Clinical Features	Time to Death		AGE		NEOPLASM.DISEASESTAGE		PATHOLOGY.T.STAGE		PATHOLOGY.N.STAGE		GENDER		ETHNICITY	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
ZFPM1	23 (41%)	33	0.17489	1	0.43355	1	0.25563	1	0.94922	1	0.6834	1	0.77654	1	1	1
LACTB	17 (30%)	39	0.65076	1	0.6949	1	0.17622	1	0.076549	1	1	1	0.54348	1	0.64646	1
CCDC102A	16 (29%)	40	0.19333	1	0.30956	1	0.13797	1	0.24937	1	0.16145	1	1	1	0.63909	1
ZNF517	11 (20%)	45	0.6206	1	0.11687	1	0.7664	1	0.73626	1	1	1	0.732	1	0.5453	1
TOR3A	11 (20%)	45	0.57454	1	0.61321	1	0.19175	1	0.18162	1	0.5807	1	0.48076	1	1	1
USP42	13 (23%)	43	0.35488	1	0.28123	1	0.55351	1	0.81131	1	0.62739	1	1	1	1	1
CLDN23	10 (18%)	46	0.99192	1	0.81387	1	0.58825	1	0.65642	1	0.31515	1	0.46676	1	0.5453	1
TP53	11 (20%)	45	0.035607	1	0.62777	1	0.15932	1	0.40636	1	1	1	0.48076	1	0.57372	1
KCNK17	8 (14%)	48	0.29344	1	0.88822	1	0.89162	1	0.41646	1	0.58204	1	0.42279	1	0.1453	1
LZTR1	4 (7%)	52	0.15856	1	0.48378	1	0.87801	1	0.88231	1	0.39088	1	0.59806	1	1	1
APOE	5 (9%)	51	0.67558	1	0.13876	1	1	1	0.88251	1	1	1	0.32365	1	NA	NA
CCDC105	6 (11%)	50	0.49896	1	0.36053	1	0.43715	1	0.13031	1	0.53228	1	0.085688	1	1	1
RINL	7 (12%)	49	0.37279	1	0.76614	1	0.60222	1	0.53688	1	1	1	1	1	0.25299	1
MAL2	9 (16%)	47	0.34184	1	0.21545	1	0.77083	1	0.28864	1	0.26677	1	0.021232	1	0.28953	1
LRIG1	14 (25%)	42	0.56632	1	0.71202	1	0.72297	1	0.89832	1	0.14969	1	0.33775	1	0.63909	1
C19ORF10	6 (11%)	50	0.23594	1	0.19407	1	0.11112	1	0.41979	1	0.53228	1	0.65216	1	1	1
C10ORF95	6 (11%)	50	0.55871	1	0.84244	1	0.38176	1	1	1	1	1	1	1	0.55128	1
SYT8	5 (9%)	51	0.39364	1	0.53654	1	0.38199	1	1	1	1	1	0.65216	1	1	1
IDUA	8 (14%)	48	0.42352	1	0.15302	1	0.20672	1	0.50219	1	0.58204	1	1	1	0.55128	1
HHIPL1	6 (11%)	50	0.29084	1	0.33337	1	0.5756	1	0.68147	1	0.53228	1	0.39708	1	1	1
ASPDH	8 (14%)	48	0.80257	1	0.86054	1	0.0071399	1	0.5318	1	0.13139	1	0.70265	1	1	1
C1ORF106	8 (14%)	48	0.22214	1	0.50437	1	0.38888	1	0.24877	1	0.21946	1	0.24258	1	0.5453	1
THEM4	4 (7%)	52	0.34168	1	0.44493	1	0.45877	1	0.2992	1	0.30782	1	1	1	1	1
CTNNB1	6 (11%)	50	0.46796	1	0.080258	1	0.70959	1	0.92557	1	0.13139	1	0.085688	1	0.55128	1
GDF1	4 (7%)	52	0.13591	1	0.87355	1	0.33271	1	0.58539	1	1	1	0.59806	1	1	1
TSC22D2	8 (14%)	48	0.11471	1	0.50437	1	0.57298	1	0.30031	1	0.58204	1	0.70265	1	1	1
ZAR1	11 (20%)	45	0.52833	1	0.54275	1	0.53133	1	0.24752	1	0.59241	1	0.076919	1	0.5453	1
RGS9BP	7 (12%)	49	0.84907	1	0.66447	1	0.93577	1	0.03122	1	0.53228	1	0.6786	1	0.44444	1
OPRD1	11 (20%)	45	0.7669	1	0.26521	1	1	1	1	1	1	1	0.29921	1	1	1
C16ORF3	5 (9%)	51	0.32861	1	0.8293	1	0.5689	1	0.61544	1	0.46547	1	0.1547	1	1	1
FPGS	5 (9%)	51	0.78582	1	0.25617	1	0.56731	1	0.61843	1	0.46547	1	1	1	0.55128	1
PLIN5	5 (9%)	51	0.39007	1	0.5085	1	0.92022	1	1	1	0.46547	1	0.65216	1	0.44444	1
IRX3	4 (7%)	52	0.87384	1	0.16619	1	0.28094	1	0.45679	1	1	1	1	1	1	1
TRIOBP	10 (18%)	46	0.43097	1	0.85564	1	0.88111	1	1	1	0.073248	1	0.139	1	0.63909	1
KRTAP4-5	4 (7%)	52	0.18499	1	0.78674	1	0.53411	1	0.26101	1	1	1	1	1	1	1
ATXN1	9 (16%)	47	0.82187	1	0.29934	1	0.90838	1	0.50731	1	1	1	0.14588	1	1	1
ZNF628	6 (11%)	50	0.24073	1	0.40381	1	0.50971	1	0.39054	1	1	1	1	1	0.44444	1
WDR34	5 (9%)	51	0.49675	1	0.62506	1	1	1	0.88302	1	1	1	0.040588	1	1	1
BTBD11	5 (9%)	51	0.53877	1	0.63527	1	0.01078	1	0.12985	1	0.46547	1	0.65216	1	1	1
GARS	17 (30%)	39	0.10006	1	0.19618	1	0.01742	1	0.01613	1	0.65478	1	0.76328	1	0.63909	1
ZNF598	10 (18%)	46	0.30015	1	0.068872	1	0.54978	1	0.8928	1	0.57425	1	0.02229	1	0.25299	1
BHLHE22	5 (9%)	51	0.25879	1	0.85178	1	0.6546	1	1	1	0.092538	1	0.65216	1	0.25299	1
PTPLA	3 (5%)	53	0.69954	1	1	1	0.53285	1	0.48641	1	1	1	0.2632	1	0.44444	1
CD320	4 (7%)	52	0.95147	1	0.33166	1	0.22514	1	0.57382	1	1	1	1	1	0.1453	1
KIAA1984	3 (5%)	53	0.91889	1	0.30805	1	NA	NA	NA	NA	1	1	0.2632	1	0.44444	1
TPO	10 (18%)	46	0.41647	1	0.88936	1	0.79446	1	0.94587	1	0.073248	1	0.71982	1	1	1
AATK	5 (9%)	51	0.50238	1	0.077077	1	0.60817	1	0.68194	1	0.46547	1	0.65216	1	1	1
PANK2	4 (7%)	52	0.0021375	1	0.40792	1	0.87864	1	0.57599	1	1	1	0.10817	1	1	1
SNED1	6 (11%)	50	0.71556	1	0.77064	1	0.20766	1	0.26697	1	0.13139	1	0.65216	1	0.55128	1
CCDC150	4 (7%)	52	0.13495	1	0.50387	1	0.085689	1	0.1793	1	0.39088	1	1	1	0.1453	1
ERCC2	10 (18%)	46	0.59612	1	0.9488	1	0.68957	1	0.49221	1	0.31515	1	1	1	1	1
RREB1	4 (7%)	52	0.35361	1	0.87355	1	0.73037	1	0.17458	1	0.058636	1	0.59806	1	0.25	1
RNF39	5 (9%)	51	0.84194	1	0.73013	1	0.72996	1	0.88187	1	0.39088	1	1	1	0.44444	1
SEMA5B	6 (11%)	50	0.91483	1	0.62392	1	0.57473	1	0.68493	1	0.53228	1	0.16519	1	1	1
TAF5	3 (5%)	53	0.33257	1	0.92748	1	0.39435	1	0.80826	1	0.30782	1	0.54351	1	0.25	1
SARM1	6 (11%)	50	0.10131	1	0.93663	1	0.24222	1	0.19994	1	1	1	0.39708	1	0.1453	1
PRSS27	3 (5%)	53	0.13435	1	0.34388	1	0.61653	1	0.8089	1	1	1	0.2632	1	0.055556	1
TMEM189	3 (5%)	53	NA	NA	0.39227	1	NA	NA	NA	NA	1	1	1	1	0.44444	1
NOXA1	4 (7%)	52	0.80289	1	0.71434	1	0.87823	1	0.88413	1	0.39088	1	0.28798	1	1	1
LRP11	4 (7%)	52	0.15445	1	0.074681	1	0.84897	1	1	1	1	1	0.59806	1	1	1
RNF149	3 (5%)	53	0.22565	1	0.12627	1	0.27928	1	0.29949	1	1	1	0.54351	1	1	1
DMKN	3 (5%)	53	0.1628	1	0.32565	1	NA	NA	NA	NA	1	1	1	1	1	1
FANK1	3 (5%)	53	0.82181	1	0.35324	1	0.0082899	1	0.051429	1	0.30782	1	0.54351	1	0.55128	1
MUC5B	19 (34%)	37	0.99125	1	0.92414	1	0.86237	1	0.91931	1	0.65105	1	0.77239	1	0.67437	1
GLTPD2	6 (11%)	50	0.49446	1	0.073624	1	0.76905	1	0.83186	1	1	1	0.39708	1	0.25	1
MEN1	5 (9%)	51	0.11608	1	0.61492	1	0.085919	1	0.21714	1	0.39088	1	1	1	1	1
SRPX	3 (5%)	53	0.79185	1	0.88422	1	1	1	0.39031	1	0.30782	1	0.54351	1	1	1
MAP1S	5 (9%)	51	0.72441	1	0.35017	1	0.3815	1	0.68438	1	0.46547	1	0.32365	1	1	1
SCRT1	3 (5%)	53	0.03552	1	0.18393	1	1	1	0.8073	1	0.30782	1	0.54351	1	1	1
OBSCN	18 (32%)	38	0.64005	1	0.11826	1	0.31366	1	0.89303	1	0.075555	1	0.56038	1	1	1
IER5	3 (5%)	53	NA	NA	0.50064	1	0.13473	1	0.072289	1	0.30782	1	0.54351	1	1	1
TNIP2	5 (9%)	51	0.13426	1	0.66633	1	0.20031	1	0.66867	1	0.058636	1	1	1	0.55128	1
NOTCH2	5 (9%)	51	0.93659	1	0.87437	1	0.88059	1	0.88298	1	0.39088	1	1	1	1	1
RASIP1	7 (12%)	49	0.022493	1	1	1	0.57338	1	0.32142	1	1	1	0.40265	1	1	1
NMU	4 (7%)	52	0.13444	1	0.39013	1	1	1	0.88372	1	0.39088	1	0.28798	1	0.44444	1
VARS	6 (11%)	50	0.82148	1	0.92609	1	0.29249	1	0.36493	1	1	1	0.16519	1	0.037607	1
HSD17B1	4 (7%)	52	0.6568	1	0.5244	1	0.32235	1	0.45751	1	1	1	1	1	0.44444	1
COQ2	4 (7%)	52	0.62816	1	0.33964	1	0.41724	1	0.66749	1	1	1	1	1	NA	NA
KNDC1	9 (16%)	47	0.62781	1	0.98219	1	0.1356	1	0.19623	1	1	1	0.14588	1	0.55128	1
AR	4 (7%)	52	0.1053	1	0.71434	1	0.72848	1	0.21525	1	0.39088	1	1	1	1	1
KCTD3	3 (5%)	53	NA	NA	0.536	1	NA	NA	NA	NA	1	1	1	1	1	1
KRTAP5-5	3 (5%)	53	0.0016393	1	0.40242	1	0.39406	1	0.80919	1	1	1	1	1	1	1
AKAP2	4 (7%)	52	0.87384	1	0.54535	1	0.36793	1	0.88188	1	1	1	0.10817	1	NA	NA
KBTBD13	9 (16%)	47	0.42302	1	0.56926	1	0.16498	1	0.13189	1	0.26677	1	0.14588	1	1	1
SPIRE2	3 (5%)	53	0.87142	1	0.080565	1	0.53345	1	0.22337	1	1	1	0.54351	1	0.25	1
NPTX1	3 (5%)	53	0.96067	1	0.8271	1	0.4593	1	0.48604	1	1	1	0.2632	1	1	1
ADAD2	3 (5%)	53	0.84835	1	0.94196	1	NA	NA	NA	NA	1	1	0.2632	1	NA	NA
SEZ6L2	5 (9%)	51	0.81528	1	0.53654	1	0.13961	1	0.24868	1	0.46547	1	0.65216	1	0.55128	1
NEFH	5 (9%)	51	0.00023584	0.2	0.30749	1	0.65209	1	0.20045	1	0.46547	1	1	1	0.1453	1
AMDHD1	10 (18%)	46	0.93459	1	0.023945	1	0.69406	1	0.94636	1	0.57425	1	0.28135	1	1	1
GLTSCR2	4 (7%)	52	0.6436	1	0.20867	1	1	1	1	1	0.39088	1	0.10817	1	1	1
PLEC	10 (18%)	46	0.33212	1	0.38604	1	0.45102	1	0.58495	1	1	1	0.139	1	1	1
MAP7	3 (5%)	53	0.91027	1	0.78483	1	0.85096	1	1	1	1	1	1	1	1	1
DSPP	9 (16%)	47	0.79317	1	0.33719	1	0.95207	1	0.94502	1	0.26677	1	0.70265	1	0.63909	1
CRIPAK	8 (14%)	48	0.90514	1	0.32518	1	0.10078	1	0.29922	1	0.57425	1	0.70265	1	1	1
PRKAR1A	6 (11%)	50	0.63268	1	0.92609	1	0.20611	1	0.15311	1	0.53228	1	0.085688	1	0.44444	1
CYP4A22	3 (5%)	53	0.057543	1	0.44457	1	0.39206	1	0.80585	1	1	1	1	1	0.44444	1
NOM1	5 (9%)	51	0.65739	1	0.8293	1	0.16663	1	0.22203	1	1	1	1	1	1	1
C12ORF65	3 (5%)	53	0.0006842	0.58	0.25149	1	0.13499	1	0.070089	1	0.30782	1	0.54351	1	1	1
HLA-B	6 (11%)	50	0.10953	1	0.94717	1	0.92023	1	1	1	0.46547	1	0.16519	1	1	1
CSGALNACT2	3 (5%)	53	0.74644	1	0.79885	1	0.72563	1	1	1	1	1	0.54351	1	1	1
UQCRFS1	5 (9%)	51	0.29597	1	0.054103	1	0.097909	1	0.04735	1	0.46547	1	1	1	0.25299	1
PDCD6	3 (5%)	53	0.96255	1	0.10138	1	0.0086199	1	0.0067599	1	0.30782	1	1	1	0.25	1
PTX4	3 (5%)	53	0.00023884	0.203	0.26685	1	0.02632	1	0.072459	1	1	1	1	1	1	1
POLRMT	4 (7%)	52	0.15575	1	0.9113	1	0.25194	1	0.34981	1	1	1	0.59806	1	NA	NA
NF1	7 (12%)	49	0.28567	1	0.62886	1	0.65839	1	0.801	1	1	1	0.0045459	1	1	1
ADAMTS7	4 (7%)	52	0.16841	1	0.10117	1	0.25372	1	0.35131	1	1	1	1	1	1	1
CLIC6	4 (7%)	52	0.42979	1	0.69073	1	0.42062	1	0.6668	1	1	1	0.28798	1	1	1
EMR2	4 (7%)	52	0.85314	1	0.037088	1	0.72256	1	1	1	1	1	0.10817	1	1	1
PCDHB13	4 (7%)	52	0.66675	1	0.034292	1	0.19908	1	0.095869	1	1	1	0.59806	1	0.055556	1
HLA-A	3 (5%)	53	0.31521	1	0.24404	1	0.85086	1	0.39171	1	1	1	0.2632	1	0.25	1
ASB16	4 (7%)	52	0.61206	1	0.4355	1	1	1	0.8833	1	1	1	1	1	NA	NA
GPRIN2	7 (12%)	49	0.98817	1	0.64656	1	0.79468	1	0.68428	1	0.58204	1	1	1	1	1
HNRNPCL1	3 (5%)	53	NA	NA	0.64907	1	1	1	0.80973	1	1	1	1	1	1	1
BTNL9	3 (5%)	53	0.7551	1	0.75699	1	NA	NA	NA	NA	1	1	1	1	1	1
KCNJ11	4 (7%)	52	0.49633	1	0.4739	1	0.085129	1	0.88187	1	0.058636	1	0.59806	1	1	1
LRRC4B	6 (11%)	50	0.26336	1	0.70076	1	0.38974	1	1	1	0.13139	1	0.65216	1	0.5453	1
OPLAH	3 (5%)	53	0.17361	1	0.30805	1	0.17827	1	0.14758	1	1	1	1	1	1	1
MADCAM1	3 (5%)	53	0.5135	1	0.43381	1	0.1786	1	0.14513	1	0.30782	1	0.54351	1	0.44444	1
MSH3	3 (5%)	53	0.041213	1	0.6231	1	0.072869	1	0.14761	1	1	1	0.54351	1	1	1
UTS2R	3 (5%)	53	0.45278	1	0.32565	1	0.33715	1	0.58439	1	1	1	1	1	1	1
SMG1	3 (5%)	53	0.76698	1	0.77087	1	0.13593	1	0.80684	1	0.30782	1	1	1	0.55128	1
FEZ2	3 (5%)	53	0.72202	1	0.44457	1	0.72236	1	0.58203	1	0.30782	1	1	1	0.55128	1
GLI3	5 (9%)	51	0.28802	1	0.91986	1	0.04159	1	0.02326	1	1	1	0.65216	1	1	1
NOL9	3 (5%)	53	0.87822	1	0.060816	1	NA	NA	NA	NA	1	1	0.2632	1	NA	NA