) WILD-TYPE 373 62.0 (11.3)

Figure S116.  Get High-res Image Gene #70: 'del_9q21.2' versus Clinical Feature #2: 'AGE'

'del_9q21.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S117.  Gene #70: 'del_9q21.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 21(9Q21.2) MUTATED 43 10 58
DEL PEAK 21(9Q21.2) WILD-TYPE 324 10 40

Figure S117.  Get High-res Image Gene #70: 'del_9q21.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_9q34.2' versus 'AGE'

P value = 5.57e-09 (Wilcoxon-test), Q value = 3.8e-06

Table S118.  Gene #71: 'del_9q34.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 22(9Q34.2) MUTATED 114 68.8 (8.6)
DEL PEAK 22(9Q34.2) WILD-TYPE 370 62.2 (11.5)

Figure S118.  Get High-res Image Gene #71: 'del_9q34.2' versus Clinical Feature #2: 'AGE'

'del_9q34.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S119.  Gene #71: 'del_9q34.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 22(9Q34.2) MUTATED 46 10 58
DEL PEAK 22(9Q34.2) WILD-TYPE 321 10 40

Figure S119.  Get High-res Image Gene #71: 'del_9q34.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_10q23.31' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S120.  Gene #72: 'del_10q23.31' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 23(10Q23.31) MUTATED 28 5 33
DEL PEAK 23(10Q23.31) WILD-TYPE 339 15 65

Figure S120.  Get High-res Image Gene #72: 'del_10q23.31' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_11p15.5' versus 'AGE'

P value = 4.25e-06 (Wilcoxon-test), Q value = 0.0028

Table S121.  Gene #73: 'del_11p15.5' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 24(11P15.5) MUTATED 87 68.5 (9.1)
DEL PEAK 24(11P15.5) WILD-TYPE 397 62.7 (11.5)

Figure S121.  Get High-res Image Gene #73: 'del_11p15.5' versus Clinical Feature #2: 'AGE'

'del_11p15.5' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S122.  Gene #73: 'del_11p15.5' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 24(11P15.5) MUTATED 31 5 51
DEL PEAK 24(11P15.5) WILD-TYPE 336 15 47

Figure S122.  Get High-res Image Gene #73: 'del_11p15.5' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_11q14.1' versus 'AGE'

P value = 0.000246 (Wilcoxon-test), Q value = 0.13

Table S123.  Gene #74: 'del_11q14.1' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 25(11Q14.1) MUTATED 59 68.8 (8.9)
DEL PEAK 25(11Q14.1) WILD-TYPE 425 63.0 (11.4)

Figure S123.  Get High-res Image Gene #74: 'del_11q14.1' versus Clinical Feature #2: 'AGE'

'del_11q14.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S124.  Gene #74: 'del_11q14.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 25(11Q14.1) MUTATED 17 6 36
DEL PEAK 25(11Q14.1) WILD-TYPE 350 14 62

Figure S124.  Get High-res Image Gene #74: 'del_11q14.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_11q25' versus 'AGE'

P value = 0.000188 (Wilcoxon-test), Q value = 0.1

Table S125.  Gene #75: 'del_11q25' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 26(11Q25) MUTATED 82 67.7 (10.1)
DEL PEAK 26(11Q25) WILD-TYPE 402 62.9 (11.3)

Figure S125.  Get High-res Image Gene #75: 'del_11q25' versus Clinical Feature #2: 'AGE'

'del_11q25' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S126.  Gene #75: 'del_11q25' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 26(11Q25) MUTATED 29 6 47
DEL PEAK 26(11Q25) WILD-TYPE 338 14 51

Figure S126.  Get High-res Image Gene #75: 'del_11q25' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_12q23.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S127.  Gene #76: 'del_12q23.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 27(12Q23.1) MUTATED 11 3 31
DEL PEAK 27(12Q23.1) WILD-TYPE 356 17 67

Figure S127.  Get High-res Image Gene #76: 'del_12q23.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_12q24.33' versus 'AGE'

P value = 0.000125 (Wilcoxon-test), Q value = 0.069

Table S128.  Gene #77: 'del_12q24.33' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 28(12Q24.33) MUTATED 54 69.0 (9.0)
DEL PEAK 28(12Q24.33) WILD-TYPE 430 63.1 (11.4)

Figure S128.  Get High-res Image Gene #77: 'del_12q24.33' versus Clinical Feature #2: 'AGE'

'del_12q24.33' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S129.  Gene #77: 'del_12q24.33' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 28(12Q24.33) MUTATED 15 2 37
DEL PEAK 28(12Q24.33) WILD-TYPE 352 18 61

Figure S129.  Get High-res Image Gene #77: 'del_12q24.33' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_13q11' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S130.  Gene #78: 'del_13q11' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 29(13Q11) MUTATED 34 5 42
DEL PEAK 29(13Q11) WILD-TYPE 333 15 56

Figure S130.  Get High-res Image Gene #78: 'del_13q11' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_13q14.2' versus 'AGE'

P value = 0.00031 (Wilcoxon-test), Q value = 0.17

Table S131.  Gene #79: 'del_13q14.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 30(13Q14.2) MUTATED 86 67.6 (9.9)
DEL PEAK 30(13Q14.2) WILD-TYPE 398 62.9 (11.4)

Figure S131.  Get High-res Image Gene #79: 'del_13q14.2' versus Clinical Feature #2: 'AGE'

'del_13q14.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S132.  Gene #79: 'del_13q14.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 30(13Q14.2) MUTATED 44 6 36
DEL PEAK 30(13Q14.2) WILD-TYPE 323 14 62

Figure S132.  Get High-res Image Gene #79: 'del_13q14.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_14q13.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S133.  Gene #80: 'del_14q13.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 31(14Q13.1) MUTATED 23 5 34
DEL PEAK 31(14Q13.1) WILD-TYPE 344 15 64

Figure S133.  Get High-res Image Gene #80: 'del_14q13.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_15q15.1' versus 'AGE'

P value = 1.29e-08 (Wilcoxon-test), Q value = 8.8e-06

Table S134.  Gene #81: 'del_15q15.1' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 32(15Q15.1) MUTATED 121 68.5 (9.7)
DEL PEAK 32(15Q15.1) WILD-TYPE 363 62.2 (11.3)

Figure S134.  Get High-res Image Gene #81: 'del_15q15.1' versus Clinical Feature #2: 'AGE'

'del_15q15.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S135.  Gene #81: 'del_15q15.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 32(15Q15.1) MUTATED 47 9 65
DEL PEAK 32(15Q15.1) WILD-TYPE 320 11 33

Figure S135.  Get High-res Image Gene #81: 'del_15q15.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_15q23' versus 'AGE'

P value = 3.29e-06 (Wilcoxon-test), Q value = 0.0022

Table S136.  Gene #82: 'del_15q23' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 33(15Q23) MUTATED 101 67.9 (9.6)
DEL PEAK 33(15Q23) WILD-TYPE 383 62.6 (11.4)

Figure S136.  Get High-res Image Gene #82: 'del_15q23' versus Clinical Feature #2: 'AGE'

'del_15q23' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S137.  Gene #82: 'del_15q23' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 33(15Q23) MUTATED 35 7 59
DEL PEAK 33(15Q23) WILD-TYPE 332 13 39

Figure S137.  Get High-res Image Gene #82: 'del_15q23' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_16p13.3' versus 'AGE'

P value = 2.45e-07 (Wilcoxon-test), Q value = 0.00017

Table S138.  Gene #83: 'del_16p13.3' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 34(16P13.3) MUTATED 78 69.4 (8.7)
DEL PEAK 34(16P13.3) WILD-TYPE 406 62.7 (11.4)

Figure S138.  Get High-res Image Gene #83: 'del_16p13.3' versus Clinical Feature #2: 'AGE'

'del_16p13.3' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S139.  Gene #83: 'del_16p13.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 34(16P13.3) MUTATED 23 5 50
DEL PEAK 34(16P13.3) WILD-TYPE 344 15 48

Figure S139.  Get High-res Image Gene #83: 'del_16p13.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_16q21' versus 'AGE'

P value = 4.58e-09 (Wilcoxon-test), Q value = 3.2e-06

Table S140.  Gene #84: 'del_16q21' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 35(16Q21) MUTATED 135 68.2 (9.3)
DEL PEAK 35(16Q21) WILD-TYPE 349 62.0 (11.5)

Figure S140.  Get High-res Image Gene #84: 'del_16q21' versus Clinical Feature #2: 'AGE'

'del_16q21' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S141.  Gene #84: 'del_16q21' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 35(16Q21) MUTATED 57 8 70
DEL PEAK 35(16Q21) WILD-TYPE 310 12 28

Figure S141.  Get High-res Image Gene #84: 'del_16q21' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_16q23.1' versus 'AGE'

P value = 1.87e-08 (Wilcoxon-test), Q value = 1.3e-05

Table S142.  Gene #85: 'del_16q23.1' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 36(16Q23.1) MUTATED 144 67.7 (9.5)
DEL PEAK 36(16Q23.1) WILD-TYPE 340 62.1 (11.6)

Figure S142.  Get High-res Image Gene #85: 'del_16q23.1' versus Clinical Feature #2: 'AGE'

'del_16q23.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S143.  Gene #85: 'del_16q23.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 36(16Q23.1) MUTATED 62 7 75
DEL PEAK 36(16Q23.1) WILD-TYPE 305 13 23

Figure S143.  Get High-res Image Gene #85: 'del_16q23.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_17p13.3' versus 'Time to Death'

P value = 0.000403 (logrank test), Q value = 0.21

Table S144.  Gene #86: 'del_17p13.3' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 483 60 0.0 - 191.8 (22.8)
DEL PEAK 37(17P13.3) MUTATED 101 21 0.0 - 125.4 (17.8)
DEL PEAK 37(17P13.3) WILD-TYPE 382 39 0.1 - 191.8 (24.3)

Figure S144.  Get High-res Image Gene #86: 'del_17p13.3' versus Clinical Feature #1: 'Time to Death'

'del_17p13.3' versus 'AGE'

P value = 9.52e-05 (Wilcoxon-test), Q value = 0.053

Table S145.  Gene #86: 'del_17p13.3' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 37(17P13.3) MUTATED 102 67.2 (9.3)
DEL PEAK 37(17P13.3) WILD-TYPE 382 62.8 (11.6)

Figure S145.  Get High-res Image Gene #86: 'del_17p13.3' versus Clinical Feature #2: 'AGE'

'del_17p13.3' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S146.  Gene #86: 'del_17p13.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 37(17P13.3) MUTATED 38 9 55
DEL PEAK 37(17P13.3) WILD-TYPE 329 11 43

Figure S146.  Get High-res Image Gene #86: 'del_17p13.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_17p11.2' versus 'AGE'

P value = 7.22e-07 (Wilcoxon-test), Q value = 0.00048

Table S147.  Gene #87: 'del_17p11.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 38(17P11.2) MUTATED 108 68.1 (9.5)
DEL PEAK 38(17P11.2) WILD-TYPE 376 62.5 (11.4)

Figure S147.  Get High-res Image Gene #87: 'del_17p11.2' versus Clinical Feature #2: 'AGE'

'del_17p11.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S148.  Gene #87: 'del_17p11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 38(17P11.2) MUTATED 38 8 62
DEL PEAK 38(17P11.2) WILD-TYPE 329 12 36

Figure S148.  Get High-res Image Gene #87: 'del_17p11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_17p11.2' versus 'AGE'

P value = 1.94e-06 (Wilcoxon-test), Q value = 0.0013

Table S149.  Gene #88: 'del_17p11.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 39(17P11.2) MUTATED 102 68.0 (9.4)
DEL PEAK 39(17P11.2) WILD-TYPE 382 62.6 (11.5)

Figure S149.  Get High-res Image Gene #88: 'del_17p11.2' versus Clinical Feature #2: 'AGE'

'del_17p11.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S150.  Gene #88: 'del_17p11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 39(17P11.2) MUTATED 40 7 55
DEL PEAK 39(17P11.2) WILD-TYPE 327 13 43

Figure S150.  Get High-res Image Gene #88: 'del_17p11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_17q11.2' versus 'AGE'

P value = 5.35e-07 (Wilcoxon-test), Q value = 0.00036

Table S151.  Gene #89: 'del_17q11.2' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 40(17Q11.2) MUTATED 90 68.4 (9.5)
DEL PEAK 40(17Q11.2) WILD-TYPE 394 62.7 (11.4)

Figure S151.  Get High-res Image Gene #89: 'del_17q11.2' versus Clinical Feature #2: 'AGE'

'del_17q11.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S152.  Gene #89: 'del_17q11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 40(17Q11.2) MUTATED 40 5 45
DEL PEAK 40(17Q11.2) WILD-TYPE 327 15 53

Figure S152.  Get High-res Image Gene #89: 'del_17q11.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_17q21.31' versus 'AGE'

P value = 1.95e-05 (Wilcoxon-test), Q value = 0.011

Table S153.  Gene #90: 'del_17q21.31' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 41(17Q21.31) MUTATED 89 67.9 (9.9)
DEL PEAK 41(17Q21.31) WILD-TYPE 395 62.8 (11.4)

Figure S153.  Get High-res Image Gene #90: 'del_17q21.31' versus Clinical Feature #2: 'AGE'

'del_17q21.31' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S154.  Gene #90: 'del_17q21.31' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 41(17Q21.31) MUTATED 38 5 46
DEL PEAK 41(17Q21.31) WILD-TYPE 329 15 52

Figure S154.  Get High-res Image Gene #90: 'del_17q21.31' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_18q21.2' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S155.  Gene #91: 'del_18q21.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 42(18Q21.2) MUTATED 32 6 39
DEL PEAK 42(18Q21.2) WILD-TYPE 335 14 59

Figure S155.  Get High-res Image Gene #91: 'del_18q21.2' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_18q23' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S156.  Gene #92: 'del_18q23' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 43(18Q23) MUTATED 31 6 46
DEL PEAK 43(18Q23) WILD-TYPE 336 14 52

Figure S156.  Get High-res Image Gene #92: 'del_18q23' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_19p13.3' versus 'Time to Death'

P value = 4.5e-06 (logrank test), Q value = 0.003

Table S157.  Gene #93: 'del_19p13.3' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 483 60 0.0 - 191.8 (22.8)
DEL PEAK 44(19P13.3) MUTATED 132 30 0.0 - 125.4 (19.1)
DEL PEAK 44(19P13.3) WILD-TYPE 351 30 0.1 - 191.8 (23.9)

Figure S157.  Get High-res Image Gene #93: 'del_19p13.3' versus Clinical Feature #1: 'Time to Death'

'del_19p13.3' versus 'AGE'

P value = 2.12e-11 (Wilcoxon-test), Q value = 1.5e-08

Table S158.  Gene #93: 'del_19p13.3' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 44(19P13.3) MUTATED 133 68.9 (8.7)
DEL PEAK 44(19P13.3) WILD-TYPE 351 61.8 (11.5)

Figure S158.  Get High-res Image Gene #93: 'del_19p13.3' versus Clinical Feature #2: 'AGE'

'del_19p13.3' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S159.  Gene #93: 'del_19p13.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 44(19P13.3) MUTATED 38 8 87
DEL PEAK 44(19P13.3) WILD-TYPE 329 12 11

Figure S159.  Get High-res Image Gene #93: 'del_19p13.3' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_19p12' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S160.  Gene #94: 'del_19p12' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 45(19P12) MUTATED 16 5 26
DEL PEAK 45(19P12) WILD-TYPE 351 15 72

Figure S160.  Get High-res Image Gene #94: 'del_19p12' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_19q13.43' versus 'Time to Death'

P value = 0.000453 (logrank test), Q value = 0.24

Table S161.  Gene #95: 'del_19q13.43' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 483 60 0.0 - 191.8 (22.8)
DEL PEAK 46(19Q13.43) MUTATED 55 15 0.0 - 125.4 (20.0)
DEL PEAK 46(19Q13.43) WILD-TYPE 428 45 0.1 - 191.8 (23.1)

Figure S161.  Get High-res Image Gene #95: 'del_19q13.43' versus Clinical Feature #1: 'Time to Death'

'del_19q13.43' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S162.  Gene #95: 'del_19q13.43' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 46(19Q13.43) MUTATED 14 4 38
DEL PEAK 46(19Q13.43) WILD-TYPE 353 16 60

Figure S162.  Get High-res Image Gene #95: 'del_19q13.43' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_20p12.1' versus 'Time to Death'

P value = 4.43e-05 (logrank test), Q value = 0.025

Table S163.  Gene #96: 'del_20p12.1' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 483 60 0.0 - 191.8 (22.8)
DEL PEAK 47(20P12.1) MUTATED 31 12 0.1 - 149.6 (20.0)
DEL PEAK 47(20P12.1) WILD-TYPE 452 48 0.0 - 191.8 (23.0)

Figure S163.  Get High-res Image Gene #96: 'del_20p12.1' versus Clinical Feature #1: 'Time to Death'

'del_20p12.1' versus 'HISTOLOGICAL.TYPE'

P value = 0.00023 (Fisher's exact test), Q value = 0.12

Table S164.  Gene #96: 'del_20p12.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 47(20P12.1) MUTATED 14 2 15
DEL PEAK 47(20P12.1) WILD-TYPE 353 18 83

Figure S164.  Get High-res Image Gene #96: 'del_20p12.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_22q11.1' versus 'AGE'

P value = 0.000278 (Wilcoxon-test), Q value = 0.15

Table S165.  Gene #97: 'del_22q11.1' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 48(22Q11.1) MUTATED 73 68.0 (8.8)
DEL PEAK 48(22Q11.1) WILD-TYPE 411 63.0 (11.5)

Figure S165.  Get High-res Image Gene #97: 'del_22q11.1' versus Clinical Feature #2: 'AGE'

'del_22q11.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S166.  Gene #97: 'del_22q11.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 48(22Q11.1) MUTATED 39 4 30
DEL PEAK 48(22Q11.1) WILD-TYPE 328 16 68

Figure S166.  Get High-res Image Gene #97: 'del_22q11.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_22q13.31' versus 'AGE'

P value = 1.06e-08 (Wilcoxon-test), Q value = 7.3e-06

Table S167.  Gene #98: 'del_22q13.31' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 49(22Q13.31) MUTATED 118 68.9 (9.3)
DEL PEAK 49(22Q13.31) WILD-TYPE 366 62.1 (11.4)

Figure S167.  Get High-res Image Gene #98: 'del_22q13.31' versus Clinical Feature #2: 'AGE'

'del_22q13.31' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S168.  Gene #98: 'del_22q13.31' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 49(22Q13.31) MUTATED 46 9 63
DEL PEAK 49(22Q13.31) WILD-TYPE 321 11 35

Figure S168.  Get High-res Image Gene #98: 'del_22q13.31' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'del_xp21.1' versus 'Time to Death'

P value = 0.000453 (logrank test), Q value = 0.24

Table S169.  Gene #99: 'del_xp21.1' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 483 60 0.0 - 191.8 (22.8)
DEL PEAK 50(XP21.1) MUTATED 75 18 0.0 - 113.4 (17.9)
DEL PEAK 50(XP21.1) WILD-TYPE 408 42 0.1 - 191.8 (23.4)

Figure S169.  Get High-res Image Gene #99: 'del_xp21.1' versus Clinical Feature #1: 'Time to Death'

'del_xp21.1' versus 'AGE'

P value = 0.000212 (Wilcoxon-test), Q value = 0.12

Table S170.  Gene #99: 'del_xp21.1' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 484 63.7 (11.3)
DEL PEAK 50(XP21.1) MUTATED 75 68.0 (9.5)
DEL PEAK 50(XP21.1) WILD-TYPE 409 63.0 (11.4)

Figure S170.  Get High-res Image Gene #99: 'del_xp21.1' versus Clinical Feature #2: 'AGE'

'del_xp21.1' versus 'HISTOLOGICAL.TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.0066

Table S171.  Gene #99: 'del_xp21.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 367 20 98
DEL PEAK 50(XP21.1) MUTATED 27 3 45
DEL PEAK 50(XP21.1) WILD-TYPE 340 17 53

Figure S171.  Get High-res Image Gene #99: 'del_xp21.1' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

Methods & Data
Input

  • Copy number data file = transformed.cor.cli.txt

  • Clinical data file = UCEC-TP.merged_data.txt

  • Number of patients = 485

  • Number of significantly focal cnvs = 99

  • Number of selected clinical features = 7

  • Exclude genes that fewer than K tumors have mutations, K = 3

Survival analysis

For survival clinical features, the Kaplan-Meier survival curves of tumors with and without gene mutations were plotted and the statistical significance P values were estimated by logrank test (Bland and Altman 2004) using the 'survdiff' function in R

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

References
[1] Bland and Altman, Statistics notes: The logrank test, BMJ 328(7447):1073 (2004)
[2] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)
[3] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)
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