Correlation between gene mutation status and molecular subtypes
Adrenocortical Carcinoma (Primary solid tumor)
15 July 2014 | analyses__2014_07_15
Maintainer Information
Citation Information
doi:10.7908/C1QC026W
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2014): Correlation between gene mutation status and molecular subtypes. Broad Institute of MIT and Harvard. doi:10.7908/C1QC026W
Overview
Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 142 genes and 8 molecular subtypes across 64 patients, no significant finding detected with P value < 0.05 and Q value < 0.25.

- No gene mutations related to molecuar subtypes.

Results
Overview of the results

Table 1. Get Full Table Overview of the association between mutation status of 142 genes and 8 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, no significant finding detected.

|  | Clinical Features | CN CNMF | METHLYATION CNMF | MRNASEQ CNMF | MRNASEQ CHIERARCHICAL | MIRSEQ CNMF | MIRSEQ CHIERARCHICAL | MIRSEQ MATURE CNMF | MIRSEQ MATURE CHIERARCHICAL
| nMutated (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test
ZFPM1 | 26 (41%) | 38 | 0.181 (1.00) | 0.81 (1.00) | 0.335 (1.00) | 0.819 (1.00) | 0.68 (1.00) | 0.838 (1.00) | 0.492 (1.00) | 0.938 (1.00)
LACTB | 20 (31%) | 44 | 0.117 (1.00) | 0.682 (1.00) | 1 (1.00) | 0.56 (1.00) | 0.454 (1.00) | 0.743 (1.00) | 0.314 (1.00) | 0.756 (1.00)
CCDC102A | 17 (27%) | 47 | 0.131 (1.00) | 0.936 (1.00) | 0.911 (1.00) | 0.758 (1.00) | 0.439 (1.00) | 0.476 (1.00) | 0.687 (1.00) | 0.145 (1.00)
ZNF517 | 13 (20%) | 51 | 0.652 (1.00) | 0.962 (1.00) | 0.884 (1.00) | 1 (1.00) | 0.236 (1.00) | 0.667 (1.00) | 0.799 (1.00) | 0.427 (1.00)
TOR3A | 12 (19%) | 52 | 0.273 (1.00) | 0.0221 (1.00) | 0.638 (1.00) | 0.0151 (1.00) | 1 (1.00) | 0.868 (1.00) | 0.828 (1.00) | 0.662 (1.00)
USP42 | 16 (25%) | 48 | 0.725 (1.00) | 0.0487 (1.00) | 1 (1.00) | 0.96 (1.00) | 0.567 (1.00) | 0.839 (1.00) | 0.748 (1.00) | 0.289 (1.00)
CLDN23 | 10 (16%) | 54 | 0.263 (1.00) | 0.247 (1.00) | 0.0237 (1.00) | 0.181 (1.00) | 0.0905 (1.00) | 0.19 (1.00) | 0.108 (1.00) | 0.322 (1.00)
TP53 | 13 (20%) | 51 | 0.0216 (1.00) | 0.775 (1.00) | 0.0201 (1.00) | 0.666 (1.00) | 0.018 (1.00) | 0.638 (1.00) | 0.0416 (1.00) | 0.192 (1.00)
KCNK17 | 9 (14%) | 55 | 0.103 (1.00) | 0.0379 (1.00) | 0.0944 (1.00) | 0.00996 (1.00) | 1 (1.00) | 0.522 (1.00) | 0.474 (1.00) | 0.417 (1.00)
LZTR1 | 6 (9%) | 58 | 0.224 (1.00) | 0.806 (1.00) | 0.0894 (1.00) | 0.194 (1.00) | 0.417 (1.00) | 0.0137 (1.00) | 0.445 (1.00) | 0.0854 (1.00)
APOE | 7 (11%) | 57 | 0.17 (1.00) | 0.62 (1.00) | 0.0669 (1.00) | 0.453 (1.00) | 0.279 (1.00) | 0.822 (1.00) | 0.027 (1.00) | 0.825 (1.00)
CCDC105 | 7 (11%) | 57 | 0.169 (1.00) | 0.00859 (1.00) | 0.881 (1.00) | 0.714 (1.00) | 1 (1.00) | 0.0509 (1.00) | 0.859 (1.00) | 0.326 (1.00)
RINL | 8 (12%) | 56 | 0.146 (1.00) | 0.701 (1.00) | 0.509 (1.00) | 0.294 (1.00) | 0.882 (1.00) | 0.166 (1.00) | 0.438 (1.00) | 0.187 (1.00)
MAL2 | 12 (19%) | 52 | 0.782 (1.00) | 0.303 (1.00) | 0.199 (1.00) | 0.518 (1.00) | 0.123 (1.00) | 0.277 (1.00) | 0.644 (1.00) | 0.321 (1.00)
LRIG1 | 17 (27%) | 47 | 0.654 (1.00) | 0.894 (1.00) | 1 (1.00) | 0.781 (1.00) | 0.186 (1.00) | 0.496 (1.00) | 0.696 (1.00) | 0.874 (1.00)
C19ORF10 | 8 (12%) | 56 | 0.633 (1.00) | 0.355 (1.00) | 0.235 (1.00) | 0.109 (1.00) | 0.55 (1.00) | 0.86 (1.00) | 0.287 (1.00) | 0.761 (1.00)
C10ORF95 | 7 (11%) | 57 | 0.172 (1.00) | 0.707 (1.00) | 0.557 (1.00) | 0.817 (1.00) | 0.75 (1.00) | 0.491 (1.00) | 0.862 (1.00) | 0.505 (1.00)
SYT8 | 9 (14%) | 55 | 0.428 (1.00) | 0.403 (1.00) | 0.0346 (1.00) | 0.147 (1.00) | 1 (1.00) | 0.216 (1.00) | 1 (1.00) | 0.643 (1.00)
IDUA | 9 (14%) | 55 | 0.545 (1.00) | 0.894 (1.00) | 0.345 (1.00) | 0.54 (1.00) | 0.122 (1.00) | 0.457 (1.00) | 0.196 (1.00) | 0.483 (1.00)
HHIPL1 | 8 (12%) | 56 | 0.126 (1.00) | 0.285 (1.00) | 0.358 (1.00) | 0.204 (1.00) | 0.176 (1.00) | 0.786 (1.00) | 0.289 (1.00) | 0.201 (1.00)
ASPDH | 8 (12%) | 56 | 0.306 (1.00) | 0.644 (1.00) | 0.0203 (1.00) | 0.344 (1.00) | 0.476 (1.00) | 0.0277 (1.00) | 0.368 (1.00) | 0.0793 (1.00)
C1ORF106 | 9 (14%) | 55 | 0.77 (1.00) | 0.434 (1.00) | 0.343 (1.00) | 0.861 (1.00) | 0.478 (1.00) | 0.689 (1.00) | 0.616 (1.00) | 1 (1.00)
THEM4 | 6 (9%) | 58 | 0.00358 (1.00) | 0.734 (1.00) | 0.437 (1.00) | 0.886 (1.00) | 0.245 (1.00) | 0.0938 (1.00) | 0.25 (1.00) | 0.111 (1.00)
CTNNB1 | 7 (11%) | 57 | 1 (1.00) | 0.167 (1.00) | 0.0194 (1.00) | 0.0181 (1.00) | 0.00174 (1.00) | 0.169 (1.00) | 0.0272 (1.00) | 0.48 (1.00)
GDF1 | 5 (8%) | 59 | 0.396 (1.00) | 0.312 (1.00) | 0.362 (1.00) | 0.254 (1.00) | 0.0896 (1.00) | 0.54 (1.00) | 0.0192 (1.00) | 0.713 (1.00)
TSC22D2 | 8 (12%) | 56 | 0.349 (1.00) | 0.528 (1.00) | 0.815 (1.00) | 0.942 (1.00) | 0.883 (1.00) | 0.426 (1.00) | 1 (1.00) | 0.334 (1.00)
ZAR1 | 11 (17%) | 53 | 0.175 (1.00) | 0.667 (1.00) | 0.602 (1.00) | 0.802 (1.00) | 0.72 (1.00) | 1 (1.00) | 0.52 (1.00) | 0.715 (1.00)
RGS9BP | 8 (12%) | 56 | 0.295 (1.00) | 0.585 (1.00) | 1 (1.00) | 0.888 (1.00) | 0.335 (1.00) | 0.962 (1.00) | 0.884 (1.00) | 0.343 (1.00)
OPRD1 | 12 (19%) | 52 | 0.824 (1.00) | 0.388 (1.00) | 0.797 (1.00) | 0.961 (1.00) | 0.34 (1.00) | 0.631 (1.00) | 0.469 (1.00) | 0.466 (1.00)
C16ORF3 | 6 (9%) | 58 | 0.904 (1.00) | 0.00079 (0.784) | 0.799 (1.00) | 0.831 (1.00) | 0.594 (1.00) | 1 (1.00) | 0.698 (1.00) | 0.711 (1.00)
FPGS | 6 (9%) | 58 | 1 (1.00) | 1 (1.00) | 0.614 (1.00) | 0.614 (1.00) | 0.0905 (1.00) | 0.624 (1.00) | 0.675 (1.00) | 0.787 (1.00)
PLIN5 | 5 (8%) | 59 | 0.561 (1.00) | 0.693 (1.00) | 0.799 (1.00) | 0.542 (1.00) | 0.35 (1.00) | 0.308 (1.00) | 0.129 (1.00) | 0.321 (1.00)
IRX3 | 5 (8%) | 59 | 0.333 (1.00) | 0.733 (1.00) | 0.52 (1.00) | 0.193 (1.00) | 0.246 (1.00) | 0.779 (1.00) | 0.25 (1.00) | 0.0204 (1.00)
TRIOBP | 12 (19%) | 52 | 0.821 (1.00) | 0.176 (1.00) | 1 (1.00) | 0.128 (1.00) | 0.902 (1.00) | 0.93 (1.00) | 0.665 (1.00) | 0.746 (1.00)
KRTAP4-5 | 5 (8%) | 59 | 0.769 (1.00) | 0.313 (1.00) | 1 (1.00) | 0.886 (1.00) | 1 (1.00) | 0.84 (1.00) | 1 (1.00) | 0.894 (1.00)
ATXN1 | 10 (16%) | 54 | 0.408 (1.00) | 0.129 (1.00) | 0.234 (1.00) | 0.627 (1.00) | 0.324 (1.00) | 0.852 (1.00) | 0.41 (1.00) | 0.851 (1.00)
ZNF628 | 7 (11%) | 57 | 0.305 (1.00) | 0.892 (1.00) | 0.351 (1.00) | 0.122 (1.00) | 0.125 (1.00) | 0.494 (1.00) | 0.0953 (1.00) | 0.725 (1.00)
WDR34 | 5 (8%) | 59 | 0.674 (1.00) | 0.772 (1.00) | 0.931 (1.00) | 0.834 (1.00) | 0.843 (1.00) | 0.523 (1.00) | 1 (1.00) | 0.396 (1.00)
BTBD11 | 6 (9%) | 58 | 1 (1.00) | 0.235 (1.00) | 0.48 (1.00) | 1 (1.00) | 0.493 (1.00) | 0.165 (1.00) | 0.491 (1.00) | 0.213 (1.00)
GARS | 21 (33%) | 43 | 0.236 (1.00) | 0.0685 (1.00) | 0.433 (1.00) | 0.063 (1.00) | 0.238 (1.00) | 0.339 (1.00) | 0.0989 (1.00) | 0.342 (1.00)
ZNF598 | 13 (20%) | 51 | 0.446 (1.00) | 0.377 (1.00) | 0.534 (1.00) | 1 (1.00) | 1 (1.00) | 0.215 (1.00) | 1 (1.00) | 0.162 (1.00)
BHLHE22 | 5 (8%) | 59 | 0.391 (1.00) | 0.0641 (1.00) | 0.104 (1.00) | 0.83 (1.00) | 0.595 (1.00) | 0.881 (1.00) | 0.698 (1.00) | 0.785 (1.00)
PTPLA | 4 (6%) | 60 | 0.441 (1.00) | 0.292 (1.00) | 0.332 (1.00) | 0.474 (1.00) | 0.79 (1.00) | 1 (1.00) | 0.21 (1.00) | 0.583 (1.00)
CD320 | 4 (6%) | 60 | 0.935 (1.00) | 0.897 (1.00) | 0.737 (1.00) | 0.684 (1.00) | 0.416 (1.00) | 0.221 (1.00) | 0.175 (1.00) | 0.173 (1.00)
KIAA1984 | 4 (6%) | 60 | 0.252 (1.00) | 0.735 (1.00) | 0.126 (1.00) | 0.0463 (1.00) | 0.0364 (1.00) | 0.58 (1.00) | 0.0617 (1.00) | 0.669 (1.00)
TPO | 12 (19%) | 52 | 0.532 (1.00) | 0.305 (1.00) | 0.214 (1.00) | 0.159 (1.00) | 0.14 (1.00) | 0.319 (1.00) | 0.28 (1.00) | 0.122 (1.00)
AATK | 6 (9%) | 58 | 0.115 (1.00) | 0.316 (1.00) | 0.36 (1.00) | 0.251 (1.00) | 1 (1.00) | 0.506 (1.00) | 1 (1.00) | 0.455 (1.00)
PANK2 | 5 (8%) | 59 | 0.735 (1.00) | 0.428 (1.00) | 0.114 (1.00) | 0.108 (1.00) | 0.441 (1.00) | 0.342 (1.00) | 0.594 (1.00) | 0.323 (1.00)
SNED1 | 6 (9%) | 58 | 0.394 (1.00) | 0.594 (1.00) | 0.212 (1.00) | 0.455 (1.00) | 0.0442 (1.00) | 0.649 (1.00) | 0.0459 (1.00) | 0.321 (1.00)
CCDC150 | 4 (6%) | 60 | 0.441 (1.00) | 0.808 (1.00) | 0.265 (1.00) | 0.197 (1.00) | 0.417 (1.00) | 0.182 (1.00) | 0.442 (1.00) | 0.143 (1.00)
ERCC2 | 10 (16%) | 54 | 0.756 (1.00) | 0.196 (1.00) | 0.51 (1.00) | 0.149 (1.00) | 0.671 (1.00) | 0.239 (1.00) | 0.29 (1.00) | 0.0884 (1.00)
RREB1 | 5 (8%) | 59 | 0.736 (1.00) | 0.807 (1.00) | 0.612 (1.00) | 1 (1.00) | 0.675 (1.00) | 0.504 (1.00) | 0.675 (1.00) | 0.554 (1.00)
RNF39 | 5 (8%) | 59 | 0.427 (1.00) | 0.311 (1.00) | 0.184 (1.00) | 0.267 (1.00) | 0.167 (1.00) | 0.695 (1.00) | 0.351 (1.00) | 0.553 (1.00)
SEMA5B | 8 (12%) | 56 | 0.39 (1.00) | 0.35 (1.00) | 0.399 (1.00) | 0.274 (1.00) | 0.853 (1.00) | 0.337 (1.00) | 0.637 (1.00) | 0.666 (1.00)
TAF5 | 4 (6%) | 60 | 0.937 (1.00) | 0.733 (1.00) | 1 (1.00) | 0.884 (1.00) | 0.0212 (1.00) | 0.121 (1.00) | 0.0195 (1.00) | 0.197 (1.00)
SARM1 | 7 (11%) | 57 | 0.0301 (1.00) | 0.435 (1.00) | 0.275 (1.00) | 0.0285 (1.00) | 0.113 (1.00) | 0.754 (1.00) | 0.046 (1.00) | 0.917 (1.00)
PRSS27 | 3 (5%) | 61 | 0.797 (1.00) | 0.909 (1.00) | 0.609 (1.00) | 0.108 (1.00) | 0.141 (1.00) | 1 (1.00) | 0.206 (1.00) | 1 (1.00)
TMEM189 | 4 (6%) | 60 | 0.162 (1.00) |  |  |  |  |  |  |
NOXA1 | 5 (8%) | 59 | 0.15 (1.00) | 0.426 (1.00) | 0.219 (1.00) | 0.476 (1.00) | 0.302 (1.00) | 0.341 (1.00) | 0.314 (1.00) | 0.328 (1.00)
LRP11 | 7 (11%) | 57 | 0.0406 (1.00) | 0.0727 (1.00) | 0.799 (1.00) | 0.541 (1.00) | 0.593 (1.00) | 0.936 (1.00) | 0.695 (1.00) | 0.95 (1.00)
RNF149 | 4 (6%) | 60 | 0.376 (1.00) | 0.0356 (1.00) | 0.36 (1.00) | 0.616 (1.00) | 0.329 (1.00) | 0.353 (1.00) | 0.343 (1.00) | 0.444 (1.00)
DMKN | 3 (5%) | 61 | 0.801 (1.00) | 0.292 (1.00) | 0.611 (1.00) | 0.474 (1.00) | 0.00831 (1.00) | 0.56 (1.00) | 0.0101 (1.00) | 0.823 (1.00)
FANK1 | 4 (6%) | 60 | 0.936 (1.00) | 0.35 (1.00) | 0.855 (1.00) | 0.328 (1.00) | 0.79 (1.00) | 0.227 (1.00) | 1 (1.00) | 0.172 (1.00)
MUC5B | 22 (34%) | 42 | 1 (1.00) | 0.572 (1.00) | 0.676 (1.00) | 0.731 (1.00) | 0.817 (1.00) | 0.631 (1.00) | 0.591 (1.00) | 0.846 (1.00)
PABPC1 | 4 (6%) | 60 | 0.415 (1.00) |  |  |  |  |  |  |
GLTPD2 | 6 (9%) | 58 | 0.0714 (1.00) | 0.844 (1.00) | 0.883 (1.00) | 0.453 (1.00) | 0.553 (1.00) | 0.51 (1.00) | 0.858 (1.00) | 0.597 (1.00)
MEN1 | 5 (8%) | 59 | 0.0955 (1.00) | 0.0433 (1.00) | 0.0127 (1.00) | 0.00613 (1.00) | 0.215 (1.00) | 0.0387 (1.00) | 0.351 (1.00) | 0.00889 (1.00)
SRPX | 3 (5%) | 61 | 0.894 (1.00) | 0.125 (1.00) | 0.468 (1.00) | 1 (1.00) | 0.789 (1.00) | 0.789 (1.00) | 1 (1.00) | 0.822 (1.00)
MAP1S | 5 (8%) | 59 | 0.276 (1.00) | 0.384 (1.00) | 0.349 (1.00) | 1 (1.00) | 1 (1.00) | 0.882 (1.00) | 0.842 (1.00) | 1 (1.00)
SCRT1 | 3 (5%) | 61 | 0.799 (1.00) | 0.425 (1.00) | 0.609 (1.00) | 0.639 (1.00) | 0.441 (1.00) | 0.71 (1.00) | 0.592 (1.00) | 0.875 (1.00)
OBSCN | 20 (31%) | 44 | 0.657 (1.00) | 0.261 (1.00) | 0.458 (1.00) | 0.624 (1.00) | 0.0945 (1.00) | 0.78 (1.00) | 0.196 (1.00) | 0.73 (1.00)
IER5 | 3 (5%) | 61 | 0.369 (1.00) |  |  |  |  |  |  |
TNIP2 | 5 (8%) | 59 | 0.673 (1.00) | 0.625 (1.00) | 0.735 (1.00) | 0.887 (1.00) | 1 (1.00) | 0.402 (1.00) | 1 (1.00) | 0.235 (1.00)
NOTCH2 | 7 (11%) | 57 | 0.304 (1.00) | 0.798 (1.00) | 0.35 (1.00) | 0.0338 (1.00) | 0.00835 (1.00) | 0.417 (1.00) | 0.00893 (1.00) | 0.325 (1.00)
RASIP1 | 7 (11%) | 57 | 0.63 (1.00) | 0.676 (1.00) | 0.0391 (1.00) | 0.159 (1.00) | 0.022 (1.00) | 0.686 (1.00) | 0.0377 (1.00) | 0.748 (1.00)
NMU | 5 (8%) | 59 | 0.821 (1.00) | 1 (1.00) | 0.0485 (1.00) | 0.639 (1.00) | 1 (1.00) | 0.506 (1.00) | 1 (1.00) | 0.455 (1.00)
VARS | 6 (9%) | 58 | 0.445 (1.00) | 0.437 (1.00) | 0.185 (1.00) | 0.0818 (1.00) | 0.854 (1.00) | 0.861 (1.00) | 0.34 (1.00) | 0.762 (1.00)
SHOX2 | 3 (5%) | 61 | 0.334 (1.00) |  |  |  |  |  |  |
HSD17B1 | 4 (6%) | 60 | 1 (1.00) | 0.108 (1.00) | 1 (1.00) | 0.0127 (1.00) | 1 (1.00) | 0.84 (1.00) | 1 (1.00) | 0.762 (1.00)
COQ2 | 5 (8%) | 59 | 0.296 (1.00) | 0.765 (1.00) | 0.361 (1.00) | 0.616 (1.00) | 1 (1.00) | 0.669 (1.00) | 1 (1.00) | 0.762 (1.00)
KNDC1 | 10 (16%) | 54 | 0.785 (1.00) | 0.129 (1.00) | 0.141 (1.00) | 0.372 (1.00) | 0.288 (1.00) | 0.357 (1.00) | 0.228 (1.00) | 0.749 (1.00)
AR | 4 (6%) | 60 | 0.32 (1.00) | 0.426 (1.00) | 0.61 (1.00) | 0.472 (1.00) | 0.445 (1.00) | 1 (1.00) | 0.596 (1.00) | 1 (1.00)
KCTD3 | 4 (6%) | 60 | 0.414 (1.00) |  |  |  |  |  |  |
FZD1 | 3 (5%) | 61 | 0.407 (1.00) |  |  |  |  |  |  |
ZC3H12D | 3 (5%) | 61 | 0.0033 (1.00) |  |  |  |  |  |  |
KRTAP5-5 | 5 (8%) | 59 | 0.362 (1.00) | 1 (1.00) | 0.219 (1.00) | 0.216 (1.00) | 0.444 (1.00) | 0.18 (1.00) | 0.593 (1.00) | 0.056 (1.00)
AKAP2 | 4 (6%) | 60 | 0.0745 (1.00) | 0.475 (1.00) | 0.738 (1.00) | 0.316 (1.00) | 0.673 (1.00) | 0.468 (1.00) | 0.341 (1.00) | 0.647 (1.00)
KBTBD13 | 9 (14%) | 55 | 0.584 (1.00) | 0.107 (1.00) | 0.734 (1.00) | 0.135 (1.00) | 1 (1.00) | 0.358 (1.00) | 1 (1.00) | 0.78 (1.00)
SPIRE2 | 3 (5%) | 61 | 0.302 (1.00) | 0.0267 (1.00) | 1 (1.00) | 0.824 (1.00) | 1 (1.00) | 0.708 (1.00) | 1 (1.00) | 0.875 (1.00)
NPTX1 | 3 (5%) | 61 | 0.337 (1.00) | 1 (1.00) | 1 (1.00) | 0.825 (1.00) | 0.587 (1.00) | 0.708 (1.00) | 0.43 (1.00) | 0.657 (1.00)
ADAD2 | 4 (6%) | 60 | 0.251 (1.00) | 0.574 (1.00) | 0.738 (1.00) | 0.317 (1.00) | 0.0206 (1.00) | 0.54 (1.00) | 0.0196 (1.00) | 0.837 (1.00)
SEZ6L2 | 8 (12%) | 56 | 0.355 (1.00) | 0.598 (1.00) | 0.882 (1.00) | 1 (1.00) | 0.459 (1.00) | 0.584 (1.00) | 0.456 (1.00) | 0.808 (1.00)
NEFH | 7 (11%) | 57 | 0.0362 (1.00) | 0.157 (1.00) | 0.0236 (1.00) | 0.00825 (1.00) | 0.168 (1.00) | 0.521 (1.00) | 0.35 (1.00) | 0.158 (1.00)
DLEU7 | 3 (5%) | 61 | 0.568 (1.00) |  |  |  |  |  |  |
AMDHD1 | 11 (17%) | 53 | 0.0266 (1.00) | 0.721 (1.00) | 0.569 (1.00) | 0.185 (1.00) | 0.236 (1.00) | 0.888 (1.00) | 0.0625 (1.00) | 0.954 (1.00)
GLTSCR2 | 5 (8%) | 59 | 0.22 (1.00) | 0.806 (1.00) | 0.264 (1.00) | 0.197 (1.00) | 1 (1.00) | 0.623 (1.00) | 0.251 (1.00) | 0.589 (1.00)
PLEC | 13 (20%) | 51 | 0.612 (1.00) | 0.713 (1.00) | 0.194 (1.00) | 0.681 (1.00) | 0.673 (1.00) | 0.604 (1.00) | 0.396 (1.00) | 0.471 (1.00)
MAP7 | 3 (5%) | 61 | 1 (1.00) | 0.697 (1.00) | 1 (1.00) | 0.825 (1.00) | 0.588 (1.00) | 0.708 (1.00) | 0.429 (1.00) | 0.655 (1.00)
DSPP | 10 (16%) | 54 | 0.928 (1.00) | 0.064 (1.00) | 1 (1.00) | 0.516 (1.00) | 0.515 (1.00) | 0.574 (1.00) | 0.313 (1.00) | 0.33 (1.00)
CRIPAK | 10 (16%) | 54 | 0.201 (1.00) | 0.928 (1.00) | 0.474 (1.00) | 0.836 (1.00) | 0.807 (1.00) | 0.359 (1.00) | 0.719 (1.00) | 0.287 (1.00)
PRKAR1A | 6 (9%) | 58 | 0.487 (1.00) | 1 (1.00) | 0.277 (1.00) | 0.457 (1.00) | 0.0865 (1.00) | 0.564 (1.00) | 0.174 (1.00) | 0.151 (1.00)
CYP4A22 | 4 (6%) | 60 | 0.113 (1.00) | 0.622 (1.00) | 0.163 (1.00) | 0.507 (1.00) | 0.246 (1.00) | 0.207 (1.00) | 0.249 (1.00) | 0.837 (1.00)
NOM1 | 6 (9%) | 58 | 1 (1.00) | 0.233 (1.00) | 0.93 (1.00) | 1 (1.00) | 1 (1.00) | 0.742 (1.00) | 0.84 (1.00) | 0.276 (1.00)
RNF135 | 3 (5%) | 61 | 0.894 (1.00) |  |  |  |  |  |  |
C12ORF65 | 3 (5%) | 61 | 0.371 (1.00) | 0.0354 (1.00) | 0.113 (1.00) | 0.0623 (1.00) | 0.445 (1.00) | 0.563 (1.00) | 0.593 (1.00) | 0.735 (1.00)
HLA-B | 6 (9%) | 58 | 0.293 (1.00) | 0.775 (1.00) | 0.883 (1.00) | 1 (1.00) | 0.653 (1.00) | 0.274 (1.00) | 0.535 (1.00) | 0.319 (1.00)
CSGALNACT2 | 3 (5%) | 61 | 0.895 (1.00) | 0.0256 (1.00) | 0.691 (1.00) | 0.823 (1.00) | 0.584 (1.00) | 0.876 (1.00) | 0.43 (1.00) | 0.933 (1.00)
UQCRFS1 | 5 (8%) | 59 | 0.508 (1.00) | 0.502 (1.00) | 1 (1.00) | 0.885 (1.00) | 0.49 (1.00) | 0.187 (1.00) | 0.494 (1.00) | 0.0508 (1.00)
PDCD6 | 3 (5%) | 61 | 0.302 (1.00) | 0.699 (1.00) |  |  | 1 (1.00) | 0.632 (1.00) | 1 (1.00) | 0.696 (1.00)
PTX4 | 3 (5%) | 61 | 0.568 (1.00) | 1 (1.00) | 0.612 (1.00) | 0.217 (1.00) | 0.444 (1.00) | 1 (1.00) | 0.595 (1.00) | 0.392 (1.00)
SGK223 | 3 (5%) | 61 | 0.895 (1.00) |  |  |  |  |  |  |
POLRMT | 4 (6%) | 60 | 0.508 (1.00) | 0.0363 (1.00) | 0.327 (1.00) | 0.0737 (1.00) | 0.189 (1.00) | 0.353 (1.00) | 0.125 (1.00) | 0.443 (1.00)
CACNA1D | 3 (5%) | 61 | 0.566 (1.00) |  |  |  |  |  |  |
NF1 | 7 (11%) | 57 | 0.152 (1.00) | 0.904 (1.00) | 0.41 (1.00) | 0.268 (1.00) | 0.342 (1.00) | 0.853 (1.00) | 0.0999 (1.00) | 0.527 (1.00)
RGMB | 6 (9%) | 58 | 0.581 (1.00) |  |  |  |  |  |  |
ADAMTS7 | 4 (6%) | 60 | 0.14 (1.00) | 0.575 (1.00) | 0.0732 (1.00) | 0.465 (1.00) | 0.061 (1.00) | 0.351 (1.00) | 0.038 (1.00) | 0.288 (1.00)
CLIC6 | 6 (9%) | 58 | 0.962 (1.00) | 1 (1.00) | 0.665 (1.00) | 0.193 (1.00) | 0.246 (1.00) | 0.579 (1.00) | 0.248 (1.00) | 0.759 (1.00)
EMR2 | 4 (6%) | 60 | 0.375 (1.00) | 0.314 (1.00) | 0.473 (1.00) | 0.614 (1.00) | 0.674 (1.00) | 0.207 (1.00) | 0.676 (1.00) | 0.839 (1.00)
PCDHB13 | 5 (8%) | 59 | 0.513 (1.00) | 0.139 (1.00) | 0.107 (1.00) | 0.256 (1.00) | 0.542 (1.00) | 0.0566 (1.00) | 0.801 (1.00) | 0.0126 (1.00)
MTFMT | 3 (5%) | 61 | 1 (1.00) |  |  |  |  |  |  |
SPTAN1 | 3 (5%) | 61 | 0.244 (1.00) |  |  |  |  |  |  |
HLA-A | 3 (5%) | 61 | 1 (1.00) | 1 (1.00) | 0.854 (1.00) | 0.219 (1.00) | 1 (1.00) | 0.445 (1.00) | 1 (1.00) | 0.215 (1.00)
ASB16 | 6 (9%) | 58 | 0.743 (1.00) | 0.945 (1.00) | 0.614 (1.00) | 0.885 (1.00) | 0.543 (1.00) | 0.778 (1.00) | 0.802 (1.00) | 0.959 (1.00)
GPRIN2 | 9 (14%) | 55 | 0.591 (1.00) | 0.37 (1.00) | 0.65 (1.00) | 0.428 (1.00) | 0.582 (1.00) | 0.801 (1.00) | 0.381 (1.00) | 0.647 (1.00)
HNRNPCL1 | 3 (5%) | 61 | 0.336 (1.00) |  |  |  |  |  |  |
BTNL9 | 4 (6%) | 60 | 0.416 (1.00) | 0.0962 (1.00) | 0.141 (1.00) | 0.0618 (1.00) | 0.142 (1.00) | 1 (1.00) | 0.209 (1.00) | 1 (1.00)
KCNJ11 | 4 (6%) | 60 | 0.0135 (1.00) | 0.624 (1.00) | 0.434 (1.00) | 0.14 (1.00) | 0.132 (1.00) | 0.0498 (1.00) | 0.174 (1.00) | 0.211 (1.00)
JMJD4 | 3 (5%) | 61 | 0.8 (1.00) |  |  |  |  |  |  |
LRRC4B | 6 (9%) | 58 | 0.188 (1.00) | 0.189 (1.00) | 0.0133 (1.00) | 0.0708 (1.00) | 0.174 (1.00) | 0.0299 (1.00) | 0.172 (1.00) | 0.00974 (1.00)
OPLAH | 3 (5%) | 61 | 0.566 (1.00) | 0.854 (1.00) | 0.608 (1.00) | 0.472 (1.00) | 0.443 (1.00) | 0.342 (1.00) | 0.594 (1.00) | 0.394 (1.00)
BAGE2 | 3 (5%) | 61 | 0.895 (1.00) |  |  |  |  |  |  |
MADCAM1 | 3 (5%) | 61 | 0.481 (1.00) | 0.696 (1.00) |  |  | 1 (1.00) | 0.199 (1.00) | 1 (1.00) | 0.136 (1.00)
CTBP2 | 3 (5%) | 61 | 0.895 (1.00) |  |  |  |  |  |  |
MSH3 | 4 (6%) | 60 | 0.0176 (1.00) | 0.7 (1.00) | 0.335 (1.00) | 1 (1.00) | 0.3 (1.00) | 0.442 (1.00) | 0.314 (1.00) | 0.495 (1.00)
ATN1 | 4 (6%) | 60 | 0.13 (1.00) | 0.853 (1.00) | 0.855 (1.00) | 1 (1.00) | 0.791 (1.00) | 0.79 (1.00) | 1 (1.00) | 0.823 (1.00)
FAM46A | 3 (5%) | 61 | 0.897 (1.00) |  |  |  |  |  |  |
UTS2R | 3 (5%) | 61 | 0.162 (1.00) | 0.699 (1.00) | 0.69 (1.00) | 0.824 (1.00) | 0.586 (1.00) | 0.791 (1.00) | 0.428 (1.00) | 0.823 (1.00)
SMG1 | 3 (5%) | 61 | 0.164 (1.00) | 0.125 (1.00) | 0.143 (1.00) | 0.0621 (1.00) | 0.305 (1.00) | 0.0256 (1.00) | 0.316 (1.00) | 0.188 (1.00)
FUCA1 | 3 (5%) | 61 | 0.404 (1.00) |  |  |  |  |  |  |
FEZ2 | 3 (5%) | 61 | 0.477 (1.00) | 0.348 (1.00) | 0.179 (1.00) | 0.825 (1.00) | 0.209 (1.00) | 0.709 (1.00) | 0.133 (1.00) | 0.658 (1.00)
GLI3 | 5 (8%) | 59 | 0.737 (1.00) | 0.407 (1.00) | 1 (1.00) | 0.885 (1.00) | 0.134 (1.00) | 0.399 (1.00) | 0.176 (1.00) | 0.0919 (1.00)
NOL9 | 4 (6%) | 60 | 0.00202 (1.00) | 1 (1.00) | 1 (1.00) | 1 (1.00) | 0.789 (1.00) | 0.559 (1.00) | 1 (1.00) | 0.733 (1.00)

'ZFPM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S1. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
ZFPM1 MUTATED | 10 | 7 | 2 | 6 | 1
ZFPM1 WILD-TYPE | 11 | 12 | 6 | 2 | 5

'ZFPM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S2. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
ZFPM1 MUTATED | 6 | 4 | 4 | 6 | 2
ZFPM1 WILD-TYPE | 7 | 4 | 10 | 8 | 5

'ZFPM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.335 (Fisher's exact test), Q value = 1

Table S3. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
ZFPM1 MUTATED | 8 | 1 | 7 | 6
ZFPM1 WILD-TYPE | 9 | 7 | 7 | 10

'ZFPM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S4. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
ZFPM1 MUTATED | 8 | 6 | 2 | 6
ZFPM1 WILD-TYPE | 8 | 10 | 3 | 12

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.68 (Fisher's exact test), Q value = 1

Table S5. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
ZFPM1 MUTATED | 10 | 6 | 6
ZFPM1 WILD-TYPE | 16 | 6 | 12

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S6. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
ZFPM1 MUTATED | 5 | 9 | 2 | 5 | 1
ZFPM1 WILD-TYPE | 8 | 10 | 6 | 9 | 1

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.492 (Fisher's exact test), Q value = 1

Table S7. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
ZFPM1 MUTATED | 10 | 7 | 5
ZFPM1 WILD-TYPE | 17 | 6 | 11

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.938 (Fisher's exact test), Q value = 1

Table S8. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
ZFPM1 MUTATED | 4 | 7 | 2 | 5 | 3 | 1
ZFPM1 WILD-TYPE | 5 | 10 | 5 | 7 | 3 | 4

'LACTB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.117 (Fisher's exact test), Q value = 1

Table S9. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
LACTB MUTATED | 5 | 5 | 2 | 6 | 2
LACTB WILD-TYPE | 16 | 14 | 6 | 2 | 4

'LACTB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S10. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
LACTB MUTATED | 2 | 3 | 5 | 4 | 3
LACTB WILD-TYPE | 11 | 5 | 9 | 10 | 4

'LACTB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S11. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
LACTB MUTATED | 5 | 2 | 5 | 5
LACTB WILD-TYPE | 12 | 6 | 9 | 11

'LACTB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.56 (Fisher's exact test), Q value = 1

Table S12. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
LACTB MUTATED | 4 | 5 | 3 | 5
LACTB WILD-TYPE | 12 | 11 | 2 | 13

'LACTB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S13. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
LACTB MUTATED | 6 | 5 | 6
LACTB WILD-TYPE | 20 | 7 | 12

'LACTB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S14. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
LACTB MUTATED | 4 | 5 | 4 | 4 | 0
LACTB WILD-TYPE | 9 | 14 | 4 | 10 | 2

'LACTB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S15. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
LACTB MUTATED | 6 | 6 | 5
LACTB WILD-TYPE | 21 | 7 | 11

'LACTB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.756 (Fisher's exact test), Q value = 1

Table S16. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
LACTB MUTATED | 3 | 4 | 2 | 3 | 2 | 3
LACTB WILD-TYPE | 6 | 13 | 5 | 9 | 4 | 2

'CCDC102A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.131 (Fisher's exact test), Q value = 1

Table S17. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
CCDC102A MUTATED | 4 | 7 | 0 | 3 | 3
CCDC102A WILD-TYPE | 17 | 12 | 8 | 5 | 3

'CCDC102A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S18. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
CCDC102A MUTATED | 3 | 2 | 4 | 4 | 3
CCDC102A WILD-TYPE | 10 | 6 | 10 | 10 | 4

'CCDC102A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.911 (Fisher's exact test), Q value = 1

Table S19. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
CCDC102A MUTATED | 4 | 3 | 4 | 5
CCDC102A WILD-TYPE | 13 | 5 | 10 | 11

'CCDC102A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S20. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
CCDC102A MUTATED | 4 | 4 | 1 | 7
CCDC102A WILD-TYPE | 12 | 12 | 4 | 11

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S21. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
CCDC102A MUTATED | 7 | 2 | 7
CCDC102A WILD-TYPE | 19 | 10 | 11

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S22. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
CCDC102A MUTATED | 2 | 6 | 4 | 4 | 0
CCDC102A WILD-TYPE | 11 | 13 | 4 | 10 | 2

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S23. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
CCDC102A MUTATED | 7 | 3 | 6
CCDC102A WILD-TYPE | 20 | 10 | 10

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.145 (Fisher's exact test), Q value = 1

Table S24. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
CCDC102A MUTATED | 0 | 6 | 3 | 3 | 1 | 3
CCDC102A WILD-TYPE | 9 | 11 | 4 | 9 | 5 | 2

'ZNF517 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S25. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
ZNF517 MUTATED | 5 | 5 | 0 | 2 | 1
ZNF517 WILD-TYPE | 16 | 14 | 8 | 6 | 5

'ZNF517 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S26. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
ZNF517 MUTATED | 3 | 1 | 2 | 2 | 1
ZNF517 WILD-TYPE | 10 | 7 | 12 | 12 | 6

'ZNF517 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.884 (Fisher's exact test), Q value = 1

Table S27. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
ZNF517 MUTATED | 4 | 1 | 2 | 2
ZNF517 WILD-TYPE | 13 | 7 | 12 | 14

'ZNF517 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S28. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
ZNF517 MUTATED | 3 | 2 | 1 | 3
ZNF517 WILD-TYPE | 13 | 14 | 4 | 15

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 1

Table S29. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
ZNF517 MUTATED | 3 | 4 | 2
ZNF517 WILD-TYPE | 23 | 8 | 16

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S30. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
ZNF517 MUTATED | 1 | 3 | 1 | 4 | 0
ZNF517 WILD-TYPE | 12 | 16 | 7 | 10 | 2

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S31. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
ZNF517 MUTATED | 4 | 3 | 2
ZNF517 WILD-TYPE | 23 | 10 | 14

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.427 (Fisher's exact test), Q value = 1

Table S32. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
ZNF517 MUTATED | 0 | 2 | 1 | 4 | 1 | 1
ZNF517 WILD-TYPE | 9 | 15 | 6 | 8 | 5 | 4

'TOR3A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.273 (Fisher's exact test), Q value = 1

Table S33. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
TOR3A MUTATED | 5 | 3 | 0 | 3 | 0
TOR3A WILD-TYPE | 16 | 16 | 8 | 5 | 6

'TOR3A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0221 (Fisher's exact test), Q value = 1

Table S34. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
TOR3A MUTATED | 0 | 0 | 4 | 6 | 1
TOR3A WILD-TYPE | 13 | 8 | 10 | 8 | 6

Figure S1. Get High-res Image Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'TOR3A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S35. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
TOR3A MUTATED | 2 | 1 | 4 | 4
TOR3A WILD-TYPE | 15 | 7 | 10 | 12

'TOR3A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0151 (Fisher's exact test), Q value = 1

Table S36. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
TOR3A MUTATED | 0 | 3 | 3 | 5
TOR3A WILD-TYPE | 16 | 13 | 2 | 13

Figure S2. Get High-res Image Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'TOR3A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S37. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
TOR3A MUTATED | 5 | 2 | 4
TOR3A WILD-TYPE | 21 | 10 | 14

'TOR3A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.868 (Fisher's exact test), Q value = 1

Table S38. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
TOR3A MUTATED | 2 | 5 | 2 | 2 | 0
TOR3A WILD-TYPE | 11 | 14 | 6 | 12 | 2

'TOR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.828 (Fisher's exact test), Q value = 1

Table S39. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
TOR3A MUTATED | 5 | 2 | 4
TOR3A WILD-TYPE | 22 | 11 | 12

'TOR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S40. Gene #5: 'TOR3A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
TOR3A MUTATED | 2 | 4 | 2 | 1 | 2 | 0
TOR3A WILD-TYPE | 7 | 13 | 5 | 11 | 4 | 5

'USP42 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.725 (Fisher's exact test), Q value = 1

Table S41. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
USP42 MUTATED | 5 | 4 | 2 | 2 | 3
USP42 WILD-TYPE | 16 | 15 | 6 | 6 | 3

'USP42 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0487 (Fisher's exact test), Q value = 1

Table S42. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
USP42 MUTATED | 2 | 4 | 0 | 3 | 2
USP42 WILD-TYPE | 11 | 4 | 14 | 11 | 5

Figure S3. Get High-res Image Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'USP42 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S43. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
USP42 MUTATED | 3 | 2 | 3 | 3
USP42 WILD-TYPE | 14 | 6 | 11 | 13

'USP42 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S44. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
USP42 MUTATED | 3 | 4 | 1 | 3
USP42 WILD-TYPE | 13 | 12 | 4 | 15

'USP42 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.567 (Fisher's exact test), Q value = 1

Table S45. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
USP42 MUTATED | 6 | 3 | 2
USP42 WILD-TYPE | 20 | 9 | 16

'USP42 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S46. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
USP42 MUTATED | 2 | 3 | 2 | 4 | 0
USP42 WILD-TYPE | 11 | 16 | 6 | 10 | 2

'USP42 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S47. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
USP42 MUTATED | 6 | 3 | 2
USP42 WILD-TYPE | 21 | 10 | 14

'USP42 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.289 (Fisher's exact test), Q value = 1

Table S48. Gene #6: 'USP42 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
USP42 MUTATED | 1 | 3 | 3 | 4 | 0 | 0
USP42 WILD-TYPE | 8 | 14 | 4 | 8 | 6 | 5

'CLDN23 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.263 (Fisher's exact test), Q value = 1

Table S49. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
CLDN23 MUTATED | 2 | 5 | 1 | 0 | 2
CLDN23 WILD-TYPE | 19 | 14 | 7 | 8 | 4

'CLDN23 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.247 (Fisher's exact test), Q value = 1

Table S50. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
CLDN23 MUTATED | 1 | 2 | 1 | 3 | 3
CLDN23 WILD-TYPE | 12 | 6 | 13 | 11 | 4

'CLDN23 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0237 (Fisher's exact test), Q value = 1

Table S51. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
CLDN23 MUTATED | 1 | 1 | 1 | 7
CLDN23 WILD-TYPE | 16 | 7 | 13 | 9

Figure S4. Get High-res Image Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'CLDN23 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S52. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
CLDN23 MUTATED | 3 | 1 | 0 | 6
CLDN23 WILD-TYPE | 13 | 15 | 5 | 12

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0905 (Fisher's exact test), Q value = 1

Table S53. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
CLDN23 MUTATED | 2 | 2 | 6
CLDN23 WILD-TYPE | 24 | 10 | 12

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.19 (Fisher's exact test), Q value = 1

Table S54. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
CLDN23 MUTATED | 1 | 4 | 3 | 1 | 1
CLDN23 WILD-TYPE | 12 | 15 | 5 | 13 | 1

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.108 (Fisher's exact test), Q value = 1

Table S55. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
CLDN23 MUTATED | 2 | 3 | 5
CLDN23 WILD-TYPE | 25 | 10 | 11

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.322 (Fisher's exact test), Q value = 1

Table S56. Gene #7: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
CLDN23 MUTATED | 0 | 4 | 2 | 1 | 1 | 2
CLDN23 WILD-TYPE | 9 | 13 | 5 | 11 | 5 | 3

'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0216 (Fisher's exact test), Q value = 1

Table S57. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
TP53 MUTATED | 4 | 1 | 2 | 5 | 1
TP53 WILD-TYPE | 17 | 18 | 6 | 3 | 5

Figure S5. Get High-res Image Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S58. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
TP53 MUTATED | 2 | 3 | 3 | 2 | 1
TP53 WILD-TYPE | 11 | 5 | 11 | 12 | 6

'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0201 (Fisher's exact test), Q value = 1

Table S59. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
TP53 MUTATED | 3 | 2 | 6 | 0
TP53 WILD-TYPE | 14 | 6 | 8 | 16

Figure S6. Get High-res Image Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.666 (Fisher's exact test), Q value = 1

Table S60. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
TP53 MUTATED | 4 | 4 | 1 | 2
TP53 WILD-TYPE | 12 | 12 | 4 | 16

'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.018 (Fisher's exact test), Q value = 1

Table S61. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
TP53 MUTATED | 7 | 4 | 0
TP53 WILD-TYPE | 19 | 8 | 18

Figure S7. Get High-res Image Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S62. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
TP53 MUTATED | 4 | 2 | 2 | 3 | 0
TP53 WILD-TYPE | 9 | 17 | 6 | 11 | 2

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0416 (Fisher's exact test), Q value = 1

Table S63. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
TP53 MUTATED | 7 | 4 | 0
TP53 WILD-TYPE | 20 | 9 | 16

Figure S8. Get High-res Image Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.192 (Fisher's exact test), Q value = 1

Table S64. Gene #8: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
TP53 MUTATED | 3 | 1 | 3 | 3 | 1 | 0
TP53 WILD-TYPE | 6 | 16 | 4 | 9 | 5 | 5

'KCNK17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.103 (Fisher's exact test), Q value = 1

Table S65. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
KCNK17 MUTATED | 2 | 1 | 1 | 3 | 2
KCNK17 WILD-TYPE | 19 | 18 | 7 | 5 | 4

'KCNK17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0379 (Fisher's exact test), Q value = 1

Table S66. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
KCNK17 MUTATED | 0 | 2 | 5 | 1 | 0
KCNK17 WILD-TYPE | 13 | 6 | 9 | 13 | 7

Figure S9. Get High-res Image Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'KCNK17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0944 (Fisher's exact test), Q value = 1

Table S67. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
KCNK17 MUTATED | 1 | 1 | 5 | 1
KCNK17 WILD-TYPE | 16 | 7 | 9 | 15

'KCNK17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00996 (Fisher's exact test), Q value = 1

Table S68. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
KCNK17 MUTATED | 0 | 6 | 1 | 1
KCNK17 WILD-TYPE | 16 | 10 | 4 | 17

Figure S10. Get High-res Image Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S69. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
KCNK17 MUTATED | 4 | 2 | 2
KCNK17 WILD-TYPE | 22 | 10 | 16

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S70. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
KCNK17 MUTATED | 3 | 1 | 2 | 2 | 0
KCNK17 WILD-TYPE | 10 | 18 | 6 | 12 | 2

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S71. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
KCNK17 MUTATED | 4 | 3 | 1
KCNK17 WILD-TYPE | 23 | 10 | 15

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S72. Gene #9: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
KCNK17 MUTATED | 3 | 1 | 1 | 2 | 0 | 1
KCNK17 WILD-TYPE | 6 | 16 | 6 | 10 | 6 | 4

'LZTR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 1

Table S73. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
LZTR1 MUTATED | 4 | 0 | 1 | 1 | 0
LZTR1 WILD-TYPE | 17 | 19 | 7 | 7 | 6

'LZTR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.806 (Fisher's exact test), Q value = 1

Table S74. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
LZTR1 MUTATED | 2 | 0 | 1 | 1 | 0
LZTR1 WILD-TYPE | 11 | 8 | 13 | 13 | 7

'LZTR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0894 (Fisher's exact test), Q value = 1

Table S75. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
LZTR1 MUTATED | 3 | 1 | 0 | 0
LZTR1 WILD-TYPE | 14 | 7 | 14 | 16

'LZTR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.194 (Fisher's exact test), Q value = 1

Table S76. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
LZTR1 MUTATED | 2 | 1 | 1 | 0
LZTR1 WILD-TYPE | 14 | 15 | 4 | 18

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S77. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
LZTR1 MUTATED | 3 | 1 | 0
LZTR1 WILD-TYPE | 23 | 11 | 18

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0137 (Fisher's exact test), Q value = 1

Table S78. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
LZTR1 MUTATED | 0 | 0 | 0 | 3 | 1
LZTR1 WILD-TYPE | 13 | 19 | 8 | 11 | 1

Figure S11. Get High-res Image Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S79. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
LZTR1 MUTATED | 3 | 1 | 0
LZTR1 WILD-TYPE | 24 | 12 | 16

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0854 (Fisher's exact test), Q value = 1

Table S80. Gene #10: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
LZTR1 MUTATED | 0 | 0 | 0 | 3 | 1 | 0
LZTR1 WILD-TYPE | 9 | 17 | 7 | 9 | 5 | 5

'APOE MUTATION STATUS' versus 'CN_CNMF'

P value = 0.17 (Fisher's exact test), Q value = 1

Table S81. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
APOE MUTATED | 1 | 2 | 1 | 3 | 0
APOE WILD-TYPE | 20 | 17 | 7 | 5 | 6

'APOE MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.62 (Fisher's exact test), Q value = 1

Table S82. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
APOE MUTATED | 1 | 0 | 3 | 2 | 0
APOE WILD-TYPE | 12 | 8 | 11 | 12 | 7

'APOE MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0669 (Fisher's exact test), Q value = 1

Table S83. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
APOE MUTATED | 2 | 0 | 4 | 0
APOE WILD-TYPE | 15 | 8 | 10 | 16

'APOE MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S84. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
APOE MUTATED | 1 | 3 | 1 | 1
APOE WILD-TYPE | 15 | 13 | 4 | 17

'APOE MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 1

Table S85. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
APOE MUTATED | 2 | 3 | 1
APOE WILD-TYPE | 24 | 9 | 17

'APOE MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S86. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
APOE MUTATED | 1 | 3 | 0 | 2 | 0
APOE WILD-TYPE | 12 | 16 | 8 | 12 | 2

'APOE MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.027 (Fisher's exact test), Q value = 1

Table S87. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
APOE MUTATED | 2 | 4 | 0
APOE WILD-TYPE | 25 | 9 | 16

Figure S12. Get High-res Image Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'APOE MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S88. Gene #11: 'APOE MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
APOE MUTATED | 0 | 2 | 1 | 2 | 1 | 0
APOE WILD-TYPE | 9 | 15 | 6 | 10 | 5 | 5

'CCDC105 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.169 (Fisher's exact test), Q value = 1

Table S89. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
CCDC105 MUTATED | 1 | 2 | 1 | 3 | 0
CCDC105 WILD-TYPE | 20 | 17 | 7 | 5 | 6

'CCDC105 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00859 (Fisher's exact test), Q value = 1

Table S90. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
CCDC105 MUTATED | 1 | 3 | 0 | 0 | 2
CCDC105 WILD-TYPE | 12 | 5 | 14 | 14 | 5

Figure S13. Get High-res Image Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CCDC105 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S91. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
CCDC105 MUTATED | 1 | 1 | 2 | 2
CCDC105 WILD-TYPE | 16 | 7 | 12 | 14

'CCDC105 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.714 (Fisher's exact test), Q value = 1

Table S92. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
CCDC105 MUTATED | 3 | 1 | 0 | 2
CCDC105 WILD-TYPE | 13 | 15 | 5 | 16

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S93. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
CCDC105 MUTATED | 3 | 1 | 2
CCDC105 WILD-TYPE | 23 | 11 | 16

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0509 (Fisher's exact test), Q value = 1

Table S94. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
CCDC105 MUTATED | 1 | 0 | 2 | 2 | 1
CCDC105 WILD-TYPE | 12 | 19 | 6 | 12 | 1

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S95. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
CCDC105 MUTATED | 3 | 2 | 1
CCDC105 WILD-TYPE | 24 | 11 | 15

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.326 (Fisher's exact test), Q value = 1

Table S96. Gene #12: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
CCDC105 MUTATED | 1 | 0 | 1 | 2 | 1 | 1
CCDC105 WILD-TYPE | 8 | 17 | 6 | 10 | 5 | 4

'RINL MUTATION STATUS' versus 'CN_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 1

Table S97. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
RINL MUTATED | 6 | 1 | 0 | 1 | 0
RINL WILD-TYPE | 15 | 18 | 8 | 7 | 6

'RINL MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.701 (Fisher's exact test), Q value = 1

Table S98. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
RINL MUTATED | 3 | 1 | 1 | 2 | 0
RINL WILD-TYPE | 10 | 7 | 13 | 12 | 7

'RINL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S99. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
RINL MUTATED | 4 | 1 | 1 | 1
RINL WILD-TYPE | 13 | 7 | 13 | 15

'RINL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.294 (Fisher's exact test), Q value = 1

Table S100. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
RINL MUTATED | 4 | 1 | 1 | 1
RINL WILD-TYPE | 12 | 15 | 4 | 17

'RINL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S101. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
RINL MUTATED | 3 | 2 | 2
RINL WILD-TYPE | 23 | 10 | 16

'RINL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.166 (Fisher's exact test), Q value = 1

Table S102. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
RINL MUTATED | 0 | 3 | 0 | 4 | 0
RINL WILD-TYPE | 13 | 16 | 8 | 10 | 2

'RINL MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S103. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
RINL MUTATED | 3 | 3 | 1
RINL WILD-TYPE | 24 | 10 | 15

'RINL MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.187 (Fisher's exact test), Q value = 1

Table S104. Gene #13: 'RINL MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
RINL MUTATED | 0 | 3 | 0 | 4 | 0 | 0
RINL WILD-TYPE | 9 | 14 | 7 | 8 | 6 | 5

'MAL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S105. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
MAL2 MUTATED | 4 | 5 | 2 | 1 | 0
MAL2 WILD-TYPE | 17 | 14 | 6 | 7 | 6

'MAL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S106. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
MAL2 MUTATED | 3 | 2 | 0 | 3 | 1
MAL2 WILD-TYPE | 10 | 6 | 14 | 11 | 6

'MAL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S107. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
MAL2 MUTATED | 4 | 2 | 0 | 3
MAL2 WILD-TYPE | 13 | 6 | 14 | 13

'MAL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.518 (Fisher's exact test), Q value = 1

Table S108. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
MAL2 MUTATED | 4 | 1 | 1 | 3
MAL2 WILD-TYPE | 12 | 15 | 4 | 15

'MAL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.123 (Fisher's exact test), Q value = 1

Table S109. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
MAL2 MUTATED | 2 | 4 | 3
MAL2 WILD-TYPE | 24 | 8 | 15

'MAL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.277 (Fisher's exact test), Q value = 1

Table S110. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
MAL2 MUTATED | 0 | 4 | 1 | 4 | 0
MAL2 WILD-TYPE | 13 | 15 | 7 | 10 | 2

'MAL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S111. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
MAL2 MUTATED | 3 | 3 | 3
MAL2 WILD-TYPE | 24 | 10 | 13

'MAL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.321 (Fisher's exact test), Q value = 1

Table S112. Gene #14: 'MAL2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
MAL2 MUTATED | 0 | 3 | 0 | 4 | 1 | 1
MAL2 WILD-TYPE | 9 | 14 | 7 | 8 | 5 | 4

'LRIG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.654 (Fisher's exact test), Q value = 1

Table S113. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
LRIG1 MUTATED | 5 | 4 | 3 | 2 | 3
LRIG1 WILD-TYPE | 16 | 15 | 5 | 6 | 3

'LRIG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S114. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
LRIG1 MUTATED | 3 | 2 | 2 | 4 | 1
LRIG1 WILD-TYPE | 10 | 6 | 12 | 10 | 6

'LRIG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S115. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
LRIG1 MUTATED | 3 | 2 | 3 | 3
LRIG1 WILD-TYPE | 14 | 6 | 11 | 13

'LRIG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S116. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
LRIG1 MUTATED | 3 | 2 | 1 | 5
LRIG1 WILD-TYPE | 13 | 14 | 4 | 13

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 1

Table S117. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
LRIG1 MUTATED | 4 | 5 | 3
LRIG1 WILD-TYPE | 22 | 7 | 15

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.496 (Fisher's exact test), Q value = 1

Table S118. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
LRIG1 MUTATED | 1 | 4 | 3 | 4 | 0
LRIG1 WILD-TYPE | 12 | 15 | 5 | 10 | 2

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S119. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
LRIG1 MUTATED | 5 | 4 | 3
LRIG1 WILD-TYPE | 22 | 9 | 13

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S120. Gene #15: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
LRIG1 MUTATED | 1 | 3 | 2 | 4 | 1 | 1
LRIG1 WILD-TYPE | 8 | 14 | 5 | 8 | 5 | 4

'C19ORF10 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.633 (Fisher's exact test), Q value = 1

Table S121. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
C19ORF10 MUTATED | 3 | 2 | 0 | 2 | 0
C19ORF10 WILD-TYPE | 18 | 17 | 8 | 6 | 6

'C19ORF10 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S122. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
C19ORF10 MUTATED | 2 | 1 | 3 | 0 | 0
C19ORF10 WILD-TYPE | 11 | 7 | 11 | 14 | 7

'C19ORF10 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.235 (Fisher's exact test), Q value = 1

Table S123. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
C19ORF10 MUTATED | 2 | 2 | 2 | 0
C19ORF10 WILD-TYPE | 15 | 6 | 12 | 16

'C19ORF10 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.109 (Fisher's exact test), Q value = 1

Table S124. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
C19ORF10 MUTATED | 2 | 4 | 0 | 0
C19ORF10 WILD-TYPE | 14 | 12 | 5 | 18

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.55 (Fisher's exact test), Q value = 1

Table S125. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
C19ORF10 MUTATED | 3 | 2 | 1
C19ORF10 WILD-TYPE | 23 | 10 | 17

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.86 (Fisher's exact test), Q value = 1

Table S126. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
C19ORF10 MUTATED | 2 | 2 | 0 | 2 | 0
C19ORF10 WILD-TYPE | 11 | 17 | 8 | 12 | 2

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.287 (Fisher's exact test), Q value = 1

Table S127. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
C19ORF10 MUTATED | 4 | 2 | 0
C19ORF10 WILD-TYPE | 23 | 11 | 16

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S128. Gene #16: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
C19ORF10 MUTATED | 2 | 2 | 0 | 2 | 0 | 0
C19ORF10 WILD-TYPE | 7 | 15 | 7 | 10 | 6 | 5

'C10ORF95 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S129. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
C10ORF95 MUTATED | 2 | 0 | 2 | 1 | 1
C10ORF95 WILD-TYPE | 19 | 19 | 6 | 7 | 5

'C10ORF95 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.707 (Fisher's exact test), Q value = 1

Table S130. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
C10ORF95 MUTATED | 1 | 0 | 3 | 1 | 1
C10ORF95 WILD-TYPE | 12 | 8 | 11 | 13 | 6

'C10ORF95 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.557 (Fisher's exact test), Q value = 1

Table S131. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
C10ORF95 MUTATED | 2 | 2 | 1 | 1
C10ORF95 WILD-TYPE | 15 | 6 | 13 | 15

'C10ORF95 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S132. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
C10ORF95 MUTATED | 1 | 2 | 1 | 2
C10ORF95 WILD-TYPE | 15 | 14 | 4 | 16

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.75 (Fisher's exact test), Q value = 1

Table S133. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
C10ORF95 MUTATED | 4 | 1 | 1
C10ORF95 WILD-TYPE | 22 | 11 | 17

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S134. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
C10ORF95 MUTATED | 1 | 2 | 1 | 1 | 1
C10ORF95 WILD-TYPE | 12 | 17 | 7 | 13 | 1

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S135. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
C10ORF95 MUTATED | 4 | 1 | 1
C10ORF95 WILD-TYPE | 23 | 12 | 15

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S136. Gene #17: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
C10ORF95 MUTATED | 1 | 1 | 1 | 1 | 2 | 0
C10ORF95 WILD-TYPE | 8 | 16 | 6 | 11 | 4 | 5

'SYT8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S137. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
SYT8 MUTATED | 1 | 4 | 2 | 1 | 1
SYT8 WILD-TYPE | 20 | 15 | 6 | 7 | 5

'SYT8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S138. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
SYT8 MUTATED | 0 | 2 | 2 | 1 | 1
SYT8 WILD-TYPE | 13 | 6 | 12 | 13 | 6

'SYT8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0346 (Fisher's exact test), Q value = 1

Table S139. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
SYT8 MUTATED | 0 | 3 | 1 | 2
SYT8 WILD-TYPE | 17 | 5 | 13 | 14

Figure S14. Get High-res Image Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'SYT8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.147 (Fisher's exact test), Q value = 1

Table S140. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
SYT8 MUTATED | 0 | 4 | 0 | 2
SYT8 WILD-TYPE | 16 | 12 | 5 | 16

'SYT8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S141. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
SYT8 MUTATED | 3 | 1 | 2
SYT8 WILD-TYPE | 23 | 11 | 16

'SYT8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.216 (Fisher's exact test), Q value = 1

Table S142. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
SYT8 MUTATED | 1 | 3 | 1 | 0 | 1
SYT8 WILD-TYPE | 12 | 16 | 7 | 14 | 1

'SYT8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S143. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
SYT8 MUTATED | 3 | 1 | 2
SYT8 WILD-TYPE | 24 | 12 | 14

'SYT8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.643 (Fisher's exact test), Q value = 1

Table S144. Gene #18: 'SYT8 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
SYT8 MUTATED | 1 | 3 | 1 | 0 | 1 | 0
SYT8 WILD-TYPE | 8 | 14 | 6 | 12 | 5 | 5

'IDUA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S145. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
IDUA MUTATED | 4 | 1 | 1 | 2 | 1
IDUA WILD-TYPE | 17 | 18 | 7 | 6 | 5

'IDUA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S146. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
IDUA MUTATED | 2 | 1 | 3 | 2 | 0
IDUA WILD-TYPE | 11 | 7 | 11 | 12 | 7

'IDUA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.345 (Fisher's exact test), Q value = 1

Table S147. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
IDUA MUTATED | 4 | 2 | 1 | 1
IDUA WILD-TYPE | 13 | 6 | 13 | 15

'IDUA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S148. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
IDUA MUTATED | 3 | 3 | 1 | 1
IDUA WILD-TYPE | 13 | 13 | 4 | 17

'IDUA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.122 (Fisher's exact test), Q value = 1

Table S149. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
IDUA MUTATED | 3 | 4 | 1
IDUA WILD-TYPE | 23 | 8 | 17

'IDUA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S150. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
IDUA MUTATED | 1 | 3 | 0 | 4 | 0
IDUA WILD-TYPE | 12 | 16 | 8 | 10 | 2

'IDUA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.196 (Fisher's exact test), Q value = 1

Table S151. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
IDUA MUTATED | 3 | 4 | 1
IDUA WILD-TYPE | 24 | 9 | 15

'IDUA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S152. Gene #19: 'IDUA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
IDUA MUTATED | 1 | 2 | 0 | 3 | 2 | 0
IDUA WILD-TYPE | 8 | 15 | 7 | 9 | 4 | 5

'HHIPL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 1

Table S153. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
HHIPL1 MUTATED | 4 | 1 | 0 | 3 | 0
HHIPL1 WILD-TYPE | 17 | 18 | 8 | 5 | 6

'HHIPL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 1

Table S154. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
HHIPL1 MUTATED | 2 | 0 | 0 | 3 | 1
HHIPL1 WILD-TYPE | 11 | 8 | 14 | 11 | 6

'HHIPL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.358 (Fisher's exact test), Q value = 1

Table S155. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
HHIPL1 MUTATED | 4 | 0 | 1 | 1
HHIPL1 WILD-TYPE | 13 | 8 | 13 | 15

'HHIPL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 1

Table S156. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
HHIPL1 MUTATED | 2 | 1 | 2 | 1
HHIPL1 WILD-TYPE | 14 | 15 | 3 | 17

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 1

Table S157. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
HHIPL1 MUTATED | 4 | 2 | 0
HHIPL1 WILD-TYPE | 22 | 10 | 18

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S158. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
HHIPL1 MUTATED | 2 | 1 | 1 | 2 | 0
HHIPL1 WILD-TYPE | 11 | 18 | 7 | 12 | 2

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.289 (Fisher's exact test), Q value = 1

Table S159. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
HHIPL1 MUTATED | 4 | 2 | 0
HHIPL1 WILD-TYPE | 23 | 11 | 16

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.201 (Fisher's exact test), Q value = 1

Table S160. Gene #20: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
HHIPL1 MUTATED | 1 | 0 | 2 | 2 | 1 | 0
HHIPL1 WILD-TYPE | 8 | 17 | 5 | 10 | 5 | 5

'ASPDH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 1

Table S161. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
ASPDH MUTATED | 2 | 2 | 1 | 3 | 0
ASPDH WILD-TYPE | 19 | 17 | 7 | 5 | 6

'ASPDH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S162. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
ASPDH MUTATED | 3 | 1 | 3 | 1 | 0
ASPDH WILD-TYPE | 10 | 7 | 11 | 13 | 7

'ASPDH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0203 (Fisher's exact test), Q value = 1

Table S163. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
ASPDH MUTATED | 3 | 0 | 5 | 0
ASPDH WILD-TYPE | 14 | 8 | 9 | 16

Figure S15. Get High-res Image Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'ASPDH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.344 (Fisher's exact test), Q value = 1

Table S164. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
ASPDH MUTATED | 3 | 4 | 0 | 1
ASPDH WILD-TYPE | 13 | 12 | 5 | 17

'ASPDH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S165. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
ASPDH MUTATED | 5 | 2 | 1
ASPDH WILD-TYPE | 21 | 10 | 17

'ASPDH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0277 (Fisher's exact test), Q value = 1

Table S166. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
ASPDH MUTATED | 4 | 0 | 0 | 4 | 0
ASPDH WILD-TYPE | 9 | 19 | 8 | 10 | 2

Figure S16. Get High-res Image Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'ASPDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.368 (Fisher's exact test), Q value = 1

Table S167. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
ASPDH MUTATED | 6 | 1 | 1
ASPDH WILD-TYPE | 21 | 12 | 15

'ASPDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0793 (Fisher's exact test), Q value = 1

Table S168. Gene #21: 'ASPDH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
ASPDH MUTATED | 2 | 0 | 1 | 4 | 0 | 1
ASPDH WILD-TYPE | 7 | 17 | 6 | 8 | 6 | 4

'C1ORF106 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S169. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
C1ORF106 MUTATED | 4 | 2 | 2 | 1 | 0
C1ORF106 WILD-TYPE | 17 | 17 | 6 | 7 | 6

'C1ORF106 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S170. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
C1ORF106 MUTATED | 3 | 0 | 2 | 1 | 2
C1ORF106 WILD-TYPE | 10 | 8 | 12 | 13 | 5

'C1ORF106 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S171. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
C1ORF106 MUTATED | 4 | 2 | 1 | 1
C1ORF106 WILD-TYPE | 13 | 6 | 13 | 15

'C1ORF106 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S172. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
C1ORF106 MUTATED | 3 | 2 | 1 | 2
C1ORF106 WILD-TYPE | 13 | 14 | 4 | 16

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.478 (Fisher's exact test), Q value = 1

Table S173. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
C1ORF106 MUTATED | 5 | 2 | 1
C1ORF106 WILD-TYPE | 21 | 10 | 17

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.689 (Fisher's exact test), Q value = 1

Table S174. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
C1ORF106 MUTATED | 1 | 2 | 2 | 3 | 0
C1ORF106 WILD-TYPE | 12 | 17 | 6 | 11 | 2

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.616 (Fisher's exact test), Q value = 1

Table S175. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
C1ORF106 MUTATED | 5 | 2 | 1
C1ORF106 WILD-TYPE | 22 | 11 | 15

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S176. Gene #22: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
C1ORF106 MUTATED | 1 | 2 | 1 | 2 | 1 | 1
C1ORF106 WILD-TYPE | 8 | 15 | 6 | 10 | 5 | 4

'THEM4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00358 (Fisher's exact test), Q value = 1

Table S177. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
THEM4 MUTATED | 1 | 0 | 1 | 4 | 0
THEM4 WILD-TYPE | 20 | 19 | 7 | 4 | 6

Figure S17. Get High-res Image Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'THEM4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S178. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
THEM4 MUTATED | 1 | 1 | 1 | 0 | 1
THEM4 WILD-TYPE | 12 | 7 | 13 | 14 | 6

'THEM4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.437 (Fisher's exact test), Q value = 1

Table S179. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
THEM4 MUTATED | 1 | 1 | 2 | 0
THEM4 WILD-TYPE | 16 | 7 | 12 | 16

'THEM4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.886 (Fisher's exact test), Q value = 1

Table S180. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
THEM4 MUTATED | 2 | 1 | 0 | 1
THEM4 WILD-TYPE | 14 | 15 | 5 | 17

'THEM4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.245 (Fisher's exact test), Q value = 1

Table S181. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
THEM4 MUTATED | 2 | 2 | 0
THEM4 WILD-TYPE | 24 | 10 | 18

'THEM4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0938 (Fisher's exact test), Q value = 1

Table S182. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
THEM4 MUTATED | 0 | 0 | 1 | 3 | 0
THEM4 WILD-TYPE | 13 | 19 | 7 | 11 | 2

'THEM4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.25 (Fisher's exact test), Q value = 1

Table S183. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
THEM4 MUTATED | 2 | 2 | 0
THEM4 WILD-TYPE | 25 | 11 | 16

'THEM4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.111 (Fisher's exact test), Q value = 1

Table S184. Gene #23: 'THEM4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
THEM4 MUTATED | 0 | 0 | 1 | 3 | 0 | 0
THEM4 WILD-TYPE | 9 | 17 | 6 | 9 | 6 | 5

'CTNNB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S185. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
CTNNB1 MUTATED | 3 | 2 | 1 | 1 | 0
CTNNB1 WILD-TYPE | 18 | 17 | 7 | 7 | 6

'CTNNB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 1

Table S186. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
CTNNB1 MUTATED | 3 | 2 | 1 | 0 | 0
CTNNB1 WILD-TYPE | 10 | 6 | 13 | 14 | 7

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0194 (Fisher's exact test), Q value = 1

Table S187. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
CTNNB1 MUTATED | 4 | 2 | 0 | 0
CTNNB1 WILD-TYPE | 13 | 6 | 14 | 16

Figure S18. Get High-res Image Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0181 (Fisher's exact test), Q value = 1

Table S188. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
CTNNB1 MUTATED | 5 | 1 | 0 | 0
CTNNB1 WILD-TYPE | 11 | 15 | 5 | 18

Figure S19. Get High-res Image Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00174 (Fisher's exact test), Q value = 1

Table S189. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
CTNNB1 MUTATED | 1 | 5 | 0
CTNNB1 WILD-TYPE | 25 | 7 | 18

Figure S20. Get High-res Image Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.169 (Fisher's exact test), Q value = 1

Table S190. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
CTNNB1 MUTATED | 0 | 2 | 0 | 4 | 0
CTNNB1 WILD-TYPE | 13 | 17 | 8 | 10 | 2

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0272 (Fisher's exact test), Q value = 1

Table S191. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
CTNNB1 MUTATED | 2 | 4 | 0
CTNNB1 WILD-TYPE | 25 | 9 | 16

Figure S21. Get High-res Image Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.48 (Fisher's exact test), Q value = 1

Table S192. Gene #24: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
CTNNB1 MUTATED | 0 | 2 | 0 | 3 | 1 | 0
CTNNB1 WILD-TYPE | 9 | 15 | 7 | 9 | 5 | 5

'GDF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S193. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
GDF1 MUTATED | 1 | 2 | 0 | 2 | 0
GDF1 WILD-TYPE | 20 | 17 | 8 | 6 | 6

'GDF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.312 (Fisher's exact test), Q value = 1

Table S194. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
GDF1 MUTATED | 0 | 0 | 3 | 1 | 0
GDF1 WILD-TYPE | 13 | 8 | 11 | 13 | 7

'GDF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.362 (Fisher's exact test), Q value = 1

Table S195. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
GDF1 MUTATED | 0 | 1 | 2 | 1
GDF1 WILD-TYPE | 17 | 7 | 12 | 15

'GDF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.254 (Fisher's exact test), Q value = 1

Table S196. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
GDF1 MUTATED | 0 | 3 | 0 | 1
GDF1 WILD-TYPE | 16 | 13 | 5 | 17

'GDF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0896 (Fisher's exact test), Q value = 1

Table S197. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
GDF1 MUTATED | 0 | 2 | 2
GDF1 WILD-TYPE | 26 | 10 | 16

'GDF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S198. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
GDF1 MUTATED | 0 | 3 | 0 | 1 | 0
GDF1 WILD-TYPE | 13 | 16 | 8 | 13 | 2

'GDF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0192 (Fisher's exact test), Q value = 1

Table S199. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
GDF1 MUTATED | 0 | 3 | 1
GDF1 WILD-TYPE | 27 | 10 | 15

Figure S22. Get High-res Image Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'GDF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S200. Gene #25: 'GDF1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
GDF1 MUTATED | 0 | 3 | 0 | 1 | 0 | 0
GDF1 WILD-TYPE | 9 | 14 | 7 | 11 | 6 | 5

'TSC22D2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S201. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
TSC22D2 MUTATED | 4 | 1 | 0 | 2 | 1
TSC22D2 WILD-TYPE | 17 | 18 | 8 | 6 | 5

'TSC22D2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S202. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
TSC22D2 MUTATED | 2 | 0 | 2 | 1 | 2
TSC22D2 WILD-TYPE | 11 | 8 | 12 | 13 | 5

'TSC22D2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.815 (Fisher's exact test), Q value = 1

Table S203. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
TSC22D2 MUTATED | 3 | 0 | 2 | 2
TSC22D2 WILD-TYPE | 14 | 8 | 12 | 14

'TSC22D2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.942 (Fisher's exact test), Q value = 1

Table S204. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
TSC22D2 MUTATED | 2 | 2 | 1 | 2
TSC22D2 WILD-TYPE | 14 | 14 | 4 | 16

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S205. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
TSC22D2 MUTATED | 3 | 2 | 2
TSC22D2 WILD-TYPE | 23 | 10 | 16

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.426 (Fisher's exact test), Q value = 1

Table S206. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
TSC22D2 MUTATED | 1 | 2 | 0 | 4 | 0
TSC22D2 WILD-TYPE | 12 | 17 | 8 | 10 | 2

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S207. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
TSC22D2 MUTATED | 3 | 2 | 2
TSC22D2 WILD-TYPE | 24 | 11 | 14

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.334 (Fisher's exact test), Q value = 1

Table S208. Gene #26: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
TSC22D2 MUTATED | 1 | 2 | 0 | 4 | 0 | 0
TSC22D2 WILD-TYPE | 8 | 15 | 7 | 8 | 6 | 5

'ZAR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.175 (Fisher's exact test), Q value = 1

Table S209. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
ZAR1 MUTATED | 3 | 3 | 0 | 2 | 3
ZAR1 WILD-TYPE | 18 | 16 | 8 | 6 | 3

'ZAR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S210. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
ZAR1 MUTATED | 3 | 1 | 1 | 2 | 2
ZAR1 WILD-TYPE | 10 | 7 | 13 | 12 | 5

'ZAR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.602 (Fisher's exact test), Q value = 1

Table S211. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
ZAR1 MUTATED | 3 | 0 | 2 | 4
ZAR1 WILD-TYPE | 14 | 8 | 12 | 12

'ZAR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S212. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
ZAR1 MUTATED | 3 | 2 | 0 | 4
ZAR1 WILD-TYPE | 13 | 14 | 5 | 14

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S213. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
ZAR1 MUTATED | 4 | 1 | 4
ZAR1 WILD-TYPE | 22 | 11 | 14

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S214. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
ZAR1 MUTATED | 2 | 4 | 1 | 2 | 0
ZAR1 WILD-TYPE | 11 | 15 | 7 | 12 | 2

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.52 (Fisher's exact test), Q value = 1

Table S215. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
ZAR1 MUTATED | 4 | 1 | 4
ZAR1 WILD-TYPE | 23 | 12 | 12

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S216. Gene #27: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
ZAR1 MUTATED | 2 | 4 | 0 | 2 | 0 | 1
ZAR1 WILD-TYPE | 7 | 13 | 7 | 10 | 6 | 4

'RGS9BP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.295 (Fisher's exact test), Q value = 1

Table S217. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
RGS9BP MUTATED | 1 | 3 | 2 | 2 | 0
RGS9BP WILD-TYPE | 20 | 16 | 6 | 6 | 6

'RGS9BP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.585 (Fisher's exact test), Q value = 1

Table S218. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
RGS9BP MUTATED | 3 | 0 | 3 | 1 | 1
RGS9BP WILD-TYPE | 10 | 8 | 11 | 13 | 6

'RGS9BP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S219. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
RGS9BP MUTATED | 2 | 1 | 2 | 2
RGS9BP WILD-TYPE | 15 | 7 | 12 | 14

'RGS9BP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S220. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
RGS9BP MUTATED | 2 | 3 | 0 | 2
RGS9BP WILD-TYPE | 14 | 13 | 5 | 16

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.335 (Fisher's exact test), Q value = 1

Table S221. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
RGS9BP MUTATED | 2 | 3 | 3
RGS9BP WILD-TYPE | 24 | 9 | 15

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S222. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
RGS9BP MUTATED | 2 | 2 | 1 | 3 | 0
RGS9BP WILD-TYPE | 11 | 17 | 7 | 11 | 2

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.884 (Fisher's exact test), Q value = 1

Table S223. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
RGS9BP MUTATED | 3 | 2 | 3
RGS9BP WILD-TYPE | 24 | 11 | 13

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S224. Gene #28: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
RGS9BP MUTATED | 1 | 2 | 0 | 3 | 0 | 2
RGS9BP WILD-TYPE | 8 | 15 | 7 | 9 | 6 | 3

'OPRD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S225. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
OPRD1 MUTATED | 5 | 4 | 1 | 2 | 0
OPRD1 WILD-TYPE | 16 | 15 | 7 | 6 | 6

'OPRD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.388 (Fisher's exact test), Q value = 1

Table S226. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
OPRD1 MUTATED | 3 | 1 | 3 | 1 | 3
OPRD1 WILD-TYPE | 10 | 7 | 11 | 13 | 4

'OPRD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.797 (Fisher's exact test), Q value = 1

Table S227. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
OPRD1 MUTATED | 4 | 2 | 3 | 2
OPRD1 WILD-TYPE | 13 | 6 | 11 | 14

'OPRD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.961 (Fisher's exact test), Q value = 1

Table S228. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
OPRD1 MUTATED | 3 | 4 | 1 | 3
OPRD1 WILD-TYPE | 13 | 12 | 4 | 15

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S229. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
OPRD1 MUTATED | 5 | 4 | 2
OPRD1 WILD-TYPE | 21 | 8 | 16

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S230. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
OPRD1 MUTATED | 1 | 5 | 1 | 4 | 0
OPRD1 WILD-TYPE | 12 | 14 | 7 | 10 | 2

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.469 (Fisher's exact test), Q value = 1

Table S231. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
OPRD1 MUTATED | 5 | 4 | 2
OPRD1 WILD-TYPE | 22 | 9 | 14

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S232. Gene #29: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
OPRD1 MUTATED | 1 | 5 | 1 | 4 | 0 | 0
OPRD1 WILD-TYPE | 8 | 12 | 6 | 8 | 6 | 5

'C16ORF3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S233. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
C16ORF3 MUTATED | 2 | 2 | 0 | 1 | 1
C16ORF3 WILD-TYPE | 19 | 17 | 8 | 7 | 5

'C16ORF3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00079 (Fisher's exact test), Q value = 0.78

Table S234. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
C16ORF3 MUTATED | 0 | 4 | 0 | 0 | 1
C16ORF3 WILD-TYPE | 13 | 4 | 14 | 14 | 6

Figure S23. Get High-res Image Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'C16ORF3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S235. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
C16ORF3 MUTATED | 1 | 1 | 2 | 1
C16ORF3 WILD-TYPE | 16 | 7 | 12 | 15

'C16ORF3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.831 (Fisher's exact test), Q value = 1

Table S236. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
C16ORF3 MUTATED | 2 | 2 | 0 | 1
C16ORF3 WILD-TYPE | 14 | 14 | 5 | 17

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S237. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
C16ORF3 MUTATED | 2 | 2 | 1
C16ORF3 WILD-TYPE | 24 | 10 | 17

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S238. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
C16ORF3 MUTATED | 1 | 2 | 1 | 1 | 0
C16ORF3 WILD-TYPE | 12 | 17 | 7 | 13 | 2

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S239. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
C16ORF3 MUTATED | 2 | 2 | 1
C16ORF3 WILD-TYPE | 25 | 11 | 15

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S240. Gene #30: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
C16ORF3 MUTATED | 1 | 2 | 1 | 0 | 1 | 0
C16ORF3 WILD-TYPE | 8 | 15 | 6 | 12 | 5 | 5

'FPGS MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S241. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
FPGS MUTATED | 2 | 2 | 1 | 1 | 0
FPGS WILD-TYPE | 19 | 17 | 7 | 7 | 6

'FPGS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S242. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
FPGS MUTATED | 1 | 1 | 1 | 1 | 0
FPGS WILD-TYPE | 12 | 7 | 13 | 13 | 7

'FPGS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S243. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
FPGS MUTATED | 1 | 1 | 0 | 2
FPGS WILD-TYPE | 16 | 7 | 14 | 14

'FPGS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S244. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
FPGS MUTATED | 2 | 0 | 0 | 2
FPGS WILD-TYPE | 14 | 16 | 5 | 16

'FPGS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0905 (Fisher's exact test), Q value = 1

Table S245. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
FPGS MUTATED | 0 | 2 | 2
FPGS WILD-TYPE | 26 | 10 | 16

'FPGS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S246. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
FPGS MUTATED | 0 | 2 | 0 | 2 | 0
FPGS WILD-TYPE | 13 | 17 | 8 | 12 | 2

'FPGS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S247. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
FPGS MUTATED | 1 | 1 | 2
FPGS WILD-TYPE | 26 | 12 | 14

'FPGS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S248. Gene #31: 'FPGS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
FPGS MUTATED | 0 | 2 | 0 | 2 | 0 | 0
FPGS WILD-TYPE | 9 | 15 | 7 | 10 | 6 | 5

'PLIN5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.561 (Fisher's exact test), Q value = 1

Table S249. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
PLIN5 MUTATED | 1 | 3 | 0 | 1 | 0
PLIN5 WILD-TYPE | 20 | 16 | 8 | 7 | 6

'PLIN5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.693 (Fisher's exact test), Q value = 1

Table S250. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
PLIN5 MUTATED | 1 | 2 | 1 | 1 | 0
PLIN5 WILD-TYPE | 12 | 6 | 13 | 13 | 7

'PLIN5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S251. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
PLIN5 MUTATED | 1 | 1 | 2 | 1
PLIN5 WILD-TYPE | 16 | 7 | 12 | 15

'PLIN5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S252. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
PLIN5 MUTATED | 1 | 3 | 0 | 1
PLIN5 WILD-TYPE | 15 | 13 | 5 | 17

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S253. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
PLIN5 MUTATED | 1 | 2 | 2
PLIN5 WILD-TYPE | 25 | 10 | 16

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.308 (Fisher's exact test), Q value = 1

Table S254. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
PLIN5 MUTATED | 1 | 4 | 0 | 0 | 0
PLIN5 WILD-TYPE | 12 | 15 | 8 | 14 | 2

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 1

Table S255. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
PLIN5 MUTATED | 1 | 3 | 1
PLIN5 WILD-TYPE | 26 | 10 | 15

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.321 (Fisher's exact test), Q value = 1

Table S256. Gene #32: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
PLIN5 MUTATED | 1 | 4 | 0 | 0 | 0 | 0
PLIN5 WILD-TYPE | 8 | 13 | 7 | 12 | 6 | 5

'IRX3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.333 (Fisher's exact test), Q value = 1

Table S257. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
IRX3 MUTATED | 3 | 0 | 1 | 1 | 0
IRX3 WILD-TYPE | 18 | 19 | 7 | 7 | 6

'IRX3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S258. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
IRX3 MUTATED | 0 | 1 | 2 | 1 | 0
IRX3 WILD-TYPE | 13 | 7 | 12 | 13 | 7

'IRX3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.52 (Fisher's exact test), Q value = 1

Table S259. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
IRX3 MUTATED | 2 | 1 | 1 | 0
IRX3 WILD-TYPE | 15 | 7 | 13 | 16

'IRX3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.193 (Fisher's exact test), Q value = 1

Table S260. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
IRX3 MUTATED | 1 | 2 | 1 | 0
IRX3 WILD-TYPE | 15 | 14 | 4 | 18

'IRX3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.246 (Fisher's exact test), Q value = 1

Table S261. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
IRX3 MUTATED | 2 | 2 | 0
IRX3 WILD-TYPE | 24 | 10 | 18

'IRX3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S262. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
IRX3 MUTATED | 2 | 1 | 0 | 1 | 0
IRX3 WILD-TYPE | 11 | 18 | 8 | 13 | 2

'IRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.25 (Fisher's exact test), Q value = 1

Table S263. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
IRX3 MUTATED | 2 | 2 | 0
IRX3 WILD-TYPE | 25 | 11 | 16

'IRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0204 (Fisher's exact test), Q value = 1

Table S264. Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
IRX3 MUTATED | 2 | 0 | 0 | 0 | 2 | 0
IRX3 WILD-TYPE | 7 | 17 | 7 | 12 | 4 | 5

Figure S24. Get High-res Image Gene #33: 'IRX3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'TRIOBP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.821 (Fisher's exact test), Q value = 1

Table S265. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
TRIOBP MUTATED | 5 | 4 | 2 | 1 | 0
TRIOBP WILD-TYPE | 16 | 15 | 6 | 7 | 6

'TRIOBP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 1

Table S266. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
TRIOBP MUTATED | 3 | 1 | 0 | 4 | 2
TRIOBP WILD-TYPE | 10 | 7 | 14 | 10 | 5

'TRIOBP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S267. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
TRIOBP MUTATED | 3 | 1 | 2 | 3
TRIOBP WILD-TYPE | 14 | 7 | 12 | 13

'TRIOBP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S268. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
TRIOBP MUTATED | 3 | 0 | 1 | 5
TRIOBP WILD-TYPE | 13 | 16 | 4 | 13

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.902 (Fisher's exact test), Q value = 1

Table S269. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
TRIOBP MUTATED | 4 | 2 | 4
TRIOBP WILD-TYPE | 22 | 10 | 14

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.93 (Fisher's exact test), Q value = 1

Table S270. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
TRIOBP MUTATED | 2 | 3 | 2 | 3 | 0
TRIOBP WILD-TYPE | 11 | 16 | 6 | 11 | 2

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S271. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
TRIOBP MUTATED | 4 | 2 | 4
TRIOBP WILD-TYPE | 23 | 11 | 12

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.746 (Fisher's exact test), Q value = 1

Table S272. Gene #34: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
TRIOBP MUTATED | 1 | 2 | 1 | 3 | 1 | 2
TRIOBP WILD-TYPE | 8 | 15 | 6 | 9 | 5 | 3

'KRTAP4-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S273. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
KRTAP4-5 MUTATED | 2 | 3 | 0 | 0 | 0
KRTAP4-5 WILD-TYPE | 19 | 16 | 8 | 8 | 6

'KRTAP4-5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.313 (Fisher's exact test), Q value = 1

Table S274. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
KRTAP4-5 MUTATED | 1 | 2 | 0 | 1 | 0
KRTAP4-5 WILD-TYPE | 12 | 6 | 14 | 13 | 7

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S275. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
KRTAP4-5 MUTATED | 2 | 0 | 1 | 1
KRTAP4-5 WILD-TYPE | 15 | 8 | 13 | 15

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.886 (Fisher's exact test), Q value = 1

Table S276. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
KRTAP4-5 MUTATED | 2 | 1 | 0 | 1
KRTAP4-5 WILD-TYPE | 14 | 15 | 5 | 17

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S277. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
KRTAP4-5 MUTATED | 2 | 1 | 1
KRTAP4-5 WILD-TYPE | 24 | 11 | 17

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S278. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
KRTAP4-5 MUTATED | 1 | 1 | 0 | 2 | 0
KRTAP4-5 WILD-TYPE | 12 | 18 | 8 | 12 | 2

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S279. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
KRTAP4-5 MUTATED | 2 | 1 | 1
KRTAP4-5 WILD-TYPE | 25 | 12 | 15

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S280. Gene #35: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
KRTAP4-5 MUTATED | 1 | 1 | 0 | 1 | 1 | 0
KRTAP4-5 WILD-TYPE | 8 | 16 | 7 | 11 | 5 | 5

'ATXN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.408 (Fisher's exact test), Q value = 1

Table S281. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
ATXN1 MUTATED | 3 | 3 | 3 | 0 | 1
ATXN1 WILD-TYPE | 18 | 16 | 5 | 8 | 5

'ATXN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 1

Table S282. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
ATXN1 MUTATED | 1 | 4 | 2 | 1 | 1
ATXN1 WILD-TYPE | 12 | 4 | 12 | 13 | 6

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 1

Table S283. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
ATXN1 MUTATED | 2 | 3 | 3 | 1
ATXN1 WILD-TYPE | 15 | 5 | 11 | 15

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.627 (Fisher's exact test), Q value = 1

Table S284. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
ATXN1 MUTATED | 3 | 4 | 0 | 2
ATXN1 WILD-TYPE | 13 | 12 | 5 | 16

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 1

Table S285. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
ATXN1 MUTATED | 5 | 3 | 1
ATXN1 WILD-TYPE | 21 | 9 | 17

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S286. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
ATXN1 MUTATED | 2 | 2 | 2 | 3 | 0
ATXN1 WILD-TYPE | 11 | 17 | 6 | 11 | 2

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.41 (Fisher's exact test), Q value = 1

Table S287. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
ATXN1 MUTATED | 5 | 3 | 1
ATXN1 WILD-TYPE | 22 | 10 | 15

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S288. Gene #36: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
ATXN1 MUTATED | 2 | 2 | 2 | 2 | 1 | 0
ATXN1 WILD-TYPE | 7 | 15 | 5 | 10 | 5 | 5

'ZNF628 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 1

Table S289. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
ZNF628 MUTATED | 4 | 1 | 0 | 2 | 0
ZNF628 WILD-TYPE | 17 | 18 | 8 | 6 | 6

'ZNF628 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.892 (Fisher's exact test), Q value = 1

Table S290. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
ZNF628 MUTATED | 2 | 1 | 1 | 1 | 0
ZNF628 WILD-TYPE | 11 | 7 | 13 | 13 | 7

'ZNF628 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S291. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
ZNF628 MUTATED | 3 | 1 | 1 | 0
ZNF628 WILD-TYPE | 14 | 7 | 13 | 16

'ZNF628 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.122 (Fisher's exact test), Q value = 1

Table S292. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
ZNF628 MUTATED | 3 | 1 | 1 | 0
ZNF628 WILD-TYPE | 13 | 15 | 4 | 18

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S293. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
ZNF628 MUTATED | 1 | 3 | 1
ZNF628 WILD-TYPE | 25 | 9 | 17

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.494 (Fisher's exact test), Q value = 1

Table S294. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
ZNF628 MUTATED | 0 | 3 | 0 | 2 | 0
ZNF628 WILD-TYPE | 13 | 16 | 8 | 12 | 2

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0953 (Fisher's exact test), Q value = 1

Table S295. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
ZNF628 MUTATED | 2 | 3 | 0
ZNF628 WILD-TYPE | 25 | 10 | 16

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.725 (Fisher's exact test), Q value = 1

Table S296. Gene #37: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
ZNF628 MUTATED | 0 | 2 | 0 | 2 | 1 | 0
ZNF628 WILD-TYPE | 9 | 15 | 7 | 10 | 5 | 5

'WDR34 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.674 (Fisher's exact test), Q value = 1

Table S297. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
WDR34 MUTATED | 2 | 1 | 0 | 1 | 1
WDR34 WILD-TYPE | 19 | 18 | 8 | 7 | 5

'WDR34 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S298. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
WDR34 MUTATED | 2 | 0 | 1 | 1 | 1
WDR34 WILD-TYPE | 11 | 8 | 13 | 13 | 6

'WDR34 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.931 (Fisher's exact test), Q value = 1

Table S299. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
WDR34 MUTATED | 2 | 0 | 1 | 2
WDR34 WILD-TYPE | 15 | 8 | 13 | 14

'WDR34 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S300. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
WDR34 MUTATED | 2 | 2 | 0 | 1
WDR34 WILD-TYPE | 14 | 14 | 5 | 17

'WDR34 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S301. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
WDR34 MUTATED | 3 | 1 | 1
WDR34 WILD-TYPE | 23 | 11 | 17

'WDR34 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S302. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
WDR34 MUTATED | 1 | 1 | 0 | 3 | 0
WDR34 WILD-TYPE | 12 | 18 | 8 | 11 | 2

'WDR34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S303. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
WDR34 MUTATED | 3 | 1 | 1
WDR34 WILD-TYPE | 24 | 12 | 15

'WDR34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S304. Gene #38: 'WDR34 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
WDR34 MUTATED | 0 | 1 | 1 | 3 | 0 | 0
WDR34 WILD-TYPE | 9 | 16 | 6 | 9 | 6 | 5

'BTBD11 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S305. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
BTBD11 MUTATED | 2 | 2 | 1 | 1 | 0
BTBD11 WILD-TYPE | 19 | 17 | 7 | 7 | 6

'BTBD11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.235 (Fisher's exact test), Q value = 1

Table S306. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
BTBD11 MUTATED | 1 | 1 | 1 | 0 | 2
BTBD11 WILD-TYPE | 12 | 7 | 13 | 14 | 5

'BTBD11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.48 (Fisher's exact test), Q value = 1

Table S307. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
BTBD11 MUTATED | 1 | 0 | 3 | 1
BTBD11 WILD-TYPE | 16 | 8 | 11 | 15

'BTBD11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S308. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
BTBD11 MUTATED | 1 | 2 | 0 | 2
BTBD11 WILD-TYPE | 15 | 14 | 5 | 16

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.493 (Fisher's exact test), Q value = 1

Table S309. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
BTBD11 MUTATED | 4 | 0 | 1
BTBD11 WILD-TYPE | 22 | 12 | 17

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.165 (Fisher's exact test), Q value = 1

Table S310. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
BTBD11 MUTATED | 2 | 0 | 2 | 1 | 0
BTBD11 WILD-TYPE | 11 | 19 | 6 | 13 | 2

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S311. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
BTBD11 MUTATED | 4 | 0 | 1
BTBD11 WILD-TYPE | 23 | 13 | 15

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.213 (Fisher's exact test), Q value = 1

Table S312. Gene #39: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
BTBD11 MUTATED | 2 | 0 | 1 | 1 | 0 | 1
BTBD11 WILD-TYPE | 7 | 17 | 6 | 11 | 6 | 4

'GARS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 1

Table S313. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
GARS MUTATED | 6 | 4 | 3 | 4 | 4
GARS WILD-TYPE | 15 | 15 | 5 | 4 | 2

'GARS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0685 (Fisher's exact test), Q value = 1

Table S314. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
GARS MUTATED | 2 | 0 | 4 | 6 | 4
GARS WILD-TYPE | 11 | 8 | 10 | 8 | 3

'GARS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.433 (Fisher's exact test), Q value = 1

Table S315. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
GARS MUTATED | 4 | 1 | 4 | 7
GARS WILD-TYPE | 13 | 7 | 10 | 9

'GARS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.063 (Fisher's exact test), Q value = 1

Table S316. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
GARS MUTATED | 2 | 3 | 3 | 8
GARS WILD-TYPE | 14 | 13 | 2 | 10

'GARS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.238 (Fisher's exact test), Q value = 1

Table S317. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
GARS MUTATED | 6 | 2 | 8
GARS WILD-TYPE | 20 | 10 | 10

'GARS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S318. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
GARS MUTATED | 3 | 7 | 4 | 2 | 0
GARS WILD-TYPE | 10 | 12 | 4 | 12 | 2

'GARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0989 (Fisher's exact test), Q value = 1

Table S319. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
GARS MUTATED | 6 | 2 | 8
GARS WILD-TYPE | 21 | 11 | 8

'GARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S320. Gene #40: 'GARS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
GARS MUTATED | 2 | 6 | 2 | 1 | 2 | 3
GARS WILD-TYPE | 7 | 11 | 5 | 11 | 4 | 2

'ZNF598 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S321. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
ZNF598 MUTATED | 6 | 2 | 1 | 3 | 1
ZNF598 WILD-TYPE | 15 | 17 | 7 | 5 | 5

'ZNF598 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S322. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
ZNF598 MUTATED | 3 | 0 | 2 | 4 | 0
ZNF598 WILD-TYPE | 10 | 8 | 12 | 10 | 7

'ZNF598 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.534 (Fisher's exact test), Q value = 1

Table S323. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
ZNF598 MUTATED | 4 | 0 | 3 | 2
ZNF598 WILD-TYPE | 13 | 8 | 11 | 14

'ZNF598 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S324. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
ZNF598 MUTATED | 3 | 2 | 1 | 3
ZNF598 WILD-TYPE | 13 | 14 | 4 | 15

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S325. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
ZNF598 MUTATED | 4 | 2 | 3
ZNF598 WILD-TYPE | 22 | 10 | 15

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.215 (Fisher's exact test), Q value = 1

Table S326. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
ZNF598 MUTATED | 1 | 3 | 0 | 5 | 0
ZNF598 WILD-TYPE | 12 | 16 | 8 | 9 | 2

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S327. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
ZNF598 MUTATED | 4 | 2 | 3
ZNF598 WILD-TYPE | 23 | 11 | 13

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.162 (Fisher's exact test), Q value = 1

Table S328. Gene #41: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
ZNF598 MUTATED | 1 | 3 | 0 | 5 | 0 | 0
ZNF598 WILD-TYPE | 8 | 14 | 7 | 7 | 6 | 5

'BHLHE22 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.391 (Fisher's exact test), Q value = 1

Table S329. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
BHLHE22 MUTATED | 1 | 2 | 2 | 0 | 0
BHLHE22 WILD-TYPE | 20 | 17 | 6 | 8 | 6

'BHLHE22 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0641 (Fisher's exact test), Q value = 1

Table S330. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
BHLHE22 MUTATED | 0 | 3 | 1 | 1 | 0
BHLHE22 WILD-TYPE | 13 | 5 | 13 | 13 | 7

'BHLHE22 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 1

Table S331. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
BHLHE22 MUTATED | 0 | 2 | 2 | 1
BHLHE22 WILD-TYPE | 17 | 6 | 12 | 15

'BHLHE22 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.83 (Fisher's exact test), Q value = 1

Table S332. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
BHLHE22 MUTATED | 2 | 2 | 0 | 1
BHLHE22 WILD-TYPE | 14 | 14 | 5 | 17

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.595 (Fisher's exact test), Q value = 1

Table S333. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
BHLHE22 MUTATED | 2 | 2 | 1
BHLHE22 WILD-TYPE | 24 | 10 | 17

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S334. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
BHLHE22 MUTATED | 2 | 2 | 0 | 1 | 0
BHLHE22 WILD-TYPE | 11 | 17 | 8 | 13 | 2

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S335. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
BHLHE22 MUTATED | 2 | 2 | 1
BHLHE22 WILD-TYPE | 25 | 11 | 15

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S336. Gene #42: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
BHLHE22 MUTATED | 2 | 2 | 0 | 1 | 0 | 0
BHLHE22 WILD-TYPE | 7 | 15 | 7 | 11 | 6 | 5

'PTPLA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S337. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
PTPLA MUTATED | 2 | 0 | 1 | 1 | 0
PTPLA WILD-TYPE | 19 | 19 | 7 | 7 | 6

'PTPLA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.292 (Fisher's exact test), Q value = 1

Table S338. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
PTPLA MUTATED | 0 | 1 | 2 | 0 | 0
PTPLA WILD-TYPE | 13 | 7 | 12 | 14 | 7

'PTPLA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.332 (Fisher's exact test), Q value = 1

Table S339. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
PTPLA MUTATED | 1 | 0 | 2 | 0
PTPLA WILD-TYPE | 16 | 8 | 12 | 16

'PTPLA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S340. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
PTPLA MUTATED | 1 | 2 | 0 | 0
PTPLA WILD-TYPE | 15 | 14 | 5 | 18

'PTPLA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S341. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
PTPLA MUTATED | 1 | 1 | 1
PTPLA WILD-TYPE | 25 | 11 | 17

'PTPLA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S342. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
PTPLA MUTATED | 1 | 1 | 0 | 1 | 0
PTPLA WILD-TYPE | 12 | 18 | 8 | 13 | 2

'PTPLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S343. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
PTPLA MUTATED | 1 | 2 | 0
PTPLA WILD-TYPE | 26 | 11 | 16

'PTPLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.583 (Fisher's exact test), Q value = 1

Table S344. Gene #43: 'PTPLA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
PTPLA MUTATED | 1 | 1 | 0 | 0 | 1 | 0
PTPLA WILD-TYPE | 8 | 16 | 7 | 12 | 5 | 5

'CD320 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S345. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
CD320 MUTATED | 2 | 1 | 1 | 0 | 0
CD320 WILD-TYPE | 19 | 18 | 7 | 8 | 6

'CD320 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.897 (Fisher's exact test), Q value = 1

Table S346. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
CD320 MUTATED | 1 | 0 | 1 | 2 | 0
CD320 WILD-TYPE | 12 | 8 | 13 | 12 | 7

'CD320 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.737 (Fisher's exact test), Q value = 1

Table S347. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
CD320 MUTATED | 1 | 0 | 2 | 1
CD320 WILD-TYPE | 16 | 8 | 12 | 15

'CD320 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S348. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
CD320 MUTATED | 1 | 1 | 1 | 1
CD320 WILD-TYPE | 15 | 15 | 4 | 17

'CD320 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.416 (Fisher's exact test), Q value = 1

Table S349. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
CD320 MUTATED | 3 | 1 | 0
CD320 WILD-TYPE | 23 | 11 | 18

'CD320 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.221 (Fisher's exact test), Q value = 1

Table S350. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
CD320 MUTATED | 1 | 0 | 2 | 1 | 0
CD320 WILD-TYPE | 12 | 19 | 6 | 13 | 2

'CD320 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.175 (Fisher's exact test), Q value = 1

Table S351. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
CD320 MUTATED | 4 | 0 | 0
CD320 WILD-TYPE | 23 | 13 | 16

'CD320 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S352. Gene #44: 'CD320 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
CD320 MUTATED | 1 | 0 | 2 | 1 | 0 | 0
CD320 WILD-TYPE | 8 | 17 | 5 | 11 | 6 | 5

'KIAA1984 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.252 (Fisher's exact test), Q value = 1

Table S353. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
KIAA1984 MUTATED | 1 | 0 | 1 | 1 | 1
KIAA1984 WILD-TYPE | 20 | 19 | 7 | 7 | 5

'KIAA1984 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.735 (Fisher's exact test), Q value = 1

Table S354. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
KIAA1984 MUTATED | 0 | 1 | 2 | 1 | 0
KIAA1984 WILD-TYPE | 13 | 7 | 12 | 13 | 7

'KIAA1984 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 1

Table S355. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
KIAA1984 MUTATED | 1 | 0 | 3 | 0
KIAA1984 WILD-TYPE | 16 | 8 | 11 | 16

'KIAA1984 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0463 (Fisher's exact test), Q value = 1

Table S356. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
KIAA1984 MUTATED | 0 | 3 | 1 | 0
KIAA1984 WILD-TYPE | 16 | 13 | 4 | 18

Figure S25. Get High-res Image Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0364 (Fisher's exact test), Q value = 1

Table S357. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
KIAA1984 MUTATED | 1 | 3 | 0
KIAA1984 WILD-TYPE | 25 | 9 | 18

Figure S26. Get High-res Image Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S358. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
KIAA1984 MUTATED | 0 | 1 | 1 | 2 | 0
KIAA1984 WILD-TYPE | 13 | 18 | 7 | 12 | 2

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0617 (Fisher's exact test), Q value = 1

Table S359. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
KIAA1984 MUTATED | 1 | 3 | 0
KIAA1984 WILD-TYPE | 26 | 10 | 16

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.669 (Fisher's exact test), Q value = 1

Table S360. Gene #45: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
KIAA1984 MUTATED | 0 | 1 | 1 | 2 | 0 | 0
KIAA1984 WILD-TYPE | 9 | 16 | 6 | 10 | 6 | 5

'TPO MUTATION STATUS' versus 'CN_CNMF'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S361. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
TPO MUTATED | 6 | 2 | 1 | 1 | 2
TPO WILD-TYPE | 15 | 17 | 7 | 7 | 4

'TPO MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 1

Table S362. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
TPO MUTATED | 3 | 3 | 1 | 2 | 0
TPO WILD-TYPE | 10 | 5 | 13 | 12 | 7

'TPO MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.214 (Fisher's exact test), Q value = 1

Table S363. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
TPO MUTATED | 5 | 2 | 1 | 1
TPO WILD-TYPE | 12 | 6 | 13 | 15

'TPO MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.159 (Fisher's exact test), Q value = 1

Table S364. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
TPO MUTATED | 4 | 2 | 2 | 1
TPO WILD-TYPE | 12 | 14 | 3 | 17

'TPO MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.14 (Fisher's exact test), Q value = 1

Table S365. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
TPO MUTATED | 4 | 4 | 1
TPO WILD-TYPE | 22 | 8 | 17

'TPO MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.319 (Fisher's exact test), Q value = 1

Table S366. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
TPO MUTATED | 1 | 2 | 1 | 5 | 0
TPO WILD-TYPE | 12 | 17 | 7 | 9 | 2

'TPO MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.28 (Fisher's exact test), Q value = 1

Table S367. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
TPO MUTATED | 4 | 4 | 1
TPO WILD-TYPE | 23 | 9 | 15

'TPO MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.122 (Fisher's exact test), Q value = 1

Table S368. Gene #46: 'TPO MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
TPO MUTATED | 1 | 1 | 0 | 5 | 1 | 1
TPO WILD-TYPE | 8 | 16 | 7 | 7 | 5 | 4

'AATK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 1

Table S369. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
AATK MUTATED | 0 | 4 | 1 | 0 | 1
AATK WILD-TYPE | 21 | 15 | 7 | 8 | 5

'AATK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S370. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
AATK MUTATED | 0 | 1 | 2 | 0 | 1
AATK WILD-TYPE | 13 | 7 | 12 | 14 | 6

'AATK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 1

Table S371. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
AATK MUTATED | 0 | 1 | 2 | 1
AATK WILD-TYPE | 17 | 7 | 12 | 15

'AATK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.251 (Fisher's exact test), Q value = 1

Table S372. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
AATK MUTATED | 0 | 3 | 0 | 1
AATK WILD-TYPE | 16 | 13 | 5 | 17

'AATK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S373. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
AATK MUTATED | 2 | 1 | 1
AATK WILD-TYPE | 24 | 11 | 17

'AATK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.506 (Fisher's exact test), Q value = 1

Table S374. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
AATK MUTATED | 2 | 2 | 0 | 0 | 0
AATK WILD-TYPE | 11 | 17 | 8 | 14 | 2

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S375. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
AATK MUTATED | 2 | 1 | 1
AATK WILD-TYPE | 25 | 12 | 15

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S376. Gene #47: 'AATK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
AATK MUTATED | 2 | 2 | 0 | 0 | 0 | 0
AATK WILD-TYPE | 7 | 15 | 7 | 12 | 6 | 5

'PANK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.735 (Fisher's exact test), Q value = 1

Table S377. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
PANK2 MUTATED | 3 | 1 | 0 | 1 | 0
PANK2 WILD-TYPE | 18 | 18 | 8 | 7 | 6

'PANK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S378. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
PANK2 MUTATED | 2 | 0 | 0 | 1 | 0
PANK2 WILD-TYPE | 11 | 8 | 14 | 13 | 7

'PANK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S379. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
PANK2 MUTATED | 3 | 0 | 0 | 0
PANK2 WILD-TYPE | 14 | 8 | 14 | 16

'PANK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.108 (Fisher's exact test), Q value = 1

Table S380. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
PANK2 MUTATED | 2 | 0 | 1 | 0
PANK2 WILD-TYPE | 14 | 16 | 4 | 18

'PANK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S381. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
PANK2 MUTATED | 2 | 1 | 0
PANK2 WILD-TYPE | 24 | 11 | 18

'PANK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S382. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
PANK2 MUTATED | 1 | 0 | 0 | 2 | 0
PANK2 WILD-TYPE | 12 | 19 | 8 | 12 | 2

'PANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S383. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
PANK2 MUTATED | 2 | 1 | 0
PANK2 WILD-TYPE | 25 | 12 | 16

'PANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.323 (Fisher's exact test), Q value = 1

Table S384. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
PANK2 MUTATED | 1 | 0 | 0 | 2 | 0 | 0
PANK2 WILD-TYPE | 8 | 17 | 7 | 10 | 6 | 5

'SNED1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S385. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
SNED1 MUTATED | 4 | 1 | 0 | 0 | 1
SNED1 WILD-TYPE | 17 | 18 | 8 | 8 | 5

'SNED1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S386. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
SNED1 MUTATED | 2 | 2 | 1 | 1 | 0
SNED1 WILD-TYPE | 11 | 6 | 13 | 13 | 7

'SNED1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.212 (Fisher's exact test), Q value = 1

Table S387. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
SNED1 MUTATED | 4 | 1 | 0 | 1
SNED1 WILD-TYPE | 13 | 7 | 14 | 15

'SNED1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S388. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
SNED1 MUTATED | 3 | 1 | 1 | 1
SNED1 WILD-TYPE | 13 | 15 | 4 | 17

'SNED1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0442 (Fisher's exact test), Q value = 1

Table S389. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
SNED1 MUTATED | 1 | 4 | 1
SNED1 WILD-TYPE | 25 | 8 | 17

Figure S27. Get High-res Image Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'SNED1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.649 (Fisher's exact test), Q value = 1

Table S390. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
SNED1 MUTATED | 0 | 3 | 1 | 2 | 0
SNED1 WILD-TYPE | 13 | 16 | 7 | 12 | 2

'SNED1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0459 (Fisher's exact test), Q value = 1

Table S391. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
SNED1 MUTATED | 1 | 4 | 1
SNED1 WILD-TYPE | 26 | 9 | 15

Figure S28. Get High-res Image Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'SNED1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.321 (Fisher's exact test), Q value = 1

Table S392. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
SNED1 MUTATED | 0 | 2 | 0 | 1 | 2 | 1
SNED1 WILD-TYPE | 9 | 15 | 7 | 11 | 4 | 4

'CCDC150 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S393. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
CCDC150 MUTATED | 2 | 0 | 1 | 1 | 0
CCDC150 WILD-TYPE | 19 | 19 | 7 | 7 | 6

'CCDC150 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.808 (Fisher's exact test), Q value = 1

Table S394. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
CCDC150 MUTATED | 2 | 0 | 1 | 1 | 0
CCDC150 WILD-TYPE | 11 | 8 | 13 | 13 | 7

'CCDC150 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.265 (Fisher's exact test), Q value = 1

Table S395. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
CCDC150 MUTATED | 3 | 0 | 1 | 0
CCDC150 WILD-TYPE | 14 | 8 | 13 | 16

'CCDC150 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.197 (Fisher's exact test), Q value = 1

Table S396. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
CCDC150 MUTATED | 2 | 1 | 1 | 0
CCDC150 WILD-TYPE | 14 | 15 | 4 | 18

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S397. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
CCDC150 MUTATED | 3 | 1 | 0
CCDC150 WILD-TYPE | 23 | 11 | 18

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S398. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
CCDC150 MUTATED | 1 | 0 | 0 | 3 | 0
CCDC150 WILD-TYPE | 12 | 19 | 8 | 11 | 2

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S399. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
CCDC150 MUTATED | 3 | 1 | 0
CCDC150 WILD-TYPE | 24 | 12 | 16

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.143 (Fisher's exact test), Q value = 1

Table S400. Gene #50: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
CCDC150 MUTATED | 1 | 0 | 0 | 3 | 0 | 0
CCDC150 WILD-TYPE | 8 | 17 | 7 | 9 | 6 | 5

'ERCC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.756 (Fisher's exact test), Q value = 1

Table S401. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
ERCC2 MUTATED | 3 | 3 | 2 | 2 | 0
ERCC2 WILD-TYPE | 18 | 16 | 6 | 6 | 6

'ERCC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.196 (Fisher's exact test), Q value = 1

Table S402. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
ERCC2 MUTATED | 4 | 3 | 2 | 1 | 0
ERCC2 WILD-TYPE | 9 | 5 | 12 | 13 | 7

'ERCC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S403. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
ERCC2 MUTATED | 4 | 2 | 3 | 1
ERCC2 WILD-TYPE | 13 | 6 | 11 | 15

'ERCC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.149 (Fisher's exact test), Q value = 1

Table S404. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
ERCC2 MUTATED | 5 | 4 | 0 | 1
ERCC2 WILD-TYPE | 11 | 12 | 5 | 17

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S405. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
ERCC2 MUTATED | 6 | 2 | 2
ERCC2 WILD-TYPE | 20 | 10 | 16

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.239 (Fisher's exact test), Q value = 1

Table S406. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
ERCC2 MUTATED | 3 | 2 | 0 | 5 | 0
ERCC2 WILD-TYPE | 10 | 17 | 8 | 9 | 2

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.29 (Fisher's exact test), Q value = 1

Table S407. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
ERCC2 MUTATED | 7 | 2 | 1
ERCC2 WILD-TYPE | 20 | 11 | 15

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0884 (Fisher's exact test), Q value = 1

Table S408. Gene #51: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
ERCC2 MUTATED | 3 | 2 | 0 | 5 | 0 | 0
ERCC2 WILD-TYPE | 6 | 15 | 7 | 7 | 6 | 5

'RREB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.736 (Fisher's exact test), Q value = 1

Table S409. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
RREB1 MUTATED | 3 | 1 | 1 | 0 | 0
RREB1 WILD-TYPE | 18 | 18 | 7 | 8 | 6

'RREB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.807 (Fisher's exact test), Q value = 1

Table S410. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
RREB1 MUTATED | 2 | 0 | 1 | 1 | 0
RREB1 WILD-TYPE | 11 | 8 | 13 | 13 | 7

'RREB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S411. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
RREB1 MUTATED | 1 | 1 | 1 | 0
RREB1 WILD-TYPE | 16 | 7 | 13 | 16

'RREB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S412. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
RREB1 MUTATED | 1 | 1 | 0 | 1
RREB1 WILD-TYPE | 15 | 15 | 5 | 17

'RREB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S413. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
RREB1 MUTATED | 1 | 1 | 2
RREB1 WILD-TYPE | 25 | 11 | 16

'RREB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.504 (Fisher's exact test), Q value = 1

Table S414. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
RREB1 MUTATED | 2 | 2 | 0 | 0 | 0
RREB1 WILD-TYPE | 11 | 17 | 8 | 14 | 2

'RREB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S415. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
RREB1 MUTATED | 1 | 1 | 2
RREB1 WILD-TYPE | 26 | 12 | 14

'RREB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S416. Gene #52: 'RREB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
RREB1 MUTATED | 1 | 2 | 0 | 0 | 0 | 1
RREB1 WILD-TYPE | 8 | 15 | 7 | 12 | 6 | 4

'RNF39 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.427 (Fisher's exact test), Q value = 1

Table S417. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
RNF39 MUTATED | 2 | 1 | 0 | 2 | 0
RNF39 WILD-TYPE | 19 | 18 | 8 | 6 | 6

'RNF39 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 1

Table S418. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
RNF39 MUTATED | 1 | 2 | 2 | 0 | 0
RNF39 WILD-TYPE | 12 | 6 | 12 | 14 | 7

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 1

Table S419. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
RNF39 MUTATED | 1 | 1 | 3 | 0
RNF39 WILD-TYPE | 16 | 7 | 11 | 16

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.267 (Fisher's exact test), Q value = 1

Table S420. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
RNF39 MUTATED | 2 | 3 | 0 | 0
RNF39 WILD-TYPE | 14 | 13 | 5 | 18

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 1

Table S421. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
RNF39 MUTATED | 3 | 2 | 0
RNF39 WILD-TYPE | 23 | 10 | 18

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S422. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
RNF39 MUTATED | 2 | 1 | 0 | 2 | 0
RNF39 WILD-TYPE | 11 | 18 | 8 | 12 | 2

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S423. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
RNF39 MUTATED | 3 | 2 | 0
RNF39 WILD-TYPE | 24 | 11 | 16

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S424. Gene #53: 'RNF39 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
RNF39 MUTATED | 2 | 1 | 0 | 2 | 0 | 0
RNF39 WILD-TYPE | 7 | 16 | 7 | 10 | 6 | 5

'SEMA5B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S425. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
SEMA5B MUTATED | 5 | 2 | 0 | 0 | 1
SEMA5B WILD-TYPE | 16 | 17 | 8 | 8 | 5

'SEMA5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S426. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
SEMA5B MUTATED | 2 | 1 | 0 | 3 | 0
SEMA5B WILD-TYPE | 11 | 7 | 14 | 11 | 7

'SEMA5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S427. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
SEMA5B MUTATED | 3 | 1 | 0 | 2
SEMA5B WILD-TYPE | 14 | 7 | 14 | 14

'SEMA5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.274 (Fisher's exact test), Q value = 1

Table S428. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
SEMA5B MUTATED | 3 | 0 | 1 | 2
SEMA5B WILD-TYPE | 13 | 16 | 4 | 16

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S429. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
SEMA5B MUTATED | 2 | 2 | 2
SEMA5B WILD-TYPE | 24 | 10 | 16

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.337 (Fisher's exact test), Q value = 1

Table S430. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
SEMA5B MUTATED | 0 | 4 | 0 | 2 | 0
SEMA5B WILD-TYPE | 13 | 15 | 8 | 12 | 2

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.637 (Fisher's exact test), Q value = 1

Table S431. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
SEMA5B MUTATED | 2 | 2 | 2
SEMA5B WILD-TYPE | 25 | 11 | 14

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.666 (Fisher's exact test), Q value = 1

Table S432. Gene #54: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
SEMA5B MUTATED | 0 | 3 | 0 | 2 | 1 | 0
SEMA5B WILD-TYPE | 9 | 14 | 7 | 10 | 5 | 5

'TAF5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.937 (Fisher's exact test), Q value = 1

Table S433. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
TAF5 MUTATED | 2 | 1 | 1 | 0 | 0
TAF5 WILD-TYPE | 19 | 18 | 7 | 8 | 6

'TAF5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S434. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
TAF5 MUTATED | 1 | 1 | 1 | 0 | 1
TAF5 WILD-TYPE | 12 | 7 | 13 | 14 | 6

'TAF5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S435. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
TAF5 MUTATED | 1 | 1 | 1 | 1
TAF5 WILD-TYPE | 16 | 7 | 13 | 15

'TAF5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.884 (Fisher's exact test), Q value = 1

Table S436. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
TAF5 MUTATED | 2 | 1 | 0 | 1
TAF5 WILD-TYPE | 14 | 15 | 5 | 17

'TAF5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0212 (Fisher's exact test), Q value = 1

Table S437. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
TAF5 MUTATED | 0 | 3 | 1
TAF5 WILD-TYPE | 26 | 9 | 17

Figure S29. Get High-res Image Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'TAF5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.121 (Fisher's exact test), Q value = 1

Table S438. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
TAF5 MUTATED | 0 | 4 | 0 | 0 | 0
TAF5 WILD-TYPE | 13 | 15 | 8 | 14 | 2

'TAF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0195 (Fisher's exact test), Q value = 1

Table S439. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
TAF5 MUTATED | 0 | 3 | 1
TAF5 WILD-TYPE | 27 | 10 | 15

Figure S30. Get High-res Image Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'TAF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.197 (Fisher's exact test), Q value = 1

Table S440. Gene #55: 'TAF5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
TAF5 MUTATED | 0 | 4 | 0 | 0 | 0 | 0
TAF5 WILD-TYPE | 9 | 13 | 7 | 12 | 6 | 5

'SARM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0301 (Fisher's exact test), Q value = 1

Table S441. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
SARM1 MUTATED | 4 | 0 | 0 | 3 | 0
SARM1 WILD-TYPE | 17 | 19 | 8 | 5 | 6

Figure S31. Get High-res Image Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'SARM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.435 (Fisher's exact test), Q value = 1

Table S442. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
SARM1 MUTATED | 0 | 1 | 3 | 2 | 0
SARM1 WILD-TYPE | 13 | 7 | 11 | 12 | 7

'SARM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.275 (Fisher's exact test), Q value = 1

Table S443. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
SARM1 MUTATED | 2 | 1 | 3 | 0
SARM1 WILD-TYPE | 15 | 7 | 11 | 16

'SARM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0285 (Fisher's exact test), Q value = 1

Table S444. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
SARM1 MUTATED | 1 | 3 | 2 | 0
SARM1 WILD-TYPE | 15 | 13 | 3 | 18

Figure S32. Get High-res Image Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'SARM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 1

Table S445. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
SARM1 MUTATED | 1 | 3 | 2
SARM1 WILD-TYPE | 25 | 9 | 16

'SARM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.754 (Fisher's exact test), Q value = 1

Table S446. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
SARM1 MUTATED | 2 | 3 | 0 | 1 | 0
SARM1 WILD-TYPE | 11 | 16 | 8 | 13 | 2

'SARM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.046 (Fisher's exact test), Q value = 1

Table S447. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
SARM1 MUTATED | 1 | 4 | 1
SARM1 WILD-TYPE | 26 | 9 | 15

Figure S33. Get High-res Image Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'SARM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.917 (Fisher's exact test), Q value = 1

Table S448. Gene #56: 'SARM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
SARM1 MUTATED | 1 | 2 | 0 | 1 | 1 | 1
SARM1 WILD-TYPE | 8 | 15 | 7 | 11 | 5 | 4

'PRSS27 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.797 (Fisher's exact test), Q value = 1

Table S449. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
PRSS27 MUTATED | 1 | 1 | 1 | 0 | 0
PRSS27 WILD-TYPE | 20 | 18 | 7 | 8 | 6

'PRSS27 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.909 (Fisher's exact test), Q value = 1

Table S450. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
PRSS27 MUTATED | 0 | 1 | 1 | 1 | 0
PRSS27 WILD-TYPE | 13 | 7 | 13 | 13 | 7

'PRSS27 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S451. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
PRSS27 MUTATED | 1 | 1 | 1 | 0
PRSS27 WILD-TYPE | 16 | 7 | 13 | 16

'PRSS27 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.108 (Fisher's exact test), Q value = 1

Table S452. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
PRSS27 MUTATED | 0 | 2 | 1 | 0
PRSS27 WILD-TYPE | 16 | 14 | 4 | 18

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S453. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
PRSS27 MUTATED | 1 | 2 | 0
PRSS27 WILD-TYPE | 25 | 10 | 18

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S454. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
PRSS27 MUTATED | 1 | 1 | 0 | 1 | 0
PRSS27 WILD-TYPE | 12 | 18 | 8 | 13 | 2

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.206 (Fisher's exact test), Q value = 1

Table S455. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
PRSS27 MUTATED | 1 | 2 | 0
PRSS27 WILD-TYPE | 26 | 11 | 16

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S456. Gene #57: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
PRSS27 MUTATED | 1 | 1 | 0 | 1 | 0 | 0
PRSS27 WILD-TYPE | 8 | 16 | 7 | 11 | 6 | 5

'TMEM189 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.162 (Fisher's exact test), Q value = 1

Table S457. Gene #58: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
TMEM189 MUTATED | 2 | 0 | 0 | 2 | 0
TMEM189 WILD-TYPE | 19 | 19 | 8 | 6 | 6

'NOXA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 1

Table S458. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
NOXA1 MUTATED | 3 | 0 | 2 | 0 | 0
NOXA1 WILD-TYPE | 18 | 19 | 6 | 8 | 6

'NOXA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 1

Table S459. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
NOXA1 MUTATED | 2 | 0 | 1 | 0 | 0
NOXA1 WILD-TYPE | 11 | 8 | 13 | 14 | 7

'NOXA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 1

Table S460. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
NOXA1 MUTATED | 2 | 1 | 0 | 0
NOXA1 WILD-TYPE | 15 | 7 | 14 | 16

'NOXA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S461. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
NOXA1 MUTATED | 2 | 1 | 0 | 0
NOXA1 WILD-TYPE | 14 | 15 | 5 | 18

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S462. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
NOXA1 MUTATED | 3 | 0 | 0
NOXA1 WILD-TYPE | 23 | 12 | 18

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.341 (Fisher's exact test), Q value = 1

Table S463. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
NOXA1 MUTATED | 1 | 0 | 0 | 2 | 0
NOXA1 WILD-TYPE | 12 | 19 | 8 | 12 | 2

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S464. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
NOXA1 MUTATED | 3 | 0 | 0
NOXA1 WILD-TYPE | 24 | 13 | 16

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.328 (Fisher's exact test), Q value = 1

Table S465. Gene #59: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
NOXA1 MUTATED | 1 | 0 | 0 | 2 | 0 | 0
NOXA1 WILD-TYPE | 8 | 17 | 7 | 10 | 6 | 5

'LRP11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0406 (Fisher's exact test), Q value = 1

Table S466. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
LRP11 MUTATED | 0 | 2 | 1 | 3 | 0
LRP11 WILD-TYPE | 21 | 17 | 7 | 5 | 6

Figure S34. Get High-res Image Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'LRP11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0727 (Fisher's exact test), Q value = 1

Table S467. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
LRP11 MUTATED | 1 | 0 | 4 | 0 | 0
LRP11 WILD-TYPE | 12 | 8 | 10 | 14 | 7

'LRP11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S468. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
LRP11 MUTATED | 1 | 1 | 2 | 1
LRP11 WILD-TYPE | 16 | 7 | 12 | 15

'LRP11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.541 (Fisher's exact test), Q value = 1

Table S469. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
LRP11 MUTATED | 1 | 3 | 0 | 1
LRP11 WILD-TYPE | 15 | 13 | 5 | 17

'LRP11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S470. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
LRP11 MUTATED | 2 | 2 | 1
LRP11 WILD-TYPE | 24 | 10 | 17

'LRP11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S471. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
LRP11 MUTATED | 1 | 2 | 0 | 2 | 0
LRP11 WILD-TYPE | 12 | 17 | 8 | 12 | 2

'LRP11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S472. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
LRP11 MUTATED | 2 | 2 | 1
LRP11 WILD-TYPE | 25 | 11 | 15

'LRP11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.95 (Fisher's exact test), Q value = 1

Table S473. Gene #60: 'LRP11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
LRP11 MUTATED | 1 | 2 | 0 | 2 | 0 | 0
LRP11 WILD-TYPE | 8 | 15 | 7 | 10 | 6 | 5

'RNF149 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.376 (Fisher's exact test), Q value = 1

Table S474. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
RNF149 MUTATED | 0 | 2 | 1 | 1 | 0
RNF149 WILD-TYPE | 21 | 17 | 7 | 7 | 6

'RNF149 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0356 (Fisher's exact test), Q value = 1

Table S475. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
RNF149 MUTATED | 0 | 0 | 2 | 0 | 2
RNF149 WILD-TYPE | 13 | 8 | 12 | 14 | 5

Figure S35. Get High-res Image Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'RNF149 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 1

Table S476. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
RNF149 MUTATED | 0 | 1 | 2 | 1
RNF149 WILD-TYPE | 17 | 7 | 12 | 15

'RNF149 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.616 (Fisher's exact test), Q value = 1

Table S477. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
RNF149 MUTATED | 0 | 2 | 0 | 2
RNF149 WILD-TYPE | 16 | 14 | 5 | 16

'RNF149 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S478. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
RNF149 MUTATED | 1 | 2 | 1
RNF149 WILD-TYPE | 25 | 10 | 17

'RNF149 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S479. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
RNF149 MUTATED | 0 | 3 | 1 | 0 | 0
RNF149 WILD-TYPE | 13 | 16 | 7 | 14 | 2

'RNF149 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S480. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
RNF149 MUTATED | 1 | 2 | 1
RNF149 WILD-TYPE | 26 | 11 | 15

'RNF149 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S481. Gene #61: 'RNF149 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
RNF149 MUTATED | 0 | 3 | 1 | 0 | 0 | 0
RNF149 WILD-TYPE | 9 | 14 | 6 | 12 | 6 | 5

'DMKN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S482. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
DMKN MUTATED | 1 | 1 | 0 | 1 | 0
DMKN WILD-TYPE | 20 | 18 | 8 | 7 | 6

'DMKN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.292 (Fisher's exact test), Q value = 1

Table S483. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
DMKN MUTATED | 0 | 1 | 2 | 0 | 0
DMKN WILD-TYPE | 13 | 7 | 12 | 14 | 7

'DMKN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.611 (Fisher's exact test), Q value = 1

Table S484. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
DMKN MUTATED | 1 | 1 | 1 | 0
DMKN WILD-TYPE | 16 | 7 | 13 | 16

'DMKN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S485. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
DMKN MUTATED | 1 | 2 | 0 | 0
DMKN WILD-TYPE | 15 | 14 | 5 | 18

'DMKN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00831 (Fisher's exact test), Q value = 1

Table S486. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
DMKN MUTATED | 0 | 3 | 0
DMKN WILD-TYPE | 26 | 9 | 18

Figure S36. Get High-res Image Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'DMKN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.56 (Fisher's exact test), Q value = 1

Table S487. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
DMKN MUTATED | 0 | 1 | 0 | 2 | 0
DMKN WILD-TYPE | 13 | 18 | 8 | 12 | 2

'DMKN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0101 (Fisher's exact test), Q value = 1

Table S488. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
DMKN MUTATED | 0 | 3 | 0
DMKN WILD-TYPE | 27 | 10 | 16

Figure S37. Get High-res Image Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'DMKN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S489. Gene #62: 'DMKN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
DMKN MUTATED | 0 | 1 | 0 | 1 | 1 | 0
DMKN WILD-TYPE | 9 | 16 | 7 | 11 | 5 | 5

'FANK1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S490. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
FANK1 MUTATED | 2 | 1 | 1 | 0 | 0
FANK1 WILD-TYPE | 19 | 18 | 7 | 8 | 6

'FANK1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S491. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
FANK1 MUTATED | 0 | 1 | 0 | 1 | 1
FANK1 WILD-TYPE | 13 | 7 | 14 | 13 | 6

'FANK1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S492. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
FANK1 MUTATED | 1 | 1 | 0 | 1
FANK1 WILD-TYPE | 16 | 7 | 14 | 15

'FANK1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.328 (Fisher's exact test), Q value = 1

Table S493. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
FANK1 MUTATED | 1 | 0 | 1 | 1
FANK1 WILD-TYPE | 15 | 16 | 4 | 17

'FANK1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S494. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
FANK1 MUTATED | 1 | 1 | 1
FANK1 WILD-TYPE | 25 | 11 | 17

'FANK1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.227 (Fisher's exact test), Q value = 1

Table S495. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
FANK1 MUTATED | 0 | 0 | 1 | 2 | 0
FANK1 WILD-TYPE | 13 | 19 | 7 | 12 | 2

'FANK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S496. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
FANK1 MUTATED | 1 | 1 | 1
FANK1 WILD-TYPE | 26 | 12 | 15

'FANK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S497. Gene #63: 'FANK1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
FANK1 MUTATED | 0 | 0 | 0 | 1 | 1 | 1
FANK1 WILD-TYPE | 9 | 17 | 7 | 11 | 5 | 4

'MUC5B MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S498. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
MUC5B MUTATED | 7 | 6 | 3 | 3 | 2
MUC5B WILD-TYPE | 14 | 13 | 5 | 5 | 4

'MUC5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.572 (Fisher's exact test), Q value = 1

Table S499. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
MUC5B MUTATED | 3 | 3 | 6 | 4 | 4
MUC5B WILD-TYPE | 10 | 5 | 8 | 10 | 3

'MUC5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S500. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
MUC5B MUTATED | 5 | 3 | 7 | 5
MUC5B WILD-TYPE | 12 | 5 | 7 | 11

'MUC5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.731 (Fisher's exact test), Q value = 1

Table S501. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
MUC5B MUTATED | 4 | 7 | 2 | 7
MUC5B WILD-TYPE | 12 | 9 | 3 | 11

'MUC5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S502. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
MUC5B MUTATED | 8 | 5 | 7
MUC5B WILD-TYPE | 18 | 7 | 11

'MUC5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S503. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
MUC5B MUTATED | 3 | 7 | 4 | 6 | 0
MUC5B WILD-TYPE | 10 | 12 | 4 | 8 | 2

'MUC5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S504. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
MUC5B MUTATED | 8 | 6 | 6
MUC5B WILD-TYPE | 19 | 7 | 10

'MUC5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.846 (Fisher's exact test), Q value = 1

Table S505. Gene #64: 'MUC5B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
MUC5B MUTATED | 3 | 6 | 2 | 6 | 1 | 2
MUC5B WILD-TYPE | 6 | 11 | 5 | 6 | 5 | 3

'PABPC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.415 (Fisher's exact test), Q value = 1

Table S506. Gene #65: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
PABPC1 MUTATED | 1 | 1 | 2 | 0 | 0
PABPC1 WILD-TYPE | 20 | 18 | 6 | 8 | 6

'GLTPD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0714 (Fisher's exact test), Q value = 1

Table S507. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
GLTPD2 MUTATED | 1 | 1 | 0 | 3 | 1
GLTPD2 WILD-TYPE | 20 | 18 | 8 | 5 | 5

'GLTPD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S508. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
GLTPD2 MUTATED | 1 | 0 | 2 | 2 | 1
GLTPD2 WILD-TYPE | 12 | 8 | 12 | 12 | 6

'GLTPD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S509. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
GLTPD2 MUTATED | 2 | 0 | 2 | 2
GLTPD2 WILD-TYPE | 15 | 8 | 12 | 14

'GLTPD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S510. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
GLTPD2 MUTATED | 1 | 3 | 1 | 1
GLTPD2 WILD-TYPE | 15 | 13 | 4 | 17

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S511. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
GLTPD2 MUTATED | 3 | 2 | 1
GLTPD2 WILD-TYPE | 23 | 10 | 17

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S512. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
GLTPD2 MUTATED | 2 | 1 | 0 | 3 | 0
GLTPD2 WILD-TYPE | 11 | 18 | 8 | 11 | 2

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.858 (Fisher's exact test), Q value = 1

Table S513. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
GLTPD2 MUTATED | 3 | 2 | 1
GLTPD2 WILD-TYPE | 24 | 11 | 15

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S514. Gene #66: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
GLTPD2 MUTATED | 1 | 1 | 1 | 3 | 0 | 0
GLTPD2 WILD-TYPE | 8 | 16 | 6 | 9 | 6 | 5

'MEN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0955 (Fisher's exact test), Q value = 1

Table S515. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
MEN1 MUTATED | 0 | 1 | 1 | 2 | 0
MEN1 WILD-TYPE | 21 | 18 | 7 | 6 | 6

'MEN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0433 (Fisher's exact test), Q value = 1

Table S516. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
MEN1 MUTATED | 0 | 1 | 4 | 0 | 0
MEN1 WILD-TYPE | 13 | 7 | 10 | 14 | 7

Figure S38. Get High-res Image Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'MEN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0127 (Fisher's exact test), Q value = 1

Table S517. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
MEN1 MUTATED | 0 | 1 | 4 | 0
MEN1 WILD-TYPE | 17 | 7 | 10 | 16

Figure S39. Get High-res Image Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'MEN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00613 (Fisher's exact test), Q value = 1

Table S518. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
MEN1 MUTATED | 0 | 5 | 0 | 0
MEN1 WILD-TYPE | 16 | 11 | 5 | 18

Figure S40. Get High-res Image Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'MEN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 1

Table S519. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
MEN1 MUTATED | 4 | 1 | 0
MEN1 WILD-TYPE | 22 | 11 | 18

'MEN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0387 (Fisher's exact test), Q value = 1

Table S520. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
MEN1 MUTATED | 4 | 0 | 0 | 1 | 0
MEN1 WILD-TYPE | 9 | 19 | 8 | 13 | 2

Figure S41. Get High-res Image Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'MEN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S521. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
MEN1 MUTATED | 4 | 1 | 0
MEN1 WILD-TYPE | 23 | 12 | 16

'MEN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00889 (Fisher's exact test), Q value = 1

Table S522. Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
MEN1 MUTATED | 4 | 0 | 0 | 1 | 0 | 0
MEN1 WILD-TYPE | 5 | 17 | 7 | 11 | 6 | 5

Figure S42. Get High-res Image Gene #67: 'MEN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'SRPX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S523. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
SRPX MUTATED | 1 | 2 | 0 | 0 | 0
SRPX WILD-TYPE | 20 | 17 | 8 | 8 | 6

'SRPX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S524. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
SRPX MUTATED | 0 | 2 | 0 | 1 | 0
SRPX WILD-TYPE | 13 | 6 | 14 | 13 | 7

'SRPX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S525. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
SRPX MUTATED | 0 | 1 | 1 | 1
SRPX WILD-TYPE | 17 | 7 | 13 | 15

'SRPX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S526. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
SRPX MUTATED | 1 | 1 | 0 | 1
SRPX WILD-TYPE | 15 | 15 | 5 | 17

'SRPX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.789 (Fisher's exact test), Q value = 1

Table S527. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
SRPX MUTATED | 1 | 1 | 1
SRPX WILD-TYPE | 25 | 11 | 17

'SRPX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.789 (Fisher's exact test), Q value = 1

Table S528. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
SRPX MUTATED | 1 | 2 | 0 | 0 | 0
SRPX WILD-TYPE | 12 | 17 | 8 | 14 | 2

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S529. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
SRPX MUTATED | 1 | 1 | 1
SRPX WILD-TYPE | 26 | 12 | 15

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S530. Gene #68: 'SRPX MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
SRPX MUTATED | 1 | 2 | 0 | 0 | 0 | 0
SRPX WILD-TYPE | 8 | 15 | 7 | 12 | 6 | 5

'MAP1S MUTATION STATUS' versus 'CN_CNMF'

P value = 0.276 (Fisher's exact test), Q value = 1

Table S531. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
MAP1S MUTATED | 0 | 2 | 1 | 1 | 1
MAP1S WILD-TYPE | 21 | 17 | 7 | 7 | 5

'MAP1S MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S532. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
MAP1S MUTATED | 1 | 1 | 0 | 3 | 0
MAP1S WILD-TYPE | 12 | 7 | 14 | 11 | 7

'MAP1S MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S533. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
MAP1S MUTATED | 1 | 1 | 0 | 3
MAP1S WILD-TYPE | 16 | 7 | 14 | 13

'MAP1S MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S534. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
MAP1S MUTATED | 2 | 1 | 0 | 2
MAP1S WILD-TYPE | 14 | 15 | 5 | 16

'MAP1S MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S535. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
MAP1S MUTATED | 2 | 1 | 2
MAP1S WILD-TYPE | 24 | 11 | 16

'MAP1S MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S536. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
MAP1S MUTATED | 2 | 2 | 0 | 1 | 0
MAP1S WILD-TYPE | 11 | 17 | 8 | 13 | 2

'MAP1S MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S537. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
MAP1S MUTATED | 2 | 1 | 2
MAP1S WILD-TYPE | 25 | 12 | 14

'MAP1S MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S538. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
MAP1S MUTATED | 1 | 2 | 1 | 1 | 0 | 0
MAP1S WILD-TYPE | 8 | 15 | 6 | 11 | 6 | 5

'SCRT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S539. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
SCRT1 MUTATED | 1 | 1 | 0 | 1 | 0
SCRT1 WILD-TYPE | 20 | 18 | 8 | 7 | 6

'SCRT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 1

Table S540. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
SCRT1 MUTATED | 2 | 0 | 0 | 1 | 0
SCRT1 WILD-TYPE | 11 | 8 | 14 | 13 | 7

'SCRT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S541. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
SCRT1 MUTATED | 2 | 0 | 1 | 0
SCRT1 WILD-TYPE | 15 | 8 | 13 | 16

'SCRT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.639 (Fisher's exact test), Q value = 1

Table S542. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
SCRT1 MUTATED | 2 | 0 | 0 | 1
SCRT1 WILD-TYPE | 14 | 16 | 5 | 17

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S543. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
SCRT1 MUTATED | 2 | 1 | 0
SCRT1 WILD-TYPE | 24 | 11 | 18

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.71 (Fisher's exact test), Q value = 1

Table S544. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
SCRT1 MUTATED | 0 | 1 | 1 | 1 | 0
SCRT1 WILD-TYPE | 13 | 18 | 7 | 13 | 2

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.592 (Fisher's exact test), Q value = 1

Table S545. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
SCRT1 MUTATED | 2 | 1 | 0
SCRT1 WILD-TYPE | 25 | 12 | 16

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S546. Gene #70: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
SCRT1 MUTATED | 0 | 1 | 1 | 1 | 0 | 0
SCRT1 WILD-TYPE | 9 | 16 | 6 | 11 | 6 | 5

'OBSCN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.657 (Fisher's exact test), Q value = 1

Table S547. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
OBSCN MUTATED | 9 | 6 | 1 | 2 | 2
OBSCN WILD-TYPE | 12 | 13 | 7 | 6 | 4

'OBSCN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 1

Table S548. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
OBSCN MUTATED | 4 | 5 | 2 | 5 | 2
OBSCN WILD-TYPE | 9 | 3 | 12 | 9 | 5

'OBSCN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.458 (Fisher's exact test), Q value = 1

Table S549. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
OBSCN MUTATED | 7 | 2 | 6 | 3
OBSCN WILD-TYPE | 10 | 6 | 8 | 13

'OBSCN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S550. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
OBSCN MUTATED | 5 | 5 | 3 | 5
OBSCN WILD-TYPE | 11 | 11 | 2 | 13

'OBSCN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0945 (Fisher's exact test), Q value = 1

Table S551. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
OBSCN MUTATED | 7 | 7 | 4
OBSCN WILD-TYPE | 19 | 5 | 14

'OBSCN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S552. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
OBSCN MUTATED | 3 | 6 | 3 | 6 | 0
OBSCN WILD-TYPE | 10 | 13 | 5 | 8 | 2

'OBSCN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.196 (Fisher's exact test), Q value = 1

Table S553. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
OBSCN MUTATED | 7 | 7 | 4
OBSCN WILD-TYPE | 20 | 6 | 12

'OBSCN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.73 (Fisher's exact test), Q value = 1

Table S554. Gene #71: 'OBSCN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
OBSCN MUTATED | 2 | 4 | 2 | 6 | 2 | 2
OBSCN WILD-TYPE | 7 | 13 | 5 | 6 | 4 | 3

'IER5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.369 (Fisher's exact test), Q value = 1

Table S555. Gene #72: 'IER5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
IER5 MUTATED | 3 | 0 | 0 | 0 | 0
IER5 WILD-TYPE | 18 | 19 | 8 | 8 | 6

'TNIP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S556. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
TNIP2 MUTATED | 2 | 1 | 0 | 1 | 1
TNIP2 WILD-TYPE | 19 | 18 | 8 | 7 | 5

'TNIP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S557. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
TNIP2 MUTATED | 1 | 1 | 2 | 0 | 0
TNIP2 WILD-TYPE | 12 | 7 | 12 | 14 | 7

'TNIP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.735 (Fisher's exact test), Q value = 1

Table S558. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
TNIP2 MUTATED | 1 | 0 | 2 | 1
TNIP2 WILD-TYPE | 16 | 8 | 12 | 15

'TNIP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S559. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
TNIP2 MUTATED | 1 | 2 | 0 | 1
TNIP2 WILD-TYPE | 15 | 14 | 5 | 17

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S560. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
TNIP2 MUTATED | 2 | 1 | 1
TNIP2 WILD-TYPE | 24 | 11 | 17

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.402 (Fisher's exact test), Q value = 1

Table S561. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
TNIP2 MUTATED | 1 | 0 | 1 | 2 | 0
TNIP2 WILD-TYPE | 12 | 19 | 7 | 12 | 2

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S562. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
TNIP2 MUTATED | 2 | 1 | 1
TNIP2 WILD-TYPE | 25 | 12 | 15

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.235 (Fisher's exact test), Q value = 1

Table S563. Gene #73: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
TNIP2 MUTATED | 1 | 0 | 0 | 2 | 0 | 1
TNIP2 WILD-TYPE | 8 | 17 | 7 | 10 | 6 | 4

'NOTCH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.304 (Fisher's exact test), Q value = 1

Table S564. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
NOTCH2 MUTATED | 4 | 1 | 0 | 2 | 0
NOTCH2 WILD-TYPE | 17 | 18 | 8 | 6 | 6

'NOTCH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.798 (Fisher's exact test), Q value = 1

Table S565. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
NOTCH2 MUTATED | 1 | 0 | 2 | 2 | 0
NOTCH2 WILD-TYPE | 12 | 8 | 12 | 12 | 7

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S566. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
NOTCH2 MUTATED | 3 | 1 | 1 | 0
NOTCH2 WILD-TYPE | 14 | 7 | 13 | 16

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0338 (Fisher's exact test), Q value = 1

Table S567. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
NOTCH2 MUTATED | 1 | 2 | 2 | 0
NOTCH2 WILD-TYPE | 15 | 14 | 3 | 18

Figure S43. Get High-res Image Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00835 (Fisher's exact test), Q value = 1

Table S568. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
NOTCH2 MUTATED | 1 | 4 | 0
NOTCH2 WILD-TYPE | 25 | 8 | 18

Figure S44. Get High-res Image Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S569. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
NOTCH2 MUTATED | 0 | 2 | 0 | 3 | 0
NOTCH2 WILD-TYPE | 13 | 17 | 8 | 11 | 2

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00893 (Fisher's exact test), Q value = 1

Table S570. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
NOTCH2 MUTATED | 1 | 4 | 0
NOTCH2 WILD-TYPE | 26 | 9 | 16

Figure S45. Get High-res Image Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.325 (Fisher's exact test), Q value = 1

Table S571. Gene #74: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
NOTCH2 MUTATED | 0 | 1 | 0 | 3 | 1 | 0
NOTCH2 WILD-TYPE | 9 | 16 | 7 | 9 | 5 | 5

'RASIP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.63 (Fisher's exact test), Q value = 1

Table S572. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
RASIP1 MUTATED | 3 | 2 | 2 | 0 | 0
RASIP1 WILD-TYPE | 18 | 17 | 6 | 8 | 6

'RASIP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S573. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
RASIP1 MUTATED | 2 | 2 | 2 | 1 | 0
RASIP1 WILD-TYPE | 11 | 6 | 12 | 13 | 7

'RASIP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0391 (Fisher's exact test), Q value = 1

Table S574. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
RASIP1 MUTATED | 3 | 3 | 1 | 0
RASIP1 WILD-TYPE | 14 | 5 | 13 | 16

Figure S46. Get High-res Image Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'RASIP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.159 (Fisher's exact test), Q value = 1

Table S575. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
RASIP1 MUTATED | 3 | 3 | 1 | 0
RASIP1 WILD-TYPE | 13 | 13 | 4 | 18

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.022 (Fisher's exact test), Q value = 1

Table S576. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
RASIP1 MUTATED | 3 | 4 | 0
RASIP1 WILD-TYPE | 23 | 8 | 18

Figure S47. Get High-res Image Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.686 (Fisher's exact test), Q value = 1

Table S577. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
RASIP1 MUTATED | 1 | 3 | 0 | 3 | 0
RASIP1 WILD-TYPE | 12 | 16 | 8 | 11 | 2

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0377 (Fisher's exact test), Q value = 1

Table S578. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
RASIP1 MUTATED | 3 | 4 | 0
RASIP1 WILD-TYPE | 24 | 9 | 16

Figure S48. Get High-res Image Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S579. Gene #75: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
RASIP1 MUTATED | 1 | 2 | 0 | 3 | 1 | 0
RASIP1 WILD-TYPE | 8 | 15 | 7 | 9 | 5 | 5

'NMU MUTATION STATUS' versus 'CN_CNMF'

P value = 0.821 (Fisher's exact test), Q value = 1

Table S580. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
NMU MUTATED | 1 | 2 | 1 | 0 | 0
NMU WILD-TYPE | 20 | 17 | 7 | 8 | 6

'NMU MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S581. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
NMU MUTATED | 1 | 1 | 1 | 1 | 0
NMU WILD-TYPE | 12 | 7 | 13 | 13 | 7

'NMU MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0485 (Fisher's exact test), Q value = 1

Table S582. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
NMU MUTATED | 0 | 2 | 0 | 1
NMU WILD-TYPE | 17 | 6 | 14 | 15

Figure S49. Get High-res Image Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'NMU MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.639 (Fisher's exact test), Q value = 1

Table S583. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
NMU MUTATED | 0 | 2 | 0 | 1
NMU WILD-TYPE | 16 | 14 | 5 | 17

'NMU MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S584. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
NMU MUTATED | 2 | 1 | 1
NMU WILD-TYPE | 24 | 11 | 17

'NMU MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.506 (Fisher's exact test), Q value = 1

Table S585. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
NMU MUTATED | 2 | 2 | 0 | 0 | 0
NMU WILD-TYPE | 11 | 17 | 8 | 14 | 2

'NMU MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S586. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
NMU MUTATED | 2 | 1 | 1
NMU WILD-TYPE | 25 | 12 | 15

'NMU MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S587. Gene #76: 'NMU MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
NMU MUTATED | 2 | 2 | 0 | 0 | 0 | 0
NMU WILD-TYPE | 7 | 15 | 7 | 12 | 6 | 5

'VARS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S588. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
VARS MUTATED | 1 | 2 | 1 | 2 | 0
VARS WILD-TYPE | 20 | 17 | 7 | 6 | 6

'VARS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.437 (Fisher's exact test), Q value = 1

Table S589. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
VARS MUTATED | 0 | 1 | 3 | 2 | 0
VARS WILD-TYPE | 13 | 7 | 11 | 12 | 7

'VARS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 1

Table S590. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
VARS MUTATED | 1 | 0 | 4 | 1
VARS WILD-TYPE | 16 | 8 | 10 | 15

'VARS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0818 (Fisher's exact test), Q value = 1

Table S591. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
VARS MUTATED | 0 | 4 | 1 | 1
VARS WILD-TYPE | 16 | 12 | 4 | 17

'VARS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S592. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
VARS MUTATED | 2 | 2 | 2
VARS WILD-TYPE | 24 | 10 | 16

'VARS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S593. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
VARS MUTATED | 2 | 2 | 0 | 2 | 0
VARS WILD-TYPE | 11 | 17 | 8 | 12 | 2

'VARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S594. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
VARS MUTATED | 2 | 3 | 1
VARS WILD-TYPE | 25 | 10 | 15

'VARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S595. Gene #77: 'VARS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
VARS MUTATED | 2 | 2 | 0 | 2 | 0 | 0
VARS WILD-TYPE | 7 | 15 | 7 | 10 | 6 | 5

'SHOX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 1

Table S596. Gene #78: 'SHOX2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
SHOX2 MUTATED | 2 | 0 | 0 | 0 | 1
SHOX2 WILD-TYPE | 19 | 19 | 8 | 8 | 5

'HSD17B1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S597. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
HSD17B1 MUTATED | 2 | 2 | 0 | 0 | 0
HSD17B1 WILD-TYPE | 19 | 17 | 8 | 8 | 6

'HSD17B1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.108 (Fisher's exact test), Q value = 1

Table S598. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
HSD17B1 MUTATED | 0 | 0 | 0 | 3 | 1
HSD17B1 WILD-TYPE | 13 | 8 | 14 | 11 | 6

'HSD17B1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S599. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
HSD17B1 MUTATED | 2 | 0 | 1 | 1
HSD17B1 WILD-TYPE | 15 | 8 | 13 | 15

'HSD17B1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0127 (Fisher's exact test), Q value = 1

Table S600. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
HSD17B1 MUTATED | 0 | 0 | 2 | 2
HSD17B1 WILD-TYPE | 16 | 16 | 3 | 16

Figure S50. Get High-res Image Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S601. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
HSD17B1 MUTATED | 2 | 1 | 1
HSD17B1 WILD-TYPE | 24 | 11 | 17

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S602. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
HSD17B1 MUTATED | 1 | 1 | 0 | 2 | 0
HSD17B1 WILD-TYPE | 12 | 18 | 8 | 12 | 2

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S603. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
HSD17B1 MUTATED | 2 | 1 | 1
HSD17B1 WILD-TYPE | 25 | 12 | 15

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S604. Gene #79: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
HSD17B1 MUTATED | 0 | 1 | 1 | 1 | 1 | 0
HSD17B1 WILD-TYPE | 9 | 16 | 6 | 11 | 5 | 5

'COQ2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S605. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
COQ2 MUTATED | 1 | 1 | 0 | 2 | 1
COQ2 WILD-TYPE | 20 | 18 | 8 | 6 | 5

'COQ2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S606. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
COQ2 MUTATED | 0 | 1 | 1 | 1 | 1
COQ2 WILD-TYPE | 13 | 7 | 13 | 13 | 6

'COQ2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.361 (Fisher's exact test), Q value = 1

Table S607. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
COQ2 MUTATED | 0 | 1 | 2 | 1
COQ2 WILD-TYPE | 17 | 7 | 12 | 15

'COQ2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.616 (Fisher's exact test), Q value = 1

Table S608. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
COQ2 MUTATED | 0 | 2 | 0 | 2
COQ2 WILD-TYPE | 16 | 14 | 5 | 16

'COQ2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S609. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
COQ2 MUTATED | 2 | 1 | 1
COQ2 WILD-TYPE | 24 | 11 | 17

'COQ2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.669 (Fisher's exact test), Q value = 1

Table S610. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
COQ2 MUTATED | 1 | 2 | 1 | 0 | 0
COQ2 WILD-TYPE | 12 | 17 | 7 | 14 | 2

'COQ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S611. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
COQ2 MUTATED | 2 | 1 | 1
COQ2 WILD-TYPE | 25 | 12 | 15

'COQ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S612. Gene #80: 'COQ2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
COQ2 MUTATED | 1 | 2 | 1 | 0 | 0 | 0
COQ2 WILD-TYPE | 8 | 15 | 6 | 12 | 6 | 5

'KNDC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S613. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
KNDC1 MUTATED | 2 | 4 | 2 | 1 | 1
KNDC1 WILD-TYPE | 19 | 15 | 6 | 7 | 5

'KNDC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 1

Table S614. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
KNDC1 MUTATED | 0 | 2 | 2 | 2 | 3
KNDC1 WILD-TYPE | 13 | 6 | 12 | 12 | 4

'KNDC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S615. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
KNDC1 MUTATED | 1 | 3 | 1 | 4
KNDC1 WILD-TYPE | 16 | 5 | 13 | 12

'KNDC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.372 (Fisher's exact test), Q value = 1

Table S616. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
KNDC1 MUTATED | 1 | 2 | 1 | 5
KNDC1 WILD-TYPE | 15 | 14 | 4 | 13

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.288 (Fisher's exact test), Q value = 1

Table S617. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
KNDC1 MUTATED | 2 | 3 | 4
KNDC1 WILD-TYPE | 24 | 9 | 14

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.357 (Fisher's exact test), Q value = 1

Table S618. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
KNDC1 MUTATED | 1 | 4 | 3 | 1 | 0
KNDC1 WILD-TYPE | 12 | 15 | 5 | 13 | 2

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.228 (Fisher's exact test), Q value = 1

Table S619. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
KNDC1 MUTATED | 2 | 3 | 4
KNDC1 WILD-TYPE | 25 | 10 | 12

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.749 (Fisher's exact test), Q value = 1

Table S620. Gene #81: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
KNDC1 MUTATED | 1 | 3 | 1 | 1 | 1 | 2
KNDC1 WILD-TYPE | 8 | 14 | 6 | 11 | 5 | 3

'AR MUTATION STATUS' versus 'CN_CNMF'

P value = 0.32 (Fisher's exact test), Q value = 1

Table S621. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
AR MUTATED | 2 | 0 | 0 | 1 | 1
AR WILD-TYPE | 19 | 19 | 8 | 7 | 5

'AR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 1

Table S622. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
AR MUTATED | 2 | 0 | 1 | 0 | 0
AR WILD-TYPE | 11 | 8 | 13 | 14 | 7

'AR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S623. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
AR MUTATED | 2 | 0 | 1 | 0
AR WILD-TYPE | 15 | 8 | 13 | 16

'AR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S624. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
AR MUTATED | 2 | 1 | 0 | 0
AR WILD-TYPE | 14 | 15 | 5 | 18

'AR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S625. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
AR MUTATED | 2 | 1 | 0
AR WILD-TYPE | 24 | 11 | 18

'AR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S626. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
AR MUTATED | 1 | 1 | 0 | 1 | 0
AR WILD-TYPE | 12 | 18 | 8 | 13 | 2

'AR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.596 (Fisher's exact test), Q value = 1

Table S627. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
AR MUTATED | 2 | 1 | 0
AR WILD-TYPE | 25 | 12 | 16

'AR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S628. Gene #82: 'AR MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
AR MUTATED | 1 | 1 | 0 | 1 | 0 | 0
AR WILD-TYPE | 8 | 16 | 7 | 11 | 6 | 5

'KCTD3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.414 (Fisher's exact test), Q value = 1

Table S629. Gene #83: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
KCTD3 MUTATED | 1 | 1 | 0 | 2 | 0
KCTD3 WILD-TYPE | 20 | 18 | 8 | 6 | 6

'FZD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S630. Gene #84: 'FZD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
FZD1 MUTATED | 1 | 0 | 1 | 1 | 0
FZD1 WILD-TYPE | 20 | 19 | 7 | 7 | 6

'ZC3H12D MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0033 (Fisher's exact test), Q value = 1

Table S631. Gene #85: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
ZC3H12D MUTATED | 0 | 0 | 0 | 3 | 0
ZC3H12D WILD-TYPE | 21 | 19 | 8 | 5 | 6

Figure S51. Get High-res Image Gene #85: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'KRTAP5-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.362 (Fisher's exact test), Q value = 1

Table S632. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
KRTAP5-5 MUTATED | 1 | 1 | 1 | 2 | 0
KRTAP5-5 WILD-TYPE | 20 | 18 | 7 | 6 | 6

'KRTAP5-5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S633. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
KRTAP5-5 MUTATED | 1 | 0 | 1 | 1 | 0
KRTAP5-5 WILD-TYPE | 12 | 8 | 13 | 13 | 7

'KRTAP5-5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 1

Table S634. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
KRTAP5-5 MUTATED | 2 | 1 | 0 | 0
KRTAP5-5 WILD-TYPE | 15 | 7 | 14 | 16

'KRTAP5-5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.216 (Fisher's exact test), Q value = 1

Table S635. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
KRTAP5-5 MUTATED | 1 | 1 | 1 | 0
KRTAP5-5 WILD-TYPE | 15 | 15 | 4 | 18

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S636. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
KRTAP5-5 MUTATED | 2 | 1 | 0
KRTAP5-5 WILD-TYPE | 24 | 11 | 18

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.18 (Fisher's exact test), Q value = 1

Table S637. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
KRTAP5-5 MUTATED | 0 | 1 | 0 | 1 | 1
KRTAP5-5 WILD-TYPE | 13 | 18 | 8 | 13 | 1

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S638. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
KRTAP5-5 MUTATED | 2 | 1 | 0
KRTAP5-5 WILD-TYPE | 25 | 12 | 16

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.056 (Fisher's exact test), Q value = 1

Table S639. Gene #86: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
KRTAP5-5 MUTATED | 0 | 0 | 0 | 1 | 2 | 0
KRTAP5-5 WILD-TYPE | 9 | 17 | 7 | 11 | 4 | 5

'AKAP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0745 (Fisher's exact test), Q value = 1

Table S640. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
AKAP2 MUTATED | 1 | 0 | 0 | 2 | 1
AKAP2 WILD-TYPE | 20 | 19 | 8 | 6 | 5

'AKAP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.475 (Fisher's exact test), Q value = 1

Table S641. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
AKAP2 MUTATED | 0 | 0 | 2 | 2 | 0
AKAP2 WILD-TYPE | 13 | 8 | 12 | 12 | 7

'AKAP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.738 (Fisher's exact test), Q value = 1

Table S642. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
AKAP2 MUTATED | 1 | 0 | 2 | 1
AKAP2 WILD-TYPE | 16 | 8 | 12 | 15

'AKAP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S643. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
AKAP2 MUTATED | 0 | 2 | 1 | 1
AKAP2 WILD-TYPE | 16 | 14 | 4 | 17

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S644. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
AKAP2 MUTATED | 1 | 1 | 2
AKAP2 WILD-TYPE | 25 | 11 | 16

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S645. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
AKAP2 MUTATED | 1 | 3 | 0 | 0 | 0
AKAP2 WILD-TYPE | 12 | 16 | 8 | 14 | 2

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.341 (Fisher's exact test), Q value = 1

Table S646. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
AKAP2 MUTATED | 1 | 2 | 1
AKAP2 WILD-TYPE | 26 | 11 | 15

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.647 (Fisher's exact test), Q value = 1

Table S647. Gene #87: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
AKAP2 MUTATED | 1 | 2 | 0 | 0 | 1 | 0
AKAP2 WILD-TYPE | 8 | 15 | 7 | 12 | 5 | 5

'KBTBD13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S648. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
KBTBD13 MUTATED | 5 | 3 | 0 | 1 | 0
KBTBD13 WILD-TYPE | 16 | 16 | 8 | 7 | 6

'KBTBD13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 1

Table S649. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
KBTBD13 MUTATED | 3 | 1 | 0 | 2 | 3
KBTBD13 WILD-TYPE | 10 | 7 | 14 | 12 | 4

'KBTBD13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S650. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
KBTBD13 MUTATED | 4 | 1 | 1 | 3
KBTBD13 WILD-TYPE | 13 | 7 | 13 | 13

'KBTBD13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.135 (Fisher's exact test), Q value = 1

Table S651. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
KBTBD13 MUTATED | 4 | 0 | 1 | 4
KBTBD13 WILD-TYPE | 12 | 16 | 4 | 14

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S652. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
KBTBD13 MUTATED | 4 | 2 | 3
KBTBD13 WILD-TYPE | 22 | 10 | 15

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.358 (Fisher's exact test), Q value = 1

Table S653. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
KBTBD13 MUTATED | 0 | 4 | 2 | 3 | 0
KBTBD13 WILD-TYPE | 13 | 15 | 6 | 11 | 2

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S654. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
KBTBD13 MUTATED | 4 | 2 | 3
KBTBD13 WILD-TYPE | 23 | 11 | 13

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S655. Gene #88: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
KBTBD13 MUTATED | 0 | 4 | 1 | 2 | 1 | 1
KBTBD13 WILD-TYPE | 9 | 13 | 6 | 10 | 5 | 4

'SPIRE2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S656. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
SPIRE2 MUTATED | 0 | 1 | 1 | 1 | 0
SPIRE2 WILD-TYPE | 21 | 18 | 7 | 7 | 6

'SPIRE2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0267 (Fisher's exact test), Q value = 1

Table S657. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
SPIRE2 MUTATED | 1 | 0 | 0 | 0 | 2
SPIRE2 WILD-TYPE | 12 | 8 | 14 | 14 | 5

Figure S52. Get High-res Image Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'SPIRE2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S658. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
SPIRE2 MUTATED | 1 | 0 | 1 | 1
SPIRE2 WILD-TYPE | 16 | 8 | 13 | 15

'SPIRE2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S659. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
SPIRE2 MUTATED | 1 | 0 | 0 | 2
SPIRE2 WILD-TYPE | 15 | 16 | 5 | 16

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S660. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
SPIRE2 MUTATED | 2 | 0 | 1
SPIRE2 WILD-TYPE | 24 | 12 | 17

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S661. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
SPIRE2 MUTATED | 0 | 1 | 1 | 1 | 0
SPIRE2 WILD-TYPE | 13 | 18 | 7 | 13 | 2

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S662. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
SPIRE2 MUTATED | 2 | 0 | 1
SPIRE2 WILD-TYPE | 25 | 13 | 15

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S663. Gene #89: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
SPIRE2 MUTATED | 0 | 1 | 1 | 1 | 0 | 0
SPIRE2 WILD-TYPE | 9 | 16 | 6 | 11 | 6 | 5

'NPTX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.337 (Fisher's exact test), Q value = 1

Table S664. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
NPTX1 MUTATED | 2 | 0 | 0 | 0 | 1
NPTX1 WILD-TYPE | 19 | 19 | 8 | 8 | 5

'NPTX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S665. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
NPTX1 MUTATED | 1 | 0 | 1 | 1 | 0
NPTX1 WILD-TYPE | 12 | 8 | 13 | 13 | 7

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S666. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
NPTX1 MUTATED | 1 | 0 | 1 | 1
NPTX1 WILD-TYPE | 16 | 8 | 13 | 15

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S667. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
NPTX1 MUTATED | 1 | 0 | 0 | 2
NPTX1 WILD-TYPE | 15 | 16 | 5 | 16

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S668. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
NPTX1 MUTATED | 1 | 0 | 2
NPTX1 WILD-TYPE | 25 | 12 | 16

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S669. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
NPTX1 MUTATED | 0 | 1 | 1 | 1 | 0
NPTX1 WILD-TYPE | 13 | 18 | 7 | 13 | 2

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S670. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
NPTX1 MUTATED | 1 | 0 | 2
NPTX1 WILD-TYPE | 26 | 13 | 14

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.657 (Fisher's exact test), Q value = 1

Table S671. Gene #90: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
NPTX1 MUTATED | 0 | 1 | 0 | 1 | 0 | 1
NPTX1 WILD-TYPE | 9 | 16 | 7 | 11 | 6 | 4

'ADAD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 1

Table S672. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
ADAD2 MUTATED | 1 | 0 | 1 | 1 | 1
ADAD2 WILD-TYPE | 20 | 19 | 7 | 7 | 5

'ADAD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.574 (Fisher's exact test), Q value = 1

Table S673. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
ADAD2 MUTATED | 0 | 0 | 2 | 1 | 1
ADAD2 WILD-TYPE | 13 | 8 | 12 | 13 | 6

'ADAD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.738 (Fisher's exact test), Q value = 1

Table S674. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
ADAD2 MUTATED | 1 | 0 | 2 | 1
ADAD2 WILD-TYPE | 16 | 8 | 12 | 15

'ADAD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.317 (Fisher's exact test), Q value = 1

Table S675. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
ADAD2 MUTATED | 0 | 2 | 1 | 1
ADAD2 WILD-TYPE | 16 | 14 | 4 | 17

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0206 (Fisher's exact test), Q value = 1

Table S676. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
ADAD2 MUTATED | 0 | 3 | 1
ADAD2 WILD-TYPE | 26 | 9 | 17

Figure S53. Get High-res Image Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S677. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
ADAD2 MUTATED | 0 | 3 | 0 | 1 | 0
ADAD2 WILD-TYPE | 13 | 16 | 8 | 13 | 2

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0196 (Fisher's exact test), Q value = 1

Table S678. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
ADAD2 MUTATED | 0 | 3 | 1
ADAD2 WILD-TYPE | 27 | 10 | 15

Figure S54. Get High-res Image Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S679. Gene #91: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
ADAD2 MUTATED | 0 | 2 | 0 | 1 | 1 | 0
ADAD2 WILD-TYPE | 9 | 15 | 7 | 11 | 5 | 5

'SEZ6L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S680. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
SEZ6L2 MUTATED | 3 | 3 | 0 | 0 | 2
SEZ6L2 WILD-TYPE | 18 | 16 | 8 | 8 | 4

'SEZ6L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S681. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
SEZ6L2 MUTATED | 2 | 2 | 1 | 1 | 0
SEZ6L2 WILD-TYPE | 11 | 6 | 13 | 13 | 7

'SEZ6L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S682. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
SEZ6L2 MUTATED | 2 | 0 | 2 | 2
SEZ6L2 WILD-TYPE | 15 | 8 | 12 | 14

'SEZ6L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S683. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
SEZ6L2 MUTATED | 2 | 2 | 0 | 2
SEZ6L2 WILD-TYPE | 14 | 14 | 5 | 16

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.459 (Fisher's exact test), Q value = 1

Table S684. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
SEZ6L2 MUTATED | 4 | 0 | 2
SEZ6L2 WILD-TYPE | 22 | 12 | 16

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S685. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
SEZ6L2 MUTATED | 1 | 1 | 2 | 2 | 0
SEZ6L2 WILD-TYPE | 12 | 18 | 6 | 12 | 2

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S686. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
SEZ6L2 MUTATED | 4 | 0 | 2
SEZ6L2 WILD-TYPE | 23 | 13 | 14

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.808 (Fisher's exact test), Q value = 1

Table S687. Gene #92: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
SEZ6L2 MUTATED | 1 | 1 | 1 | 2 | 0 | 1
SEZ6L2 WILD-TYPE | 8 | 16 | 6 | 10 | 6 | 4

'NEFH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0362 (Fisher's exact test), Q value = 1

Table S688. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
NEFH MUTATED | 6 | 0 | 1 | 0 | 0
NEFH WILD-TYPE | 15 | 19 | 7 | 8 | 6

Figure S55. Get High-res Image Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'NEFH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 1

Table S689. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
NEFH MUTATED | 3 | 0 | 0 | 2 | 0
NEFH WILD-TYPE | 10 | 8 | 14 | 12 | 7

'NEFH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0236 (Fisher's exact test), Q value = 1

Table S690. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
NEFH MUTATED | 4 | 0 | 0 | 0
NEFH WILD-TYPE | 13 | 8 | 14 | 16

Figure S56. Get High-res Image Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'NEFH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00825 (Fisher's exact test), Q value = 1

Table S691. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
NEFH MUTATED | 2 | 0 | 2 | 0
NEFH WILD-TYPE | 14 | 16 | 3 | 18

Figure S57. Get High-res Image Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'NEFH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.168 (Fisher's exact test), Q value = 1

Table S692. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
NEFH MUTATED | 3 | 2 | 0
NEFH WILD-TYPE | 23 | 10 | 18

'NEFH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.521 (Fisher's exact test), Q value = 1

Table S693. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
NEFH MUTATED | 1 | 1 | 0 | 3 | 0
NEFH WILD-TYPE | 12 | 18 | 8 | 11 | 2

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S694. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
NEFH MUTATED | 3 | 2 | 0
NEFH WILD-TYPE | 24 | 11 | 16

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.158 (Fisher's exact test), Q value = 1

Table S695. Gene #93: 'NEFH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
NEFH MUTATED | 1 | 0 | 0 | 3 | 1 | 0
NEFH WILD-TYPE | 8 | 17 | 7 | 9 | 5 | 5

'DLEU7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.568 (Fisher's exact test), Q value = 1

Table S696. Gene #94: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
DLEU7 MUTATED | 2 | 0 | 1 | 0 | 0
DLEU7 WILD-TYPE | 19 | 19 | 7 | 8 | 6

'AMDHD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0266 (Fisher's exact test), Q value = 1

Table S697. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
AMDHD1 MUTATED | 3 | 2 | 1 | 5 | 0
AMDHD1 WILD-TYPE | 18 | 17 | 7 | 3 | 6

Figure S58. Get High-res Image Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'AMDHD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.721 (Fisher's exact test), Q value = 1

Table S698. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
AMDHD1 MUTATED | 1 | 1 | 4 | 2 | 1
AMDHD1 WILD-TYPE | 12 | 7 | 10 | 12 | 6

'AMDHD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.569 (Fisher's exact test), Q value = 1

Table S699. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
AMDHD1 MUTATED | 3 | 2 | 3 | 1
AMDHD1 WILD-TYPE | 14 | 6 | 11 | 15

'AMDHD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 1

Table S700. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
AMDHD1 MUTATED | 1 | 4 | 2 | 2
AMDHD1 WILD-TYPE | 15 | 12 | 3 | 16

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 1

Table S701. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
AMDHD1 MUTATED | 3 | 4 | 2
AMDHD1 WILD-TYPE | 23 | 8 | 16

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S702. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
AMDHD1 MUTATED | 1 | 4 | 1 | 3 | 0
AMDHD1 WILD-TYPE | 12 | 15 | 7 | 11 | 2

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0625 (Fisher's exact test), Q value = 1

Table S703. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
AMDHD1 MUTATED | 3 | 5 | 1
AMDHD1 WILD-TYPE | 24 | 8 | 15

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.954 (Fisher's exact test), Q value = 1

Table S704. Gene #95: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
AMDHD1 MUTATED | 1 | 3 | 1 | 3 | 1 | 0
AMDHD1 WILD-TYPE | 8 | 14 | 6 | 9 | 5 | 5

'GLTSCR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.22 (Fisher's exact test), Q value = 1

Table S705. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
GLTSCR2 MUTATED | 4 | 0 | 0 | 1 | 0
GLTSCR2 WILD-TYPE | 17 | 19 | 8 | 7 | 6

'GLTSCR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.806 (Fisher's exact test), Q value = 1

Table S706. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
GLTSCR2 MUTATED | 2 | 0 | 1 | 1 | 0
GLTSCR2 WILD-TYPE | 11 | 8 | 13 | 13 | 7

'GLTSCR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.264 (Fisher's exact test), Q value = 1

Table S707. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
GLTSCR2 MUTATED | 3 | 0 | 1 | 0
GLTSCR2 WILD-TYPE | 14 | 8 | 13 | 16

'GLTSCR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.197 (Fisher's exact test), Q value = 1

Table S708. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
GLTSCR2 MUTATED | 2 | 1 | 1 | 0
GLTSCR2 WILD-TYPE | 14 | 15 | 4 | 18

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S709. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
GLTSCR2 MUTATED | 2 | 1 | 1
GLTSCR2 WILD-TYPE | 24 | 11 | 17

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.623 (Fisher's exact test), Q value = 1

Table S710. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
GLTSCR2 MUTATED | 0 | 2 | 0 | 2 | 0
GLTSCR2 WILD-TYPE | 13 | 17 | 8 | 12 | 2

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 1

Table S711. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
GLTSCR2 MUTATED | 2 | 2 | 0
GLTSCR2 WILD-TYPE | 25 | 11 | 16

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S712. Gene #96: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
GLTSCR2 MUTATED | 0 | 1 | 0 | 2 | 1 | 0
GLTSCR2 WILD-TYPE | 9 | 16 | 7 | 10 | 5 | 5

'PLEC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S713. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
PLEC MUTATED | 5 | 6 | 1 | 1 | 0
PLEC WILD-TYPE | 16 | 13 | 7 | 7 | 6

'PLEC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S714. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
PLEC MUTATED | 2 | 2 | 1 | 3 | 2
PLEC WILD-TYPE | 11 | 6 | 13 | 11 | 5

'PLEC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.194 (Fisher's exact test), Q value = 1

Table S715. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
PLEC MUTATED | 2 | 0 | 5 | 3
PLEC WILD-TYPE | 15 | 8 | 9 | 13

'PLEC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.681 (Fisher's exact test), Q value = 1

Table S716. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
PLEC MUTATED | 2 | 4 | 0 | 4
PLEC WILD-TYPE | 14 | 12 | 5 | 14

'PLEC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S717. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
PLEC MUTATED | 6 | 2 | 2
PLEC WILD-TYPE | 20 | 10 | 16

'PLEC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.604 (Fisher's exact test), Q value = 1

Table S718. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
PLEC MUTATED | 4 | 2 | 2 | 2 | 0
PLEC WILD-TYPE | 9 | 17 | 6 | 12 | 2

'PLEC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S719. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
PLEC MUTATED | 7 | 1 | 2
PLEC WILD-TYPE | 20 | 12 | 14

'PLEC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.471 (Fisher's exact test), Q value = 1

Table S720. Gene #97: 'PLEC MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
PLEC MUTATED | 2 | 2 | 3 | 2 | 0 | 1
PLEC WILD-TYPE | 7 | 15 | 4 | 10 | 6 | 4

'MAP7 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S721. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
MAP7 MUTATED | 2 | 1 | 0 | 0 | 0
MAP7 WILD-TYPE | 19 | 18 | 8 | 8 | 6

'MAP7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S722. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
MAP7 MUTATED | 1 | 0 | 0 | 1 | 1
MAP7 WILD-TYPE | 12 | 8 | 14 | 13 | 6

'MAP7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S723. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
MAP7 MUTATED | 1 | 0 | 1 | 1
MAP7 WILD-TYPE | 16 | 8 | 13 | 15

'MAP7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S724. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
MAP7 MUTATED | 1 | 0 | 0 | 2
MAP7 WILD-TYPE | 15 | 16 | 5 | 16

'MAP7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S725. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
MAP7 MUTATED | 1 | 0 | 2
MAP7 WILD-TYPE | 25 | 12 | 16

'MAP7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S726. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
MAP7 MUTATED | 0 | 1 | 1 | 1 | 0
MAP7 WILD-TYPE | 13 | 18 | 7 | 13 | 2

'MAP7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S727. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
MAP7 MUTATED | 1 | 0 | 2
MAP7 WILD-TYPE | 26 | 13 | 14

'MAP7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.655 (Fisher's exact test), Q value = 1

Table S728. Gene #98: 'MAP7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
MAP7 MUTATED | 0 | 1 | 0 | 1 | 0 | 1
MAP7 WILD-TYPE | 9 | 16 | 7 | 11 | 6 | 4

'DSPP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.928 (Fisher's exact test), Q value = 1

Table S729. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
DSPP MUTATED | 4 | 4 | 1 | 1 | 0
DSPP WILD-TYPE | 17 | 15 | 7 | 7 | 6

'DSPP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.064 (Fisher's exact test), Q value = 1

Table S730. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
DSPP MUTATED | 1 | 4 | 1 | 3 | 0
DSPP WILD-TYPE | 12 | 4 | 13 | 11 | 7

'DSPP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S731. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
DSPP MUTATED | 3 | 1 | 2 | 3
DSPP WILD-TYPE | 14 | 7 | 12 | 13

'DSPP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S732. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
DSPP MUTATED | 4 | 1 | 1 | 3
DSPP WILD-TYPE | 12 | 15 | 4 | 15

'DSPP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S733. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
DSPP MUTATED | 3 | 3 | 3
DSPP WILD-TYPE | 23 | 9 | 15

'DSPP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.574 (Fisher's exact test), Q value = 1

Table S734. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
DSPP MUTATED | 1 | 4 | 1 | 2 | 1
DSPP WILD-TYPE | 12 | 15 | 7 | 12 | 1

'DSPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.313 (Fisher's exact test), Q value = 1

Table S735. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
DSPP MUTATED | 3 | 4 | 2
DSPP WILD-TYPE | 24 | 9 | 14

'DSPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.33 (Fisher's exact test), Q value = 1

Table S736. Gene #99: 'DSPP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
DSPP MUTATED | 1 | 3 | 1 | 1 | 3 | 0
DSPP WILD-TYPE | 8 | 14 | 6 | 11 | 3 | 5

'CRIPAK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.201 (Fisher's exact test), Q value = 1

Table S737. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
CRIPAK MUTATED | 1 | 4 | 1 | 3 | 1
CRIPAK WILD-TYPE | 20 | 15 | 7 | 5 | 5

'CRIPAK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.928 (Fisher's exact test), Q value = 1

Table S738. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
CRIPAK MUTATED | 2 | 1 | 2 | 2 | 2
CRIPAK WILD-TYPE | 11 | 7 | 12 | 12 | 5

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S739. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
CRIPAK MUTATED | 2 | 0 | 3 | 4
CRIPAK WILD-TYPE | 15 | 8 | 11 | 12

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S740. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
CRIPAK MUTATED | 2 | 2 | 1 | 4
CRIPAK WILD-TYPE | 14 | 14 | 4 | 14

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.807 (Fisher's exact test), Q value = 1

Table S741. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
CRIPAK MUTATED | 5 | 1 | 3
CRIPAK WILD-TYPE | 21 | 11 | 15

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.359 (Fisher's exact test), Q value = 1

Table S742. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
CRIPAK MUTATED | 1 | 4 | 3 | 1 | 0
CRIPAK WILD-TYPE | 12 | 15 | 5 | 13 | 2

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.719 (Fisher's exact test), Q value = 1

Table S743. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
CRIPAK MUTATED | 5 | 1 | 3
CRIPAK WILD-TYPE | 22 | 12 | 13

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.287 (Fisher's exact test), Q value = 1

Table S744. Gene #100: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
CRIPAK MUTATED | 1 | 4 | 3 | 1 | 0 | 0
CRIPAK WILD-TYPE | 8 | 13 | 4 | 11 | 6 | 5

'PRKAR1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S745. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
PRKAR1A MUTATED | 2 | 1 | 1 | 2 | 0
PRKAR1A WILD-TYPE | 19 | 18 | 7 | 6 | 6

'PRKAR1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S746. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
PRKAR1A MUTATED | 1 | 1 | 2 | 1 | 1
PRKAR1A WILD-TYPE | 12 | 7 | 12 | 13 | 6

'PRKAR1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 1

Table S747. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
PRKAR1A MUTATED | 2 | 1 | 3 | 0
PRKAR1A WILD-TYPE | 15 | 7 | 11 | 16

'PRKAR1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S748. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
PRKAR1A MUTATED | 1 | 3 | 1 | 1
PRKAR1A WILD-TYPE | 15 | 13 | 4 | 17

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0865 (Fisher's exact test), Q value = 1

Table S749. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
PRKAR1A MUTATED | 5 | 1 | 0
PRKAR1A WILD-TYPE | 21 | 11 | 18

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.564 (Fisher's exact test), Q value = 1

Table S750. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
PRKAR1A MUTATED | 3 | 1 | 1 | 1 | 0
PRKAR1A WILD-TYPE | 10 | 18 | 7 | 13 | 2

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S751. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
PRKAR1A MUTATED | 5 | 1 | 0
PRKAR1A WILD-TYPE | 22 | 12 | 16

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.151 (Fisher's exact test), Q value = 1

Table S752. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
PRKAR1A MUTATED | 3 | 1 | 1 | 0 | 1 | 0
PRKAR1A WILD-TYPE | 6 | 16 | 6 | 12 | 5 | 5

'CYP4A22 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 1

Table S753. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
CYP4A22 MUTATED | 1 | 0 | 2 | 1 | 0
CYP4A22 WILD-TYPE | 20 | 19 | 6 | 7 | 6

'CYP4A22 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.622 (Fisher's exact test), Q value = 1

Table S754. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
CYP4A22 MUTATED | 1 | 1 | 2 | 0 | 0
CYP4A22 WILD-TYPE | 12 | 7 | 12 | 14 | 7

'CYP4A22 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.163 (Fisher's exact test), Q value = 1

Table S755. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
CYP4A22 MUTATED | 1 | 2 | 1 | 0
CYP4A22 WILD-TYPE | 16 | 6 | 13 | 16

'CYP4A22 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S756. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
CYP4A22 MUTATED | 2 | 2 | 0 | 0
CYP4A22 WILD-TYPE | 14 | 14 | 5 | 18

'CYP4A22 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.246 (Fisher's exact test), Q value = 1

Table S757. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
CYP4A22 MUTATED | 2 | 2 | 0
CYP4A22 WILD-TYPE | 24 | 10 | 18

'CYP4A22 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.207 (Fisher's exact test), Q value = 1

Table S758. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
CYP4A22 MUTATED | 0 | 2 | 0 | 1 | 1
CYP4A22 WILD-TYPE | 13 | 17 | 8 | 13 | 1

'CYP4A22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S759. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
CYP4A22 MUTATED | 2 | 2 | 0
CYP4A22 WILD-TYPE | 25 | 11 | 16

'CYP4A22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S760. Gene #102: 'CYP4A22 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
CYP4A22 MUTATED | 0 | 2 | 0 | 1 | 1 | 0
CYP4A22 WILD-TYPE | 9 | 15 | 7 | 11 | 5 | 5

'NOM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S761. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
NOM1 MUTATED | 2 | 2 | 1 | 1 | 0
NOM1 WILD-TYPE | 19 | 17 | 7 | 7 | 6

'NOM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.233 (Fisher's exact test), Q value = 1

Table S762. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
NOM1 MUTATED | 1 | 1 | 1 | 0 | 2
NOM1 WILD-TYPE | 12 | 7 | 13 | 14 | 5

'NOM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.93 (Fisher's exact test), Q value = 1

Table S763. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
NOM1 MUTATED | 2 | 0 | 1 | 2
NOM1 WILD-TYPE | 15 | 8 | 13 | 14

'NOM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S764. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
NOM1 MUTATED | 2 | 1 | 0 | 2
NOM1 WILD-TYPE | 14 | 15 | 5 | 16

'NOM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S765. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
NOM1 MUTATED | 2 | 1 | 2
NOM1 WILD-TYPE | 24 | 11 | 16

'NOM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.742 (Fisher's exact test), Q value = 1

Table S766. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
NOM1 MUTATED | 2 | 1 | 1 | 1 | 0
NOM1 WILD-TYPE | 11 | 18 | 7 | 13 | 2

'NOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S767. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
NOM1 MUTATED | 2 | 1 | 2
NOM1 WILD-TYPE | 25 | 12 | 14

'NOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.276 (Fisher's exact test), Q value = 1

Table S768. Gene #103: 'NOM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
NOM1 MUTATED | 2 | 1 | 0 | 0 | 1 | 1
NOM1 WILD-TYPE | 7 | 16 | 7 | 12 | 5 | 4

'RNF135 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S769. Gene #104: 'RNF135 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
RNF135 MUTATED | 1 | 2 | 0 | 0 | 0
RNF135 WILD-TYPE | 20 | 17 | 8 | 8 | 6

'C12ORF65 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.371 (Fisher's exact test), Q value = 1

Table S770. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
C12ORF65 MUTATED | 3 | 0 | 0 | 0 | 0
C12ORF65 WILD-TYPE | 18 | 19 | 8 | 8 | 6

'C12ORF65 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0354 (Fisher's exact test), Q value = 1

Table S771. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
C12ORF65 MUTATED | 3 | 0 | 0 | 0 | 0
C12ORF65 WILD-TYPE | 10 | 8 | 14 | 14 | 7

Figure S59. Get High-res Image Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'C12ORF65 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 1

Table S772. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
C12ORF65 MUTATED | 3 | 0 | 0 | 0
C12ORF65 WILD-TYPE | 14 | 8 | 14 | 16

'C12ORF65 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0623 (Fisher's exact test), Q value = 1

Table S773. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
C12ORF65 MUTATED | 3 | 0 | 0 | 0
C12ORF65 WILD-TYPE | 13 | 16 | 5 | 18

'C12ORF65 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S774. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
C12ORF65 MUTATED | 2 | 1 | 0
C12ORF65 WILD-TYPE | 24 | 11 | 18

'C12ORF65 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S775. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
C12ORF65 MUTATED | 0 | 1 | 0 | 2 | 0
C12ORF65 WILD-TYPE | 13 | 18 | 8 | 12 | 2

'C12ORF65 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S776. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
C12ORF65 MUTATED | 2 | 1 | 0
C12ORF65 WILD-TYPE | 25 | 12 | 16

'C12ORF65 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.735 (Fisher's exact test), Q value = 1

Table S777. Gene #105: 'C12ORF65 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
C12ORF65 MUTATED | 0 | 1 | 0 | 2 | 0 | 0
C12ORF65 WILD-TYPE | 9 | 16 | 7 | 10 | 6 | 5

'HLA-B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.293 (Fisher's exact test), Q value = 1

Table S778. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
HLA-B MUTATED | 1 | 1 | 1 | 2 | 1
HLA-B WILD-TYPE | 20 | 18 | 7 | 6 | 5

'HLA-B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S779. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
HLA-B MUTATED | 2 | 0 | 2 | 2 | 0
HLA-B WILD-TYPE | 11 | 8 | 12 | 12 | 7

'HLA-B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S780. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
HLA-B MUTATED | 2 | 0 | 2 | 2
HLA-B WILD-TYPE | 15 | 8 | 12 | 14

'HLA-B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S781. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
HLA-B MUTATED | 2 | 2 | 0 | 2
HLA-B WILD-TYPE | 14 | 14 | 5 | 16

'HLA-B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.653 (Fisher's exact test), Q value = 1

Table S782. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
HLA-B MUTATED | 2 | 1 | 3
HLA-B WILD-TYPE | 24 | 11 | 15

'HLA-B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.274 (Fisher's exact test), Q value = 1

Table S783. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
HLA-B MUTATED | 3 | 3 | 0 | 0 | 0
HLA-B WILD-TYPE | 10 | 16 | 8 | 14 | 2

'HLA-B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.535 (Fisher's exact test), Q value = 1

Table S784. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
HLA-B MUTATED | 2 | 1 | 3
HLA-B WILD-TYPE | 25 | 12 | 13

'HLA-B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.319 (Fisher's exact test), Q value = 1

Table S785. Gene #106: 'HLA-B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
HLA-B MUTATED | 2 | 3 | 0 | 0 | 0 | 1
HLA-B WILD-TYPE | 7 | 14 | 7 | 12 | 6 | 4

'CSGALNACT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S786. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
CSGALNACT2 MUTATED | 1 | 2 | 0 | 0 | 0
CSGALNACT2 WILD-TYPE | 20 | 17 | 8 | 8 | 6

'CSGALNACT2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0256 (Fisher's exact test), Q value = 1

Table S787. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
CSGALNACT2 MUTATED | 1 | 0 | 0 | 0 | 2
CSGALNACT2 WILD-TYPE | 12 | 8 | 14 | 14 | 5

Figure S60. Get High-res Image Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.691 (Fisher's exact test), Q value = 1

Table S788. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
CSGALNACT2 MUTATED | 1 | 0 | 0 | 2
CSGALNACT2 WILD-TYPE | 16 | 8 | 14 | 14

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S789. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
CSGALNACT2 MUTATED | 1 | 0 | 0 | 2
CSGALNACT2 WILD-TYPE | 15 | 16 | 5 | 16

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S790. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
CSGALNACT2 MUTATED | 1 | 0 | 2
CSGALNACT2 WILD-TYPE | 25 | 12 | 16

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S791. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
CSGALNACT2 MUTATED | 0 | 2 | 0 | 1 | 0
CSGALNACT2 WILD-TYPE | 13 | 17 | 8 | 13 | 2

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S792. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
CSGALNACT2 MUTATED | 1 | 0 | 2
CSGALNACT2 WILD-TYPE | 26 | 13 | 14

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.933 (Fisher's exact test), Q value = 1

Table S793. Gene #107: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
CSGALNACT2 MUTATED | 0 | 2 | 0 | 1 | 0 | 0
CSGALNACT2 WILD-TYPE | 9 | 15 | 7 | 11 | 6 | 5

'UQCRFS1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 1

Table S794. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
UQCRFS1 MUTATED | 1 | 1 | 1 | 0 | 1
UQCRFS1 WILD-TYPE | 20 | 18 | 7 | 8 | 5

'UQCRFS1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.502 (Fisher's exact test), Q value = 1

Table S795. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
UQCRFS1 MUTATED | 2 | 1 | 2 | 0 | 0
UQCRFS1 WILD-TYPE | 11 | 7 | 12 | 14 | 7

'UQCRFS1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S796. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
UQCRFS1 MUTATED | 1 | 1 | 1 | 1
UQCRFS1 WILD-TYPE | 16 | 7 | 13 | 15

'UQCRFS1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S797. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
UQCRFS1 MUTATED | 1 | 2 | 0 | 1
UQCRFS1 WILD-TYPE | 15 | 14 | 5 | 17

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.49 (Fisher's exact test), Q value = 1

Table S798. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
UQCRFS1 MUTATED | 4 | 0 | 1
UQCRFS1 WILD-TYPE | 22 | 12 | 17

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.187 (Fisher's exact test), Q value = 1

Table S799. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
UQCRFS1 MUTATED | 3 | 0 | 1 | 1 | 0
UQCRFS1 WILD-TYPE | 10 | 19 | 7 | 13 | 2

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.494 (Fisher's exact test), Q value = 1

Table S800. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
UQCRFS1 MUTATED | 4 | 0 | 1
UQCRFS1 WILD-TYPE | 23 | 13 | 15

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0508 (Fisher's exact test), Q value = 1

Table S801. Gene #108: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
UQCRFS1 MUTATED | 3 | 0 | 0 | 1 | 0 | 1
UQCRFS1 WILD-TYPE | 6 | 17 | 7 | 11 | 6 | 4

'PDCD6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S802. Gene #109: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
PDCD6 MUTATED | 0 | 1 | 1 | 1 | 0
PDCD6 WILD-TYPE | 21 | 18 | 7 | 7 | 6

'PDCD6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.699 (Fisher's exact test), Q value = 1

Table S803. Gene #109: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
PDCD6 MUTATED | 1 | 0 | 0 | 1 | 1
PDCD6 WILD-TYPE | 12 | 8 | 14 | 13 | 6

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S804. Gene #109: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
PDCD6 MUTATED | 2 | 0 | 1
PDCD6 WILD-TYPE | 24 | 12 | 17

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.632 (Fisher's exact test), Q value = 1

Table S805. Gene #109: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
PDCD6 MUTATED | 1 | 1 | 1 | 0 | 0
PDCD6 WILD-TYPE | 12 | 18 | 7 | 14 | 2

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S806. Gene #109: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
PDCD6 MUTATED | 2 | 0 | 1
PDCD6 WILD-TYPE | 25 | 13 | 15

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S807. Gene #109: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
PDCD6 MUTATED | 1 | 1 | 1 | 0 | 0 | 0
PDCD6 WILD-TYPE | 8 | 16 | 6 | 12 | 6 | 5

'PTX4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.568 (Fisher's exact test), Q value = 1

Table S808. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
PTX4 MUTATED | 2 | 0 | 0 | 1 | 0
PTX4 WILD-TYPE | 19 | 19 | 8 | 7 | 6

'PTX4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S809. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
PTX4 MUTATED | 1 | 0 | 1 | 1 | 0
PTX4 WILD-TYPE | 12 | 8 | 13 | 13 | 7

'PTX4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S810. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
PTX4 MUTATED | 2 | 0 | 1 | 0
PTX4 WILD-TYPE | 15 | 8 | 13 | 16

'PTX4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.217 (Fisher's exact test), Q value = 1

Table S811. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
PTX4 MUTATED | 1 | 1 | 1 | 0
PTX4 WILD-TYPE | 15 | 15 | 4 | 18

'PTX4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S812. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
PTX4 MUTATED | 2 | 1 | 0
PTX4 WILD-TYPE | 24 | 11 | 18

'PTX4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S813. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
PTX4 MUTATED | 1 | 1 | 0 | 1 | 0
PTX4 WILD-TYPE | 12 | 18 | 8 | 13 | 2

'PTX4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.595 (Fisher's exact test), Q value = 1

Table S814. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
PTX4 MUTATED | 2 | 1 | 0
PTX4 WILD-TYPE | 25 | 12 | 16

'PTX4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.392 (Fisher's exact test), Q value = 1

Table S815. Gene #110: 'PTX4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
PTX4 MUTATED | 1 | 0 | 0 | 1 | 1 | 0
PTX4 WILD-TYPE | 8 | 17 | 7 | 11 | 5 | 5

'SGK223 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S816. Gene #111: 'SGK223 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
SGK223 MUTATED | 1 | 2 | 0 | 0 | 0
SGK223 WILD-TYPE | 20 | 17 | 8 | 8 | 6

'POLRMT MUTATION STATUS' versus 'CN_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 1

Table S817. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
POLRMT MUTATED | 1 | 1 | 0 | 1 | 1
POLRMT WILD-TYPE | 20 | 18 | 8 | 7 | 5

'POLRMT MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0363 (Fisher's exact test), Q value = 1

Table S818. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
POLRMT MUTATED | 0 | 0 | 0 | 2 | 2
POLRMT WILD-TYPE | 13 | 8 | 14 | 12 | 5

Figure S61. Get High-res Image Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'POLRMT MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.327 (Fisher's exact test), Q value = 1

Table S819. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
POLRMT MUTATED | 0 | 0 | 2 | 2
POLRMT WILD-TYPE | 17 | 8 | 12 | 14

'POLRMT MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0737 (Fisher's exact test), Q value = 1

Table S820. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
POLRMT MUTATED | 0 | 0 | 0 | 4
POLRMT WILD-TYPE | 16 | 16 | 5 | 14

'POLRMT MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.189 (Fisher's exact test), Q value = 1

Table S821. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
POLRMT MUTATED | 1 | 0 | 3
POLRMT WILD-TYPE | 25 | 12 | 15

'POLRMT MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S822. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
POLRMT MUTATED | 0 | 3 | 1 | 0 | 0
POLRMT WILD-TYPE | 13 | 16 | 7 | 14 | 2

'POLRMT MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S823. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
POLRMT MUTATED | 1 | 0 | 3
POLRMT WILD-TYPE | 26 | 13 | 13

'POLRMT MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S824. Gene #112: 'POLRMT MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
POLRMT MUTATED | 0 | 3 | 1 | 0 | 0 | 0
POLRMT WILD-TYPE | 9 | 14 | 6 | 12 | 6 | 5

'CACNA1D MUTATION STATUS' versus 'CN_CNMF'

P value = 0.566 (Fisher's exact test), Q value = 1

Table S825. Gene #113: 'CACNA1D MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
CACNA1D MUTATED | 2 | 0 | 0 | 1 | 0
CACNA1D WILD-TYPE | 19 | 19 | 8 | 7 | 6

'NF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.152 (Fisher's exact test), Q value = 1

Table S826. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
NF1 MUTATED | 3 | 1 | 0 | 3 | 0
NF1 WILD-TYPE | 18 | 18 | 8 | 5 | 6

'NF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S827. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
NF1 MUTATED | 2 | 0 | 2 | 2 | 1
NF1 WILD-TYPE | 11 | 8 | 12 | 12 | 6

'NF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.41 (Fisher's exact test), Q value = 1

Table S828. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
NF1 MUTATED | 4 | 0 | 2 | 1
NF1 WILD-TYPE | 13 | 8 | 12 | 15

'NF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.268 (Fisher's exact test), Q value = 1

Table S829. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
NF1 MUTATED | 2 | 2 | 2 | 1
NF1 WILD-TYPE | 14 | 14 | 3 | 17

'NF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S830. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
NF1 MUTATED | 2 | 3 | 2
NF1 WILD-TYPE | 24 | 9 | 16

'NF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S831. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
NF1 MUTATED | 1 | 2 | 1 | 3 | 0
NF1 WILD-TYPE | 12 | 17 | 7 | 11 | 2

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0999 (Fisher's exact test), Q value = 1

Table S832. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
NF1 MUTATED | 2 | 4 | 1
NF1 WILD-TYPE | 25 | 9 | 15

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.527 (Fisher's exact test), Q value = 1

Table S833. Gene #114: 'NF1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
NF1 MUTATED | 1 | 1 | 0 | 3 | 1 | 1
NF1 WILD-TYPE | 8 | 16 | 7 | 9 | 5 | 4

'RGMB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S834. Gene #115: 'RGMB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
RGMB MUTATED | 2 | 2 | 2 | 0 | 0
RGMB WILD-TYPE | 19 | 17 | 6 | 8 | 6

'ADAMTS7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.14 (Fisher's exact test), Q value = 1

Table S835. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
ADAMTS7 MUTATED | 0 | 3 | 0 | 0 | 1
ADAMTS7 WILD-TYPE | 21 | 16 | 8 | 8 | 5

'ADAMTS7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.575 (Fisher's exact test), Q value = 1

Table S836. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
ADAMTS7 MUTATED | 0 | 0 | 1 | 2 | 1
ADAMTS7 WILD-TYPE | 13 | 8 | 13 | 12 | 6

'ADAMTS7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0732 (Fisher's exact test), Q value = 1

Table S837. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
ADAMTS7 MUTATED | 0 | 1 | 0 | 3
ADAMTS7 WILD-TYPE | 17 | 7 | 14 | 13

'ADAMTS7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S838. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
ADAMTS7 MUTATED | 0 | 1 | 0 | 3
ADAMTS7 WILD-TYPE | 16 | 15 | 5 | 15

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.061 (Fisher's exact test), Q value = 1

Table S839. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
ADAMTS7 MUTATED | 0 | 1 | 3
ADAMTS7 WILD-TYPE | 26 | 11 | 15

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S840. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
ADAMTS7 MUTATED | 0 | 3 | 1 | 0 | 0
ADAMTS7 WILD-TYPE | 13 | 16 | 7 | 14 | 2

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.038 (Fisher's exact test), Q value = 1

Table S841. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
ADAMTS7 MUTATED | 0 | 1 | 3
ADAMTS7 WILD-TYPE | 27 | 12 | 13

Figure S62. Get High-res Image Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 1

Table S842. Gene #116: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
ADAMTS7 MUTATED | 0 | 3 | 0 | 0 | 0 | 1
ADAMTS7 WILD-TYPE | 9 | 14 | 7 | 12 | 6 | 4

'CLIC6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S843. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
CLIC6 MUTATED | 3 | 2 | 0 | 1 | 0
CLIC6 WILD-TYPE | 18 | 17 | 8 | 7 | 6

'CLIC6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S844. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
CLIC6 MUTATED | 1 | 1 | 1 | 1 | 0
CLIC6 WILD-TYPE | 12 | 7 | 13 | 13 | 7

'CLIC6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S845. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
CLIC6 MUTATED | 2 | 1 | 0 | 1
CLIC6 WILD-TYPE | 15 | 7 | 14 | 15

'CLIC6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.193 (Fisher's exact test), Q value = 1

Table S846. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
CLIC6 MUTATED | 2 | 1 | 1 | 0
CLIC6 WILD-TYPE | 14 | 15 | 4 | 18

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.246 (Fisher's exact test), Q value = 1

Table S847. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
CLIC6 MUTATED | 2 | 2 | 0
CLIC6 WILD-TYPE | 24 | 10 | 18

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.579 (Fisher's exact test), Q value = 1

Table S848. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
CLIC6 MUTATED | 0 | 1 | 1 | 2 | 0
CLIC6 WILD-TYPE | 13 | 18 | 7 | 12 | 2

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.248 (Fisher's exact test), Q value = 1

Table S849. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
CLIC6 MUTATED | 2 | 2 | 0
CLIC6 WILD-TYPE | 25 | 11 | 16

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S850. Gene #117: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
CLIC6 MUTATED | 0 | 1 | 1 | 1 | 1 | 0
CLIC6 WILD-TYPE | 9 | 16 | 6 | 11 | 5 | 5

'EMR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.375 (Fisher's exact test), Q value = 1

Table S851. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
EMR2 MUTATED | 0 | 2 | 1 | 1 | 0
EMR2 WILD-TYPE | 21 | 17 | 7 | 7 | 6

'EMR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S852. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
EMR2 MUTATED | 0 | 0 | 3 | 1 | 0
EMR2 WILD-TYPE | 13 | 8 | 11 | 13 | 7

'EMR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 1

Table S853. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
EMR2 MUTATED | 0 | 1 | 1 | 2
EMR2 WILD-TYPE | 17 | 7 | 13 | 14

'EMR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S854. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
EMR2 MUTATED | 0 | 2 | 0 | 2
EMR2 WILD-TYPE | 16 | 14 | 5 | 16

'EMR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.674 (Fisher's exact test), Q value = 1

Table S855. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
EMR2 MUTATED | 1 | 1 | 2
EMR2 WILD-TYPE | 25 | 11 | 16

'EMR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.207 (Fisher's exact test), Q value = 1

Table S856. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
EMR2 MUTATED | 0 | 2 | 0 | 1 | 1
EMR2 WILD-TYPE | 13 | 17 | 8 | 13 | 1

'EMR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S857. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
EMR2 MUTATED | 1 | 1 | 2
EMR2 WILD-TYPE | 26 | 12 | 14

'EMR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S858. Gene #118: 'EMR2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
EMR2 MUTATED | 0 | 2 | 0 | 1 | 1 | 0
EMR2 WILD-TYPE | 9 | 15 | 7 | 11 | 5 | 5

'PCDHB13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.513 (Fisher's exact test), Q value = 1

Table S859. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
PCDHB13 MUTATED | 1 | 1 | 1 | 1 | 1
PCDHB13 WILD-TYPE | 20 | 18 | 7 | 7 | 5

'PCDHB13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.139 (Fisher's exact test), Q value = 1

Table S860. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
PCDHB13 MUTATED | 0 | 1 | 3 | 0 | 0
PCDHB13 WILD-TYPE | 13 | 7 | 11 | 14 | 7

'PCDHB13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 1

Table S861. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
PCDHB13 MUTATED | 0 | 0 | 3 | 1
PCDHB13 WILD-TYPE | 17 | 8 | 11 | 15

'PCDHB13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.256 (Fisher's exact test), Q value = 1

Table S862. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
PCDHB13 MUTATED | 0 | 3 | 0 | 1
PCDHB13 WILD-TYPE | 16 | 13 | 5 | 17

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S863. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
PCDHB13 MUTATED | 3 | 0 | 1
PCDHB13 WILD-TYPE | 23 | 12 | 17

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0566 (Fisher's exact test), Q value = 1

Table S864. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
PCDHB13 MUTATED | 3 | 0 | 1 | 0 | 0
PCDHB13 WILD-TYPE | 10 | 19 | 7 | 14 | 2

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S865. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
PCDHB13 MUTATED | 3 | 0 | 1
PCDHB13 WILD-TYPE | 24 | 13 | 15

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0126 (Fisher's exact test), Q value = 1

Table S866. Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
PCDHB13 MUTATED | 3 | 0 | 0 | 0 | 0 | 1
PCDHB13 WILD-TYPE | 6 | 17 | 7 | 12 | 6 | 4

Figure S63. Get High-res Image Gene #119: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MTFMT MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S867. Gene #120: 'MTFMT MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
MTFMT MUTATED | 2 | 1 | 0 | 0 | 0
MTFMT WILD-TYPE | 19 | 18 | 8 | 8 | 6

'SPTAN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.244 (Fisher's exact test), Q value = 1

Table S868. Gene #121: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
SPTAN1 MUTATED | 1 | 0 | 0 | 1 | 1
SPTAN1 WILD-TYPE | 20 | 19 | 8 | 7 | 5

'HLA-A MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S869. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
HLA-A MUTATED | 2 | 1 | 0 | 0 | 0
HLA-A WILD-TYPE | 19 | 18 | 8 | 8 | 6

'HLA-A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S870. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
HLA-A MUTATED | 1 | 0 | 1 | 1 | 0
HLA-A WILD-TYPE | 12 | 8 | 13 | 13 | 7

'HLA-A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S871. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
HLA-A MUTATED | 1 | 1 | 0 | 1
HLA-A WILD-TYPE | 16 | 7 | 14 | 15

'HLA-A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.219 (Fisher's exact test), Q value = 1

Table S872. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
HLA-A MUTATED | 1 | 1 | 1 | 0
HLA-A WILD-TYPE | 15 | 15 | 4 | 18

'HLA-A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S873. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
HLA-A MUTATED | 2 | 0 | 1
HLA-A WILD-TYPE | 24 | 12 | 17

'HLA-A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S874. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
HLA-A MUTATED | 1 | 0 | 1 | 1 | 0
HLA-A WILD-TYPE | 12 | 19 | 7 | 13 | 2

'HLA-A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S875. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
HLA-A MUTATED | 2 | 0 | 1
HLA-A WILD-TYPE | 25 | 13 | 15

'HLA-A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.215 (Fisher's exact test), Q value = 1

Table S876. Gene #122: 'HLA-A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
HLA-A MUTATED | 0 | 0 | 1 | 1 | 0 | 1
HLA-A WILD-TYPE | 9 | 17 | 6 | 11 | 6 | 4

'ASB16 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S877. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
ASB16 MUTATED | 1 | 2 | 1 | 1 | 1
ASB16 WILD-TYPE | 20 | 17 | 7 | 7 | 5

'ASB16 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.945 (Fisher's exact test), Q value = 1

Table S878. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
ASB16 MUTATED | 1 | 0 | 1 | 1 | 1
ASB16 WILD-TYPE | 12 | 8 | 13 | 13 | 6

'ASB16 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S879. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
ASB16 MUTATED | 1 | 1 | 0 | 2
ASB16 WILD-TYPE | 16 | 7 | 14 | 14

'ASB16 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S880. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
ASB16 MUTATED | 1 | 2 | 0 | 1
ASB16 WILD-TYPE | 15 | 14 | 5 | 17

'ASB16 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.543 (Fisher's exact test), Q value = 1

Table S881. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
ASB16 MUTATED | 3 | 0 | 1
ASB16 WILD-TYPE | 23 | 12 | 17

'ASB16 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S882. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
ASB16 MUTATED | 2 | 1 | 0 | 1 | 0
ASB16 WILD-TYPE | 11 | 18 | 8 | 13 | 2

'ASB16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S883. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
ASB16 MUTATED | 3 | 0 | 1
ASB16 WILD-TYPE | 24 | 13 | 15

'ASB16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.959 (Fisher's exact test), Q value = 1

Table S884. Gene #123: 'ASB16 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
ASB16 MUTATED | 1 | 1 | 1 | 1 | 0 | 0
ASB16 WILD-TYPE | 8 | 16 | 6 | 11 | 6 | 5

'GPRIN2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S885. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
GPRIN2 MUTATED | 2 | 3 | 2 | 2 | 0
GPRIN2 WILD-TYPE | 19 | 16 | 6 | 6 | 6

'GPRIN2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.37 (Fisher's exact test), Q value = 1

Table S886. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
GPRIN2 MUTATED | 1 | 0 | 4 | 1 | 1
GPRIN2 WILD-TYPE | 12 | 8 | 10 | 13 | 6

'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S887. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
GPRIN2 MUTATED | 1 | 1 | 3 | 2
GPRIN2 WILD-TYPE | 16 | 7 | 11 | 14

'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S888. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
GPRIN2 MUTATED | 1 | 4 | 0 | 2
GPRIN2 WILD-TYPE | 15 | 12 | 5 | 16

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.582 (Fisher's exact test), Q value = 1

Table S889. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
GPRIN2 MUTATED | 2 | 2 | 3
GPRIN2 WILD-TYPE | 24 | 10 | 15

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S890. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
GPRIN2 MUTATED | 1 | 4 | 1 | 1 | 0
GPRIN2 WILD-TYPE | 12 | 15 | 7 | 13 | 2

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S891. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
GPRIN2 MUTATED | 2 | 3 | 2
GPRIN2 WILD-TYPE | 25 | 10 | 14

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.647 (Fisher's exact test), Q value = 1

Table S892. Gene #124: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
GPRIN2 MUTATED | 1 | 4 | 0 | 1 | 0 | 1
GPRIN2 WILD-TYPE | 8 | 13 | 7 | 11 | 6 | 4

'HNRNPCL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.336 (Fisher's exact test), Q value = 1

Table S893. Gene #125: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
HNRNPCL1 MUTATED | 2 | 0 | 0 | 0 | 1
HNRNPCL1 WILD-TYPE | 19 | 19 | 8 | 8 | 5

'BTNL9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.416 (Fisher's exact test), Q value = 1

Table S894. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
BTNL9 MUTATED | 1 | 1 | 0 | 2 | 0
BTNL9 WILD-TYPE | 20 | 18 | 8 | 6 | 6

'BTNL9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0962 (Fisher's exact test), Q value = 1

Table S895. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
BTNL9 MUTATED | 0 | 0 | 3 | 0 | 0
BTNL9 WILD-TYPE | 13 | 8 | 11 | 14 | 7

'BTNL9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S896. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
BTNL9 MUTATED | 0 | 1 | 2 | 0
BTNL9 WILD-TYPE | 17 | 7 | 12 | 16

'BTNL9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0618 (Fisher's exact test), Q value = 1

Table S897. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
BTNL9 MUTATED | 0 | 3 | 0 | 0
BTNL9 WILD-TYPE | 16 | 13 | 5 | 18

'BTNL9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.142 (Fisher's exact test), Q value = 1

Table S898. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
BTNL9 MUTATED | 1 | 2 | 0
BTNL9 WILD-TYPE | 25 | 10 | 18

'BTNL9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S899. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
BTNL9 MUTATED | 1 | 1 | 0 | 1 | 0
BTNL9 WILD-TYPE | 12 | 18 | 8 | 13 | 2

'BTNL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 1

Table S900. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
BTNL9 MUTATED | 1 | 2 | 0
BTNL9 WILD-TYPE | 26 | 11 | 16

'BTNL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S901. Gene #126: 'BTNL9 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
BTNL9 MUTATED | 1 | 1 | 0 | 1 | 0 | 0
BTNL9 WILD-TYPE | 8 | 16 | 7 | 11 | 6 | 5

'KCNJ11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0135 (Fisher's exact test), Q value = 1

Table S902. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
KCNJ11 MUTATED | 0 | 1 | 3 | 0 | 0
KCNJ11 WILD-TYPE | 21 | 18 | 5 | 8 | 6

Figure S64. Get High-res Image Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'KCNJ11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S903. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
KCNJ11 MUTATED | 1 | 1 | 2 | 0 | 0
KCNJ11 WILD-TYPE | 12 | 7 | 12 | 14 | 7

'KCNJ11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S904. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
KCNJ11 MUTATED | 1 | 1 | 2 | 0
KCNJ11 WILD-TYPE | 16 | 7 | 12 | 16

'KCNJ11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.14 (Fisher's exact test), Q value = 1

Table S905. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
KCNJ11 MUTATED | 1 | 3 | 0 | 0
KCNJ11 WILD-TYPE | 15 | 13 | 5 | 18

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 1

Table S906. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
KCNJ11 MUTATED | 4 | 0 | 0
KCNJ11 WILD-TYPE | 22 | 12 | 18

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0498 (Fisher's exact test), Q value = 1

Table S907. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
KCNJ11 MUTATED | 2 | 0 | 0 | 1 | 1
KCNJ11 WILD-TYPE | 11 | 19 | 8 | 13 | 1

Figure S65. Get High-res Image Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S908. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
KCNJ11 MUTATED | 4 | 0 | 0
KCNJ11 WILD-TYPE | 23 | 13 | 16

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.211 (Fisher's exact test), Q value = 1

Table S909. Gene #127: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
KCNJ11 MUTATED | 2 | 0 | 0 | 1 | 1 | 0
KCNJ11 WILD-TYPE | 7 | 17 | 7 | 11 | 5 | 5

'JMJD4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S910. Gene #128: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
JMJD4 MUTATED | 1 | 1 | 1 | 0 | 0
JMJD4 WILD-TYPE | 20 | 18 | 7 | 8 | 6

'LRRC4B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.188 (Fisher's exact test), Q value = 1

Table S911. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
LRRC4B MUTATED | 3 | 0 | 2 | 1 | 0
LRRC4B WILD-TYPE | 18 | 19 | 6 | 7 | 6

'LRRC4B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.189 (Fisher's exact test), Q value = 1

Table S912. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
LRRC4B MUTATED | 4 | 0 | 1 | 1 | 0
LRRC4B WILD-TYPE | 9 | 8 | 13 | 13 | 7

'LRRC4B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0133 (Fisher's exact test), Q value = 1

Table S913. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
LRRC4B MUTATED | 5 | 1 | 0 | 0
LRRC4B WILD-TYPE | 12 | 7 | 14 | 16

Figure S66. Get High-res Image Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'LRRC4B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0708 (Fisher's exact test), Q value = 1

Table S914. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
LRRC4B MUTATED | 4 | 1 | 1 | 0
LRRC4B WILD-TYPE | 12 | 15 | 4 | 18

'LRRC4B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S915. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
LRRC4B MUTATED | 4 | 2 | 0
LRRC4B WILD-TYPE | 22 | 10 | 18

'LRRC4B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0299 (Fisher's exact test), Q value = 1

Table S916. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
LRRC4B MUTATED | 0 | 1 | 0 | 4 | 1
LRRC4B WILD-TYPE | 13 | 18 | 8 | 10 | 1

Figure S67. Get High-res Image Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'LRRC4B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S917. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
LRRC4B MUTATED | 5 | 1 | 0
LRRC4B WILD-TYPE | 22 | 12 | 16

'LRRC4B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00974 (Fisher's exact test), Q value = 1

Table S918. Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
LRRC4B MUTATED | 0 | 0 | 0 | 4 | 2 | 0
LRRC4B WILD-TYPE | 9 | 17 | 7 | 8 | 4 | 5

Figure S68. Get High-res Image Gene #129: 'LRRC4B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'OPLAH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.566 (Fisher's exact test), Q value = 1

Table S919. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
OPLAH MUTATED | 2 | 0 | 1 | 0 | 0
OPLAH WILD-TYPE | 19 | 19 | 7 | 8 | 6

'OPLAH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S920. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
OPLAH MUTATED | 1 | 1 | 1 | 0 | 0
OPLAH WILD-TYPE | 12 | 7 | 13 | 14 | 7

'OPLAH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S921. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
OPLAH MUTATED | 2 | 0 | 1 | 0
OPLAH WILD-TYPE | 15 | 8 | 13 | 16

'OPLAH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S922. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
OPLAH MUTATED | 2 | 1 | 0 | 0
OPLAH WILD-TYPE | 14 | 15 | 5 | 18

'OPLAH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S923. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
OPLAH MUTATED | 2 | 1 | 0
OPLAH WILD-TYPE | 24 | 11 | 18

'OPLAH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S924. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
OPLAH MUTATED | 1 | 0 | 0 | 2 | 0
OPLAH WILD-TYPE | 12 | 19 | 8 | 12 | 2

'OPLAH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S925. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
OPLAH MUTATED | 2 | 1 | 0
OPLAH WILD-TYPE | 25 | 12 | 16

'OPLAH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S926. Gene #130: 'OPLAH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
OPLAH MUTATED | 1 | 0 | 0 | 1 | 1 | 0
OPLAH WILD-TYPE | 8 | 17 | 7 | 11 | 5 | 5

'BAGE2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S927. Gene #131: 'BAGE2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
BAGE2 MUTATED | 1 | 2 | 0 | 0 | 0
BAGE2 WILD-TYPE | 20 | 17 | 8 | 8 | 6

'MADCAM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S928. Gene #132: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
MADCAM1 MUTATED | 0 | 2 | 1 | 0 | 0
MADCAM1 WILD-TYPE | 21 | 17 | 7 | 8 | 6

'MADCAM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S929. Gene #132: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
MADCAM1 MUTATED | 1 | 0 | 0 | 1 | 1
MADCAM1 WILD-TYPE | 12 | 8 | 14 | 13 | 6

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S930. Gene #132: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
MADCAM1 MUTATED | 2 | 0 | 1
MADCAM1 WILD-TYPE | 24 | 12 | 17

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S931. Gene #132: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
MADCAM1 MUTATED | 2 | 0 | 1 | 0 | 0
MADCAM1 WILD-TYPE | 11 | 19 | 7 | 14 | 2

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S932. Gene #132: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
MADCAM1 MUTATED | 2 | 0 | 1
MADCAM1 WILD-TYPE | 25 | 13 | 15

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.136 (Fisher's exact test), Q value = 1

Table S933. Gene #132: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
MADCAM1 MUTATED | 1 | 0 | 1 | 0 | 0 | 1
MADCAM1 WILD-TYPE | 8 | 17 | 6 | 12 | 6 | 4

'CTBP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S934. Gene #133: 'CTBP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
CTBP2 MUTATED | 1 | 2 | 0 | 0 | 0
CTBP2 WILD-TYPE | 20 | 17 | 8 | 8 | 6

'MSH3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0176 (Fisher's exact test), Q value = 1

Table S935. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
MSH3 MUTATED | 1 | 0 | 0 | 3 | 0
MSH3 WILD-TYPE | 20 | 19 | 8 | 5 | 6

Figure S69. Get High-res Image Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'MSH3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.7 (Fisher's exact test), Q value = 1

Table S936. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
MSH3 MUTATED | 1 | 0 | 1 | 0 | 1
MSH3 WILD-TYPE | 12 | 8 | 13 | 14 | 6

'MSH3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.335 (Fisher's exact test), Q value = 1

Table S937. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
MSH3 MUTATED | 1 | 0 | 2 | 0
MSH3 WILD-TYPE | 16 | 8 | 12 | 16

'MSH3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S938. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
MSH3 MUTATED | 1 | 1 | 0 | 1
MSH3 WILD-TYPE | 15 | 15 | 5 | 17

'MSH3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S939. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
MSH3 MUTATED | 3 | 0 | 0
MSH3 WILD-TYPE | 23 | 12 | 18

'MSH3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S940. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
MSH3 MUTATED | 1 | 0 | 1 | 1 | 0
MSH3 WILD-TYPE | 12 | 19 | 7 | 13 | 2

'MSH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S941. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
MSH3 MUTATED | 3 | 0 | 0
MSH3 WILD-TYPE | 24 | 13 | 16

'MSH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.495 (Fisher's exact test), Q value = 1

Table S942. Gene #134: 'MSH3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
MSH3 MUTATED | 1 | 0 | 1 | 1 | 0 | 0
MSH3 WILD-TYPE | 8 | 17 | 6 | 11 | 6 | 5

'ATN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 1

Table S943. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
ATN1 MUTATED | 0 | 2 | 0 | 2 | 0
ATN1 WILD-TYPE | 21 | 17 | 8 | 6 | 6

'ATN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S944. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
ATN1 MUTATED | 1 | 1 | 0 | 1 | 0
ATN1 WILD-TYPE | 12 | 7 | 14 | 13 | 7

'ATN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S945. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
ATN1 MUTATED | 1 | 1 | 0 | 1
ATN1 WILD-TYPE | 16 | 7 | 14 | 15

'ATN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S946. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
ATN1 MUTATED | 1 | 1 | 0 | 1
ATN1 WILD-TYPE | 15 | 15 | 5 | 17

'ATN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S947. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
ATN1 MUTATED | 1 | 1 | 1
ATN1 WILD-TYPE | 25 | 11 | 17

'ATN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S948. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
ATN1 MUTATED | 1 | 2 | 0 | 0 | 0
ATN1 WILD-TYPE | 12 | 17 | 8 | 14 | 2

'ATN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S949. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
ATN1 MUTATED | 1 | 1 | 1
ATN1 WILD-TYPE | 26 | 12 | 15

'ATN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S950. Gene #135: 'ATN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
ATN1 MUTATED | 1 | 2 | 0 | 0 | 0 | 0
ATN1 WILD-TYPE | 8 | 15 | 7 | 12 | 6 | 5

'FAM46A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.897 (Fisher's exact test), Q value = 1

Table S951. Gene #136: 'FAM46A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
FAM46A MUTATED | 1 | 2 | 0 | 0 | 0
FAM46A WILD-TYPE | 20 | 17 | 8 | 8 | 6

'UTS2R MUTATION STATUS' versus 'CN_CNMF'

P value = 0.162 (Fisher's exact test), Q value = 1

Table S952. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
UTS2R MUTATED | 0 | 1 | 0 | 1 | 1
UTS2R WILD-TYPE | 21 | 18 | 8 | 7 | 5

'UTS2R MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.699 (Fisher's exact test), Q value = 1

Table S953. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
UTS2R MUTATED | 1 | 0 | 0 | 1 | 1
UTS2R WILD-TYPE | 12 | 8 | 14 | 13 | 6

'UTS2R MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.69 (Fisher's exact test), Q value = 1

Table S954. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
UTS2R MUTATED | 1 | 0 | 0 | 2
UTS2R WILD-TYPE | 16 | 8 | 14 | 14

'UTS2R MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S955. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
UTS2R MUTATED | 1 | 0 | 0 | 2
UTS2R WILD-TYPE | 15 | 16 | 5 | 16

'UTS2R MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S956. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
UTS2R MUTATED | 1 | 0 | 2
UTS2R WILD-TYPE | 25 | 12 | 16

'UTS2R MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S957. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
UTS2R MUTATED | 1 | 2 | 0 | 0 | 0
UTS2R WILD-TYPE | 12 | 17 | 8 | 14 | 2

'UTS2R MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S958. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
UTS2R MUTATED | 1 | 0 | 2
UTS2R WILD-TYPE | 26 | 13 | 14

'UTS2R MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S959. Gene #137: 'UTS2R MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
UTS2R MUTATED | 1 | 2 | 0 | 0 | 0 | 0
UTS2R WILD-TYPE | 8 | 15 | 7 | 12 | 6 | 5

'SMG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.164 (Fisher's exact test), Q value = 1

Table S960. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
SMG1 MUTATED | 0 | 1 | 1 | 0 | 1
SMG1 WILD-TYPE | 21 | 18 | 7 | 8 | 5

'SMG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S961. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
SMG1 MUTATED | 0 | 2 | 1 | 0 | 0
SMG1 WILD-TYPE | 13 | 6 | 13 | 14 | 7

'SMG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.143 (Fisher's exact test), Q value = 1

Table S962. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
SMG1 MUTATED | 0 | 1 | 2 | 0
SMG1 WILD-TYPE | 17 | 7 | 12 | 16

'SMG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0621 (Fisher's exact test), Q value = 1

Table S963. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
SMG1 MUTATED | 0 | 3 | 0 | 0
SMG1 WILD-TYPE | 16 | 13 | 5 | 18

'SMG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 1

Table S964. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
SMG1 MUTATED | 3 | 0 | 0
SMG1 WILD-TYPE | 23 | 12 | 18

'SMG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0256 (Fisher's exact test), Q value = 1

Table S965. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
SMG1 MUTATED | 1 | 0 | 1 | 0 | 1
SMG1 WILD-TYPE | 12 | 19 | 7 | 14 | 1

Figure S70. Get High-res Image Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'SMG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S966. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
SMG1 MUTATED | 3 | 0 | 0
SMG1 WILD-TYPE | 24 | 13 | 16

'SMG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.188 (Fisher's exact test), Q value = 1

Table S967. Gene #138: 'SMG1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
SMG1 MUTATED | 1 | 0 | 1 | 0 | 1 | 0
SMG1 WILD-TYPE | 8 | 17 | 6 | 12 | 5 | 5

'FUCA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.404 (Fisher's exact test), Q value = 1

Table S968. Gene #139: 'FUCA1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
FUCA1 MUTATED | 1 | 0 | 1 | 1 | 0
FUCA1 WILD-TYPE | 20 | 19 | 7 | 7 | 6

'FEZ2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S969. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
FEZ2 MUTATED | 0 | 2 | 1 | 0 | 0
FEZ2 WILD-TYPE | 21 | 17 | 7 | 8 | 6

'FEZ2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S970. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
FEZ2 MUTATED | 0 | 1 | 1 | 0 | 1
FEZ2 WILD-TYPE | 13 | 7 | 13 | 14 | 6

'FEZ2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.179 (Fisher's exact test), Q value = 1

Table S971. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
FEZ2 MUTATED | 0 | 1 | 0 | 2
FEZ2 WILD-TYPE | 17 | 7 | 14 | 14

'FEZ2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S972. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
FEZ2 MUTATED | 1 | 0 | 0 | 2
FEZ2 WILD-TYPE | 15 | 16 | 5 | 16

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 1

Table S973. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
FEZ2 MUTATED | 0 | 1 | 2
FEZ2 WILD-TYPE | 26 | 11 | 16

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.709 (Fisher's exact test), Q value = 1

Table S974. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
FEZ2 MUTATED | 0 | 1 | 1 | 1 | 0
FEZ2 WILD-TYPE | 13 | 18 | 7 | 13 | 2

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 1

Table S975. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
FEZ2 MUTATED | 0 | 1 | 2
FEZ2 WILD-TYPE | 27 | 12 | 14

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S976. Gene #140: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
FEZ2 MUTATED | 0 | 1 | 0 | 1 | 0 | 1
FEZ2 WILD-TYPE | 9 | 16 | 7 | 11 | 6 | 4

'GLI3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.737 (Fisher's exact test), Q value = 1

Table S977. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
GLI3 MUTATED | 3 | 1 | 0 | 1 | 0
GLI3 WILD-TYPE | 18 | 18 | 8 | 7 | 6

'GLI3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S978. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
GLI3 MUTATED | 2 | 0 | 0 | 1 | 1
GLI3 WILD-TYPE | 11 | 8 | 14 | 13 | 6

'GLI3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S979. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
GLI3 MUTATED | 2 | 0 | 1 | 1
GLI3 WILD-TYPE | 15 | 8 | 13 | 15

'GLI3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S980. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
GLI3 MUTATED | 2 | 1 | 0 | 1
GLI3 WILD-TYPE | 14 | 15 | 5 | 17

'GLI3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.134 (Fisher's exact test), Q value = 1

Table S981. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
GLI3 MUTATED | 4 | 0 | 0
GLI3 WILD-TYPE | 22 | 12 | 18

'GLI3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S982. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
GLI3 MUTATED | 1 | 0 | 1 | 2 | 0
GLI3 WILD-TYPE | 12 | 19 | 7 | 12 | 2

'GLI3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 1

Table S983. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
GLI3 MUTATED | 4 | 0 | 0
GLI3 WILD-TYPE | 23 | 13 | 16

'GLI3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0919 (Fisher's exact test), Q value = 1

Table S984. Gene #141: 'GLI3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
GLI3 MUTATED | 0 | 0 | 2 | 2 | 0 | 0
GLI3 WILD-TYPE | 9 | 17 | 5 | 10 | 6 | 5

'NOL9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00202 (Fisher's exact test), Q value = 1

Table S985. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 21 | 19 | 8 | 8 | 6
NOL9 MUTATED | 0 | 0 | 0 | 3 | 1
NOL9 WILD-TYPE | 21 | 19 | 8 | 5 | 5

Figure S71. Get High-res Image Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'NOL9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S986. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 8 | 14 | 14 | 7
NOL9 MUTATED | 1 | 0 | 1 | 1 | 0
NOL9 WILD-TYPE | 12 | 8 | 13 | 13 | 7

'NOL9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S987. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 17 | 8 | 14 | 16
NOL9 MUTATED | 1 | 0 | 1 | 1
NOL9 WILD-TYPE | 16 | 8 | 13 | 15

'NOL9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S988. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4
--- | --- | --- | --- | ---
ALL | 16 | 16 | 5 | 18
NOL9 MUTATED | 1 | 1 | 0 | 1
NOL9 WILD-TYPE | 15 | 15 | 5 | 17

'NOL9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.789 (Fisher's exact test), Q value = 1

Table S989. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 26 | 12 | 18
NOL9 MUTATED | 1 | 1 | 1
NOL9 WILD-TYPE | 25 | 11 | 17

'NOL9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.559 (Fisher's exact test), Q value = 1

Table S990. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5
--- | --- | --- | --- | --- | ---
ALL | 13 | 19 | 8 | 14 | 2
NOL9 MUTATED | 0 | 1 | 0 | 2 | 0
NOL9 WILD-TYPE | 13 | 18 | 8 | 12 | 2

'NOL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S991. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients | CLUS_1 | CLUS_2 | CLUS_3
--- | --- | --- | ---
ALL | 27 | 13 | 16
NOL9 MUTATED | 1 | 1 | 1
NOL9 WILD-TYPE | 26 | 12 | 15

'NOL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S992. Gene #142: 'NOL9 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6
--- | --- | --- | --- | --- | --- | ---
ALL | 9 | 17 | 7 | 12 | 6 | 5
NOL9 MUTATED | 0 | 1 | 0 | 2 | 0 | 0
NOL9 WILD-TYPE | 9 | 16 | 7 | 10 | 6 | 5

Methods & Data
Input

- Mutation data file = transformed.cor.cli.txt

- Molecular subtypes file = ACC-TP.transferedmergedcluster.txt

- Number of patients = 64

- Number of significantly mutated genes = 142

- Number of Molecular subtypes = 8

- Exclude genes that fewer than K tumors have mutations, K = 3

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

Download Results

In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.

- Analysis Results (MD5 checksum)

- Auxiliary Data (MD5 checksum)

- MAGE-TAB File (MD5 checksum)

References
[1] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)
[2] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)
Copyright © 2014 Broad Institute TCGA GDAC as part of the TCGA Research Network. All rights reserved.
Made with Nozzle