Correlation between gene mutation status and molecular subtypes

Adrenocortical Carcinoma (Primary solid tumor)

15 July 2014 | analyses__2014_07_15

Maintainer Information

Citation Information

Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)

Cite as Broad Institute TCGA Genome Data Analysis Center (2014): Correlation between gene mutation status and molecular subtypes. Broad Institute of MIT and Harvard. doi:10.7908/C1QC026W

Overview

Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 142 genes and 8 molecular subtypes across 64 patients, no significant finding detected with P value < 0.05 and Q value < 0.25.

No gene mutations related to molecuar subtypes.

Results

Overview of the results

Table 1. Get Full Table Overview of the association between mutation status of 142 genes and 8 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, no significant finding detected.


		Clinical Features	CN CNMF	METHLYATION CNMF	MRNASEQ CNMF	MRNASEQ CHIERARCHICAL	MIRSEQ CNMF	MIRSEQ CHIERARCHICAL	MIRSEQ MATURE CNMF	MIRSEQ MATURE CHIERARCHICAL
	nMutated (%)	nWild-Type	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test
ZFPM1	26 (41%)	38	0.181 (1.00)	0.81 (1.00)	0.335 (1.00)	0.819 (1.00)	0.68 (1.00)	0.838 (1.00)	0.492 (1.00)	0.938 (1.00)
LACTB	20 (31%)	44	0.117 (1.00)	0.682 (1.00)	1 (1.00)	0.56 (1.00)	0.454 (1.00)	0.743 (1.00)	0.314 (1.00)	0.756 (1.00)
CCDC102A	17 (27%)	47	0.131 (1.00)	0.936 (1.00)	0.911 (1.00)	0.758 (1.00)	0.439 (1.00)	0.476 (1.00)	0.687 (1.00)	0.145 (1.00)
ZNF517	13 (20%)	51	0.652 (1.00)	0.962 (1.00)	0.884 (1.00)	1 (1.00)	0.236 (1.00)	0.667 (1.00)	0.799 (1.00)	0.427 (1.00)
TOR3A	12 (19%)	52	0.273 (1.00)	0.0221 (1.00)	0.638 (1.00)	0.0151 (1.00)	1 (1.00)	0.868 (1.00)	0.828 (1.00)	0.662 (1.00)
USP42	16 (25%)	48	0.725 (1.00)	0.0487 (1.00)	1 (1.00)	0.96 (1.00)	0.567 (1.00)	0.839 (1.00)	0.748 (1.00)	0.289 (1.00)
CLDN23	10 (16%)	54	0.263 (1.00)	0.247 (1.00)	0.0237 (1.00)	0.181 (1.00)	0.0905 (1.00)	0.19 (1.00)	0.108 (1.00)	0.322 (1.00)
TP53	13 (20%)	51	0.0216 (1.00)	0.775 (1.00)	0.0201 (1.00)	0.666 (1.00)	0.018 (1.00)	0.638 (1.00)	0.0416 (1.00)	0.192 (1.00)
KCNK17	9 (14%)	55	0.103 (1.00)	0.0379 (1.00)	0.0944 (1.00)	0.00996 (1.00)	1 (1.00)	0.522 (1.00)	0.474 (1.00)	0.417 (1.00)
LZTR1	6 (9%)	58	0.224 (1.00)	0.806 (1.00)	0.0894 (1.00)	0.194 (1.00)	0.417 (1.00)	0.0137 (1.00)	0.445 (1.00)	0.0854 (1.00)
APOE	7 (11%)	57	0.17 (1.00)	0.62 (1.00)	0.0669 (1.00)	0.453 (1.00)	0.279 (1.00)	0.822 (1.00)	0.027 (1.00)	0.825 (1.00)
CCDC105	7 (11%)	57	0.169 (1.00)	0.00859 (1.00)	0.881 (1.00)	0.714 (1.00)	1 (1.00)	0.0509 (1.00)	0.859 (1.00)	0.326 (1.00)
RINL	8 (12%)	56	0.146 (1.00)	0.701 (1.00)	0.509 (1.00)	0.294 (1.00)	0.882 (1.00)	0.166 (1.00)	0.438 (1.00)	0.187 (1.00)
MAL2	12 (19%)	52	0.782 (1.00)	0.303 (1.00)	0.199 (1.00)	0.518 (1.00)	0.123 (1.00)	0.277 (1.00)	0.644 (1.00)	0.321 (1.00)
LRIG1	17 (27%)	47	0.654 (1.00)	0.894 (1.00)	1 (1.00)	0.781 (1.00)	0.186 (1.00)	0.496 (1.00)	0.696 (1.00)	0.874 (1.00)
C19ORF10	8 (12%)	56	0.633 (1.00)	0.355 (1.00)	0.235 (1.00)	0.109 (1.00)	0.55 (1.00)	0.86 (1.00)	0.287 (1.00)	0.761 (1.00)
C10ORF95	7 (11%)	57	0.172 (1.00)	0.707 (1.00)	0.557 (1.00)	0.817 (1.00)	0.75 (1.00)	0.491 (1.00)	0.862 (1.00)	0.505 (1.00)
SYT8	9 (14%)	55	0.428 (1.00)	0.403 (1.00)	0.0346 (1.00)	0.147 (1.00)	1 (1.00)	0.216 (1.00)	1 (1.00)	0.643 (1.00)
IDUA	9 (14%)	55	0.545 (1.00)	0.894 (1.00)	0.345 (1.00)	0.54 (1.00)	0.122 (1.00)	0.457 (1.00)	0.196 (1.00)	0.483 (1.00)
HHIPL1	8 (12%)	56	0.126 (1.00)	0.285 (1.00)	0.358 (1.00)	0.204 (1.00)	0.176 (1.00)	0.786 (1.00)	0.289 (1.00)	0.201 (1.00)
ASPDH	8 (12%)	56	0.306 (1.00)	0.644 (1.00)	0.0203 (1.00)	0.344 (1.00)	0.476 (1.00)	0.0277 (1.00)	0.368 (1.00)	0.0793 (1.00)
C1ORF106	9 (14%)	55	0.77 (1.00)	0.434 (1.00)	0.343 (1.00)	0.861 (1.00)	0.478 (1.00)	0.689 (1.00)	0.616 (1.00)	1 (1.00)
THEM4	6 (9%)	58	0.00358 (1.00)	0.734 (1.00)	0.437 (1.00)	0.886 (1.00)	0.245 (1.00)	0.0938 (1.00)	0.25 (1.00)	0.111 (1.00)
CTNNB1	7 (11%)	57	1 (1.00)	0.167 (1.00)	0.0194 (1.00)	0.0181 (1.00)	0.00174 (1.00)	0.169 (1.00)	0.0272 (1.00)	0.48 (1.00)
GDF1	5 (8%)	59	0.396 (1.00)	0.312 (1.00)	0.362 (1.00)	0.254 (1.00)	0.0896 (1.00)	0.54 (1.00)	0.0192 (1.00)	0.713 (1.00)
TSC22D2	8 (12%)	56	0.349 (1.00)	0.528 (1.00)	0.815 (1.00)	0.942 (1.00)	0.883 (1.00)	0.426 (1.00)	1 (1.00)	0.334 (1.00)
ZAR1	11 (17%)	53	0.175 (1.00)	0.667 (1.00)	0.602 (1.00)	0.802 (1.00)	0.72 (1.00)	1 (1.00)	0.52 (1.00)	0.715 (1.00)
RGS9BP	8 (12%)	56	0.295 (1.00)	0.585 (1.00)	1 (1.00)	0.888 (1.00)	0.335 (1.00)	0.962 (1.00)	0.884 (1.00)	0.343 (1.00)
OPRD1	12 (19%)	52	0.824 (1.00)	0.388 (1.00)	0.797 (1.00)	0.961 (1.00)	0.34 (1.00)	0.631 (1.00)	0.469 (1.00)	0.466 (1.00)
C16ORF3	6 (9%)	58	0.904 (1.00)	0.00079 (0.784)	0.799 (1.00)	0.831 (1.00)	0.594 (1.00)	1 (1.00)	0.698 (1.00)	0.711 (1.00)
FPGS	6 (9%)	58	1 (1.00)	1 (1.00)	0.614 (1.00)	0.614 (1.00)	0.0905 (1.00)	0.624 (1.00)	0.675 (1.00)	0.787 (1.00)
PLIN5	5 (8%)	59	0.561 (1.00)	0.693 (1.00)	0.799 (1.00)	0.542 (1.00)	0.35 (1.00)	0.308 (1.00)	0.129 (1.00)	0.321 (1.00)
IRX3	5 (8%)	59	0.333 (1.00)	0.733 (1.00)	0.52 (1.00)	0.193 (1.00)	0.246 (1.00)	0.779 (1.00)	0.25 (1.00)	0.0204 (1.00)
TRIOBP	12 (19%)	52	0.821 (1.00)	0.176 (1.00)	1 (1.00)	0.128 (1.00)	0.902 (1.00)	0.93 (1.00)	0.665 (1.00)	0.746 (1.00)
KRTAP4-5	5 (8%)	59	0.769 (1.00)	0.313 (1.00)	1 (1.00)	0.886 (1.00)	1 (1.00)	0.84 (1.00)	1 (1.00)	0.894 (1.00)
ATXN1	10 (16%)	54	0.408 (1.00)	0.129 (1.00)	0.234 (1.00)	0.627 (1.00)	0.324 (1.00)	0.852 (1.00)	0.41 (1.00)	0.851 (1.00)
ZNF628	7 (11%)	57	0.305 (1.00)	0.892 (1.00)	0.351 (1.00)	0.122 (1.00)	0.125 (1.00)	0.494 (1.00)	0.0953 (1.00)	0.725 (1.00)
WDR34	5 (8%)	59	0.674 (1.00)	0.772 (1.00)	0.931 (1.00)	0.834 (1.00)	0.843 (1.00)	0.523 (1.00)	1 (1.00)	0.396 (1.00)
BTBD11	6 (9%)	58	1 (1.00)	0.235 (1.00)	0.48 (1.00)	1 (1.00)	0.493 (1.00)	0.165 (1.00)	0.491 (1.00)	0.213 (1.00)
GARS	21 (33%)	43	0.236 (1.00)	0.0685 (1.00)	0.433 (1.00)	0.063 (1.00)	0.238 (1.00)	0.339 (1.00)	0.0989 (1.00)	0.342 (1.00)
ZNF598	13 (20%)	51	0.446 (1.00)	0.377 (1.00)	0.534 (1.00)	1 (1.00)	1 (1.00)	0.215 (1.00)	1 (1.00)	0.162 (1.00)
BHLHE22	5 (8%)	59	0.391 (1.00)	0.0641 (1.00)	0.104 (1.00)	0.83 (1.00)	0.595 (1.00)	0.881 (1.00)	0.698 (1.00)	0.785 (1.00)
PTPLA	4 (6%)	60	0.441 (1.00)	0.292 (1.00)	0.332 (1.00)	0.474 (1.00)	0.79 (1.00)	1 (1.00)	0.21 (1.00)	0.583 (1.00)
CD320	4 (6%)	60	0.935 (1.00)	0.897 (1.00)	0.737 (1.00)	0.684 (1.00)	0.416 (1.00)	0.221 (1.00)	0.175 (1.00)	0.173 (1.00)
KIAA1984	4 (6%)	60	0.252 (1.00)	0.735 (1.00)	0.126 (1.00)	0.0463 (1.00)	0.0364 (1.00)	0.58 (1.00)	0.0617 (1.00)	0.669 (1.00)
TPO	12 (19%)	52	0.532 (1.00)	0.305 (1.00)	0.214 (1.00)	0.159 (1.00)	0.14 (1.00)	0.319 (1.00)	0.28 (1.00)	0.122 (1.00)
AATK	6 (9%)	58	0.115 (1.00)	0.316 (1.00)	0.36 (1.00)	0.251 (1.00)	1 (1.00)	0.506 (1.00)	1 (1.00)	0.455 (1.00)
PANK2	5 (8%)	59	0.735 (1.00)	0.428 (1.00)	0.114 (1.00)	0.108 (1.00)	0.441 (1.00)	0.342 (1.00)	0.594 (1.00)	0.323 (1.00)
SNED1	6 (9%)	58	0.394 (1.00)	0.594 (1.00)	0.212 (1.00)	0.455 (1.00)	0.0442 (1.00)	0.649 (1.00)	0.0459 (1.00)	0.321 (1.00)
CCDC150	4 (6%)	60	0.441 (1.00)	0.808 (1.00)	0.265 (1.00)	0.197 (1.00)	0.417 (1.00)	0.182 (1.00)	0.442 (1.00)	0.143 (1.00)
ERCC2	10 (16%)	54	0.756 (1.00)	0.196 (1.00)	0.51 (1.00)	0.149 (1.00)	0.671 (1.00)	0.239 (1.00)	0.29 (1.00)	0.0884 (1.00)
RREB1	5 (8%)	59	0.736 (1.00)	0.807 (1.00)	0.612 (1.00)	1 (1.00)	0.675 (1.00)	0.504 (1.00)	0.675 (1.00)	0.554 (1.00)
RNF39	5 (8%)	59	0.427 (1.00)	0.311 (1.00)	0.184 (1.00)	0.267 (1.00)	0.167 (1.00)	0.695 (1.00)	0.351 (1.00)	0.553 (1.00)
SEMA5B	8 (12%)	56	0.39 (1.00)	0.35 (1.00)	0.399 (1.00)	0.274 (1.00)	0.853 (1.00)	0.337 (1.00)	0.637 (1.00)	0.666 (1.00)
TAF5	4 (6%)	60	0.937 (1.00)	0.733 (1.00)	1 (1.00)	0.884 (1.00)	0.0212 (1.00)	0.121 (1.00)	0.0195 (1.00)	0.197 (1.00)
SARM1	7 (11%)	57	0.0301 (1.00)	0.435 (1.00)	0.275 (1.00)	0.0285 (1.00)	0.113 (1.00)	0.754 (1.00)	0.046 (1.00)	0.917 (1.00)
PRSS27	3 (5%)	61	0.797 (1.00)	0.909 (1.00)	0.609 (1.00)	0.108 (1.00)	0.141 (1.00)	1 (1.00)	0.206 (1.00)	1 (1.00)
TMEM189	4 (6%)	60	0.162 (1.00)
NOXA1	5 (8%)	59	0.15 (1.00)	0.426 (1.00)	0.219 (1.00)	0.476 (1.00)	0.302 (1.00)	0.341 (1.00)	0.314 (1.00)	0.328 (1.00)
LRP11	7 (11%)	57	0.0406 (1.00)	0.0727 (1.00)	0.799 (1.00)	0.541 (1.00)	0.593 (1.00)	0.936 (1.00)	0.695 (1.00)	0.95 (1.00)
RNF149	4 (6%)	60	0.376 (1.00)	0.0356 (1.00)	0.36 (1.00)	0.616 (1.00)	0.329 (1.00)	0.353 (1.00)	0.343 (1.00)	0.444 (1.00)
DMKN	3 (5%)	61	0.801 (1.00)	0.292 (1.00)	0.611 (1.00)	0.474 (1.00)	0.00831 (1.00)	0.56 (1.00)	0.0101 (1.00)	0.823 (1.00)
FANK1	4 (6%)	60	0.936 (1.00)	0.35 (1.00)	0.855 (1.00)	0.328 (1.00)	0.79 (1.00)	0.227 (1.00)	1 (1.00)	0.172 (1.00)
MUC5B	22 (34%)	42	1 (1.00)	0.572 (1.00)	0.676 (1.00)	0.731 (1.00)	0.817 (1.00)	0.631 (1.00)	0.591 (1.00)	0.846 (1.00)
PABPC1	4 (6%)	60	0.415 (1.00)
GLTPD2	6 (9%)	58	0.0714 (1.00)	0.844 (1.00)	0.883 (1.00)	0.453 (1.00)	0.553 (1.00)	0.51 (1.00)	0.858 (1.00)	0.597 (1.00)
MEN1	5 (8%)	59	0.0955 (1.00)	0.0433 (1.00)	0.0127 (1.00)	0.00613 (1.00)	0.215 (1.00)	0.0387 (1.00)	0.351 (1.00)	0.00889 (1.00)
SRPX	3 (5%)	61	0.894 (1.00)	0.125 (1.00)	0.468 (1.00)	1 (1.00)	0.789 (1.00)	0.789 (1.00)	1 (1.00)	0.822 (1.00)
MAP1S	5 (8%)	59	0.276 (1.00)	0.384 (1.00)	0.349 (1.00)	1 (1.00)	1 (1.00)	0.882 (1.00)	0.842 (1.00)	1 (1.00)
SCRT1	3 (5%)	61	0.799 (1.00)	0.425 (1.00)	0.609 (1.00)	0.639 (1.00)	0.441 (1.00)	0.71 (1.00)	0.592 (1.00)	0.875 (1.00)
OBSCN	20 (31%)	44	0.657 (1.00)	0.261 (1.00)	0.458 (1.00)	0.624 (1.00)	0.0945 (1.00)	0.78 (1.00)	0.196 (1.00)	0.73 (1.00)
IER5	3 (5%)	61	0.369 (1.00)
TNIP2	5 (8%)	59	0.673 (1.00)	0.625 (1.00)	0.735 (1.00)	0.887 (1.00)	1 (1.00)	0.402 (1.00)	1 (1.00)	0.235 (1.00)
NOTCH2	7 (11%)	57	0.304 (1.00)	0.798 (1.00)	0.35 (1.00)	0.0338 (1.00)	0.00835 (1.00)	0.417 (1.00)	0.00893 (1.00)	0.325 (1.00)
RASIP1	7 (11%)	57	0.63 (1.00)	0.676 (1.00)	0.0391 (1.00)	0.159 (1.00)	0.022 (1.00)	0.686 (1.00)	0.0377 (1.00)	0.748 (1.00)
NMU	5 (8%)	59	0.821 (1.00)	1 (1.00)	0.0485 (1.00)	0.639 (1.00)	1 (1.00)	0.506 (1.00)	1 (1.00)	0.455 (1.00)
VARS	6 (9%)	58	0.445 (1.00)	0.437 (1.00)	0.185 (1.00)	0.0818 (1.00)	0.854 (1.00)	0.861 (1.00)	0.34 (1.00)	0.762 (1.00)
SHOX2	3 (5%)	61	0.334 (1.00)
HSD17B1	4 (6%)	60	1 (1.00)	0.108 (1.00)	1 (1.00)	0.0127 (1.00)	1 (1.00)	0.84 (1.00)	1 (1.00)	0.762 (1.00)
COQ2	5 (8%)	59	0.296 (1.00)	0.765 (1.00)	0.361 (1.00)	0.616 (1.00)	1 (1.00)	0.669 (1.00)	1 (1.00)	0.762 (1.00)
KNDC1	10 (16%)	54	0.785 (1.00)	0.129 (1.00)	0.141 (1.00)	0.372 (1.00)	0.288 (1.00)	0.357 (1.00)	0.228 (1.00)	0.749 (1.00)
AR	4 (6%)	60	0.32 (1.00)	0.426 (1.00)	0.61 (1.00)	0.472 (1.00)	0.445 (1.00)	1 (1.00)	0.596 (1.00)	1 (1.00)
KCTD3	4 (6%)	60	0.414 (1.00)
FZD1	3 (5%)	61	0.407 (1.00)
ZC3H12D	3 (5%)	61	0.0033 (1.00)
KRTAP5-5	5 (8%)	59	0.362 (1.00)	1 (1.00)	0.219 (1.00)	0.216 (1.00)	0.444 (1.00)	0.18 (1.00)	0.593 (1.00)	0.056 (1.00)
AKAP2	4 (6%)	60	0.0745 (1.00)	0.475 (1.00)	0.738 (1.00)	0.316 (1.00)	0.673 (1.00)	0.468 (1.00)	0.341 (1.00)	0.647 (1.00)
KBTBD13	9 (14%)	55	0.584 (1.00)	0.107 (1.00)	0.734 (1.00)	0.135 (1.00)	1 (1.00)	0.358 (1.00)	1 (1.00)	0.78 (1.00)
SPIRE2	3 (5%)	61	0.302 (1.00)	0.0267 (1.00)	1 (1.00)	0.824 (1.00)	1 (1.00)	0.708 (1.00)	1 (1.00)	0.875 (1.00)
NPTX1	3 (5%)	61	0.337 (1.00)	1 (1.00)	1 (1.00)	0.825 (1.00)	0.587 (1.00)	0.708 (1.00)	0.43 (1.00)	0.657 (1.00)
ADAD2	4 (6%)	60	0.251 (1.00)	0.574 (1.00)	0.738 (1.00)	0.317 (1.00)	0.0206 (1.00)	0.54 (1.00)	0.0196 (1.00)	0.837 (1.00)
SEZ6L2	8 (12%)	56	0.355 (1.00)	0.598 (1.00)	0.882 (1.00)	1 (1.00)	0.459 (1.00)	0.584 (1.00)	0.456 (1.00)	0.808 (1.00)
NEFH	7 (11%)	57	0.0362 (1.00)	0.157 (1.00)	0.0236 (1.00)	0.00825 (1.00)	0.168 (1.00)	0.521 (1.00)	0.35 (1.00)	0.158 (1.00)
DLEU7	3 (5%)	61	0.568 (1.00)
AMDHD1	11 (17%)	53	0.0266 (1.00)	0.721 (1.00)	0.569 (1.00)	0.185 (1.00)	0.236 (1.00)	0.888 (1.00)	0.0625 (1.00)	0.954 (1.00)
GLTSCR2	5 (8%)	59	0.22 (1.00)	0.806 (1.00)	0.264 (1.00)	0.197 (1.00)	1 (1.00)	0.623 (1.00)	0.251 (1.00)	0.589 (1.00)
PLEC	13 (20%)	51	0.612 (1.00)	0.713 (1.00)	0.194 (1.00)	0.681 (1.00)	0.673 (1.00)	0.604 (1.00)	0.396 (1.00)	0.471 (1.00)
MAP7	3 (5%)	61	1 (1.00)	0.697 (1.00)	1 (1.00)	0.825 (1.00)	0.588 (1.00)	0.708 (1.00)	0.429 (1.00)	0.655 (1.00)
DSPP	10 (16%)	54	0.928 (1.00)	0.064 (1.00)	1 (1.00)	0.516 (1.00)	0.515 (1.00)	0.574 (1.00)	0.313 (1.00)	0.33 (1.00)
CRIPAK	10 (16%)	54	0.201 (1.00)	0.928 (1.00)	0.474 (1.00)	0.836 (1.00)	0.807 (1.00)	0.359 (1.00)	0.719 (1.00)	0.287 (1.00)
PRKAR1A	6 (9%)	58	0.487 (1.00)	1 (1.00)	0.277 (1.00)	0.457 (1.00)	0.0865 (1.00)	0.564 (1.00)	0.174 (1.00)	0.151 (1.00)
CYP4A22	4 (6%)	60	0.113 (1.00)	0.622 (1.00)	0.163 (1.00)	0.507 (1.00)	0.246 (1.00)	0.207 (1.00)	0.249 (1.00)	0.837 (1.00)
NOM1	6 (9%)	58	1 (1.00)	0.233 (1.00)	0.93 (1.00)	1 (1.00)	1 (1.00)	0.742 (1.00)	0.84 (1.00)	0.276 (1.00)
RNF135	3 (5%)	61	0.894 (1.00)
C12ORF65	3 (5%)	61	0.371 (1.00)	0.0354 (1.00)	0.113 (1.00)	0.0623 (1.00)	0.445 (1.00)	0.563 (1.00)	0.593 (1.00)	0.735 (1.00)
HLA-B	6 (9%)	58	0.293 (1.00)	0.775 (1.00)	0.883 (1.00)	1 (1.00)	0.653 (1.00)	0.274 (1.00)	0.535 (1.00)	0.319 (1.00)
CSGALNACT2	3 (5%)	61	0.895 (1.00)	0.0256 (1.00)	0.691 (1.00)	0.823 (1.00)	0.584 (1.00)	0.876 (1.00)	0.43 (1.00)	0.933 (1.00)
UQCRFS1	5 (8%)	59	0.508 (1.00)	0.502 (1.00)	1 (1.00)	0.885 (1.00)	0.49 (1.00)	0.187 (1.00)	0.494 (1.00)	0.0508 (1.00)
PDCD6	3 (5%)	61	0.302 (1.00)	0.699 (1.00)			1 (1.00)	0.632 (1.00)	1 (1.00)	0.696 (1.00)
PTX4	3 (5%)	61	0.568 (1.00)	1 (1.00)	0.612 (1.00)	0.217 (1.00)	0.444 (1.00)	1 (1.00)	0.595 (1.00)	0.392 (1.00)
SGK223	3 (5%)	61	0.895 (1.00)
POLRMT	4 (6%)	60	0.508 (1.00)	0.0363 (1.00)	0.327 (1.00)	0.0737 (1.00)	0.189 (1.00)	0.353 (1.00)	0.125 (1.00)	0.443 (1.00)
CACNA1D	3 (5%)	61	0.566 (1.00)
NF1	7 (11%)	57	0.152 (1.00)	0.904 (1.00)	0.41 (1.00)	0.268 (1.00)	0.342 (1.00)	0.853 (1.00)	0.0999 (1.00)	0.527 (1.00)
RGMB	6 (9%)	58	0.581 (1.00)
ADAMTS7	4 (6%)	60	0.14 (1.00)	0.575 (1.00)	0.0732 (1.00)	0.465 (1.00)	0.061 (1.00)	0.351 (1.00)	0.038 (1.00)	0.288 (1.00)
CLIC6	6 (9%)	58	0.962 (1.00)	1 (1.00)	0.665 (1.00)	0.193 (1.00)	0.246 (1.00)	0.579 (1.00)	0.248 (1.00)	0.759 (1.00)
EMR2	4 (6%)	60	0.375 (1.00)	0.314 (1.00)	0.473 (1.00)	0.614 (1.00)	0.674 (1.00)	0.207 (1.00)	0.676 (1.00)	0.839 (1.00)
PCDHB13	5 (8%)	59	0.513 (1.00)	0.139 (1.00)	0.107 (1.00)	0.256 (1.00)	0.542 (1.00)	0.0566 (1.00)	0.801 (1.00)	0.0126 (1.00)
MTFMT	3 (5%)	61	1 (1.00)
SPTAN1	3 (5%)	61	0.244 (1.00)
HLA-A	3 (5%)	61	1 (1.00)	1 (1.00)	0.854 (1.00)	0.219 (1.00)	1 (1.00)	0.445 (1.00)	1 (1.00)	0.215 (1.00)
ASB16	6 (9%)	58	0.743 (1.00)	0.945 (1.00)	0.614 (1.00)	0.885 (1.00)	0.543 (1.00)	0.778 (1.00)	0.802 (1.00)	0.959 (1.00)
GPRIN2	9 (14%)	55	0.591 (1.00)	0.37 (1.00)	0.65 (1.00)	0.428 (1.00)	0.582 (1.00)	0.801 (1.00)	0.381 (1.00)	0.647 (1.00)
HNRNPCL1	3 (5%)	61	0.336 (1.00)
BTNL9	4 (6%)	60	0.416 (1.00)	0.0962 (1.00)	0.141 (1.00)	0.0618 (1.00)	0.142 (1.00)	1 (1.00)	0.209 (1.00)	1 (1.00)
KCNJ11	4 (6%)	60	0.0135 (1.00)	0.624 (1.00)	0.434 (1.00)	0.14 (1.00)	0.132 (1.00)	0.0498 (1.00)	0.174 (1.00)	0.211 (1.00)
JMJD4	3 (5%)	61	0.8 (1.00)
LRRC4B	6 (9%)	58	0.188 (1.00)	0.189 (1.00)	0.0133 (1.00)	0.0708 (1.00)	0.174 (1.00)	0.0299 (1.00)	0.172 (1.00)	0.00974 (1.00)
OPLAH	3 (5%)	61	0.566 (1.00)	0.854 (1.00)	0.608 (1.00)	0.472 (1.00)	0.443 (1.00)	0.342 (1.00)	0.594 (1.00)	0.394 (1.00)
BAGE2	3 (5%)	61	0.895 (1.00)
MADCAM1	3 (5%)	61	0.481 (1.00)	0.696 (1.00)			1 (1.00)	0.199 (1.00)	1 (1.00)	0.136 (1.00)
CTBP2	3 (5%)	61	0.895 (1.00)
MSH3	4 (6%)	60	0.0176 (1.00)	0.7 (1.00)	0.335 (1.00)	1 (1.00)	0.3 (1.00)	0.442 (1.00)	0.314 (1.00)	0.495 (1.00)
ATN1	4 (6%)	60	0.13 (1.00)	0.853 (1.00)	0.855 (1.00)	1 (1.00)	0.791 (1.00)	0.79 (1.00)	1 (1.00)	0.823 (1.00)
FAM46A	3 (5%)	61	0.897 (1.00)
UTS2R	3 (5%)	61	0.162 (1.00)	0.699 (1.00)	0.69 (1.00)	0.824 (1.00)	0.586 (1.00)	0.791 (1.00)	0.428 (1.00)	0.823 (1.00)
SMG1	3 (5%)	61	0.164 (1.00)	0.125 (1.00)	0.143 (1.00)	0.0621 (1.00)	0.305 (1.00)	0.0256 (1.00)	0.316 (1.00)	0.188 (1.00)
FUCA1	3 (5%)	61	0.404 (1.00)
FEZ2	3 (5%)	61	0.477 (1.00)	0.348 (1.00)	0.179 (1.00)	0.825 (1.00)	0.209 (1.00)	0.709 (1.00)	0.133 (1.00)	0.658 (1.00)
GLI3	5 (8%)	59	0.737 (1.00)	0.407 (1.00)	1 (1.00)	0.885 (1.00)	0.134 (1.00)	0.399 (1.00)	0.176 (1.00)	0.0919 (1.00)
NOL9	4 (6%)	60	0.00202 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	0.789 (1.00)	0.559 (1.00)	1 (1.00)	0.733 (1.00)

'ZFPM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S1. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
ZFPM1 MUTATED	10	7	2	6	1
ZFPM1 WILD-TYPE	11	12	6	2	5

'ZFPM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S2. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
ZFPM1 MUTATED	6	4	4	6	2
ZFPM1 WILD-TYPE	7	4	10	8	5

'ZFPM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.335 (Fisher's exact test), Q value = 1

Table S3. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
ZFPM1 MUTATED	8	1	7	6
ZFPM1 WILD-TYPE	9	7	7	10

'ZFPM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S4. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
ZFPM1 MUTATED	8	6	2	6
ZFPM1 WILD-TYPE	8	10	3	12

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.68 (Fisher's exact test), Q value = 1

Table S5. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
ZFPM1 MUTATED	10	6	6
ZFPM1 WILD-TYPE	16	6	12

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S6. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
ZFPM1 MUTATED	5	9	2	5	1
ZFPM1 WILD-TYPE	8	10	6	9	1

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.492 (Fisher's exact test), Q value = 1

Table S7. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
ZFPM1 MUTATED	10	7	5
ZFPM1 WILD-TYPE	17	6	11

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.938 (Fisher's exact test), Q value = 1

Table S8. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
ZFPM1 MUTATED	4	7	2	5	3	1
ZFPM1 WILD-TYPE	5	10	5	7	3	4

'LACTB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.117 (Fisher's exact test), Q value = 1

Table S9. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
LACTB MUTATED	5	5	2	6	2
LACTB WILD-TYPE	16	14	6	2	4

'LACTB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S10. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
LACTB MUTATED	2	3	5	4	3
LACTB WILD-TYPE	11	5	9	10	4

'LACTB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S11. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
LACTB MUTATED	5	2	5	5
LACTB WILD-TYPE	12	6	9	11

'LACTB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.56 (Fisher's exact test), Q value = 1

Table S12. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
LACTB MUTATED	4	5	3	5
LACTB WILD-TYPE	12	11	2	13

'LACTB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S13. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
LACTB MUTATED	6	5	6
LACTB WILD-TYPE	20	7	12

'LACTB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S14. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
LACTB MUTATED	4	5	4	4	0
LACTB WILD-TYPE	9	14	4	10	2

'LACTB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S15. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
LACTB MUTATED	6	6	5
LACTB WILD-TYPE	21	7	11

'LACTB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.756 (Fisher's exact test), Q value = 1

Table S16. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
LACTB MUTATED	3	4	2	3	2	3
LACTB WILD-TYPE	6	13	5	9	4	2

'CCDC102A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.131 (Fisher's exact test), Q value = 1

Table S17. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
CCDC102A MUTATED	4	7	0	3	3
CCDC102A WILD-TYPE	17	12	8	5	3

'CCDC102A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S18. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
CCDC102A MUTATED	3	2	4	4	3
CCDC102A WILD-TYPE	10	6	10	10	4

'CCDC102A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.911 (Fisher's exact test), Q value = 1

Table S19. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
CCDC102A MUTATED	4	3	4	5
CCDC102A WILD-TYPE	13	5	10	11

'CCDC102A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S20. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
CCDC102A MUTATED	4	4	1	7
CCDC102A WILD-TYPE	12	12	4	11

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S21. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
CCDC102A MUTATED	7	2	7
CCDC102A WILD-TYPE	19	10	11

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S22. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
CCDC102A MUTATED	2	6	4	4	0
CCDC102A WILD-TYPE	11	13	4	10	2

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S23. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
CCDC102A MUTATED	7	3	6
CCDC102A WILD-TYPE	20	10	10

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.145 (Fisher's exact test), Q value = 1

Table S24. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
CCDC102A MUTATED	0	6	3	3	1	3
CCDC102A WILD-TYPE	9	11	4	9	5	2

'ZNF517 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S25. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
ZNF517 MUTATED	5	5	0	2	1
ZNF517 WILD-TYPE	16	14	8	6	5

'ZNF517 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S26. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
ZNF517 MUTATED	3	1	2	2	1
ZNF517 WILD-TYPE	10	7	12	12	6

'ZNF517 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.884 (Fisher's exact test), Q value = 1

Table S27. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
ZNF517 MUTATED	4	1	2	2
ZNF517 WILD-TYPE	13	7	12	14

'ZNF517 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S28. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
ZNF517 MUTATED	3	2	1	3
ZNF517 WILD-TYPE	13	14	4	15

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 1

Table S29. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
ZNF517 MUTATED	3	4	2
ZNF517 WILD-TYPE	23	8	16

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S30. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
ZNF517 MUTATED	1	3	1	4	0
ZNF517 WILD-TYPE	12	16	7	10	2

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S31. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
ZNF517 MUTATED	4	3	2
ZNF517 WILD-TYPE	23	10	14

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.427 (Fisher's exact test), Q value = 1

Table S32. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
ZNF517 MUTATED	0	2	1	4	1	1
ZNF517 WILD-TYPE	9	15	6	8	5	4

'TOR3A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.273 (Fisher's exact test), Q value = 1

Table S33. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
TOR3A MUTATED	5	3	0	3	0
TOR3A WILD-TYPE	16	16	8	5	6

'TOR3A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0221 (Fisher's exact test), Q value = 1

Table S34. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
TOR3A MUTATED	0	0	4	6	1
TOR3A WILD-TYPE	13	8	10	8	6

Figure S1. Get High-res Image Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'TOR3A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S35. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
TOR3A MUTATED	2	1	4	4
TOR3A WILD-TYPE	15	7	10	12

'TOR3A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0151 (Fisher's exact test), Q value = 1

Table S36. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
TOR3A MUTATED	0	3	3	5
TOR3A WILD-TYPE	16	13	2	13

Figure S2. Get High-res Image Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'TOR3A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S37. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
TOR3A MUTATED	5	2	4
TOR3A WILD-TYPE	21	10	14

'TOR3A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.868 (Fisher's exact test), Q value = 1

Table S38. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
TOR3A MUTATED	2	5	2	2	0
TOR3A WILD-TYPE	11	14	6	12	2

'TOR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.828 (Fisher's exact test), Q value = 1

Table S39. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
TOR3A MUTATED	5	2	4
TOR3A WILD-TYPE	22	11	12

'TOR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S40. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
TOR3A MUTATED	2	4	2	1	2	0
TOR3A WILD-TYPE	7	13	5	11	4	5

'USP42 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.725 (Fisher's exact test), Q value = 1

Table S41. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
USP42 MUTATED	5	4	2	2	3
USP42 WILD-TYPE	16	15	6	6	3

'USP42 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0487 (Fisher's exact test), Q value = 1

Table S42. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
USP42 MUTATED	2	4	0	3	2
USP42 WILD-TYPE	11	4	14	11	5

Figure S3. Get High-res Image Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'USP42 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S43. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
USP42 MUTATED	3	2	3	3
USP42 WILD-TYPE	14	6	11	13

'USP42 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S44. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
USP42 MUTATED	3	4	1	3
USP42 WILD-TYPE	13	12	4	15

'USP42 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.567 (Fisher's exact test), Q value = 1

Table S45. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
USP42 MUTATED	6	3	2
USP42 WILD-TYPE	20	9	16

'USP42 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S46. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
USP42 MUTATED	2	3	2	4	0
USP42 WILD-TYPE	11	16	6	10	2

'USP42 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S47. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
USP42 MUTATED	6	3	2
USP42 WILD-TYPE	21	10	14

'USP42 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.289 (Fisher's exact test), Q value = 1

Table S48. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
USP42 MUTATED	1	3	3	4	0	0
USP42 WILD-TYPE	8	14	4	8	6	5

'CLDN23 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.263 (Fisher's exact test), Q value = 1

Table S49. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
CLDN23 MUTATED	2	5	1	0	2
CLDN23 WILD-TYPE	19	14	7	8	4

'CLDN23 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.247 (Fisher's exact test), Q value = 1

Table S50. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
CLDN23 MUTATED	1	2	1	3	3
CLDN23 WILD-TYPE	12	6	13	11	4

'CLDN23 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0237 (Fisher's exact test), Q value = 1

Table S51. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
CLDN23 MUTATED	1	1	1	7
CLDN23 WILD-TYPE	16	7	13	9

Figure S4. Get High-res Image Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'CLDN23 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S52. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
CLDN23 MUTATED	3	1	0	6
CLDN23 WILD-TYPE	13	15	5	12

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0905 (Fisher's exact test), Q value = 1

Table S53. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
CLDN23 MUTATED	2	2	6
CLDN23 WILD-TYPE	24	10	12

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.19 (Fisher's exact test), Q value = 1

Table S54. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
CLDN23 MUTATED	1	4	3	1	1
CLDN23 WILD-TYPE	12	15	5	13	1

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.108 (Fisher's exact test), Q value = 1

Table S55. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
CLDN23 MUTATED	2	3	5
CLDN23 WILD-TYPE	25	10	11

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.322 (Fisher's exact test), Q value = 1

Table S56. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
CLDN23 MUTATED	0	4	2	1	1	2
CLDN23 WILD-TYPE	9	13	5	11	5	3

'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0216 (Fisher's exact test), Q value = 1

Table S57. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
TP53 MUTATED	4	1	2	5	1
TP53 WILD-TYPE	17	18	6	3	5

Figure S5. Get High-res Image Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S58. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
TP53 MUTATED	2	3	3	2	1
TP53 WILD-TYPE	11	5	11	12	6

'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0201 (Fisher's exact test), Q value = 1

Table S59. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
TP53 MUTATED	3	2	6	0
TP53 WILD-TYPE	14	6	8	16

Figure S6. Get High-res Image Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.666 (Fisher's exact test), Q value = 1

Table S60. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
TP53 MUTATED	4	4	1	2
TP53 WILD-TYPE	12	12	4	16

'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.018 (Fisher's exact test), Q value = 1

Table S61. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
TP53 MUTATED	7	4	0
TP53 WILD-TYPE	19	8	18

Figure S7. Get High-res Image Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S62. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
TP53 MUTATED	4	2	2	3	0
TP53 WILD-TYPE	9	17	6	11	2

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0416 (Fisher's exact test), Q value = 1

Table S63. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
TP53 MUTATED	7	4	0
TP53 WILD-TYPE	20	9	16

Figure S8. Get High-res Image Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.192 (Fisher's exact test), Q value = 1

Table S64. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
TP53 MUTATED	3	1	3	3	1	0
TP53 WILD-TYPE	6	16	4	9	5	5

'KCNK17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.103 (Fisher's exact test), Q value = 1

Table S65. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
KCNK17 MUTATED	2	1	1	3	2
KCNK17 WILD-TYPE	19	18	7	5	4

'KCNK17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0379 (Fisher's exact test), Q value = 1

Table S66. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
KCNK17 MUTATED	0	2	5	1	0
KCNK17 WILD-TYPE	13	6	9	13	7

Figure S9. Get High-res Image Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'KCNK17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0944 (Fisher's exact test), Q value = 1

Table S67. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
KCNK17 MUTATED	1	1	5	1
KCNK17 WILD-TYPE	16	7	9	15

'KCNK17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00996 (Fisher's exact test), Q value = 1

Table S68. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
KCNK17 MUTATED	0	6	1	1
KCNK17 WILD-TYPE	16	10	4	17

Figure S10. Get High-res Image Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S69. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
KCNK17 MUTATED	4	2	2
KCNK17 WILD-TYPE	22	10	16

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S70. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
KCNK17 MUTATED	3	1	2	2	0
KCNK17 WILD-TYPE	10	18	6	12	2

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S71. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
KCNK17 MUTATED	4	3	1
KCNK17 WILD-TYPE	23	10	15

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S72. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
KCNK17 MUTATED	3	1	1	2	0	1
KCNK17 WILD-TYPE	6	16	6	10	6	4

'LZTR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 1

Table S73. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
LZTR1 MUTATED	4	0	1	1	0
LZTR1 WILD-TYPE	17	19	7	7	6

'LZTR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.806 (Fisher's exact test), Q value = 1

Table S74. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
LZTR1 MUTATED	2	0	1	1	0
LZTR1 WILD-TYPE	11	8	13	13	7

'LZTR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0894 (Fisher's exact test), Q value = 1

Table S75. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
LZTR1 MUTATED	3	1	0	0
LZTR1 WILD-TYPE	14	7	14	16

'LZTR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.194 (Fisher's exact test), Q value = 1

Table S76. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
LZTR1 MUTATED	2	1	1	0
LZTR1 WILD-TYPE	14	15	4	18

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S77. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
LZTR1 MUTATED	3	1	0
LZTR1 WILD-TYPE	23	11	18

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0137 (Fisher's exact test), Q value = 1

Table S78. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
LZTR1 MUTATED	0	0	0	3	1
LZTR1 WILD-TYPE	13	19	8	11	1

Figure S11. Get High-res Image Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S79. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
LZTR1 MUTATED	3	1	0
LZTR1 WILD-TYPE	24	12	16

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0854 (Fisher's exact test), Q value = 1

Table S80. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
LZTR1 MUTATED	0	0	0	3	1	0
LZTR1 WILD-TYPE	9	17	7	9	5	5

'APOE MUTATION STATUS' versus 'CN_CNMF'

P value = 0.17 (Fisher's exact test), Q value = 1

Table S81. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
APOE MUTATED	1	2	1	3	0
APOE WILD-TYPE	20	17	7	5	6

'APOE MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.62 (Fisher's exact test), Q value = 1

Table S82. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
APOE MUTATED	1	0	3	2	0
APOE WILD-TYPE	12	8	11	12	7

'APOE MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0669 (Fisher's exact test), Q value = 1

Table S83. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
APOE MUTATED	2	0	4	0
APOE WILD-TYPE	15	8	10	16

'APOE MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S84. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
APOE MUTATED	1	3	1	1
APOE WILD-TYPE	15	13	4	17

'APOE MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 1

Table S85. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
APOE MUTATED	2	3	1
APOE WILD-TYPE	24	9	17

'APOE MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S86. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
APOE MUTATED	1	3	0	2	0
APOE WILD-TYPE	12	16	8	12	2

'APOE MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.027 (Fisher's exact test), Q value = 1

Table S87. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
APOE MUTATED	2	4	0
APOE WILD-TYPE	25	9	16

Figure S12. Get High-res Image Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'APOE MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S88. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
APOE MUTATED	0	2	1	2	1	0
APOE WILD-TYPE	9	15	6	10	5	5

'CCDC105 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.169 (Fisher's exact test), Q value = 1

Table S89. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
CCDC105 MUTATED	1	2	1	3	0
CCDC105 WILD-TYPE	20	17	7	5	6

'CCDC105 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00859 (Fisher's exact test), Q value = 1

Table S90. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
CCDC105 MUTATED	1	3	0	0	2
CCDC105 WILD-TYPE	12	5	14	14	5

Figure S13. Get High-res Image Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CCDC105 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S91. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
CCDC105 MUTATED	1	1	2	2
CCDC105 WILD-TYPE	16	7	12	14

'CCDC105 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.714 (Fisher's exact test), Q value = 1

Table S92. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
CCDC105 MUTATED	3	1	0	2
CCDC105 WILD-TYPE	13	15	5	16

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S93. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
CCDC105 MUTATED	3	1	2
CCDC105 WILD-TYPE	23	11	16

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0509 (Fisher's exact test), Q value = 1

Table S94. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
CCDC105 MUTATED	1	0	2	2	1
CCDC105 WILD-TYPE	12	19	6	12	1

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S95. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
CCDC105 MUTATED	3	2	1
CCDC105 WILD-TYPE	24	11	15

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.326 (Fisher's exact test), Q value = 1

Table S96. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
CCDC105 MUTATED	1	0	1	2	1	1
CCDC105 WILD-TYPE	8	17	6	10	5	4

'RINL MUTATION STATUS' versus 'CN_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 1

Table S97. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
RINL MUTATED	6	1	0	1	0
RINL WILD-TYPE	15	18	8	7	6

'RINL MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.701 (Fisher's exact test), Q value = 1

Table S98. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
RINL MUTATED	3	1	1	2	0
RINL WILD-TYPE	10	7	13	12	7

'RINL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S99. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
RINL MUTATED	4	1	1	1
RINL WILD-TYPE	13	7	13	15

'RINL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.294 (Fisher's exact test), Q value = 1

Table S100. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
RINL MUTATED	4	1	1	1
RINL WILD-TYPE	12	15	4	17

'RINL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S101. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
RINL MUTATED	3	2	2
RINL WILD-TYPE	23	10	16

'RINL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.166 (Fisher's exact test), Q value = 1

Table S102. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
RINL MUTATED	0	3	0	4	0
RINL WILD-TYPE	13	16	8	10	2

'RINL MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S103. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
RINL MUTATED	3	3	1
RINL WILD-TYPE	24	10	15

'RINL MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.187 (Fisher's exact test), Q value = 1

Table S104. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
RINL MUTATED	0	3	0	4	0	0
RINL WILD-TYPE	9	14	7	8	6	5

'MAL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S105. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
MAL2 MUTATED	4	5	2	1	0
MAL2 WILD-TYPE	17	14	6	7	6

'MAL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S106. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
MAL2 MUTATED	3	2	0	3	1
MAL2 WILD-TYPE	10	6	14	11	6

'MAL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S107. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
MAL2 MUTATED	4	2	0	3
MAL2 WILD-TYPE	13	6	14	13

'MAL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.518 (Fisher's exact test), Q value = 1

Table S108. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
MAL2 MUTATED	4	1	1	3
MAL2 WILD-TYPE	12	15	4	15

'MAL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.123 (Fisher's exact test), Q value = 1

Table S109. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
MAL2 MUTATED	2	4	3
MAL2 WILD-TYPE	24	8	15

'MAL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.277 (Fisher's exact test), Q value = 1

Table S110. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
MAL2 MUTATED	0	4	1	4	0
MAL2 WILD-TYPE	13	15	7	10	2

'MAL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S111. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
MAL2 MUTATED	3	3	3
MAL2 WILD-TYPE	24	10	13

'MAL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.321 (Fisher's exact test), Q value = 1

Table S112. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
MAL2 MUTATED	0	3	0	4	1	1
MAL2 WILD-TYPE	9	14	7	8	5	4

'LRIG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.654 (Fisher's exact test), Q value = 1

Table S113. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
LRIG1 MUTATED	5	4	3	2	3
LRIG1 WILD-TYPE	16	15	5	6	3

'LRIG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S114. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
LRIG1 MUTATED	3	2	2	4	1
LRIG1 WILD-TYPE	10	6	12	10	6

'LRIG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S115. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
LRIG1 MUTATED	3	2	3	3
LRIG1 WILD-TYPE	14	6	11	13

'LRIG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S116. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
LRIG1 MUTATED	3	2	1	5
LRIG1 WILD-TYPE	13	14	4	13

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 1

Table S117. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
LRIG1 MUTATED	4	5	3
LRIG1 WILD-TYPE	22	7	15

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.496 (Fisher's exact test), Q value = 1

Table S118. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
LRIG1 MUTATED	1	4	3	4	0
LRIG1 WILD-TYPE	12	15	5	10	2

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S119. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
LRIG1 MUTATED	5	4	3
LRIG1 WILD-TYPE	22	9	13

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S120. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
LRIG1 MUTATED	1	3	2	4	1	1
LRIG1 WILD-TYPE	8	14	5	8	5	4

'C19ORF10 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.633 (Fisher's exact test), Q value = 1

Table S121. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
C19ORF10 MUTATED	3	2	0	2	0
C19ORF10 WILD-TYPE	18	17	8	6	6

'C19ORF10 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S122. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
C19ORF10 MUTATED	2	1	3	0	0
C19ORF10 WILD-TYPE	11	7	11	14	7

'C19ORF10 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.235 (Fisher's exact test), Q value = 1

Table S123. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
C19ORF10 MUTATED	2	2	2	0
C19ORF10 WILD-TYPE	15	6	12	16

'C19ORF10 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.109 (Fisher's exact test), Q value = 1

Table S124. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
C19ORF10 MUTATED	2	4	0	0
C19ORF10 WILD-TYPE	14	12	5	18

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.55 (Fisher's exact test), Q value = 1

Table S125. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
C19ORF10 MUTATED	3	2	1
C19ORF10 WILD-TYPE	23	10	17

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.86 (Fisher's exact test), Q value = 1

Table S126. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
C19ORF10 MUTATED	2	2	0	2	0
C19ORF10 WILD-TYPE	11	17	8	12	2

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.287 (Fisher's exact test), Q value = 1

Table S127. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
C19ORF10 MUTATED	4	2	0
C19ORF10 WILD-TYPE	23	11	16

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S128. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
C19ORF10 MUTATED	2	2	0	2	0	0
C19ORF10 WILD-TYPE	7	15	7	10	6	5

'C10ORF95 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S129. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
C10ORF95 MUTATED	2	0	2	1	1
C10ORF95 WILD-TYPE	19	19	6	7	5

'C10ORF95 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.707 (Fisher's exact test), Q value = 1

Table S130. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
C10ORF95 MUTATED	1	0	3	1	1
C10ORF95 WILD-TYPE	12	8	11	13	6

'C10ORF95 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.557 (Fisher's exact test), Q value = 1

Table S131. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
C10ORF95 MUTATED	2	2	1	1
C10ORF95 WILD-TYPE	15	6	13	15

'C10ORF95 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S132. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
C10ORF95 MUTATED	1	2	1	2
C10ORF95 WILD-TYPE	15	14	4	16

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.75 (Fisher's exact test), Q value = 1

Table S133. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
C10ORF95 MUTATED	4	1	1
C10ORF95 WILD-TYPE	22	11	17

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S134. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
C10ORF95 MUTATED	1	2	1	1	1
C10ORF95 WILD-TYPE	12	17	7	13	1

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S135. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
C10ORF95 MUTATED	4	1	1
C10ORF95 WILD-TYPE	23	12	15

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S136. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
C10ORF95 MUTATED	1	1	1	1	2	0
C10ORF95 WILD-TYPE	8	16	6	11	4	5

'SYT8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S137. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
SYT8 MUTATED	1	4	2	1	1
SYT8 WILD-TYPE	20	15	6	7	5

'SYT8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S138. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
SYT8 MUTATED	0	2	2	1	1
SYT8 WILD-TYPE	13	6	12	13	6

'SYT8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0346 (Fisher's exact test), Q value = 1

Table S139. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
SYT8 MUTATED	0	3	1	2
SYT8 WILD-TYPE	17	5	13	14

Figure S14. Get High-res Image Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'SYT8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.147 (Fisher's exact test), Q value = 1

Table S140. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
SYT8 MUTATED	0	4	0	2
SYT8 WILD-TYPE	16	12	5	16

'SYT8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S141. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
SYT8 MUTATED	3	1	2
SYT8 WILD-TYPE	23	11	16

'SYT8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.216 (Fisher's exact test), Q value = 1

Table S142. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
SYT8 MUTATED	1	3	1	0	1
SYT8 WILD-TYPE	12	16	7	14	1

'SYT8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S143. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
SYT8 MUTATED	3	1	2
SYT8 WILD-TYPE	24	12	14

'SYT8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.643 (Fisher's exact test), Q value = 1

Table S144. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
SYT8 MUTATED	1	3	1	0	1	0
SYT8 WILD-TYPE	8	14	6	12	5	5

'IDUA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S145. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
IDUA MUTATED	4	1	1	2	1
IDUA WILD-TYPE	17	18	7	6	5

'IDUA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S146. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
IDUA MUTATED	2	1	3	2	0
IDUA WILD-TYPE	11	7	11	12	7

'IDUA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.345 (Fisher's exact test), Q value = 1

Table S147. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
IDUA MUTATED	4	2	1	1
IDUA WILD-TYPE	13	6	13	15

'IDUA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S148. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
IDUA MUTATED	3	3	1	1
IDUA WILD-TYPE	13	13	4	17

'IDUA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.122 (Fisher's exact test), Q value = 1

Table S149. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
IDUA MUTATED	3	4	1
IDUA WILD-TYPE	23	8	17

'IDUA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S150. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
IDUA MUTATED	1	3	0	4	0
IDUA WILD-TYPE	12	16	8	10	2

'IDUA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.196 (Fisher's exact test), Q value = 1

Table S151. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
IDUA MUTATED	3	4	1
IDUA WILD-TYPE	24	9	15

'IDUA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S152. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
IDUA MUTATED	1	2	0	3	2	0
IDUA WILD-TYPE	8	15	7	9	4	5

'HHIPL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 1

Table S153. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
HHIPL1 MUTATED	4	1	0	3	0
HHIPL1 WILD-TYPE	17	18	8	5	6

'HHIPL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 1

Table S154. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
HHIPL1 MUTATED	2	0	0	3	1
HHIPL1 WILD-TYPE	11	8	14	11	6

'HHIPL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.358 (Fisher's exact test), Q value = 1

Table S155. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
HHIPL1 MUTATED	4	0	1	1
HHIPL1 WILD-TYPE	13	8	13	15

'HHIPL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 1

Table S156. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
HHIPL1 MUTATED	2	1	2	1
HHIPL1 WILD-TYPE	14	15	3	17

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 1

Table S157. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
HHIPL1 MUTATED	4	2	0
HHIPL1 WILD-TYPE	22	10	18

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S158. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
HHIPL1 MUTATED	2	1	1	2	0
HHIPL1 WILD-TYPE	11	18	7	12	2

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.289 (Fisher's exact test), Q value = 1

Table S159. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
HHIPL1 MUTATED	4	2	0
HHIPL1 WILD-TYPE	23	11	16

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.201 (Fisher's exact test), Q value = 1

Table S160. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
HHIPL1 MUTATED	1	0	2	2	1	0
HHIPL1 WILD-TYPE	8	17	5	10	5	5

'ASPDH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 1

Table S161. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
ASPDH MUTATED	2	2	1	3	0
ASPDH WILD-TYPE	19	17	7	5	6

'ASPDH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S162. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
ASPDH MUTATED	3	1	3	1	0
ASPDH WILD-TYPE	10	7	11	13	7

'ASPDH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0203 (Fisher's exact test), Q value = 1

Table S163. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
ASPDH MUTATED	3	0	5	0
ASPDH WILD-TYPE	14	8	9	16

Figure S15. Get High-res Image Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'ASPDH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.344 (Fisher's exact test), Q value = 1

Table S164. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
ASPDH MUTATED	3	4	0	1
ASPDH WILD-TYPE	13	12	5	17

'ASPDH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S165. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
ASPDH MUTATED	5	2	1
ASPDH WILD-TYPE	21	10	17

'ASPDH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0277 (Fisher's exact test), Q value = 1

Table S166. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
ASPDH MUTATED	4	0	0	4	0
ASPDH WILD-TYPE	9	19	8	10	2

Figure S16. Get High-res Image Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'ASPDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.368 (Fisher's exact test), Q value = 1

Table S167. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
ASPDH MUTATED	6	1	1
ASPDH WILD-TYPE	21	12	15

'ASPDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0793 (Fisher's exact test), Q value = 1

Table S168. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
ASPDH MUTATED	2	0	1	4	0	1
ASPDH WILD-TYPE	7	17	6	8	6	4

'C1ORF106 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S169. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
C1ORF106 MUTATED	4	2	2	1	0
C1ORF106 WILD-TYPE	17	17	6	7	6

'C1ORF106 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S170. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
C1ORF106 MUTATED	3	0	2	1	2
C1ORF106 WILD-TYPE	10	8	12	13	5

'C1ORF106 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S171. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
C1ORF106 MUTATED	4	2	1	1
C1ORF106 WILD-TYPE	13	6	13	15

'C1ORF106 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S172. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
C1ORF106 MUTATED	3	2	1	2
C1ORF106 WILD-TYPE	13	14	4	16

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.478 (Fisher's exact test), Q value = 1

Table S173. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
C1ORF106 MUTATED	5	2	1
C1ORF106 WILD-TYPE	21	10	17

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.689 (Fisher's exact test), Q value = 1

Table S174. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
C1ORF106 MUTATED	1	2	2	3	0
C1ORF106 WILD-TYPE	12	17	6	11	2

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.616 (Fisher's exact test), Q value = 1

Table S175. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
C1ORF106 MUTATED	5	2	1
C1ORF106 WILD-TYPE	22	11	15

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S176. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
C1ORF106 MUTATED	1	2	1	2	1	1
C1ORF106 WILD-TYPE	8	15	6	10	5	4

'THEM4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00358 (Fisher's exact test), Q value = 1

Table S177. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
THEM4 MUTATED	1	0	1	4	0
THEM4 WILD-TYPE	20	19	7	4	6

Figure S17. Get High-res Image Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'THEM4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S178. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
THEM4 MUTATED	1	1	1	0	1
THEM4 WILD-TYPE	12	7	13	14	6

'THEM4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.437 (Fisher's exact test), Q value = 1

Table S179. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
THEM4 MUTATED	1	1	2	0
THEM4 WILD-TYPE	16	7	12	16

'THEM4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.886 (Fisher's exact test), Q value = 1

Table S180. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
THEM4 MUTATED	2	1	0	1
THEM4 WILD-TYPE	14	15	5	17

'THEM4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.245 (Fisher's exact test), Q value = 1

Table S181. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
THEM4 MUTATED	2	2	0
THEM4 WILD-TYPE	24	10	18

'THEM4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0938 (Fisher's exact test), Q value = 1

Table S182. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
THEM4 MUTATED	0	0	1	3	0
THEM4 WILD-TYPE	13	19	7	11	2

'THEM4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.25 (Fisher's exact test), Q value = 1

Table S183. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
THEM4 MUTATED	2	2	0
THEM4 WILD-TYPE	25	11	16

'THEM4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.111 (Fisher's exact test), Q value = 1

Table S184. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
THEM4 MUTATED	0	0	1	3	0	0
THEM4 WILD-TYPE	9	17	6	9	6	5

'CTNNB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S185. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
CTNNB1 MUTATED	3	2	1	1	0
CTNNB1 WILD-TYPE	18	17	7	7	6

'CTNNB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 1

Table S186. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
CTNNB1 MUTATED	3	2	1	0	0
CTNNB1 WILD-TYPE	10	6	13	14	7

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0194 (Fisher's exact test), Q value = 1

Table S187. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
CTNNB1 MUTATED	4	2	0	0
CTNNB1 WILD-TYPE	13	6	14	16

Figure S18. Get High-res Image Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0181 (Fisher's exact test), Q value = 1

Table S188. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
CTNNB1 MUTATED	5	1	0	0
CTNNB1 WILD-TYPE	11	15	5	18

Figure S19. Get High-res Image Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00174 (Fisher's exact test), Q value = 1

Table S189. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
CTNNB1 MUTATED	1	5	0
CTNNB1 WILD-TYPE	25	7	18

Figure S20. Get High-res Image Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.169 (Fisher's exact test), Q value = 1

Table S190. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
CTNNB1 MUTATED	0	2	0	4	0
CTNNB1 WILD-TYPE	13	17	8	10	2

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0272 (Fisher's exact test), Q value = 1

Table S191. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
CTNNB1 MUTATED	2	4	0
CTNNB1 WILD-TYPE	25	9	16

Figure S21. Get High-res Image Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.48 (Fisher's exact test), Q value = 1

Table S192. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
CTNNB1 MUTATED	0	2	0	3	1	0
CTNNB1 WILD-TYPE	9	15	7	9	5	5

'GDF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S193. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
GDF1 MUTATED	1	2	0	2	0
GDF1 WILD-TYPE	20	17	8	6	6

'GDF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.312 (Fisher's exact test), Q value = 1

Table S194. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
GDF1 MUTATED	0	0	3	1	0
GDF1 WILD-TYPE	13	8	11	13	7

'GDF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.362 (Fisher's exact test), Q value = 1

Table S195. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
GDF1 MUTATED	0	1	2	1
GDF1 WILD-TYPE	17	7	12	15

'GDF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.254 (Fisher's exact test), Q value = 1

Table S196. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
GDF1 MUTATED	0	3	0	1
GDF1 WILD-TYPE	16	13	5	17

'GDF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0896 (Fisher's exact test), Q value = 1

Table S197. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
GDF1 MUTATED	0	2	2
GDF1 WILD-TYPE	26	10	16

'GDF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S198. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
GDF1 MUTATED	0	3	0	1	0
GDF1 WILD-TYPE	13	16	8	13	2

'GDF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0192 (Fisher's exact test), Q value = 1

Table S199. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
GDF1 MUTATED	0	3	1
GDF1 WILD-TYPE	27	10	15

Figure S22. Get High-res Image Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'GDF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S200. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
GDF1 MUTATED	0	3	0	1	0	0
GDF1 WILD-TYPE	9	14	7	11	6	5

'TSC22D2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S201. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
TSC22D2 MUTATED	4	1	0	2	1
TSC22D2 WILD-TYPE	17	18	8	6	5

'TSC22D2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S202. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
TSC22D2 MUTATED	2	0	2	1	2
TSC22D2 WILD-TYPE	11	8	12	13	5

'TSC22D2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.815 (Fisher's exact test), Q value = 1

Table S203. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
TSC22D2 MUTATED	3	0	2	2
TSC22D2 WILD-TYPE	14	8	12	14

'TSC22D2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.942 (Fisher's exact test), Q value = 1

Table S204. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
TSC22D2 MUTATED	2	2	1	2
TSC22D2 WILD-TYPE	14	14	4	16

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S205. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
TSC22D2 MUTATED	3	2	2
TSC22D2 WILD-TYPE	23	10	16

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.426 (Fisher's exact test), Q value = 1

Table S206. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
TSC22D2 MUTATED	1	2	0	4	0
TSC22D2 WILD-TYPE	12	17	8	10	2

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S207. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
TSC22D2 MUTATED	3	2	2
TSC22D2 WILD-TYPE	24	11	14

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.334 (Fisher's exact test), Q value = 1

Table S208. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
TSC22D2 MUTATED	1	2	0	4	0	0
TSC22D2 WILD-TYPE	8	15	7	8	6	5

'ZAR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.175 (Fisher's exact test), Q value = 1

Table S209. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
ZAR1 MUTATED	3	3	0	2	3
ZAR1 WILD-TYPE	18	16	8	6	3

'ZAR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S210. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
ZAR1 MUTATED	3	1	1	2	2
ZAR1 WILD-TYPE	10	7	13	12	5

'ZAR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.602 (Fisher's exact test), Q value = 1

Table S211. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
ZAR1 MUTATED	3	0	2	4
ZAR1 WILD-TYPE	14	8	12	12

'ZAR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S212. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
ZAR1 MUTATED	3	2	0	4
ZAR1 WILD-TYPE	13	14	5	14

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S213. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
ZAR1 MUTATED	4	1	4
ZAR1 WILD-TYPE	22	11	14

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S214. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
ZAR1 MUTATED	2	4	1	2	0
ZAR1 WILD-TYPE	11	15	7	12	2

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.52 (Fisher's exact test), Q value = 1

Table S215. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
ZAR1 MUTATED	4	1	4
ZAR1 WILD-TYPE	23	12	12

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S216. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
ZAR1 MUTATED	2	4	0	2	0	1
ZAR1 WILD-TYPE	7	13	7	10	6	4

'RGS9BP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.295 (Fisher's exact test), Q value = 1

Table S217. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
RGS9BP MUTATED	1	3	2	2	0
RGS9BP WILD-TYPE	20	16	6	6	6

'RGS9BP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.585 (Fisher's exact test), Q value = 1

Table S218. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
RGS9BP MUTATED	3	0	3	1	1
RGS9BP WILD-TYPE	10	8	11	13	6

'RGS9BP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S219. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
RGS9BP MUTATED	2	1	2	2
RGS9BP WILD-TYPE	15	7	12	14

'RGS9BP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S220. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
RGS9BP MUTATED	2	3	0	2
RGS9BP WILD-TYPE	14	13	5	16

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.335 (Fisher's exact test), Q value = 1

Table S221. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
RGS9BP MUTATED	2	3	3
RGS9BP WILD-TYPE	24	9	15

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S222. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
RGS9BP MUTATED	2	2	1	3	0
RGS9BP WILD-TYPE	11	17	7	11	2

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.884 (Fisher's exact test), Q value = 1

Table S223. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
RGS9BP MUTATED	3	2	3
RGS9BP WILD-TYPE	24	11	13

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S224. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
RGS9BP MUTATED	1	2	0	3	0	2
RGS9BP WILD-TYPE	8	15	7	9	6	3

'OPRD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S225. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
OPRD1 MUTATED	5	4	1	2	0
OPRD1 WILD-TYPE	16	15	7	6	6

'OPRD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.388 (Fisher's exact test), Q value = 1

Table S226. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
OPRD1 MUTATED	3	1	3	1	3
OPRD1 WILD-TYPE	10	7	11	13	4

'OPRD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.797 (Fisher's exact test), Q value = 1

Table S227. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
OPRD1 MUTATED	4	2	3	2
OPRD1 WILD-TYPE	13	6	11	14

'OPRD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.961 (Fisher's exact test), Q value = 1

Table S228. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
OPRD1 MUTATED	3	4	1	3
OPRD1 WILD-TYPE	13	12	4	15

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S229. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
OPRD1 MUTATED	5	4	2
OPRD1 WILD-TYPE	21	8	16

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S230. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
OPRD1 MUTATED	1	5	1	4	0
OPRD1 WILD-TYPE	12	14	7	10	2

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.469 (Fisher's exact test), Q value = 1

Table S231. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
OPRD1 MUTATED	5	4	2
OPRD1 WILD-TYPE	22	9	14

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S232. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
OPRD1 MUTATED	1	5	1	4	0	0
OPRD1 WILD-TYPE	8	12	6	8	6	5

'C16ORF3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S233. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
C16ORF3 MUTATED	2	2	0	1	1
C16ORF3 WILD-TYPE	19	17	8	7	5

'C16ORF3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00079 (Fisher's exact test), Q value = 0.78

Table S234. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
C16ORF3 MUTATED	0	4	0	0	1
C16ORF3 WILD-TYPE	13	4	14	14	6

Figure S23. Get High-res Image Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'C16ORF3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S235. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
C16ORF3 MUTATED	1	1	2	1
C16ORF3 WILD-TYPE	16	7	12	15

'C16ORF3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.831 (Fisher's exact test), Q value = 1

Table S236. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
C16ORF3 MUTATED	2	2	0	1
C16ORF3 WILD-TYPE	14	14	5	17

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S237. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
C16ORF3 MUTATED	2	2	1
C16ORF3 WILD-TYPE	24	10	17

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S238. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
C16ORF3 MUTATED	1	2	1	1	0
C16ORF3 WILD-TYPE	12	17	7	13	2

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S239. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
C16ORF3 MUTATED	2	2	1
C16ORF3 WILD-TYPE	25	11	15

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S240. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
C16ORF3 MUTATED	1	2	1	0	1	0
C16ORF3 WILD-TYPE	8	15	6	12	5	5

'FPGS MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S241. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
FPGS MUTATED	2	2	1	1	0
FPGS WILD-TYPE	19	17	7	7	6

'FPGS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S242. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
FPGS MUTATED	1	1	1	1	0
FPGS WILD-TYPE	12	7	13	13	7

'FPGS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S243. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
FPGS MUTATED	1	1	0	2
FPGS WILD-TYPE	16	7	14	14

'FPGS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S244. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
FPGS MUTATED	2	0	0	2
FPGS WILD-TYPE	14	16	5	16

'FPGS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0905 (Fisher's exact test), Q value = 1

Table S245. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
FPGS MUTATED	0	2	2
FPGS WILD-TYPE	26	10	16

'FPGS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S246. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
FPGS MUTATED	0	2	0	2	0
FPGS WILD-TYPE	13	17	8	12	2

'FPGS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S247. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
FPGS MUTATED	1	1	2
FPGS WILD-TYPE	26	12	14

'FPGS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S248. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
FPGS MUTATED	0	2	0	2	0	0
FPGS WILD-TYPE	9	15	7	10	6	5

'PLIN5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.561 (Fisher's exact test), Q value = 1

Table S249. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
PLIN5 MUTATED	1	3	0	1	0
PLIN5 WILD-TYPE	20	16	8	7	6

'PLIN5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.693 (Fisher's exact test), Q value = 1

Table S250. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
PLIN5 MUTATED	1	2	1	1	0
PLIN5 WILD-TYPE	12	6	13	13	7

'PLIN5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S251. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
PLIN5 MUTATED	1	1	2	1
PLIN5 WILD-TYPE	16	7	12	15

'PLIN5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S252. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
PLIN5 MUTATED	1	3	0	1
PLIN5 WILD-TYPE	15	13	5	17

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S253. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
PLIN5 MUTATED	1	2	2
PLIN5 WILD-TYPE	25	10	16

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.308 (Fisher's exact test), Q value = 1

Table S254. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
PLIN5 MUTATED	1	4	0	0	0
PLIN5 WILD-TYPE	12	15	8	14	2

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 1

Table S255. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
PLIN5 MUTATED	1	3	1
PLIN5 WILD-TYPE	26	10	15

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.321 (Fisher's exact test), Q value = 1

Table S256. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
PLIN5 MUTATED	1	4	0	0	0	0
PLIN5 WILD-TYPE	8	13	7	12	6	5

'IRX3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.333 (Fisher's exact test), Q value = 1

Table S257. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
IRX3 MUTATED	3	0	1	1	0
IRX3 WILD-TYPE	18	19	7	7	6

'IRX3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S258. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
IRX3 MUTATED	0	1	2	1	0
IRX3 WILD-TYPE	13	7	12	13	7

'IRX3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.52 (Fisher's exact test), Q value = 1

Table S259. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
IRX3 MUTATED	2	1	1	0
IRX3 WILD-TYPE	15	7	13	16

'IRX3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.193 (Fisher's exact test), Q value = 1

Table S260. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
IRX3 MUTATED	1	2	1	0
IRX3 WILD-TYPE	15	14	4	18

'IRX3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.246 (Fisher's exact test), Q value = 1

Table S261. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
IRX3 MUTATED	2	2	0
IRX3 WILD-TYPE	24	10	18

'IRX3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S262. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
IRX3 MUTATED	2	1	0	1	0
IRX3 WILD-TYPE	11	18	8	13	2

'IRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.25 (Fisher's exact test), Q value = 1

Table S263. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
IRX3 MUTATED	2	2	0
IRX3 WILD-TYPE	25	11	16

'IRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0204 (Fisher's exact test), Q value = 1

Table S264. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
IRX3 MUTATED	2	0	0	0	2	0
IRX3 WILD-TYPE	7	17	7	12	4	5

Figure S24. Get High-res Image Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'TRIOBP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.821 (Fisher's exact test), Q value = 1

Table S265. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
TRIOBP MUTATED	5	4	2	1	0
TRIOBP WILD-TYPE	16	15	6	7	6

'TRIOBP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 1

Table S266. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
TRIOBP MUTATED	3	1	0	4	2
TRIOBP WILD-TYPE	10	7	14	10	5

'TRIOBP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S267. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
TRIOBP MUTATED	3	1	2	3
TRIOBP WILD-TYPE	14	7	12	13

'TRIOBP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S268. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
TRIOBP MUTATED	3	0	1	5
TRIOBP WILD-TYPE	13	16	4	13

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.902 (Fisher's exact test), Q value = 1

Table S269. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
TRIOBP MUTATED	4	2	4
TRIOBP WILD-TYPE	22	10	14

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.93 (Fisher's exact test), Q value = 1

Table S270. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
TRIOBP MUTATED	2	3	2	3	0
TRIOBP WILD-TYPE	11	16	6	11	2

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S271. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
TRIOBP MUTATED	4	2	4
TRIOBP WILD-TYPE	23	11	12

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.746 (Fisher's exact test), Q value = 1

Table S272. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
TRIOBP MUTATED	1	2	1	3	1	2
TRIOBP WILD-TYPE	8	15	6	9	5	3

'KRTAP4-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S273. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
KRTAP4-5 MUTATED	2	3	0	0	0
KRTAP4-5 WILD-TYPE	19	16	8	8	6

'KRTAP4-5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.313 (Fisher's exact test), Q value = 1

Table S274. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
KRTAP4-5 MUTATED	1	2	0	1	0
KRTAP4-5 WILD-TYPE	12	6	14	13	7

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S275. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
KRTAP4-5 MUTATED	2	0	1	1
KRTAP4-5 WILD-TYPE	15	8	13	15

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.886 (Fisher's exact test), Q value = 1

Table S276. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
KRTAP4-5 MUTATED	2	1	0	1
KRTAP4-5 WILD-TYPE	14	15	5	17

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S277. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
KRTAP4-5 MUTATED	2	1	1
KRTAP4-5 WILD-TYPE	24	11	17

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S278. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
KRTAP4-5 MUTATED	1	1	0	2	0
KRTAP4-5 WILD-TYPE	12	18	8	12	2

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S279. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
KRTAP4-5 MUTATED	2	1	1
KRTAP4-5 WILD-TYPE	25	12	15

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S280. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
KRTAP4-5 MUTATED	1	1	0	1	1	0
KRTAP4-5 WILD-TYPE	8	16	7	11	5	5

'ATXN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.408 (Fisher's exact test), Q value = 1

Table S281. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
ATXN1 MUTATED	3	3	3	0	1
ATXN1 WILD-TYPE	18	16	5	8	5

'ATXN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 1

Table S282. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
ATXN1 MUTATED	1	4	2	1	1
ATXN1 WILD-TYPE	12	4	12	13	6

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 1

Table S283. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
ATXN1 MUTATED	2	3	3	1
ATXN1 WILD-TYPE	15	5	11	15

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.627 (Fisher's exact test), Q value = 1

Table S284. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
ATXN1 MUTATED	3	4	0	2
ATXN1 WILD-TYPE	13	12	5	16

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 1

Table S285. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
ATXN1 MUTATED	5	3	1
ATXN1 WILD-TYPE	21	9	17

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S286. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
ATXN1 MUTATED	2	2	2	3	0
ATXN1 WILD-TYPE	11	17	6	11	2

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.41 (Fisher's exact test), Q value = 1

Table S287. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
ATXN1 MUTATED	5	3	1
ATXN1 WILD-TYPE	22	10	15

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S288. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
ATXN1 MUTATED	2	2	2	2	1	0
ATXN1 WILD-TYPE	7	15	5	10	5	5

'ZNF628 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 1

Table S289. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
ZNF628 MUTATED	4	1	0	2	0
ZNF628 WILD-TYPE	17	18	8	6	6

'ZNF628 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.892 (Fisher's exact test), Q value = 1

Table S290. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
ZNF628 MUTATED	2	1	1	1	0
ZNF628 WILD-TYPE	11	7	13	13	7

'ZNF628 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S291. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
ZNF628 MUTATED	3	1	1	0
ZNF628 WILD-TYPE	14	7	13	16

'ZNF628 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.122 (Fisher's exact test), Q value = 1

Table S292. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
ZNF628 MUTATED	3	1	1	0
ZNF628 WILD-TYPE	13	15	4	18

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S293. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
ZNF628 MUTATED	1	3	1
ZNF628 WILD-TYPE	25	9	17

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.494 (Fisher's exact test), Q value = 1

Table S294. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
ZNF628 MUTATED	0	3	0	2	0
ZNF628 WILD-TYPE	13	16	8	12	2

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0953 (Fisher's exact test), Q value = 1

Table S295. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
ZNF628 MUTATED	2	3	0
ZNF628 WILD-TYPE	25	10	16

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.725 (Fisher's exact test), Q value = 1

Table S296. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
ZNF628 MUTATED	0	2	0	2	1	0
ZNF628 WILD-TYPE	9	15	7	10	5	5

'WDR34 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.674 (Fisher's exact test), Q value = 1

Table S297. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
WDR34 MUTATED	2	1	0	1	1
WDR34 WILD-TYPE	19	18	8	7	5

'WDR34 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S298. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
WDR34 MUTATED	2	0	1	1	1
WDR34 WILD-TYPE	11	8	13	13	6

'WDR34 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.931 (Fisher's exact test), Q value = 1

Table S299. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
WDR34 MUTATED	2	0	1	2
WDR34 WILD-TYPE	15	8	13	14

'WDR34 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S300. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
WDR34 MUTATED	2	2	0	1
WDR34 WILD-TYPE	14	14	5	17

'WDR34 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S301. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
WDR34 MUTATED	3	1	1
WDR34 WILD-TYPE	23	11	17

'WDR34 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S302. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
WDR34 MUTATED	1	1	0	3	0
WDR34 WILD-TYPE	12	18	8	11	2

'WDR34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S303. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
WDR34 MUTATED	3	1	1
WDR34 WILD-TYPE	24	12	15

'WDR34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S304. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
WDR34 MUTATED	0	1	1	3	0	0
WDR34 WILD-TYPE	9	16	6	9	6	5

'BTBD11 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S305. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
BTBD11 MUTATED	2	2	1	1	0
BTBD11 WILD-TYPE	19	17	7	7	6

'BTBD11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.235 (Fisher's exact test), Q value = 1

Table S306. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
BTBD11 MUTATED	1	1	1	0	2
BTBD11 WILD-TYPE	12	7	13	14	5

'BTBD11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.48 (Fisher's exact test), Q value = 1

Table S307. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
BTBD11 MUTATED	1	0	3	1
BTBD11 WILD-TYPE	16	8	11	15

'BTBD11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S308. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
BTBD11 MUTATED	1	2	0	2
BTBD11 WILD-TYPE	15	14	5	16

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.493 (Fisher's exact test), Q value = 1

Table S309. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
BTBD11 MUTATED	4	0	1
BTBD11 WILD-TYPE	22	12	17

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.165 (Fisher's exact test), Q value = 1

Table S310. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
BTBD11 MUTATED	2	0	2	1	0
BTBD11 WILD-TYPE	11	19	6	13	2

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S311. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
BTBD11 MUTATED	4	0	1
BTBD11 WILD-TYPE	23	13	15

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.213 (Fisher's exact test), Q value = 1

Table S312. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
BTBD11 MUTATED	2	0	1	1	0	1
BTBD11 WILD-TYPE	7	17	6	11	6	4

'GARS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 1

Table S313. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
GARS MUTATED	6	4	3	4	4
GARS WILD-TYPE	15	15	5	4	2

'GARS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0685 (Fisher's exact test), Q value = 1

Table S314. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
GARS MUTATED	2	0	4	6	4
GARS WILD-TYPE	11	8	10	8	3

'GARS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.433 (Fisher's exact test), Q value = 1

Table S315. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
GARS MUTATED	4	1	4	7
GARS WILD-TYPE	13	7	10	9

'GARS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.063 (Fisher's exact test), Q value = 1

Table S316. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
GARS MUTATED	2	3	3	8
GARS WILD-TYPE	14	13	2	10

'GARS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.238 (Fisher's exact test), Q value = 1

Table S317. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
GARS MUTATED	6	2	8
GARS WILD-TYPE	20	10	10

'GARS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S318. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
GARS MUTATED	3	7	4	2	0
GARS WILD-TYPE	10	12	4	12	2

'GARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0989 (Fisher's exact test), Q value = 1

Table S319. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
GARS MUTATED	6	2	8
GARS WILD-TYPE	21	11	8

'GARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S320. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
GARS MUTATED	2	6	2	1	2	3
GARS WILD-TYPE	7	11	5	11	4	2

'ZNF598 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S321. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
ZNF598 MUTATED	6	2	1	3	1
ZNF598 WILD-TYPE	15	17	7	5	5

'ZNF598 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S322. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
ZNF598 MUTATED	3	0	2	4	0
ZNF598 WILD-TYPE	10	8	12	10	7

'ZNF598 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.534 (Fisher's exact test), Q value = 1

Table S323. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
ZNF598 MUTATED	4	0	3	2
ZNF598 WILD-TYPE	13	8	11	14

'ZNF598 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S324. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
ZNF598 MUTATED	3	2	1	3
ZNF598 WILD-TYPE	13	14	4	15

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S325. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
ZNF598 MUTATED	4	2	3
ZNF598 WILD-TYPE	22	10	15

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.215 (Fisher's exact test), Q value = 1

Table S326. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
ZNF598 MUTATED	1	3	0	5	0
ZNF598 WILD-TYPE	12	16	8	9	2

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S327. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
ZNF598 MUTATED	4	2	3
ZNF598 WILD-TYPE	23	11	13

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.162 (Fisher's exact test), Q value = 1

Table S328. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
ZNF598 MUTATED	1	3	0	5	0	0
ZNF598 WILD-TYPE	8	14	7	7	6	5

'BHLHE22 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.391 (Fisher's exact test), Q value = 1

Table S329. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
BHLHE22 MUTATED	1	2	2	0	0
BHLHE22 WILD-TYPE	20	17	6	8	6

'BHLHE22 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0641 (Fisher's exact test), Q value = 1

Table S330. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
BHLHE22 MUTATED	0	3	1	1	0
BHLHE22 WILD-TYPE	13	5	13	13	7

'BHLHE22 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 1

Table S331. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
BHLHE22 MUTATED	0	2	2	1
BHLHE22 WILD-TYPE	17	6	12	15

'BHLHE22 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.83 (Fisher's exact test), Q value = 1

Table S332. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
BHLHE22 MUTATED	2	2	0	1
BHLHE22 WILD-TYPE	14	14	5	17

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.595 (Fisher's exact test), Q value = 1

Table S333. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
BHLHE22 MUTATED	2	2	1
BHLHE22 WILD-TYPE	24	10	17

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S334. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
BHLHE22 MUTATED	2	2	0	1	0
BHLHE22 WILD-TYPE	11	17	8	13	2

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S335. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
BHLHE22 MUTATED	2	2	1
BHLHE22 WILD-TYPE	25	11	15

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S336. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
BHLHE22 MUTATED	2	2	0	1	0	0
BHLHE22 WILD-TYPE	7	15	7	11	6	5

'PTPLA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S337. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
PTPLA MUTATED	2	0	1	1	0
PTPLA WILD-TYPE	19	19	7	7	6

'PTPLA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.292 (Fisher's exact test), Q value = 1

Table S338. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
PTPLA MUTATED	0	1	2	0	0
PTPLA WILD-TYPE	13	7	12	14	7

'PTPLA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.332 (Fisher's exact test), Q value = 1

Table S339. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
PTPLA MUTATED	1	0	2	0
PTPLA WILD-TYPE	16	8	12	16

'PTPLA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S340. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
PTPLA MUTATED	1	2	0	0
PTPLA WILD-TYPE	15	14	5	18

'PTPLA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S341. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
PTPLA MUTATED	1	1	1
PTPLA WILD-TYPE	25	11	17

'PTPLA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S342. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
PTPLA MUTATED	1	1	0	1	0
PTPLA WILD-TYPE	12	18	8	13	2

'PTPLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S343. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
PTPLA MUTATED	1	2	0
PTPLA WILD-TYPE	26	11	16

'PTPLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.583 (Fisher's exact test), Q value = 1

Table S344. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
PTPLA MUTATED	1	1	0	0	1	0
PTPLA WILD-TYPE	8	16	7	12	5	5

'CD320 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S345. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
CD320 MUTATED	2	1	1	0	0
CD320 WILD-TYPE	19	18	7	8	6

'CD320 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.897 (Fisher's exact test), Q value = 1

Table S346. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
CD320 MUTATED	1	0	1	2	0
CD320 WILD-TYPE	12	8	13	12	7

'CD320 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.737 (Fisher's exact test), Q value = 1

Table S347. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
CD320 MUTATED	1	0	2	1
CD320 WILD-TYPE	16	8	12	15

'CD320 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S348. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
CD320 MUTATED	1	1	1	1
CD320 WILD-TYPE	15	15	4	17

'CD320 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.416 (Fisher's exact test), Q value = 1

Table S349. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
CD320 MUTATED	3	1	0
CD320 WILD-TYPE	23	11	18

'CD320 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.221 (Fisher's exact test), Q value = 1

Table S350. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
CD320 MUTATED	1	0	2	1	0
CD320 WILD-TYPE	12	19	6	13	2

'CD320 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.175 (Fisher's exact test), Q value = 1

Table S351. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
CD320 MUTATED	4	0	0
CD320 WILD-TYPE	23	13	16

'CD320 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S352. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
CD320 MUTATED	1	0	2	1	0	0
CD320 WILD-TYPE	8	17	5	11	6	5

'KIAA1984 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.252 (Fisher's exact test), Q value = 1

Table S353. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
KIAA1984 MUTATED	1	0	1	1	1
KIAA1984 WILD-TYPE	20	19	7	7	5

'KIAA1984 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.735 (Fisher's exact test), Q value = 1

Table S354. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
KIAA1984 MUTATED	0	1	2	1	0
KIAA1984 WILD-TYPE	13	7	12	13	7

'KIAA1984 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 1

Table S355. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
KIAA1984 MUTATED	1	0	3	0
KIAA1984 WILD-TYPE	16	8	11	16

'KIAA1984 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0463 (Fisher's exact test), Q value = 1

Table S356. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
KIAA1984 MUTATED	0	3	1	0
KIAA1984 WILD-TYPE	16	13	4	18

Figure S25. Get High-res Image Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0364 (Fisher's exact test), Q value = 1

Table S357. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
KIAA1984 MUTATED	1	3	0
KIAA1984 WILD-TYPE	25	9	18

Figure S26. Get High-res Image Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S358. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
KIAA1984 MUTATED	0	1	1	2	0
KIAA1984 WILD-TYPE	13	18	7	12	2

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0617 (Fisher's exact test), Q value = 1

Table S359. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
KIAA1984 MUTATED	1	3	0
KIAA1984 WILD-TYPE	26	10	16

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.669 (Fisher's exact test), Q value = 1

Table S360. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
KIAA1984 MUTATED	0	1	1	2	0	0
KIAA1984 WILD-TYPE	9	16	6	10	6	5

'TPO MUTATION STATUS' versus 'CN_CNMF'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S361. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
TPO MUTATED	6	2	1	1	2
TPO WILD-TYPE	15	17	7	7	4

'TPO MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 1

Table S362. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
TPO MUTATED	3	3	1	2	0
TPO WILD-TYPE	10	5	13	12	7

'TPO MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.214 (Fisher's exact test), Q value = 1

Table S363. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
TPO MUTATED	5	2	1	1
TPO WILD-TYPE	12	6	13	15

'TPO MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.159 (Fisher's exact test), Q value = 1

Table S364. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
TPO MUTATED	4	2	2	1
TPO WILD-TYPE	12	14	3	17

'TPO MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.14 (Fisher's exact test), Q value = 1

Table S365. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
TPO MUTATED	4	4	1
TPO WILD-TYPE	22	8	17

'TPO MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.319 (Fisher's exact test), Q value = 1

Table S366. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
TPO MUTATED	1	2	1	5	0
TPO WILD-TYPE	12	17	7	9	2

'TPO MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.28 (Fisher's exact test), Q value = 1

Table S367. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
TPO MUTATED	4	4	1
TPO WILD-TYPE	23	9	15

'TPO MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.122 (Fisher's exact test), Q value = 1

Table S368. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
TPO MUTATED	1	1	0	5	1	1
TPO WILD-TYPE	8	16	7	7	5	4

'AATK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 1

Table S369. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
AATK MUTATED	0	4	1	0	1
AATK WILD-TYPE	21	15	7	8	5

'AATK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S370. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
AATK MUTATED	0	1	2	0	1
AATK WILD-TYPE	13	7	12	14	6

'AATK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 1

Table S371. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
AATK MUTATED	0	1	2	1
AATK WILD-TYPE	17	7	12	15

'AATK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.251 (Fisher's exact test), Q value = 1

Table S372. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
AATK MUTATED	0	3	0	1
AATK WILD-TYPE	16	13	5	17

'AATK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S373. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
AATK MUTATED	2	1	1
AATK WILD-TYPE	24	11	17

'AATK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.506 (Fisher's exact test), Q value = 1

Table S374. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
AATK MUTATED	2	2	0	0	0
AATK WILD-TYPE	11	17	8	14	2

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S375. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
AATK MUTATED	2	1	1
AATK WILD-TYPE	25	12	15

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S376. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
AATK MUTATED	2	2	0	0	0	0
AATK WILD-TYPE	7	15	7	12	6	5

'PANK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.735 (Fisher's exact test), Q value = 1

Table S377. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
PANK2 MUTATED	3	1	0	1	0
PANK2 WILD-TYPE	18	18	8	7	6

'PANK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S378. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
PANK2 MUTATED	2	0	0	1	0
PANK2 WILD-TYPE	11	8	14	13	7

'PANK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S379. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
PANK2 MUTATED	3	0	0	0
PANK2 WILD-TYPE	14	8	14	16

'PANK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.108 (Fisher's exact test), Q value = 1

Table S380. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
PANK2 MUTATED	2	0	1	0
PANK2 WILD-TYPE	14	16	4	18

'PANK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S381. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
PANK2 MUTATED	2	1	0
PANK2 WILD-TYPE	24	11	18

'PANK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S382. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
PANK2 MUTATED	1	0	0	2	0
PANK2 WILD-TYPE	12	19	8	12	2

'PANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S383. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
PANK2 MUTATED	2	1	0
PANK2 WILD-TYPE	25	12	16

'PANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.323 (Fisher's exact test), Q value = 1

Table S384. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
PANK2 MUTATED	1	0	0	2	0	0
PANK2 WILD-TYPE	8	17	7	10	6	5

'SNED1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S385. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
SNED1 MUTATED	4	1	0	0	1
SNED1 WILD-TYPE	17	18	8	8	5

'SNED1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S386. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
SNED1 MUTATED	2	2	1	1	0
SNED1 WILD-TYPE	11	6	13	13	7

'SNED1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.212 (Fisher's exact test), Q value = 1

Table S387. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
SNED1 MUTATED	4	1	0	1
SNED1 WILD-TYPE	13	7	14	15

'SNED1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S388. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
SNED1 MUTATED	3	1	1	1
SNED1 WILD-TYPE	13	15	4	17

'SNED1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0442 (Fisher's exact test), Q value = 1

Table S389. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
SNED1 MUTATED	1	4	1
SNED1 WILD-TYPE	25	8	17

Figure S27. Get High-res Image Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'SNED1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.649 (Fisher's exact test), Q value = 1

Table S390. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
SNED1 MUTATED	0	3	1	2	0
SNED1 WILD-TYPE	13	16	7	12	2

'SNED1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0459 (Fisher's exact test), Q value = 1

Table S391. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
SNED1 MUTATED	1	4	1
SNED1 WILD-TYPE	26	9	15

Figure S28. Get High-res Image Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'SNED1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.321 (Fisher's exact test), Q value = 1

Table S392. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
SNED1 MUTATED	0	2	0	1	2	1
SNED1 WILD-TYPE	9	15	7	11	4	4

'CCDC150 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S393. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
CCDC150 MUTATED	2	0	1	1	0
CCDC150 WILD-TYPE	19	19	7	7	6

'CCDC150 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.808 (Fisher's exact test), Q value = 1

Table S394. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
CCDC150 MUTATED	2	0	1	1	0
CCDC150 WILD-TYPE	11	8	13	13	7

'CCDC150 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.265 (Fisher's exact test), Q value = 1

Table S395. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
CCDC150 MUTATED	3	0	1	0
CCDC150 WILD-TYPE	14	8	13	16

'CCDC150 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.197 (Fisher's exact test), Q value = 1

Table S396. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
CCDC150 MUTATED	2	1	1	0
CCDC150 WILD-TYPE	14	15	4	18

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S397. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
CCDC150 MUTATED	3	1	0
CCDC150 WILD-TYPE	23	11	18

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S398. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
CCDC150 MUTATED	1	0	0	3	0
CCDC150 WILD-TYPE	12	19	8	11	2

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S399. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
CCDC150 MUTATED	3	1	0
CCDC150 WILD-TYPE	24	12	16

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.143 (Fisher's exact test), Q value = 1

Table S400. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
CCDC150 MUTATED	1	0	0	3	0	0
CCDC150 WILD-TYPE	8	17	7	9	6	5

'ERCC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.756 (Fisher's exact test), Q value = 1

Table S401. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
ERCC2 MUTATED	3	3	2	2	0
ERCC2 WILD-TYPE	18	16	6	6	6

'ERCC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.196 (Fisher's exact test), Q value = 1

Table S402. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
ERCC2 MUTATED	4	3	2	1	0
ERCC2 WILD-TYPE	9	5	12	13	7

'ERCC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S403. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
ERCC2 MUTATED	4	2	3	1
ERCC2 WILD-TYPE	13	6	11	15

'ERCC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.149 (Fisher's exact test), Q value = 1

Table S404. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
ERCC2 MUTATED	5	4	0	1
ERCC2 WILD-TYPE	11	12	5	17

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S405. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
ERCC2 MUTATED	6	2	2
ERCC2 WILD-TYPE	20	10	16

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.239 (Fisher's exact test), Q value = 1

Table S406. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
ERCC2 MUTATED	3	2	0	5	0
ERCC2 WILD-TYPE	10	17	8	9	2

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.29 (Fisher's exact test), Q value = 1

Table S407. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
ERCC2 MUTATED	7	2	1
ERCC2 WILD-TYPE	20	11	15

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0884 (Fisher's exact test), Q value = 1

Table S408. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
ERCC2 MUTATED	3	2	0	5	0	0
ERCC2 WILD-TYPE	6	15	7	7	6	5

'RREB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.736 (Fisher's exact test), Q value = 1

Table S409. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
RREB1 MUTATED	3	1	1	0	0
RREB1 WILD-TYPE	18	18	7	8	6

'RREB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.807 (Fisher's exact test), Q value = 1

Table S410. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
RREB1 MUTATED	2	0	1	1	0
RREB1 WILD-TYPE	11	8	13	13	7

'RREB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S411. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
RREB1 MUTATED	1	1	1	0
RREB1 WILD-TYPE	16	7	13	16

'RREB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S412. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
RREB1 MUTATED	1	1	0	1
RREB1 WILD-TYPE	15	15	5	17

'RREB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S413. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
RREB1 MUTATED	1	1	2
RREB1 WILD-TYPE	25	11	16

'RREB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.504 (Fisher's exact test), Q value = 1

Table S414. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
RREB1 MUTATED	2	2	0	0	0
RREB1 WILD-TYPE	11	17	8	14	2

'RREB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S415. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
RREB1 MUTATED	1	1	2
RREB1 WILD-TYPE	26	12	14

'RREB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S416. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
RREB1 MUTATED	1	2	0	0	0	1
RREB1 WILD-TYPE	8	15	7	12	6	4

'RNF39 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.427 (Fisher's exact test), Q value = 1

Table S417. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
RNF39 MUTATED	2	1	0	2	0
RNF39 WILD-TYPE	19	18	8	6	6

'RNF39 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 1

Table S418. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
RNF39 MUTATED	1	2	2	0	0
RNF39 WILD-TYPE	12	6	12	14	7

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 1

Table S419. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
RNF39 MUTATED	1	1	3	0
RNF39 WILD-TYPE	16	7	11	16

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.267 (Fisher's exact test), Q value = 1

Table S420. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
RNF39 MUTATED	2	3	0	0
RNF39 WILD-TYPE	14	13	5	18

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 1

Table S421. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
RNF39 MUTATED	3	2	0
RNF39 WILD-TYPE	23	10	18

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S422. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
RNF39 MUTATED	2	1	0	2	0
RNF39 WILD-TYPE	11	18	8	12	2

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S423. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
RNF39 MUTATED	3	2	0
RNF39 WILD-TYPE	24	11	16

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S424. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
RNF39 MUTATED	2	1	0	2	0	0
RNF39 WILD-TYPE	7	16	7	10	6	5

'SEMA5B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S425. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
SEMA5B MUTATED	5	2	0	0	1
SEMA5B WILD-TYPE	16	17	8	8	5

'SEMA5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S426. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
SEMA5B MUTATED	2	1	0	3	0
SEMA5B WILD-TYPE	11	7	14	11	7

'SEMA5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S427. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
SEMA5B MUTATED	3	1	0	2
SEMA5B WILD-TYPE	14	7	14	14

'SEMA5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.274 (Fisher's exact test), Q value = 1

Table S428. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
SEMA5B MUTATED	3	0	1	2
SEMA5B WILD-TYPE	13	16	4	16

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S429. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
SEMA5B MUTATED	2	2	2
SEMA5B WILD-TYPE	24	10	16

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.337 (Fisher's exact test), Q value = 1

Table S430. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
SEMA5B MUTATED	0	4	0	2	0
SEMA5B WILD-TYPE	13	15	8	12	2

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.637 (Fisher's exact test), Q value = 1

Table S431. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
SEMA5B MUTATED	2	2	2
SEMA5B WILD-TYPE	25	11	14

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.666 (Fisher's exact test), Q value = 1

Table S432. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
SEMA5B MUTATED	0	3	0	2	1	0
SEMA5B WILD-TYPE	9	14	7	10	5	5

'TAF5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.937 (Fisher's exact test), Q value = 1

Table S433. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
TAF5 MUTATED	2	1	1	0	0
TAF5 WILD-TYPE	19	18	7	8	6

'TAF5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S434. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
TAF5 MUTATED	1	1	1	0	1
TAF5 WILD-TYPE	12	7	13	14	6

'TAF5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S435. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
TAF5 MUTATED	1	1	1	1
TAF5 WILD-TYPE	16	7	13	15

'TAF5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.884 (Fisher's exact test), Q value = 1

Table S436. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
TAF5 MUTATED	2	1	0	1
TAF5 WILD-TYPE	14	15	5	17

'TAF5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0212 (Fisher's exact test), Q value = 1

Table S437. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
TAF5 MUTATED	0	3	1
TAF5 WILD-TYPE	26	9	17

Figure S29. Get High-res Image Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'TAF5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.121 (Fisher's exact test), Q value = 1

Table S438. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
TAF5 MUTATED	0	4	0	0	0
TAF5 WILD-TYPE	13	15	8	14	2

'TAF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0195 (Fisher's exact test), Q value = 1

Table S439. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
TAF5 MUTATED	0	3	1
TAF5 WILD-TYPE	27	10	15

Figure S30. Get High-res Image Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'TAF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.197 (Fisher's exact test), Q value = 1

Table S440. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
TAF5 MUTATED	0	4	0	0	0	0
TAF5 WILD-TYPE	9	13	7	12	6	5

'SARM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0301 (Fisher's exact test), Q value = 1

Table S441. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
SARM1 MUTATED	4	0	0	3	0
SARM1 WILD-TYPE	17	19	8	5	6

Figure S31. Get High-res Image Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'SARM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.435 (Fisher's exact test), Q value = 1

Table S442. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
SARM1 MUTATED	0	1	3	2	0
SARM1 WILD-TYPE	13	7	11	12	7

'SARM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.275 (Fisher's exact test), Q value = 1

Table S443. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
SARM1 MUTATED	2	1	3	0
SARM1 WILD-TYPE	15	7	11	16

'SARM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0285 (Fisher's exact test), Q value = 1

Table S444. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
SARM1 MUTATED	1	3	2	0
SARM1 WILD-TYPE	15	13	3	18

Figure S32. Get High-res Image Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'SARM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 1

Table S445. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
SARM1 MUTATED	1	3	2
SARM1 WILD-TYPE	25	9	16

'SARM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.754 (Fisher's exact test), Q value = 1

Table S446. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
SARM1 MUTATED	2	3	0	1	0
SARM1 WILD-TYPE	11	16	8	13	2

'SARM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.046 (Fisher's exact test), Q value = 1

Table S447. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
SARM1 MUTATED	1	4	1
SARM1 WILD-TYPE	26	9	15

Figure S33. Get High-res Image Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'SARM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.917 (Fisher's exact test), Q value = 1

Table S448. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
SARM1 MUTATED	1	2	0	1	1	1
SARM1 WILD-TYPE	8	15	7	11	5	4

'PRSS27 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.797 (Fisher's exact test), Q value = 1

Table S449. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
PRSS27 MUTATED	1	1	1	0	0
PRSS27 WILD-TYPE	20	18	7	8	6

'PRSS27 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.909 (Fisher's exact test), Q value = 1

Table S450. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
PRSS27 MUTATED	0	1	1	1	0
PRSS27 WILD-TYPE	13	7	13	13	7

'PRSS27 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S451. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
PRSS27 MUTATED	1	1	1	0
PRSS27 WILD-TYPE	16	7	13	16

'PRSS27 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.108 (Fisher's exact test), Q value = 1

Table S452. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
PRSS27 MUTATED	0	2	1	0
PRSS27 WILD-TYPE	16	14	4	18

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S453. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
PRSS27 MUTATED	1	2	0
PRSS27 WILD-TYPE	25	10	18

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S454. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
PRSS27 MUTATED	1	1	0	1	0
PRSS27 WILD-TYPE	12	18	8	13	2

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.206 (Fisher's exact test), Q value = 1

Table S455. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
PRSS27 MUTATED	1	2	0
PRSS27 WILD-TYPE	26	11	16

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S456. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
PRSS27 MUTATED	1	1	0	1	0	0
PRSS27 WILD-TYPE	8	16	7	11	6	5

'TMEM189 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.162 (Fisher's exact test), Q value = 1

Table S457. Gene #58: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
TMEM189 MUTATED	2	0	0	2	0
TMEM189 WILD-TYPE	19	19	8	6	6

'NOXA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 1

Table S458. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
NOXA1 MUTATED	3	0	2	0	0
NOXA1 WILD-TYPE	18	19	6	8	6

'NOXA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 1

Table S459. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
NOXA1 MUTATED	2	0	1	0	0
NOXA1 WILD-TYPE	11	8	13	14	7

'NOXA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 1

Table S460. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
NOXA1 MUTATED	2	1	0	0
NOXA1 WILD-TYPE	15	7	14	16

'NOXA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S461. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
NOXA1 MUTATED	2	1	0	0
NOXA1 WILD-TYPE	14	15	5	18

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S462. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
NOXA1 MUTATED	3	0	0
NOXA1 WILD-TYPE	23	12	18

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.341 (Fisher's exact test), Q value = 1

Table S463. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
NOXA1 MUTATED	1	0	0	2	0
NOXA1 WILD-TYPE	12	19	8	12	2

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S464. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
NOXA1 MUTATED	3	0	0
NOXA1 WILD-TYPE	24	13	16

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.328 (Fisher's exact test), Q value = 1

Table S465. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
NOXA1 MUTATED	1	0	0	2	0	0
NOXA1 WILD-TYPE	8	17	7	10	6	5

'LRP11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0406 (Fisher's exact test), Q value = 1

Table S466. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
LRP11 MUTATED	0	2	1	3	0
LRP11 WILD-TYPE	21	17	7	5	6

Figure S34. Get High-res Image Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'LRP11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0727 (Fisher's exact test), Q value = 1

Table S467. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
LRP11 MUTATED	1	0	4	0	0
LRP11 WILD-TYPE	12	8	10	14	7

'LRP11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S468. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
LRP11 MUTATED	1	1	2	1
LRP11 WILD-TYPE	16	7	12	15

'LRP11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.541 (Fisher's exact test), Q value = 1

Table S469. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
LRP11 MUTATED	1	3	0	1
LRP11 WILD-TYPE	15	13	5	17

'LRP11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S470. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
LRP11 MUTATED	2	2	1
LRP11 WILD-TYPE	24	10	17

'LRP11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S471. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
LRP11 MUTATED	1	2	0	2	0
LRP11 WILD-TYPE	12	17	8	12	2

'LRP11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S472. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
LRP11 MUTATED	2	2	1
LRP11 WILD-TYPE	25	11	15

'LRP11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.95 (Fisher's exact test), Q value = 1

Table S473. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
LRP11 MUTATED	1	2	0	2	0	0
LRP11 WILD-TYPE	8	15	7	10	6	5

'RNF149 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.376 (Fisher's exact test), Q value = 1

Table S474. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
RNF149 MUTATED	0	2	1	1	0
RNF149 WILD-TYPE	21	17	7	7	6

'RNF149 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0356 (Fisher's exact test), Q value = 1

Table S475. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
RNF149 MUTATED	0	0	2	0	2
RNF149 WILD-TYPE	13	8	12	14	5

Figure S35. Get High-res Image Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'RNF149 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 1

Table S476. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
RNF149 MUTATED	0	1	2	1
RNF149 WILD-TYPE	17	7	12	15

'RNF149 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.616 (Fisher's exact test), Q value = 1

Table S477. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
RNF149 MUTATED	0	2	0	2
RNF149 WILD-TYPE	16	14	5	16

'RNF149 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S478. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
RNF149 MUTATED	1	2	1
RNF149 WILD-TYPE	25	10	17

'RNF149 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S479. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
RNF149 MUTATED	0	3	1	0	0
RNF149 WILD-TYPE	13	16	7	14	2

'RNF149 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S480. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
RNF149 MUTATED	1	2	1
RNF149 WILD-TYPE	26	11	15

'RNF149 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S481. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
RNF149 MUTATED	0	3	1	0	0	0
RNF149 WILD-TYPE	9	14	6	12	6	5

'DMKN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S482. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
DMKN MUTATED	1	1	0	1	0
DMKN WILD-TYPE	20	18	8	7	6

'DMKN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.292 (Fisher's exact test), Q value = 1

Table S483. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
DMKN MUTATED	0	1	2	0	0
DMKN WILD-TYPE	13	7	12	14	7

'DMKN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.611 (Fisher's exact test), Q value = 1

Table S484. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
DMKN MUTATED	1	1	1	0
DMKN WILD-TYPE	16	7	13	16

'DMKN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S485. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
DMKN MUTATED	1	2	0	0
DMKN WILD-TYPE	15	14	5	18

'DMKN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00831 (Fisher's exact test), Q value = 1

Table S486. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
DMKN MUTATED	0	3	0
DMKN WILD-TYPE	26	9	18

Figure S36. Get High-res Image Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'DMKN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.56 (Fisher's exact test), Q value = 1

Table S487. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
DMKN MUTATED	0	1	0	2	0
DMKN WILD-TYPE	13	18	8	12	2

'DMKN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0101 (Fisher's exact test), Q value = 1

Table S488. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
DMKN MUTATED	0	3	0
DMKN WILD-TYPE	27	10	16

Figure S37. Get High-res Image Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'DMKN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S489. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
DMKN MUTATED	0	1	0	1	1	0
DMKN WILD-TYPE	9	16	7	11	5	5

'FANK1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S490. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
FANK1 MUTATED	2	1	1	0	0
FANK1 WILD-TYPE	19	18	7	8	6

'FANK1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S491. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
FANK1 MUTATED	0	1	0	1	1
FANK1 WILD-TYPE	13	7	14	13	6

'FANK1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S492. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
FANK1 MUTATED	1	1	0	1
FANK1 WILD-TYPE	16	7	14	15

'FANK1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.328 (Fisher's exact test), Q value = 1

Table S493. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
FANK1 MUTATED	1	0	1	1
FANK1 WILD-TYPE	15	16	4	17

'FANK1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S494. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
FANK1 MUTATED	1	1	1
FANK1 WILD-TYPE	25	11	17

'FANK1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.227 (Fisher's exact test), Q value = 1

Table S495. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
FANK1 MUTATED	0	0	1	2	0
FANK1 WILD-TYPE	13	19	7	12	2

'FANK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S496. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
FANK1 MUTATED	1	1	1
FANK1 WILD-TYPE	26	12	15

'FANK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S497. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
FANK1 MUTATED	0	0	0	1	1	1
FANK1 WILD-TYPE	9	17	7	11	5	4

'MUC5B MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S498. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
MUC5B MUTATED	7	6	3	3	2
MUC5B WILD-TYPE	14	13	5	5	4

'MUC5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.572 (Fisher's exact test), Q value = 1

Table S499. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
MUC5B MUTATED	3	3	6	4	4
MUC5B WILD-TYPE	10	5	8	10	3

'MUC5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S500. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
MUC5B MUTATED	5	3	7	5
MUC5B WILD-TYPE	12	5	7	11

'MUC5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.731 (Fisher's exact test), Q value = 1

Table S501. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
MUC5B MUTATED	4	7	2	7
MUC5B WILD-TYPE	12	9	3	11

'MUC5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S502. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
MUC5B MUTATED	8	5	7
MUC5B WILD-TYPE	18	7	11

'MUC5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S503. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
MUC5B MUTATED	3	7	4	6	0
MUC5B WILD-TYPE	10	12	4	8	2

'MUC5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S504. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
MUC5B MUTATED	8	6	6
MUC5B WILD-TYPE	19	7	10

'MUC5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.846 (Fisher's exact test), Q value = 1

Table S505. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
MUC5B MUTATED	3	6	2	6	1	2
MUC5B WILD-TYPE	6	11	5	6	5	3

'PABPC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.415 (Fisher's exact test), Q value = 1

Table S506. Gene #65: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
PABPC1 MUTATED	1	1	2	0	0
PABPC1 WILD-TYPE	20	18	6	8	6

'GLTPD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0714 (Fisher's exact test), Q value = 1

Table S507. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
GLTPD2 MUTATED	1	1	0	3	1
GLTPD2 WILD-TYPE	20	18	8	5	5

'GLTPD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S508. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
GLTPD2 MUTATED	1	0	2	2	1
GLTPD2 WILD-TYPE	12	8	12	12	6

'GLTPD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S509. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
GLTPD2 MUTATED	2	0	2	2
GLTPD2 WILD-TYPE	15	8	12	14

'GLTPD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S510. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
GLTPD2 MUTATED	1	3	1	1
GLTPD2 WILD-TYPE	15	13	4	17

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S511. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
GLTPD2 MUTATED	3	2	1
GLTPD2 WILD-TYPE	23	10	17

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S512. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
GLTPD2 MUTATED	2	1	0	3	0
GLTPD2 WILD-TYPE	11	18	8	11	2

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.858 (Fisher's exact test), Q value = 1

Table S513. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
GLTPD2 MUTATED	3	2	1
GLTPD2 WILD-TYPE	24	11	15

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S514. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
GLTPD2 MUTATED	1	1	1	3	0	0
GLTPD2 WILD-TYPE	8	16	6	9	6	5

'MEN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0955 (Fisher's exact test), Q value = 1

Table S515. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
MEN1 MUTATED	0	1	1	2	0
MEN1 WILD-TYPE	21	18	7	6	6

'MEN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0433 (Fisher's exact test), Q value = 1

Table S516. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
MEN1 MUTATED	0	1	4	0	0
MEN1 WILD-TYPE	13	7	10	14	7

Figure S38. Get High-res Image Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'MEN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0127 (Fisher's exact test), Q value = 1

Table S517. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
MEN1 MUTATED	0	1	4	0
MEN1 WILD-TYPE	17	7	10	16

Figure S39. Get High-res Image Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'MEN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00613 (Fisher's exact test), Q value = 1

Table S518. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
MEN1 MUTATED	0	5	0	0
MEN1 WILD-TYPE	16	11	5	18

Figure S40. Get High-res Image Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'MEN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 1

Table S519. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
MEN1 MUTATED	4	1	0
MEN1 WILD-TYPE	22	11	18

'MEN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0387 (Fisher's exact test), Q value = 1

Table S520. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
MEN1 MUTATED	4	0	0	1	0
MEN1 WILD-TYPE	9	19	8	13	2

Figure S41. Get High-res Image Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'MEN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S521. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
MEN1 MUTATED	4	1	0
MEN1 WILD-TYPE	23	12	16

'MEN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00889 (Fisher's exact test), Q value = 1

Table S522. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
MEN1 MUTATED	4	0	0	1	0	0
MEN1 WILD-TYPE	5	17	7	11	6	5

Figure S42. Get High-res Image Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'SRPX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S523. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
SRPX MUTATED	1	2	0	0	0
SRPX WILD-TYPE	20	17	8	8	6

'SRPX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S524. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
SRPX MUTATED	0	2	0	1	0
SRPX WILD-TYPE	13	6	14	13	7

'SRPX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S525. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
SRPX MUTATED	0	1	1	1
SRPX WILD-TYPE	17	7	13	15

'SRPX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S526. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
SRPX MUTATED	1	1	0	1
SRPX WILD-TYPE	15	15	5	17

'SRPX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.789 (Fisher's exact test), Q value = 1

Table S527. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
SRPX MUTATED	1	1	1
SRPX WILD-TYPE	25	11	17

'SRPX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.789 (Fisher's exact test), Q value = 1

Table S528. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
SRPX MUTATED	1	2	0	0	0
SRPX WILD-TYPE	12	17	8	14	2

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S529. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
SRPX MUTATED	1	1	1
SRPX WILD-TYPE	26	12	15

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S530. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
SRPX MUTATED	1	2	0	0	0	0
SRPX WILD-TYPE	8	15	7	12	6	5

'MAP1S MUTATION STATUS' versus 'CN_CNMF'

P value = 0.276 (Fisher's exact test), Q value = 1

Table S531. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
MAP1S MUTATED	0	2	1	1	1
MAP1S WILD-TYPE	21	17	7	7	5

'MAP1S MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S532. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
MAP1S MUTATED	1	1	0	3	0
MAP1S WILD-TYPE	12	7	14	11	7

'MAP1S MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S533. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
MAP1S MUTATED	1	1	0	3
MAP1S WILD-TYPE	16	7	14	13

'MAP1S MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S534. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
MAP1S MUTATED	2	1	0	2
MAP1S WILD-TYPE	14	15	5	16

'MAP1S MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S535. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
MAP1S MUTATED	2	1	2
MAP1S WILD-TYPE	24	11	16

'MAP1S MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S536. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
MAP1S MUTATED	2	2	0	1	0
MAP1S WILD-TYPE	11	17	8	13	2

'MAP1S MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S537. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
MAP1S MUTATED	2	1	2
MAP1S WILD-TYPE	25	12	14

'MAP1S MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S538. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
MAP1S MUTATED	1	2	1	1	0	0
MAP1S WILD-TYPE	8	15	6	11	6	5

'SCRT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S539. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
SCRT1 MUTATED	1	1	0	1	0
SCRT1 WILD-TYPE	20	18	8	7	6

'SCRT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 1

Table S540. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
SCRT1 MUTATED	2	0	0	1	0
SCRT1 WILD-TYPE	11	8	14	13	7

'SCRT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S541. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
SCRT1 MUTATED	2	0	1	0
SCRT1 WILD-TYPE	15	8	13	16

'SCRT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.639 (Fisher's exact test), Q value = 1

Table S542. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
SCRT1 MUTATED	2	0	0	1
SCRT1 WILD-TYPE	14	16	5	17

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S543. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
SCRT1 MUTATED	2	1	0
SCRT1 WILD-TYPE	24	11	18

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.71 (Fisher's exact test), Q value = 1

Table S544. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
SCRT1 MUTATED	0	1	1	1	0
SCRT1 WILD-TYPE	13	18	7	13	2

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.592 (Fisher's exact test), Q value = 1

Table S545. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
SCRT1 MUTATED	2	1	0
SCRT1 WILD-TYPE	25	12	16

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S546. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
SCRT1 MUTATED	0	1	1	1	0	0
SCRT1 WILD-TYPE	9	16	6	11	6	5

'OBSCN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.657 (Fisher's exact test), Q value = 1

Table S547. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
OBSCN MUTATED	9	6	1	2	2
OBSCN WILD-TYPE	12	13	7	6	4

'OBSCN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 1

Table S548. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
OBSCN MUTATED	4	5	2	5	2
OBSCN WILD-TYPE	9	3	12	9	5

'OBSCN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.458 (Fisher's exact test), Q value = 1

Table S549. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
OBSCN MUTATED	7	2	6	3
OBSCN WILD-TYPE	10	6	8	13

'OBSCN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S550. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
OBSCN MUTATED	5	5	3	5
OBSCN WILD-TYPE	11	11	2	13

'OBSCN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0945 (Fisher's exact test), Q value = 1

Table S551. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
OBSCN MUTATED	7	7	4
OBSCN WILD-TYPE	19	5	14

'OBSCN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S552. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
OBSCN MUTATED	3	6	3	6	0
OBSCN WILD-TYPE	10	13	5	8	2

'OBSCN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.196 (Fisher's exact test), Q value = 1

Table S553. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
OBSCN MUTATED	7	7	4
OBSCN WILD-TYPE	20	6	12

'OBSCN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.73 (Fisher's exact test), Q value = 1

Table S554. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
OBSCN MUTATED	2	4	2	6	2	2
OBSCN WILD-TYPE	7	13	5	6	4	3

'IER5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.369 (Fisher's exact test), Q value = 1

Table S555. Gene #72: 'IER5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
IER5 MUTATED	3	0	0	0	0
IER5 WILD-TYPE	18	19	8	8	6

'TNIP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S556. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
TNIP2 MUTATED	2	1	0	1	1
TNIP2 WILD-TYPE	19	18	8	7	5

'TNIP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S557. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
TNIP2 MUTATED	1	1	2	0	0
TNIP2 WILD-TYPE	12	7	12	14	7

'TNIP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.735 (Fisher's exact test), Q value = 1

Table S558. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
TNIP2 MUTATED	1	0	2	1
TNIP2 WILD-TYPE	16	8	12	15

'TNIP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S559. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
TNIP2 MUTATED	1	2	0	1
TNIP2 WILD-TYPE	15	14	5	17

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S560. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
TNIP2 MUTATED	2	1	1
TNIP2 WILD-TYPE	24	11	17

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.402 (Fisher's exact test), Q value = 1

Table S561. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
TNIP2 MUTATED	1	0	1	2	0
TNIP2 WILD-TYPE	12	19	7	12	2

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S562. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
TNIP2 MUTATED	2	1	1
TNIP2 WILD-TYPE	25	12	15

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.235 (Fisher's exact test), Q value = 1

Table S563. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
TNIP2 MUTATED	1	0	0	2	0	1
TNIP2 WILD-TYPE	8	17	7	10	6	4

'NOTCH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.304 (Fisher's exact test), Q value = 1

Table S564. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
NOTCH2 MUTATED	4	1	0	2	0
NOTCH2 WILD-TYPE	17	18	8	6	6

'NOTCH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.798 (Fisher's exact test), Q value = 1

Table S565. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
NOTCH2 MUTATED	1	0	2	2	0
NOTCH2 WILD-TYPE	12	8	12	12	7

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S566. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
NOTCH2 MUTATED	3	1	1	0
NOTCH2 WILD-TYPE	14	7	13	16

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0338 (Fisher's exact test), Q value = 1

Table S567. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
NOTCH2 MUTATED	1	2	2	0
NOTCH2 WILD-TYPE	15	14	3	18

Figure S43. Get High-res Image Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00835 (Fisher's exact test), Q value = 1

Table S568. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
NOTCH2 MUTATED	1	4	0
NOTCH2 WILD-TYPE	25	8	18

Figure S44. Get High-res Image Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S569. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
NOTCH2 MUTATED	0	2	0	3	0
NOTCH2 WILD-TYPE	13	17	8	11	2

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00893 (Fisher's exact test), Q value = 1

Table S570. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
NOTCH2 MUTATED	1	4	0
NOTCH2 WILD-TYPE	26	9	16

Figure S45. Get High-res Image Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.325 (Fisher's exact test), Q value = 1

Table S571. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
NOTCH2 MUTATED	0	1	0	3	1	0
NOTCH2 WILD-TYPE	9	16	7	9	5	5

'RASIP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.63 (Fisher's exact test), Q value = 1

Table S572. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
RASIP1 MUTATED	3	2	2	0	0
RASIP1 WILD-TYPE	18	17	6	8	6

'RASIP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S573. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
RASIP1 MUTATED	2	2	2	1	0
RASIP1 WILD-TYPE	11	6	12	13	7

'RASIP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0391 (Fisher's exact test), Q value = 1

Table S574. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
RASIP1 MUTATED	3	3	1	0
RASIP1 WILD-TYPE	14	5	13	16

Figure S46. Get High-res Image Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'RASIP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.159 (Fisher's exact test), Q value = 1

Table S575. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
RASIP1 MUTATED	3	3	1	0
RASIP1 WILD-TYPE	13	13	4	18

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.022 (Fisher's exact test), Q value = 1

Table S576. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
RASIP1 MUTATED	3	4	0
RASIP1 WILD-TYPE	23	8	18

Figure S47. Get High-res Image Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.686 (Fisher's exact test), Q value = 1

Table S577. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
RASIP1 MUTATED	1	3	0	3	0
RASIP1 WILD-TYPE	12	16	8	11	2

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0377 (Fisher's exact test), Q value = 1

Table S578. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
RASIP1 MUTATED	3	4	0
RASIP1 WILD-TYPE	24	9	16

Figure S48. Get High-res Image Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S579. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
RASIP1 MUTATED	1	2	0	3	1	0
RASIP1 WILD-TYPE	8	15	7	9	5	5

'NMU MUTATION STATUS' versus 'CN_CNMF'

P value = 0.821 (Fisher's exact test), Q value = 1

Table S580. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
NMU MUTATED	1	2	1	0	0
NMU WILD-TYPE	20	17	7	8	6

'NMU MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S581. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
NMU MUTATED	1	1	1	1	0
NMU WILD-TYPE	12	7	13	13	7

'NMU MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0485 (Fisher's exact test), Q value = 1

Table S582. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
NMU MUTATED	0	2	0	1
NMU WILD-TYPE	17	6	14	15

Figure S49. Get High-res Image Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'NMU MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.639 (Fisher's exact test), Q value = 1

Table S583. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
NMU MUTATED	0	2	0	1
NMU WILD-TYPE	16	14	5	17

'NMU MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S584. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
NMU MUTATED	2	1	1
NMU WILD-TYPE	24	11	17

'NMU MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.506 (Fisher's exact test), Q value = 1

Table S585. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
NMU MUTATED	2	2	0	0	0
NMU WILD-TYPE	11	17	8	14	2

'NMU MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S586. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
NMU MUTATED	2	1	1
NMU WILD-TYPE	25	12	15

'NMU MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S587. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
NMU MUTATED	2	2	0	0	0	0
NMU WILD-TYPE	7	15	7	12	6	5

'VARS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S588. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
VARS MUTATED	1	2	1	2	0
VARS WILD-TYPE	20	17	7	6	6

'VARS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.437 (Fisher's exact test), Q value = 1

Table S589. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
VARS MUTATED	0	1	3	2	0
VARS WILD-TYPE	13	7	11	12	7

'VARS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 1

Table S590. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
VARS MUTATED	1	0	4	1
VARS WILD-TYPE	16	8	10	15

'VARS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0818 (Fisher's exact test), Q value = 1

Table S591. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
VARS MUTATED	0	4	1	1
VARS WILD-TYPE	16	12	4	17

'VARS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S592. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
VARS MUTATED	2	2	2
VARS WILD-TYPE	24	10	16

'VARS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S593. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
VARS MUTATED	2	2	0	2	0
VARS WILD-TYPE	11	17	8	12	2

'VARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S594. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
VARS MUTATED	2	3	1
VARS WILD-TYPE	25	10	15

'VARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S595. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
VARS MUTATED	2	2	0	2	0	0
VARS WILD-TYPE	7	15	7	10	6	5

'SHOX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 1

Table S596. Gene #78: 'SHOX2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
SHOX2 MUTATED	2	0	0	0	1
SHOX2 WILD-TYPE	19	19	8	8	5

'HSD17B1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S597. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
HSD17B1 MUTATED	2	2	0	0	0
HSD17B1 WILD-TYPE	19	17	8	8	6

'HSD17B1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.108 (Fisher's exact test), Q value = 1

Table S598. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
HSD17B1 MUTATED	0	0	0	3	1
HSD17B1 WILD-TYPE	13	8	14	11	6

'HSD17B1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S599. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
HSD17B1 MUTATED	2	0	1	1
HSD17B1 WILD-TYPE	15	8	13	15

'HSD17B1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0127 (Fisher's exact test), Q value = 1

Table S600. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
HSD17B1 MUTATED	0	0	2	2
HSD17B1 WILD-TYPE	16	16	3	16

Figure S50. Get High-res Image Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S601. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
HSD17B1 MUTATED	2	1	1
HSD17B1 WILD-TYPE	24	11	17

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S602. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
HSD17B1 MUTATED	1	1	0	2	0
HSD17B1 WILD-TYPE	12	18	8	12	2

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S603. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
HSD17B1 MUTATED	2	1	1
HSD17B1 WILD-TYPE	25	12	15

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S604. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
HSD17B1 MUTATED	0	1	1	1	1	0
HSD17B1 WILD-TYPE	9	16	6	11	5	5

'COQ2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S605. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
COQ2 MUTATED	1	1	0	2	1
COQ2 WILD-TYPE	20	18	8	6	5

'COQ2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S606. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
COQ2 MUTATED	0	1	1	1	1
COQ2 WILD-TYPE	13	7	13	13	6

'COQ2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.361 (Fisher's exact test), Q value = 1

Table S607. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
COQ2 MUTATED	0	1	2	1
COQ2 WILD-TYPE	17	7	12	15

'COQ2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.616 (Fisher's exact test), Q value = 1

Table S608. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
COQ2 MUTATED	0	2	0	2
COQ2 WILD-TYPE	16	14	5	16

'COQ2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S609. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
COQ2 MUTATED	2	1	1
COQ2 WILD-TYPE	24	11	17

'COQ2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.669 (Fisher's exact test), Q value = 1

Table S610. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
COQ2 MUTATED	1	2	1	0	0
COQ2 WILD-TYPE	12	17	7	14	2

'COQ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S611. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
COQ2 MUTATED	2	1	1
COQ2 WILD-TYPE	25	12	15

'COQ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S612. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
COQ2 MUTATED	1	2	1	0	0	0
COQ2 WILD-TYPE	8	15	6	12	6	5

'KNDC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S613. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
KNDC1 MUTATED	2	4	2	1	1
KNDC1 WILD-TYPE	19	15	6	7	5

'KNDC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 1

Table S614. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
KNDC1 MUTATED	0	2	2	2	3
KNDC1 WILD-TYPE	13	6	12	12	4

'KNDC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S615. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
KNDC1 MUTATED	1	3	1	4
KNDC1 WILD-TYPE	16	5	13	12

'KNDC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.372 (Fisher's exact test), Q value = 1

Table S616. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
KNDC1 MUTATED	1	2	1	5
KNDC1 WILD-TYPE	15	14	4	13

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.288 (Fisher's exact test), Q value = 1

Table S617. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
KNDC1 MUTATED	2	3	4
KNDC1 WILD-TYPE	24	9	14

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.357 (Fisher's exact test), Q value = 1

Table S618. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
KNDC1 MUTATED	1	4	3	1	0
KNDC1 WILD-TYPE	12	15	5	13	2

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.228 (Fisher's exact test), Q value = 1

Table S619. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
KNDC1 MUTATED	2	3	4
KNDC1 WILD-TYPE	25	10	12

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.749 (Fisher's exact test), Q value = 1

Table S620. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
KNDC1 MUTATED	1	3	1	1	1	2
KNDC1 WILD-TYPE	8	14	6	11	5	3

'AR MUTATION STATUS' versus 'CN_CNMF'

P value = 0.32 (Fisher's exact test), Q value = 1

Table S621. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
AR MUTATED	2	0	0	1	1
AR WILD-TYPE	19	19	8	7	5

'AR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 1

Table S622. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
AR MUTATED	2	0	1	0	0
AR WILD-TYPE	11	8	13	14	7

'AR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S623. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
AR MUTATED	2	0	1	0
AR WILD-TYPE	15	8	13	16

'AR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S624. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
AR MUTATED	2	1	0	0
AR WILD-TYPE	14	15	5	18

'AR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S625. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
AR MUTATED	2	1	0
AR WILD-TYPE	24	11	18

'AR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S626. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
AR MUTATED	1	1	0	1	0
AR WILD-TYPE	12	18	8	13	2

'AR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.596 (Fisher's exact test), Q value = 1

Table S627. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
AR MUTATED	2	1	0
AR WILD-TYPE	25	12	16

'AR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S628. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
AR MUTATED	1	1	0	1	0	0
AR WILD-TYPE	8	16	7	11	6	5

'KCTD3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.414 (Fisher's exact test), Q value = 1

Table S629. Gene #83: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
KCTD3 MUTATED	1	1	0	2	0
KCTD3 WILD-TYPE	20	18	8	6	6

'FZD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S630. Gene #84: 'FZD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
FZD1 MUTATED	1	0	1	1	0
FZD1 WILD-TYPE	20	19	7	7	6

'ZC3H12D MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0033 (Fisher's exact test), Q value = 1

Table S631. Gene #85: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
ZC3H12D MUTATED	0	0	0	3	0
ZC3H12D WILD-TYPE	21	19	8	5	6

Figure S51. Get High-res Image Gene #85: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'KRTAP5-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.362 (Fisher's exact test), Q value = 1

Table S632. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
KRTAP5-5 MUTATED	1	1	1	2	0
KRTAP5-5 WILD-TYPE	20	18	7	6	6

'KRTAP5-5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S633. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
KRTAP5-5 MUTATED	1	0	1	1	0
KRTAP5-5 WILD-TYPE	12	8	13	13	7

'KRTAP5-5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 1

Table S634. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
KRTAP5-5 MUTATED	2	1	0	0
KRTAP5-5 WILD-TYPE	15	7	14	16

'KRTAP5-5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.216 (Fisher's exact test), Q value = 1

Table S635. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
KRTAP5-5 MUTATED	1	1	1	0
KRTAP5-5 WILD-TYPE	15	15	4	18

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S636. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
KRTAP5-5 MUTATED	2	1	0
KRTAP5-5 WILD-TYPE	24	11	18

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.18 (Fisher's exact test), Q value = 1

Table S637. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
KRTAP5-5 MUTATED	0	1	0	1	1
KRTAP5-5 WILD-TYPE	13	18	8	13	1

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S638. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
KRTAP5-5 MUTATED	2	1	0
KRTAP5-5 WILD-TYPE	25	12	16

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.056 (Fisher's exact test), Q value = 1

Table S639. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
KRTAP5-5 MUTATED	0	0	0	1	2	0
KRTAP5-5 WILD-TYPE	9	17	7	11	4	5

'AKAP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0745 (Fisher's exact test), Q value = 1

Table S640. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
AKAP2 MUTATED	1	0	0	2	1
AKAP2 WILD-TYPE	20	19	8	6	5

'AKAP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.475 (Fisher's exact test), Q value = 1

Table S641. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
AKAP2 MUTATED	0	0	2	2	0
AKAP2 WILD-TYPE	13	8	12	12	7

'AKAP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.738 (Fisher's exact test), Q value = 1

Table S642. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
AKAP2 MUTATED	1	0	2	1
AKAP2 WILD-TYPE	16	8	12	15

'AKAP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S643. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
AKAP2 MUTATED	0	2	1	1
AKAP2 WILD-TYPE	16	14	4	17

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S644. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
AKAP2 MUTATED	1	1	2
AKAP2 WILD-TYPE	25	11	16

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S645. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
AKAP2 MUTATED	1	3	0	0	0
AKAP2 WILD-TYPE	12	16	8	14	2

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.341 (Fisher's exact test), Q value = 1

Table S646. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
AKAP2 MUTATED	1	2	1
AKAP2 WILD-TYPE	26	11	15

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.647 (Fisher's exact test), Q value = 1

Table S647. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
AKAP2 MUTATED	1	2	0	0	1	0
AKAP2 WILD-TYPE	8	15	7	12	5	5

'KBTBD13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S648. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
KBTBD13 MUTATED	5	3	0	1	0
KBTBD13 WILD-TYPE	16	16	8	7	6

'KBTBD13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 1

Table S649. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
KBTBD13 MUTATED	3	1	0	2	3
KBTBD13 WILD-TYPE	10	7	14	12	4

'KBTBD13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S650. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
KBTBD13 MUTATED	4	1	1	3
KBTBD13 WILD-TYPE	13	7	13	13

'KBTBD13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.135 (Fisher's exact test), Q value = 1

Table S651. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
KBTBD13 MUTATED	4	0	1	4
KBTBD13 WILD-TYPE	12	16	4	14

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S652. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
KBTBD13 MUTATED	4	2	3
KBTBD13 WILD-TYPE	22	10	15

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.358 (Fisher's exact test), Q value = 1

Table S653. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
KBTBD13 MUTATED	0	4	2	3	0
KBTBD13 WILD-TYPE	13	15	6	11	2

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S654. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
KBTBD13 MUTATED	4	2	3
KBTBD13 WILD-TYPE	23	11	13

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S655. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
KBTBD13 MUTATED	0	4	1	2	1	1
KBTBD13 WILD-TYPE	9	13	6	10	5	4

'SPIRE2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S656. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
SPIRE2 MUTATED	0	1	1	1	0
SPIRE2 WILD-TYPE	21	18	7	7	6

'SPIRE2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0267 (Fisher's exact test), Q value = 1

Table S657. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
SPIRE2 MUTATED	1	0	0	0	2
SPIRE2 WILD-TYPE	12	8	14	14	5

Figure S52. Get High-res Image Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'SPIRE2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S658. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
SPIRE2 MUTATED	1	0	1	1
SPIRE2 WILD-TYPE	16	8	13	15

'SPIRE2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S659. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
SPIRE2 MUTATED	1	0	0	2
SPIRE2 WILD-TYPE	15	16	5	16

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S660. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
SPIRE2 MUTATED	2	0	1
SPIRE2 WILD-TYPE	24	12	17

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S661. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
SPIRE2 MUTATED	0	1	1	1	0
SPIRE2 WILD-TYPE	13	18	7	13	2

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S662. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
SPIRE2 MUTATED	2	0	1
SPIRE2 WILD-TYPE	25	13	15

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S663. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
SPIRE2 MUTATED	0	1	1	1	0	0
SPIRE2 WILD-TYPE	9	16	6	11	6	5

'NPTX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.337 (Fisher's exact test), Q value = 1

Table S664. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
NPTX1 MUTATED	2	0	0	0	1
NPTX1 WILD-TYPE	19	19	8	8	5

'NPTX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S665. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
NPTX1 MUTATED	1	0	1	1	0
NPTX1 WILD-TYPE	12	8	13	13	7

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S666. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
NPTX1 MUTATED	1	0	1	1
NPTX1 WILD-TYPE	16	8	13	15

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S667. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
NPTX1 MUTATED	1	0	0	2
NPTX1 WILD-TYPE	15	16	5	16

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S668. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
NPTX1 MUTATED	1	0	2
NPTX1 WILD-TYPE	25	12	16

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S669. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
NPTX1 MUTATED	0	1	1	1	0
NPTX1 WILD-TYPE	13	18	7	13	2

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S670. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
NPTX1 MUTATED	1	0	2
NPTX1 WILD-TYPE	26	13	14

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.657 (Fisher's exact test), Q value = 1

Table S671. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
NPTX1 MUTATED	0	1	0	1	0	1
NPTX1 WILD-TYPE	9	16	7	11	6	4

'ADAD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 1

Table S672. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
ADAD2 MUTATED	1	0	1	1	1
ADAD2 WILD-TYPE	20	19	7	7	5

'ADAD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.574 (Fisher's exact test), Q value = 1

Table S673. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
ADAD2 MUTATED	0	0	2	1	1
ADAD2 WILD-TYPE	13	8	12	13	6

'ADAD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.738 (Fisher's exact test), Q value = 1

Table S674. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
ADAD2 MUTATED	1	0	2	1
ADAD2 WILD-TYPE	16	8	12	15

'ADAD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.317 (Fisher's exact test), Q value = 1

Table S675. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
ADAD2 MUTATED	0	2	1	1
ADAD2 WILD-TYPE	16	14	4	17

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0206 (Fisher's exact test), Q value = 1

Table S676. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
ADAD2 MUTATED	0	3	1
ADAD2 WILD-TYPE	26	9	17

Figure S53. Get High-res Image Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S677. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
ADAD2 MUTATED	0	3	0	1	0
ADAD2 WILD-TYPE	13	16	8	13	2

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0196 (Fisher's exact test), Q value = 1

Table S678. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
ADAD2 MUTATED	0	3	1
ADAD2 WILD-TYPE	27	10	15

Figure S54. Get High-res Image Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S679. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
ADAD2 MUTATED	0	2	0	1	1	0
ADAD2 WILD-TYPE	9	15	7	11	5	5

'SEZ6L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S680. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
SEZ6L2 MUTATED	3	3	0	0	2
SEZ6L2 WILD-TYPE	18	16	8	8	4

'SEZ6L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S681. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
SEZ6L2 MUTATED	2	2	1	1	0
SEZ6L2 WILD-TYPE	11	6	13	13	7

'SEZ6L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S682. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
SEZ6L2 MUTATED	2	0	2	2
SEZ6L2 WILD-TYPE	15	8	12	14

'SEZ6L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S683. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
SEZ6L2 MUTATED	2	2	0	2
SEZ6L2 WILD-TYPE	14	14	5	16

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.459 (Fisher's exact test), Q value = 1

Table S684. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
SEZ6L2 MUTATED	4	0	2
SEZ6L2 WILD-TYPE	22	12	16

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S685. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
SEZ6L2 MUTATED	1	1	2	2	0
SEZ6L2 WILD-TYPE	12	18	6	12	2

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S686. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
SEZ6L2 MUTATED	4	0	2
SEZ6L2 WILD-TYPE	23	13	14

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.808 (Fisher's exact test), Q value = 1

Table S687. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
SEZ6L2 MUTATED	1	1	1	2	0	1
SEZ6L2 WILD-TYPE	8	16	6	10	6	4

'NEFH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0362 (Fisher's exact test), Q value = 1

Table S688. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
NEFH MUTATED	6	0	1	0	0
NEFH WILD-TYPE	15	19	7	8	6

Figure S55. Get High-res Image Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'NEFH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 1

Table S689. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
NEFH MUTATED	3	0	0	2	0
NEFH WILD-TYPE	10	8	14	12	7

'NEFH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0236 (Fisher's exact test), Q value = 1

Table S690. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
NEFH MUTATED	4	0	0	0
NEFH WILD-TYPE	13	8	14	16

Figure S56. Get High-res Image Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'NEFH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00825 (Fisher's exact test), Q value = 1

Table S691. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
NEFH MUTATED	2	0	2	0
NEFH WILD-TYPE	14	16	3	18

Figure S57. Get High-res Image Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'NEFH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.168 (Fisher's exact test), Q value = 1

Table S692. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
NEFH MUTATED	3	2	0
NEFH WILD-TYPE	23	10	18

'NEFH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.521 (Fisher's exact test), Q value = 1

Table S693. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
NEFH MUTATED	1	1	0	3	0
NEFH WILD-TYPE	12	18	8	11	2

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S694. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
NEFH MUTATED	3	2	0
NEFH WILD-TYPE	24	11	16

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.158 (Fisher's exact test), Q value = 1

Table S695. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
NEFH MUTATED	1	0	0	3	1	0
NEFH WILD-TYPE	8	17	7	9	5	5

'DLEU7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.568 (Fisher's exact test), Q value = 1

Table S696. Gene #94: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
DLEU7 MUTATED	2	0	1	0	0
DLEU7 WILD-TYPE	19	19	7	8	6

'AMDHD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0266 (Fisher's exact test), Q value = 1

Table S697. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
AMDHD1 MUTATED	3	2	1	5	0
AMDHD1 WILD-TYPE	18	17	7	3	6

Figure S58. Get High-res Image Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'AMDHD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.721 (Fisher's exact test), Q value = 1

Table S698. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
AMDHD1 MUTATED	1	1	4	2	1
AMDHD1 WILD-TYPE	12	7	10	12	6

'AMDHD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.569 (Fisher's exact test), Q value = 1

Table S699. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
AMDHD1 MUTATED	3	2	3	1
AMDHD1 WILD-TYPE	14	6	11	15

'AMDHD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 1

Table S700. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
AMDHD1 MUTATED	1	4	2	2
AMDHD1 WILD-TYPE	15	12	3	16

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 1

Table S701. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
AMDHD1 MUTATED	3	4	2
AMDHD1 WILD-TYPE	23	8	16

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S702. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
AMDHD1 MUTATED	1	4	1	3	0
AMDHD1 WILD-TYPE	12	15	7	11	2

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0625 (Fisher's exact test), Q value = 1

Table S703. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
AMDHD1 MUTATED	3	5	1
AMDHD1 WILD-TYPE	24	8	15

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.954 (Fisher's exact test), Q value = 1

Table S704. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
AMDHD1 MUTATED	1	3	1	3	1	0
AMDHD1 WILD-TYPE	8	14	6	9	5	5

'GLTSCR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.22 (Fisher's exact test), Q value = 1

Table S705. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
GLTSCR2 MUTATED	4	0	0	1	0
GLTSCR2 WILD-TYPE	17	19	8	7	6

'GLTSCR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.806 (Fisher's exact test), Q value = 1

Table S706. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
GLTSCR2 MUTATED	2	0	1	1	0
GLTSCR2 WILD-TYPE	11	8	13	13	7

'GLTSCR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.264 (Fisher's exact test), Q value = 1

Table S707. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
GLTSCR2 MUTATED	3	0	1	0
GLTSCR2 WILD-TYPE	14	8	13	16

'GLTSCR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.197 (Fisher's exact test), Q value = 1

Table S708. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
GLTSCR2 MUTATED	2	1	1	0
GLTSCR2 WILD-TYPE	14	15	4	18

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S709. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
GLTSCR2 MUTATED	2	1	1
GLTSCR2 WILD-TYPE	24	11	17

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.623 (Fisher's exact test), Q value = 1

Table S710. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
GLTSCR2 MUTATED	0	2	0	2	0
GLTSCR2 WILD-TYPE	13	17	8	12	2

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 1

Table S711. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
GLTSCR2 MUTATED	2	2	0
GLTSCR2 WILD-TYPE	25	11	16

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S712. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
GLTSCR2 MUTATED	0	1	0	2	1	0
GLTSCR2 WILD-TYPE	9	16	7	10	5	5

'PLEC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S713. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
PLEC MUTATED	5	6	1	1	0
PLEC WILD-TYPE	16	13	7	7	6

'PLEC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S714. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
PLEC MUTATED	2	2	1	3	2
PLEC WILD-TYPE	11	6	13	11	5

'PLEC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.194 (Fisher's exact test), Q value = 1

Table S715. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
PLEC MUTATED	2	0	5	3
PLEC WILD-TYPE	15	8	9	13

'PLEC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.681 (Fisher's exact test), Q value = 1

Table S716. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
PLEC MUTATED	2	4	0	4
PLEC WILD-TYPE	14	12	5	14

'PLEC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S717. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
PLEC MUTATED	6	2	2
PLEC WILD-TYPE	20	10	16

'PLEC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.604 (Fisher's exact test), Q value = 1

Table S718. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
PLEC MUTATED	4	2	2	2	0
PLEC WILD-TYPE	9	17	6	12	2

'PLEC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S719. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
PLEC MUTATED	7	1	2
PLEC WILD-TYPE	20	12	14

'PLEC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.471 (Fisher's exact test), Q value = 1

Table S720. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
PLEC MUTATED	2	2	3	2	0	1
PLEC WILD-TYPE	7	15	4	10	6	4

'MAP7 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S721. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
MAP7 MUTATED	2	1	0	0	0
MAP7 WILD-TYPE	19	18	8	8	6

'MAP7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S722. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
MAP7 MUTATED	1	0	0	1	1
MAP7 WILD-TYPE	12	8	14	13	6

'MAP7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S723. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
MAP7 MUTATED	1	0	1	1
MAP7 WILD-TYPE	16	8	13	15

'MAP7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S724. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
MAP7 MUTATED	1	0	0	2
MAP7 WILD-TYPE	15	16	5	16

'MAP7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S725. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
MAP7 MUTATED	1	0	2
MAP7 WILD-TYPE	25	12	16

'MAP7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S726. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
MAP7 MUTATED	0	1	1	1	0
MAP7 WILD-TYPE	13	18	7	13	2

'MAP7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S727. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
MAP7 MUTATED	1	0	2
MAP7 WILD-TYPE	26	13	14

'MAP7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.655 (Fisher's exact test), Q value = 1

Table S728. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
MAP7 MUTATED	0	1	0	1	0	1
MAP7 WILD-TYPE	9	16	7	11	6	4

'DSPP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.928 (Fisher's exact test), Q value = 1

Table S729. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
DSPP MUTATED	4	4	1	1	0
DSPP WILD-TYPE	17	15	7	7	6

'DSPP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.064 (Fisher's exact test), Q value = 1

Table S730. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
DSPP MUTATED	1	4	1	3	0
DSPP WILD-TYPE	12	4	13	11	7

'DSPP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S731. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
DSPP MUTATED	3	1	2	3
DSPP WILD-TYPE	14	7	12	13

'DSPP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S732. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
DSPP MUTATED	4	1	1	3
DSPP WILD-TYPE	12	15	4	15

'DSPP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S733. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
DSPP MUTATED	3	3	3
DSPP WILD-TYPE	23	9	15

'DSPP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.574 (Fisher's exact test), Q value = 1

Table S734. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
DSPP MUTATED	1	4	1	2	1
DSPP WILD-TYPE	12	15	7	12	1

'DSPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.313 (Fisher's exact test), Q value = 1

Table S735. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
DSPP MUTATED	3	4	2
DSPP WILD-TYPE	24	9	14

'DSPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.33 (Fisher's exact test), Q value = 1

Table S736. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
DSPP MUTATED	1	3	1	1	3	0
DSPP WILD-TYPE	8	14	6	11	3	5

'CRIPAK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.201 (Fisher's exact test), Q value = 1

Table S737. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
CRIPAK MUTATED	1	4	1	3	1
CRIPAK WILD-TYPE	20	15	7	5	5

'CRIPAK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.928 (Fisher's exact test), Q value = 1

Table S738. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
CRIPAK MUTATED	2	1	2	2	2
CRIPAK WILD-TYPE	11	7	12	12	5

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S739. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
CRIPAK MUTATED	2	0	3	4
CRIPAK WILD-TYPE	15	8	11	12

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S740. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
CRIPAK MUTATED	2	2	1	4
CRIPAK WILD-TYPE	14	14	4	14

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.807 (Fisher's exact test), Q value = 1

Table S741. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
CRIPAK MUTATED	5	1	3
CRIPAK WILD-TYPE	21	11	15

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.359 (Fisher's exact test), Q value = 1

Table S742. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
CRIPAK MUTATED	1	4	3	1	0
CRIPAK WILD-TYPE	12	15	5	13	2

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.719 (Fisher's exact test), Q value = 1

Table S743. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
CRIPAK MUTATED	5	1	3
CRIPAK WILD-TYPE	22	12	13

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.287 (Fisher's exact test), Q value = 1

Table S744. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
CRIPAK MUTATED	1	4	3	1	0	0
CRIPAK WILD-TYPE	8	13	4	11	6	5

'PRKAR1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S745. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
PRKAR1A MUTATED	2	1	1	2	0
PRKAR1A WILD-TYPE	19	18	7	6	6

'PRKAR1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S746. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
PRKAR1A MUTATED	1	1	2	1	1
PRKAR1A WILD-TYPE	12	7	12	13	6

'PRKAR1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 1

Table S747. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
PRKAR1A MUTATED	2	1	3	0
PRKAR1A WILD-TYPE	15	7	11	16

'PRKAR1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S748. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
PRKAR1A MUTATED	1	3	1	1
PRKAR1A WILD-TYPE	15	13	4	17

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0865 (Fisher's exact test), Q value = 1

Table S749. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
PRKAR1A MUTATED	5	1	0
PRKAR1A WILD-TYPE	21	11	18

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.564 (Fisher's exact test), Q value = 1

Table S750. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
PRKAR1A MUTATED	3	1	1	1	0
PRKAR1A WILD-TYPE	10	18	7	13	2

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S751. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
PRKAR1A MUTATED	5	1	0
PRKAR1A WILD-TYPE	22	12	16

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.151 (Fisher's exact test), Q value = 1

Table S752. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
PRKAR1A MUTATED	3	1	1	0	1	0
PRKAR1A WILD-TYPE	6	16	6	12	5	5

'CYP4A22 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 1

Table S753. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
CYP4A22 MUTATED	1	0	2	1	0
CYP4A22 WILD-TYPE	20	19	6	7	6

'CYP4A22 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.622 (Fisher's exact test), Q value = 1

Table S754. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
CYP4A22 MUTATED	1	1	2	0	0
CYP4A22 WILD-TYPE	12	7	12	14	7

'CYP4A22 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.163 (Fisher's exact test), Q value = 1

Table S755. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
CYP4A22 MUTATED	1	2	1	0
CYP4A22 WILD-TYPE	16	6	13	16

'CYP4A22 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S756. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
CYP4A22 MUTATED	2	2	0	0
CYP4A22 WILD-TYPE	14	14	5	18

'CYP4A22 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.246 (Fisher's exact test), Q value = 1

Table S757. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
CYP4A22 MUTATED	2	2	0
CYP4A22 WILD-TYPE	24	10	18

'CYP4A22 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.207 (Fisher's exact test), Q value = 1

Table S758. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
CYP4A22 MUTATED	0	2	0	1	1
CYP4A22 WILD-TYPE	13	17	8	13	1

'CYP4A22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S759. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
CYP4A22 MUTATED	2	2	0
CYP4A22 WILD-TYPE	25	11	16

'CYP4A22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S760. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
CYP4A22 MUTATED	0	2	0	1	1	0
CYP4A22 WILD-TYPE	9	15	7	11	5	5

'NOM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S761. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
NOM1 MUTATED	2	2	1	1	0
NOM1 WILD-TYPE	19	17	7	7	6

'NOM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.233 (Fisher's exact test), Q value = 1

Table S762. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
NOM1 MUTATED	1	1	1	0	2
NOM1 WILD-TYPE	12	7	13	14	5

'NOM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.93 (Fisher's exact test), Q value = 1

Table S763. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
NOM1 MUTATED	2	0	1	2
NOM1 WILD-TYPE	15	8	13	14

'NOM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S764. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
NOM1 MUTATED	2	1	0	2
NOM1 WILD-TYPE	14	15	5	16

'NOM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S765. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
NOM1 MUTATED	2	1	2
NOM1 WILD-TYPE	24	11	16

'NOM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.742 (Fisher's exact test), Q value = 1

Table S766. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
NOM1 MUTATED	2	1	1	1	0
NOM1 WILD-TYPE	11	18	7	13	2

'NOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S767. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
NOM1 MUTATED	2	1	2
NOM1 WILD-TYPE	25	12	14

'NOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.276 (Fisher's exact test), Q value = 1

Table S768. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
NOM1 MUTATED	2	1	0	0	1	1
NOM1 WILD-TYPE	7	16	7	12	5	4

'RNF135 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S769. Gene #104: 'RNF135 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
RNF135 MUTATED	1	2	0	0	0
RNF135 WILD-TYPE	20	17	8	8	6

'C12ORF65 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.371 (Fisher's exact test), Q value = 1

Table S770. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
C12ORF65 MUTATED	3	0	0	0	0
C12ORF65 WILD-TYPE	18	19	8	8	6

'C12ORF65 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0354 (Fisher's exact test), Q value = 1

Table S771. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
C12ORF65 MUTATED	3	0	0	0	0
C12ORF65 WILD-TYPE	10	8	14	14	7

Figure S59. Get High-res Image Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'C12ORF65 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 1

Table S772. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
C12ORF65 MUTATED	3	0	0	0
C12ORF65 WILD-TYPE	14	8	14	16

'C12ORF65 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0623 (Fisher's exact test), Q value = 1

Table S773. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
C12ORF65 MUTATED	3	0	0	0
C12ORF65 WILD-TYPE	13	16	5	18

'C12ORF65 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S774. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
C12ORF65 MUTATED	2	1	0
C12ORF65 WILD-TYPE	24	11	18

'C12ORF65 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S775. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
C12ORF65 MUTATED	0	1	0	2	0
C12ORF65 WILD-TYPE	13	18	8	12	2

'C12ORF65 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S776. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
C12ORF65 MUTATED	2	1	0
C12ORF65 WILD-TYPE	25	12	16

'C12ORF65 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.735 (Fisher's exact test), Q value = 1

Table S777. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
C12ORF65 MUTATED	0	1	0	2	0	0
C12ORF65 WILD-TYPE	9	16	7	10	6	5

'HLA-B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.293 (Fisher's exact test), Q value = 1

Table S778. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
HLA-B MUTATED	1	1	1	2	1
HLA-B WILD-TYPE	20	18	7	6	5

'HLA-B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S779. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
HLA-B MUTATED	2	0	2	2	0
HLA-B WILD-TYPE	11	8	12	12	7

'HLA-B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S780. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
HLA-B MUTATED	2	0	2	2
HLA-B WILD-TYPE	15	8	12	14

'HLA-B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S781. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
HLA-B MUTATED	2	2	0	2
HLA-B WILD-TYPE	14	14	5	16

'HLA-B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.653 (Fisher's exact test), Q value = 1

Table S782. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
HLA-B MUTATED	2	1	3
HLA-B WILD-TYPE	24	11	15

'HLA-B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.274 (Fisher's exact test), Q value = 1

Table S783. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
HLA-B MUTATED	3	3	0	0	0
HLA-B WILD-TYPE	10	16	8	14	2

'HLA-B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.535 (Fisher's exact test), Q value = 1

Table S784. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
HLA-B MUTATED	2	1	3
HLA-B WILD-TYPE	25	12	13

'HLA-B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.319 (Fisher's exact test), Q value = 1

Table S785. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
HLA-B MUTATED	2	3	0	0	0	1
HLA-B WILD-TYPE	7	14	7	12	6	4

'CSGALNACT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S786. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
CSGALNACT2 MUTATED	1	2	0	0	0
CSGALNACT2 WILD-TYPE	20	17	8	8	6

'CSGALNACT2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0256 (Fisher's exact test), Q value = 1

Table S787. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
CSGALNACT2 MUTATED	1	0	0	0	2
CSGALNACT2 WILD-TYPE	12	8	14	14	5

Figure S60. Get High-res Image Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.691 (Fisher's exact test), Q value = 1

Table S788. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
CSGALNACT2 MUTATED	1	0	0	2
CSGALNACT2 WILD-TYPE	16	8	14	14

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S789. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
CSGALNACT2 MUTATED	1	0	0	2
CSGALNACT2 WILD-TYPE	15	16	5	16

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S790. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
CSGALNACT2 MUTATED	1	0	2
CSGALNACT2 WILD-TYPE	25	12	16

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S791. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
CSGALNACT2 MUTATED	0	2	0	1	0
CSGALNACT2 WILD-TYPE	13	17	8	13	2

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S792. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
CSGALNACT2 MUTATED	1	0	2
CSGALNACT2 WILD-TYPE	26	13	14

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.933 (Fisher's exact test), Q value = 1

Table S793. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
CSGALNACT2 MUTATED	0	2	0	1	0	0
CSGALNACT2 WILD-TYPE	9	15	7	11	6	5

'UQCRFS1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 1

Table S794. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
UQCRFS1 MUTATED	1	1	1	0	1
UQCRFS1 WILD-TYPE	20	18	7	8	5

'UQCRFS1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.502 (Fisher's exact test), Q value = 1

Table S795. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
UQCRFS1 MUTATED	2	1	2	0	0
UQCRFS1 WILD-TYPE	11	7	12	14	7

'UQCRFS1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S796. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
UQCRFS1 MUTATED	1	1	1	1
UQCRFS1 WILD-TYPE	16	7	13	15

'UQCRFS1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S797. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
UQCRFS1 MUTATED	1	2	0	1
UQCRFS1 WILD-TYPE	15	14	5	17

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.49 (Fisher's exact test), Q value = 1

Table S798. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
UQCRFS1 MUTATED	4	0	1
UQCRFS1 WILD-TYPE	22	12	17

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.187 (Fisher's exact test), Q value = 1

Table S799. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
UQCRFS1 MUTATED	3	0	1	1	0
UQCRFS1 WILD-TYPE	10	19	7	13	2

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.494 (Fisher's exact test), Q value = 1

Table S800. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
UQCRFS1 MUTATED	4	0	1
UQCRFS1 WILD-TYPE	23	13	15

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0508 (Fisher's exact test), Q value = 1

Table S801. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
UQCRFS1 MUTATED	3	0	0	1	0	1
UQCRFS1 WILD-TYPE	6	17	7	11	6	4

'PDCD6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S802. Gene #109: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
PDCD6 MUTATED	0	1	1	1	0
PDCD6 WILD-TYPE	21	18	7	7	6

'PDCD6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.699 (Fisher's exact test), Q value = 1

Table S803. Gene #109: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
PDCD6 MUTATED	1	0	0	1	1
PDCD6 WILD-TYPE	12	8	14	13	6

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S804. Gene #109: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
PDCD6 MUTATED	2	0	1
PDCD6 WILD-TYPE	24	12	17

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.632 (Fisher's exact test), Q value = 1

Table S805. Gene #109: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
PDCD6 MUTATED	1	1	1	0	0
PDCD6 WILD-TYPE	12	18	7	14	2

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S806. Gene #109: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
PDCD6 MUTATED	2	0	1
PDCD6 WILD-TYPE	25	13	15

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S807. Gene #109: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
PDCD6 MUTATED	1	1	1	0	0	0
PDCD6 WILD-TYPE	8	16	6	12	6	5

'PTX4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.568 (Fisher's exact test), Q value = 1

Table S808. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
PTX4 MUTATED	2	0	0	1	0
PTX4 WILD-TYPE	19	19	8	7	6

'PTX4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S809. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
PTX4 MUTATED	1	0	1	1	0
PTX4 WILD-TYPE	12	8	13	13	7

'PTX4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S810. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
PTX4 MUTATED	2	0	1	0
PTX4 WILD-TYPE	15	8	13	16

'PTX4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.217 (Fisher's exact test), Q value = 1

Table S811. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
PTX4 MUTATED	1	1	1	0
PTX4 WILD-TYPE	15	15	4	18

'PTX4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S812. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
PTX4 MUTATED	2	1	0
PTX4 WILD-TYPE	24	11	18

'PTX4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S813. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
PTX4 MUTATED	1	1	0	1	0
PTX4 WILD-TYPE	12	18	8	13	2

'PTX4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.595 (Fisher's exact test), Q value = 1

Table S814. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
PTX4 MUTATED	2	1	0
PTX4 WILD-TYPE	25	12	16

'PTX4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.392 (Fisher's exact test), Q value = 1

Table S815. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
PTX4 MUTATED	1	0	0	1	1	0
PTX4 WILD-TYPE	8	17	7	11	5	5

'SGK223 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S816. Gene #111: 'SGK223 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
SGK223 MUTATED	1	2	0	0	0
SGK223 WILD-TYPE	20	17	8	8	6

'POLRMT MUTATION STATUS' versus 'CN_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 1

Table S817. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
POLRMT MUTATED	1	1	0	1	1
POLRMT WILD-TYPE	20	18	8	7	5

'POLRMT MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0363 (Fisher's exact test), Q value = 1

Table S818. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
POLRMT MUTATED	0	0	0	2	2
POLRMT WILD-TYPE	13	8	14	12	5

Figure S61. Get High-res Image Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'POLRMT MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.327 (Fisher's exact test), Q value = 1

Table S819. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
POLRMT MUTATED	0	0	2	2
POLRMT WILD-TYPE	17	8	12	14

'POLRMT MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0737 (Fisher's exact test), Q value = 1

Table S820. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
POLRMT MUTATED	0	0	0	4
POLRMT WILD-TYPE	16	16	5	14

'POLRMT MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.189 (Fisher's exact test), Q value = 1

Table S821. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
POLRMT MUTATED	1	0	3
POLRMT WILD-TYPE	25	12	15

'POLRMT MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S822. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
POLRMT MUTATED	0	3	1	0	0
POLRMT WILD-TYPE	13	16	7	14	2

'POLRMT MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S823. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
POLRMT MUTATED	1	0	3
POLRMT WILD-TYPE	26	13	13

'POLRMT MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S824. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
POLRMT MUTATED	0	3	1	0	0	0
POLRMT WILD-TYPE	9	14	6	12	6	5

'CACNA1D MUTATION STATUS' versus 'CN_CNMF'

P value = 0.566 (Fisher's exact test), Q value = 1

Table S825. Gene #113: 'CACNA1D MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
CACNA1D MUTATED	2	0	0	1	0
CACNA1D WILD-TYPE	19	19	8	7	6

'NF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.152 (Fisher's exact test), Q value = 1

Table S826. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
NF1 MUTATED	3	1	0	3	0
NF1 WILD-TYPE	18	18	8	5	6

'NF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S827. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
NF1 MUTATED	2	0	2	2	1
NF1 WILD-TYPE	11	8	12	12	6

'NF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.41 (Fisher's exact test), Q value = 1

Table S828. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
NF1 MUTATED	4	0	2	1
NF1 WILD-TYPE	13	8	12	15

'NF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.268 (Fisher's exact test), Q value = 1

Table S829. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
NF1 MUTATED	2	2	2	1
NF1 WILD-TYPE	14	14	3	17

'NF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S830. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
NF1 MUTATED	2	3	2
NF1 WILD-TYPE	24	9	16

'NF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S831. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
NF1 MUTATED	1	2	1	3	0
NF1 WILD-TYPE	12	17	7	11	2

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0999 (Fisher's exact test), Q value = 1

Table S832. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
NF1 MUTATED	2	4	1
NF1 WILD-TYPE	25	9	15

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.527 (Fisher's exact test), Q value = 1

Table S833. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
NF1 MUTATED	1	1	0	3	1	1
NF1 WILD-TYPE	8	16	7	9	5	4

'RGMB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S834. Gene #115: 'RGMB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
RGMB MUTATED	2	2	2	0	0
RGMB WILD-TYPE	19	17	6	8	6

'ADAMTS7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.14 (Fisher's exact test), Q value = 1

Table S835. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
ADAMTS7 MUTATED	0	3	0	0	1
ADAMTS7 WILD-TYPE	21	16	8	8	5

'ADAMTS7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.575 (Fisher's exact test), Q value = 1

Table S836. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
ADAMTS7 MUTATED	0	0	1	2	1
ADAMTS7 WILD-TYPE	13	8	13	12	6

'ADAMTS7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0732 (Fisher's exact test), Q value = 1

Table S837. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
ADAMTS7 MUTATED	0	1	0	3
ADAMTS7 WILD-TYPE	17	7	14	13

'ADAMTS7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S838. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
ADAMTS7 MUTATED	0	1	0	3
ADAMTS7 WILD-TYPE	16	15	5	15

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.061 (Fisher's exact test), Q value = 1

Table S839. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
ADAMTS7 MUTATED	0	1	3
ADAMTS7 WILD-TYPE	26	11	15

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S840. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
ADAMTS7 MUTATED	0	3	1	0	0
ADAMTS7 WILD-TYPE	13	16	7	14	2

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.038 (Fisher's exact test), Q value = 1

Table S841. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
ADAMTS7 MUTATED	0	1	3
ADAMTS7 WILD-TYPE	27	12	13

Figure S62. Get High-res Image Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 1

Table S842. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
ADAMTS7 MUTATED	0	3	0	0	0	1
ADAMTS7 WILD-TYPE	9	14	7	12	6	4

'CLIC6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S843. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
CLIC6 MUTATED	3	2	0	1	0
CLIC6 WILD-TYPE	18	17	8	7	6

'CLIC6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S844. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
CLIC6 MUTATED	1	1	1	1	0
CLIC6 WILD-TYPE	12	7	13	13	7

'CLIC6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S845. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
CLIC6 MUTATED	2	1	0	1
CLIC6 WILD-TYPE	15	7	14	15

'CLIC6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.193 (Fisher's exact test), Q value = 1

Table S846. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
CLIC6 MUTATED	2	1	1	0
CLIC6 WILD-TYPE	14	15	4	18

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.246 (Fisher's exact test), Q value = 1

Table S847. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
CLIC6 MUTATED	2	2	0
CLIC6 WILD-TYPE	24	10	18

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.579 (Fisher's exact test), Q value = 1

Table S848. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
CLIC6 MUTATED	0	1	1	2	0
CLIC6 WILD-TYPE	13	18	7	12	2

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.248 (Fisher's exact test), Q value = 1

Table S849. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
CLIC6 MUTATED	2	2	0
CLIC6 WILD-TYPE	25	11	16

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S850. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
CLIC6 MUTATED	0	1	1	1	1	0
CLIC6 WILD-TYPE	9	16	6	11	5	5

'EMR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.375 (Fisher's exact test), Q value = 1

Table S851. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
EMR2 MUTATED	0	2	1	1	0
EMR2 WILD-TYPE	21	17	7	7	6

'EMR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S852. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
EMR2 MUTATED	0	0	3	1	0
EMR2 WILD-TYPE	13	8	11	13	7

'EMR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 1

Table S853. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
EMR2 MUTATED	0	1	1	2
EMR2 WILD-TYPE	17	7	13	14

'EMR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S854. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
EMR2 MUTATED	0	2	0	2
EMR2 WILD-TYPE	16	14	5	16

'EMR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.674 (Fisher's exact test), Q value = 1

Table S855. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
EMR2 MUTATED	1	1	2
EMR2 WILD-TYPE	25	11	16

'EMR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.207 (Fisher's exact test), Q value = 1

Table S856. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
EMR2 MUTATED	0	2	0	1	1
EMR2 WILD-TYPE	13	17	8	13	1

'EMR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S857. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
EMR2 MUTATED	1	1	2
EMR2 WILD-TYPE	26	12	14

'EMR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S858. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
EMR2 MUTATED	0	2	0	1	1	0
EMR2 WILD-TYPE	9	15	7	11	5	5

'PCDHB13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.513 (Fisher's exact test), Q value = 1

Table S859. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
PCDHB13 MUTATED	1	1	1	1	1
PCDHB13 WILD-TYPE	20	18	7	7	5

'PCDHB13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.139 (Fisher's exact test), Q value = 1

Table S860. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
PCDHB13 MUTATED	0	1	3	0	0
PCDHB13 WILD-TYPE	13	7	11	14	7

'PCDHB13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 1

Table S861. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
PCDHB13 MUTATED	0	0	3	1
PCDHB13 WILD-TYPE	17	8	11	15

'PCDHB13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.256 (Fisher's exact test), Q value = 1

Table S862. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
PCDHB13 MUTATED	0	3	0	1
PCDHB13 WILD-TYPE	16	13	5	17

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S863. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
PCDHB13 MUTATED	3	0	1
PCDHB13 WILD-TYPE	23	12	17

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0566 (Fisher's exact test), Q value = 1

Table S864. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
PCDHB13 MUTATED	3	0	1	0	0
PCDHB13 WILD-TYPE	10	19	7	14	2

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S865. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
PCDHB13 MUTATED	3	0	1
PCDHB13 WILD-TYPE	24	13	15

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0126 (Fisher's exact test), Q value = 1

Table S866. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
PCDHB13 MUTATED	3	0	0	0	0	1
PCDHB13 WILD-TYPE	6	17	7	12	6	4

Figure S63. Get High-res Image Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MTFMT MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S867. Gene #120: 'MTFMT MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
MTFMT MUTATED	2	1	0	0	0
MTFMT WILD-TYPE	19	18	8	8	6

'SPTAN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.244 (Fisher's exact test), Q value = 1

Table S868. Gene #121: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
SPTAN1 MUTATED	1	0	0	1	1
SPTAN1 WILD-TYPE	20	19	8	7	5

'HLA-A MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S869. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
HLA-A MUTATED	2	1	0	0	0
HLA-A WILD-TYPE	19	18	8	8	6

'HLA-A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S870. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
HLA-A MUTATED	1	0	1	1	0
HLA-A WILD-TYPE	12	8	13	13	7

'HLA-A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S871. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
HLA-A MUTATED	1	1	0	1
HLA-A WILD-TYPE	16	7	14	15

'HLA-A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.219 (Fisher's exact test), Q value = 1

Table S872. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
HLA-A MUTATED	1	1	1	0
HLA-A WILD-TYPE	15	15	4	18

'HLA-A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S873. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
HLA-A MUTATED	2	0	1
HLA-A WILD-TYPE	24	12	17

'HLA-A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S874. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
HLA-A MUTATED	1	0	1	1	0
HLA-A WILD-TYPE	12	19	7	13	2

'HLA-A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S875. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
HLA-A MUTATED	2	0	1
HLA-A WILD-TYPE	25	13	15

'HLA-A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.215 (Fisher's exact test), Q value = 1

Table S876. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
HLA-A MUTATED	0	0	1	1	0	1
HLA-A WILD-TYPE	9	17	6	11	6	4

'ASB16 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S877. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
ASB16 MUTATED	1	2	1	1	1
ASB16 WILD-TYPE	20	17	7	7	5

'ASB16 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.945 (Fisher's exact test), Q value = 1

Table S878. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
ASB16 MUTATED	1	0	1	1	1
ASB16 WILD-TYPE	12	8	13	13	6

'ASB16 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S879. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
ASB16 MUTATED	1	1	0	2
ASB16 WILD-TYPE	16	7	14	14

'ASB16 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S880. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
ASB16 MUTATED	1	2	0	1
ASB16 WILD-TYPE	15	14	5	17

'ASB16 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.543 (Fisher's exact test), Q value = 1

Table S881. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
ASB16 MUTATED	3	0	1
ASB16 WILD-TYPE	23	12	17

'ASB16 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S882. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
ASB16 MUTATED	2	1	0	1	0
ASB16 WILD-TYPE	11	18	8	13	2

'ASB16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S883. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
ASB16 MUTATED	3	0	1
ASB16 WILD-TYPE	24	13	15

'ASB16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.959 (Fisher's exact test), Q value = 1

Table S884. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
ASB16 MUTATED	1	1	1	1	0	0
ASB16 WILD-TYPE	8	16	6	11	6	5

'GPRIN2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S885. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
GPRIN2 MUTATED	2	3	2	2	0
GPRIN2 WILD-TYPE	19	16	6	6	6

'GPRIN2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.37 (Fisher's exact test), Q value = 1

Table S886. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
GPRIN2 MUTATED	1	0	4	1	1
GPRIN2 WILD-TYPE	12	8	10	13	6

'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S887. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
GPRIN2 MUTATED	1	1	3	2
GPRIN2 WILD-TYPE	16	7	11	14

'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S888. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
GPRIN2 MUTATED	1	4	0	2
GPRIN2 WILD-TYPE	15	12	5	16

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.582 (Fisher's exact test), Q value = 1

Table S889. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
GPRIN2 MUTATED	2	2	3
GPRIN2 WILD-TYPE	24	10	15

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S890. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
GPRIN2 MUTATED	1	4	1	1	0
GPRIN2 WILD-TYPE	12	15	7	13	2

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S891. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
GPRIN2 MUTATED	2	3	2
GPRIN2 WILD-TYPE	25	10	14

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.647 (Fisher's exact test), Q value = 1

Table S892. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
GPRIN2 MUTATED	1	4	0	1	0	1
GPRIN2 WILD-TYPE	8	13	7	11	6	4

'HNRNPCL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.336 (Fisher's exact test), Q value = 1

Table S893. Gene #125: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
HNRNPCL1 MUTATED	2	0	0	0	1
HNRNPCL1 WILD-TYPE	19	19	8	8	5

'BTNL9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.416 (Fisher's exact test), Q value = 1

Table S894. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
BTNL9 MUTATED	1	1	0	2	0
BTNL9 WILD-TYPE	20	18	8	6	6

'BTNL9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0962 (Fisher's exact test), Q value = 1

Table S895. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
BTNL9 MUTATED	0	0	3	0	0
BTNL9 WILD-TYPE	13	8	11	14	7

'BTNL9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S896. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
BTNL9 MUTATED	0	1	2	0
BTNL9 WILD-TYPE	17	7	12	16

'BTNL9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0618 (Fisher's exact test), Q value = 1

Table S897. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
BTNL9 MUTATED	0	3	0	0
BTNL9 WILD-TYPE	16	13	5	18

'BTNL9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.142 (Fisher's exact test), Q value = 1

Table S898. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
BTNL9 MUTATED	1	2	0
BTNL9 WILD-TYPE	25	10	18

'BTNL9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S899. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
BTNL9 MUTATED	1	1	0	1	0
BTNL9 WILD-TYPE	12	18	8	13	2

'BTNL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 1

Table S900. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
BTNL9 MUTATED	1	2	0
BTNL9 WILD-TYPE	26	11	16

'BTNL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S901. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
BTNL9 MUTATED	1	1	0	1	0	0
BTNL9 WILD-TYPE	8	16	7	11	6	5

'KCNJ11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0135 (Fisher's exact test), Q value = 1

Table S902. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
KCNJ11 MUTATED	0	1	3	0	0
KCNJ11 WILD-TYPE	21	18	5	8	6

Figure S64. Get High-res Image Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'KCNJ11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S903. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
KCNJ11 MUTATED	1	1	2	0	0
KCNJ11 WILD-TYPE	12	7	12	14	7

'KCNJ11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S904. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
KCNJ11 MUTATED	1	1	2	0
KCNJ11 WILD-TYPE	16	7	12	16

'KCNJ11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.14 (Fisher's exact test), Q value = 1

Table S905. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
KCNJ11 MUTATED	1	3	0	0
KCNJ11 WILD-TYPE	15	13	5	18

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 1

Table S906. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
KCNJ11 MUTATED	4	0	0
KCNJ11 WILD-TYPE	22	12	18

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0498 (Fisher's exact test), Q value = 1

Table S907. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
KCNJ11 MUTATED	2	0	0	1	1
KCNJ11 WILD-TYPE	11	19	8	13	1

Figure S65. Get High-res Image Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S908. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
KCNJ11 MUTATED	4	0	0
KCNJ11 WILD-TYPE	23	13	16

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.211 (Fisher's exact test), Q value = 1

Table S909. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
KCNJ11 MUTATED	2	0	0	1	1	0
KCNJ11 WILD-TYPE	7	17	7	11	5	5

'JMJD4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S910. Gene #128: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
JMJD4 MUTATED	1	1	1	0	0
JMJD4 WILD-TYPE	20	18	7	8	6

'LRRC4B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.188 (Fisher's exact test), Q value = 1

Table S911. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
LRRC4B MUTATED	3	0	2	1	0
LRRC4B WILD-TYPE	18	19	6	7	6

'LRRC4B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.189 (Fisher's exact test), Q value = 1

Table S912. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
LRRC4B MUTATED	4	0	1	1	0
LRRC4B WILD-TYPE	9	8	13	13	7

'LRRC4B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0133 (Fisher's exact test), Q value = 1

Table S913. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
LRRC4B MUTATED	5	1	0	0
LRRC4B WILD-TYPE	12	7	14	16

Figure S66. Get High-res Image Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'LRRC4B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0708 (Fisher's exact test), Q value = 1

Table S914. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
LRRC4B MUTATED	4	1	1	0
LRRC4B WILD-TYPE	12	15	4	18

'LRRC4B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S915. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
LRRC4B MUTATED	4	2	0
LRRC4B WILD-TYPE	22	10	18

'LRRC4B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0299 (Fisher's exact test), Q value = 1

Table S916. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
LRRC4B MUTATED	0	1	0	4	1
LRRC4B WILD-TYPE	13	18	8	10	1

Figure S67. Get High-res Image Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'LRRC4B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S917. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
LRRC4B MUTATED	5	1	0
LRRC4B WILD-TYPE	22	12	16

'LRRC4B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00974 (Fisher's exact test), Q value = 1

Table S918. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
LRRC4B MUTATED	0	0	0	4	2	0
LRRC4B WILD-TYPE	9	17	7	8	4	5

Figure S68. Get High-res Image Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'OPLAH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.566 (Fisher's exact test), Q value = 1

Table S919. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
OPLAH MUTATED	2	0	1	0	0
OPLAH WILD-TYPE	19	19	7	8	6

'OPLAH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S920. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
OPLAH MUTATED	1	1	1	0	0
OPLAH WILD-TYPE	12	7	13	14	7

'OPLAH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S921. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
OPLAH MUTATED	2	0	1	0
OPLAH WILD-TYPE	15	8	13	16

'OPLAH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S922. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
OPLAH MUTATED	2	1	0	0
OPLAH WILD-TYPE	14	15	5	18

'OPLAH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S923. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
OPLAH MUTATED	2	1	0
OPLAH WILD-TYPE	24	11	18

'OPLAH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S924. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
OPLAH MUTATED	1	0	0	2	0
OPLAH WILD-TYPE	12	19	8	12	2

'OPLAH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S925. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
OPLAH MUTATED	2	1	0
OPLAH WILD-TYPE	25	12	16

'OPLAH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S926. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
OPLAH MUTATED	1	0	0	1	1	0
OPLAH WILD-TYPE	8	17	7	11	5	5

'BAGE2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S927. Gene #131: 'BAGE2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
BAGE2 MUTATED	1	2	0	0	0
BAGE2 WILD-TYPE	20	17	8	8	6

'MADCAM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S928. Gene #132: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
MADCAM1 MUTATED	0	2	1	0	0
MADCAM1 WILD-TYPE	21	17	7	8	6

'MADCAM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S929. Gene #132: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
MADCAM1 MUTATED	1	0	0	1	1
MADCAM1 WILD-TYPE	12	8	14	13	6

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S930. Gene #132: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
MADCAM1 MUTATED	2	0	1
MADCAM1 WILD-TYPE	24	12	17

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S931. Gene #132: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
MADCAM1 MUTATED	2	0	1	0	0
MADCAM1 WILD-TYPE	11	19	7	14	2

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S932. Gene #132: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
MADCAM1 MUTATED	2	0	1
MADCAM1 WILD-TYPE	25	13	15

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.136 (Fisher's exact test), Q value = 1

Table S933. Gene #132: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
MADCAM1 MUTATED	1	0	1	0	0	1
MADCAM1 WILD-TYPE	8	17	6	12	6	4

'CTBP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S934. Gene #133: 'CTBP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
CTBP2 MUTATED	1	2	0	0	0
CTBP2 WILD-TYPE	20	17	8	8	6

'MSH3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0176 (Fisher's exact test), Q value = 1

Table S935. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
MSH3 MUTATED	1	0	0	3	0
MSH3 WILD-TYPE	20	19	8	5	6

Figure S69. Get High-res Image Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'MSH3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.7 (Fisher's exact test), Q value = 1

Table S936. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
MSH3 MUTATED	1	0	1	0	1
MSH3 WILD-TYPE	12	8	13	14	6

'MSH3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.335 (Fisher's exact test), Q value = 1

Table S937. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
MSH3 MUTATED	1	0	2	0
MSH3 WILD-TYPE	16	8	12	16

'MSH3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S938. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
MSH3 MUTATED	1	1	0	1
MSH3 WILD-TYPE	15	15	5	17

'MSH3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S939. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
MSH3 MUTATED	3	0	0
MSH3 WILD-TYPE	23	12	18

'MSH3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S940. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
MSH3 MUTATED	1	0	1	1	0
MSH3 WILD-TYPE	12	19	7	13	2

'MSH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S941. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
MSH3 MUTATED	3	0	0
MSH3 WILD-TYPE	24	13	16

'MSH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.495 (Fisher's exact test), Q value = 1

Table S942. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
MSH3 MUTATED	1	0	1	1	0	0
MSH3 WILD-TYPE	8	17	6	11	6	5

'ATN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 1

Table S943. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
ATN1 MUTATED	0	2	0	2	0
ATN1 WILD-TYPE	21	17	8	6	6

'ATN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S944. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
ATN1 MUTATED	1	1	0	1	0
ATN1 WILD-TYPE	12	7	14	13	7

'ATN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S945. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
ATN1 MUTATED	1	1	0	1
ATN1 WILD-TYPE	16	7	14	15

'ATN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S946. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
ATN1 MUTATED	1	1	0	1
ATN1 WILD-TYPE	15	15	5	17

'ATN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S947. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
ATN1 MUTATED	1	1	1
ATN1 WILD-TYPE	25	11	17

'ATN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S948. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
ATN1 MUTATED	1	2	0	0	0
ATN1 WILD-TYPE	12	17	8	14	2

'ATN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S949. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
ATN1 MUTATED	1	1	1
ATN1 WILD-TYPE	26	12	15

'ATN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S950. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
ATN1 MUTATED	1	2	0	0	0	0
ATN1 WILD-TYPE	8	15	7	12	6	5

'FAM46A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.897 (Fisher's exact test), Q value = 1

Table S951. Gene #136: 'FAM46A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
FAM46A MUTATED	1	2	0	0	0
FAM46A WILD-TYPE	20	17	8	8	6

'UTS2R MUTATION STATUS' versus 'CN_CNMF'

P value = 0.162 (Fisher's exact test), Q value = 1

Table S952. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
UTS2R MUTATED	0	1	0	1	1
UTS2R WILD-TYPE	21	18	8	7	5

'UTS2R MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.699 (Fisher's exact test), Q value = 1

Table S953. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
UTS2R MUTATED	1	0	0	1	1
UTS2R WILD-TYPE	12	8	14	13	6

'UTS2R MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.69 (Fisher's exact test), Q value = 1

Table S954. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
UTS2R MUTATED	1	0	0	2
UTS2R WILD-TYPE	16	8	14	14

'UTS2R MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S955. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
UTS2R MUTATED	1	0	0	2
UTS2R WILD-TYPE	15	16	5	16

'UTS2R MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S956. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
UTS2R MUTATED	1	0	2
UTS2R WILD-TYPE	25	12	16

'UTS2R MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S957. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
UTS2R MUTATED	1	2	0	0	0
UTS2R WILD-TYPE	12	17	8	14	2

'UTS2R MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S958. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
UTS2R MUTATED	1	0	2
UTS2R WILD-TYPE	26	13	14

'UTS2R MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S959. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
UTS2R MUTATED	1	2	0	0	0	0
UTS2R WILD-TYPE	8	15	7	12	6	5

'SMG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.164 (Fisher's exact test), Q value = 1

Table S960. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
SMG1 MUTATED	0	1	1	0	1
SMG1 WILD-TYPE	21	18	7	8	5

'SMG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S961. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
SMG1 MUTATED	0	2	1	0	0
SMG1 WILD-TYPE	13	6	13	14	7

'SMG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.143 (Fisher's exact test), Q value = 1

Table S962. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
SMG1 MUTATED	0	1	2	0
SMG1 WILD-TYPE	17	7	12	16

'SMG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0621 (Fisher's exact test), Q value = 1

Table S963. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
SMG1 MUTATED	0	3	0	0
SMG1 WILD-TYPE	16	13	5	18

'SMG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 1

Table S964. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
SMG1 MUTATED	3	0	0
SMG1 WILD-TYPE	23	12	18

'SMG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0256 (Fisher's exact test), Q value = 1

Table S965. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
SMG1 MUTATED	1	0	1	0	1
SMG1 WILD-TYPE	12	19	7	14	1

Figure S70. Get High-res Image Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'SMG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S966. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
SMG1 MUTATED	3	0	0
SMG1 WILD-TYPE	24	13	16

'SMG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.188 (Fisher's exact test), Q value = 1

Table S967. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
SMG1 MUTATED	1	0	1	0	1	0
SMG1 WILD-TYPE	8	17	6	12	5	5

'FUCA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.404 (Fisher's exact test), Q value = 1

Table S968. Gene #139: 'FUCA1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
FUCA1 MUTATED	1	0	1	1	0
FUCA1 WILD-TYPE	20	19	7	7	6

'FEZ2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S969. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
FEZ2 MUTATED	0	2	1	0	0
FEZ2 WILD-TYPE	21	17	7	8	6

'FEZ2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S970. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
FEZ2 MUTATED	0	1	1	0	1
FEZ2 WILD-TYPE	13	7	13	14	6

'FEZ2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.179 (Fisher's exact test), Q value = 1

Table S971. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
FEZ2 MUTATED	0	1	0	2
FEZ2 WILD-TYPE	17	7	14	14

'FEZ2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S972. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
FEZ2 MUTATED	1	0	0	2
FEZ2 WILD-TYPE	15	16	5	16

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 1

Table S973. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
FEZ2 MUTATED	0	1	2
FEZ2 WILD-TYPE	26	11	16

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.709 (Fisher's exact test), Q value = 1

Table S974. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
FEZ2 MUTATED	0	1	1	1	0
FEZ2 WILD-TYPE	13	18	7	13	2

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 1

Table S975. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
FEZ2 MUTATED	0	1	2
FEZ2 WILD-TYPE	27	12	14

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S976. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
FEZ2 MUTATED	0	1	0	1	0	1
FEZ2 WILD-TYPE	9	16	7	11	6	4

'GLI3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.737 (Fisher's exact test), Q value = 1

Table S977. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
GLI3 MUTATED	3	1	0	1	0
GLI3 WILD-TYPE	18	18	8	7	6

'GLI3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S978. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
GLI3 MUTATED	2	0	0	1	1
GLI3 WILD-TYPE	11	8	14	13	6

'GLI3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S979. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
GLI3 MUTATED	2	0	1	1
GLI3 WILD-TYPE	15	8	13	15

'GLI3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S980. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
GLI3 MUTATED	2	1	0	1
GLI3 WILD-TYPE	14	15	5	17

'GLI3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.134 (Fisher's exact test), Q value = 1

Table S981. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
GLI3 MUTATED	4	0	0
GLI3 WILD-TYPE	22	12	18

'GLI3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S982. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
GLI3 MUTATED	1	0	1	2	0
GLI3 WILD-TYPE	12	19	7	12	2

'GLI3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 1

Table S983. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
GLI3 MUTATED	4	0	0
GLI3 WILD-TYPE	23	13	16

'GLI3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0919 (Fisher's exact test), Q value = 1

Table S984. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
GLI3 MUTATED	0	0	2	2	0	0
GLI3 WILD-TYPE	9	17	5	10	6	5

'NOL9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00202 (Fisher's exact test), Q value = 1

Table S985. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	21	19	8	8	6
NOL9 MUTATED	0	0	0	3	1
NOL9 WILD-TYPE	21	19	8	5	5

Figure S71. Get High-res Image Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'NOL9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S986. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	14	7
NOL9 MUTATED	1	0	1	1	0
NOL9 WILD-TYPE	12	8	13	13	7

'NOL9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S987. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	17	8	14	16
NOL9 MUTATED	1	0	1	1
NOL9 WILD-TYPE	16	8	13	15

'NOL9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S988. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	5	18
NOL9 MUTATED	1	1	0	1
NOL9 WILD-TYPE	15	15	5	17

'NOL9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.789 (Fisher's exact test), Q value = 1

Table S989. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	12	18
NOL9 MUTATED	1	1	1
NOL9 WILD-TYPE	25	11	17

'NOL9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.559 (Fisher's exact test), Q value = 1

Table S990. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	19	8	14	2
NOL9 MUTATED	0	1	0	2	0
NOL9 WILD-TYPE	13	18	8	12	2

'NOL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S991. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	27	13	16
NOL9 MUTATED	1	1	1
NOL9 WILD-TYPE	26	12	15

'NOL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S992. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6
ALL	9	17	7	12	6	5
NOL9 MUTATED	0	1	0	2	0	0
NOL9 WILD-TYPE	9	16	7	10	6	5

Methods & Data

Input

Mutation data file = transformed.cor.cli.txt
Molecular subtypes file = ACC-TP.transferedmergedcluster.txt
Number of patients = 64
Number of significantly mutated genes = 142
Number of Molecular subtypes = 8
Exclude genes that fewer than K tumors have mutations, K = 3

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

Download Results

In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.

References

[1] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)

[2] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)

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