Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 57 (22%) 207 0.03061 1 0.01426 1 0.69147 1 0.61314 1 0.79533 1 0.99612 1 0.69607 1 0.85667 1 0.95953 1 0.84299 1 1q gain 83 (31%) 181 0.00084999 0.649 0.2509 1 0.59952 1 0.88492 1 0.77475 1 0.9514 1 0.76262 1 0.9772 1 0.70178 1 0.81839 1 2p gain 75 (28%) 189 0.00018 0.14 9.9999e-06 0.008 0.32641 1 0.73537 1 0.10744 1 0.062979 1 0.1366 1 0.03561 1 0.1992 1 0.03668 1 2q gain 37 (14%) 227 0.096529 1 0.16703 1 0.30759 1 0.35161 1 0.428 1 0.55354 1 0.5023 1 0.41589 1 0.72758 1 0.31184 1 3p gain 92 (35%) 172 0.00214 1 0.22855 1 0.098109 1 0.40494 1 0.0075299 1 0.01838 1 0.0031 1 0.0094299 1 0.00168 1 0.00105 0.801 3q gain 118 (45%) 146 5e-05 0.0393 0.36276 1 0.5678 1 1 1 0.39873 1 0.19703 1 0.0091799 1 0.00056999 0.438 0.00128 0.975 0.00044 0.34 4p gain 33 (12%) 231 0.00072999 0.56 0.01334 1 0.60785 1 0.41372 1 0.034 1 0.0057699 1 0.13474 1 0.00183 1 0.054829 1 0.00471 1 4q gain 19 (7%) 245 0.0050699 1 0.02649 1 0.54391 1 0.20304 1 0.03761 1 0.089979 1 0.26758 1 0.13224 1 0.32464 1 0.40934 1 5p gain 103 (39%) 161 0.00283 1 0.17657 1 0.04292 1 0.24014 1 0.32599 1 0.12277 1 0.070179 1 0.03605 1 0.34589 1 0.10618 1 5q gain 37 (14%) 227 0.36763 1 0.04012 1 0.02403 1 0.28277 1 0.78592 1 0.73802 1 0.26076 1 0.14427 1 0.11959 1 0.50283 1 6p gain 43 (16%) 221 0.46474 1 0.74315 1 0.84726 1 0.13289 1 0.43583 1 0.30538 1 0.54461 1 0.75045 1 0.56031 1 0.83261 1 6q gain 24 (9%) 240 0.36939 1 0.81629 1 0.97496 1 0.04161 1 0.30578 1 0.054469 1 0.28684 1 0.40867 1 0.20779 1 0.74091 1 7p gain 111 (42%) 153 0.00024 0.186 0.10203 1 0.02114 1 0.44523 1 0.92327 1 0.7949 1 0.26302 1 0.33277 1 0.55499 1 0.27892 1 7q gain 101 (38%) 163 0.00237 1 0.33139 1 0.19441 1 0.92124 1 0.82469 1 0.31003 1 0.33106 1 0.46148 1 0.39591 1 0.11802 1 8p gain 55 (21%) 209 8.9999e-05 0.0704 0.058449 1 0.083309 1 0.01844 1 0.52263 1 0.99619 1 0.26017 1 0.01781 1 0.14006 1 0.16102 1 8q gain 122 (46%) 142 0.00017 0.133 0.01499 1 0.03972 1 0.18644 1 0.35508 1 0.84047 1 0.35276 1 0.01175 1 0.10857 1 0.14539 1 9p gain 40 (15%) 224 0.00044 0.34 0.66047 1 0.8596 1 0.3811 1 0.188 1 0.10027 1 0.33726 1 0.12882 1 0.74478 1 0.29708 1 9q gain 36 (14%) 228 0.01654 1 0.1723 1 0.88095 1 0.02928 1 0.0064999 1 0.00075999 0.581 0.97369 1 0.37055 1 0.86471 1 0.04958 1 10p gain 75 (28%) 189 5.9999e-05 0.0471 0.00414 1 0.8371 1 0.43109 1 0.67049 1 0.083019 1 0.63832 1 0.78579 1 0.77542 1 0.9823 1 10q gain 23 (9%) 241 0.04398 1 0.092439 1 0.55955 1 0.54901 1 0.52557 1 0.01168 1 0.78748 1 0.68979 1 0.77267 1 0.46436 1 11p gain 25 (9%) 239 0.42826 1 0.082899 1 0.11384 1 0.12185 1 0.083959 1 0.059379 1 0.48932 1 0.0138 1 0.57514 1 0.081499 1 11q gain 37 (14%) 227 0.57738 1 0.42894 1 0.19951 1 0.04724 1 0.17786 1 0.0214 1 0.63349 1 0.10447 1 0.75305 1 0.15839 1 12p gain 75 (28%) 189 0.069719 1 0.19791 1 0.75808 1 0.5305 1 0.73891 1 0.9531 1 0.85387 1 0.13782 1 0.72504 1 0.39637 1 12q gain 56 (21%) 208 0.00407 1 0.0088299 1 0.068079 1 0.01288 1 0.11377 1 0.064999 1 0.51729 1 0.38367 1 0.36627 1 0.15337 1 13q gain 70 (27%) 194 0.23974 1 0.89464 1 0.97582 1 0.83944 1 0.24032 1 0.42356 1 0.75456 1 0.39552 1 0.80816 1 0.83287 1 14q gain 44 (17%) 220 0.15319 1 0.33718 1 0.37847 1 0.1496 1 0.03853 1 0.23437 1 1 1 0.04222 1 0.53116 1 0.92323 1 15q gain 24 (9%) 240 0.0072599 1 0.076499 1 0.71528 1 0.80378 1 0.65524 1 0.22967 1 0.30763 1 0.75434 1 1 1 0.84362 1 16p gain 42 (16%) 222 0.16579 1 0.80364 1 0.37424 1 0.34124 1 0.63494 1 0.46735 1 0.22158 1 0.4181 1 0.47426 1 0.85039 1 16q gain 52 (20%) 212 0.27125 1 0.6267 1 0.13474 1 0.13996 1 0.38058 1 0.13507 1 0.10198 1 0.087539 1 0.18971 1 0.54396 1 17p gain 35 (13%) 229 0.086909 1 0.39797 1 0.55001 1 0.875 1 0.73482 1 0.0414 1 0.00269 1 0.01382 1 0.00134 1 0.00341 1 17q gain 90 (34%) 174 2e-04 0.156 0.24927 1 0.49683 1 0.38765 1 0.14891 1 0.21962 1 0.11146 1 0.0028 1 0.00346 1 0.00458 1 18p gain 79 (30%) 185 0.02608 1 0.00303 1 0.95091 1 0.91161 1 0.19002 1 0.03901 1 0.66667 1 0.10205 1 0.74604 1 0.98262 1 18q gain 41 (16%) 223 0.40866 1 0.072279 1 0.3208 1 0.30215 1 0.67685 1 0.41766 1 0.52531 1 0.21811 1 0.5344 1 0.41369 1 19p gain 55 (21%) 209 0.0095799 1 0.04211 1 0.26702 1 0.42079 1 0.01769 1 0.099059 1 0.74589 1 0.03368 1 0.50171 1 0.061049 1 19q gain 90 (34%) 174 9.9999e-05 0.0781 0.0023 1 0.31954 1 0.54913 1 0.26726 1 0.25369 1 0.80576 1 0.0272 1 0.66915 1 0.064659 1 20p gain 131 (50%) 133 0.33062 1 0.43725 1 0.53927 1 0.04985 1 0.69431 1 0.02691 1 0.16844 1 0.04623 1 0.03911 1 0.17679 1 20q gain 147 (56%) 117 0.0089199 1 0.21336 1 0.39969 1 0.11707 1 0.9615 1 0.61505 1 0.14437 1 0.01294 1 0.16864 1 0.13408 1 21q gain 79 (30%) 185 9.9999e-06 0.008 6.9999e-05 0.0549 0.65313 1 0.40278 1 0.04726 1 0.00478 1 0.00214 1 0.0070099 1 0.0066499 1 0.00247 1 22q gain 36 (14%) 228 0.00298 1 0.0065999 1 0.41793 1 0.33681 1 0.0183 1 0.20813 1 0.19478 1 0.2024 1 0.40541 1 0.43768 1 xq gain 33 (12%) 231 0.01317 1 0.36614 1 0.70696 1 0.57411 1 0.91634 1 0.92232 1 0.52306 1 0.6688 1 0.42694 1 0.33786 1 1p loss 23 (9%) 241 0.34036 1 0.3047 1 0.10815 1 0.080989 1 0.52619 1 0.11134 1 0.64079 1 0.19551 1 0.88035 1 0.95914 1 1q loss 25 (9%) 239 0.72072 1 0.59761 1 0.40401 1 0.95622 1 0.43523 1 0.13201 1 0.52707 1 0.00247 1 1 1 0.77979 1 2p loss 27 (10%) 237 0.42392 1 0.10518 1 0.96082 1 0.7522 1 0.73185 1 0.25909 1 0.17876 1 0.93985 1 0.66484 1 0.29629 1 2q loss 58 (22%) 206 0.095429 1 0.35395 1 0.7479 1 0.54223 1 0.29248 1 0.14836 1 0.69897 1 0.04972 1 0.33221 1 0.097109 1 3p loss 31 (12%) 233 0.83205 1 0.04129 1 0.02226 1 0.02484 1 9.9999e-06 0.008 9.9999e-06 0.008 0.40333 1 0.13035 1 0.16475 1 0.10267 1 3q loss 13 (5%) 251 0.93504 1 0.17282 1 0.01888 1 0.052229 1 0.10007 1 0.01059 1 1 1 0.62114 1 1 1 0.74647 1 4p loss 86 (33%) 178 0.76317 1 0.8085 1 0.7425 1 0.78034 1 0.16108 1 0.02702 1 0.053979 1 0.48054 1 0.14582 1 0.071239 1 4q loss 91 (34%) 173 0.54548 1 0.37965 1 0.30368 1 0.34767 1 0.23814 1 0.12665 1 0.17006 1 0.47584 1 0.15826 1 0.076319 1 5p loss 40 (15%) 224 0.01738 1 0.01901 1 0.31605 1 0.66545 1 0.63422 1 0.04792 1 0.57636 1 0.90533 1 0.40403 1 1 1 5q loss 104 (39%) 160 0.00229 1 0.0055499 1 0.86048 1 0.34576 1 0.51724 1 0.078659 1 0.75004 1 0.1482 1 0.73773 1 0.17341 1 6p loss 64 (24%) 200 0.00229 1 0.01889 1 0.75454 1 0.82453 1 0.060629 1 0.01117 1 0.65452 1 0.00024 0.186 0.61557 1 0.01725 1 6q loss 97 (37%) 167 9.9999e-06 0.008 0.00465 1 0.83323 1 0.49099 1 0.22946 1 0.01297 1 0.80034 1 0.01248 1 0.942 1 0.2185 1 7p loss 11 (4%) 253 0.25676 1 0.97318 1 0.32224 1 0.86052 1 0.73996 1 0.71874 1 0.24987 1 0.11196 1 0.083219 1 0.19248 1 7q loss 16 (6%) 248 0.086219 1 0.76254 1 0.23109 1 0.67702 1 0.60974 1 1 1 0.25193 1 0.082509 1 0.69769 1 0.94225 1 8p loss 121 (46%) 143 5e-05 0.0393 0.00072999 0.56 0.21631 1 0.16989 1 0.051329 1 0.6104 1 0.01801 1 0.03062 1 0.04491 1 0.0421 1 8q loss 29 (11%) 235 0.23687 1 0.096299 1 0.49832 1 0.01071 1 0.00307 1 0.16887 1 0.03471 1 0.04363 1 0.00299 1 0.1371 1 9p loss 114 (43%) 150 9.9999e-06 0.008 0.1751 1 0.19255 1 0.060839 1 0.41881 1 0.00276 1 0.67106 1 0.34769 1 0.95832 1 1 1 9q loss 104 (39%) 160 9.9999e-06 0.008 0.01187 1 0.02789 1 0.0098999 1 0.0284 1 6.9999e-05 0.0549 0.97254 1 0.13671 1 0.56927 1 0.28538 1 10p loss 47 (18%) 217 0.50298 1 0.01299 1 0.91111 1 0.2645 1 0.0242 1 0.062699 1 0.31514 1 0.29276 1 0.56842 1 0.30504 1 10q loss 87 (33%) 177 0.00065999 0.507 0.0091399 1 0.56321 1 0.7298 1 0.04246 1 0.2926 1 0.2988 1 0.13341 1 0.26232 1 0.42034 1 11p loss 108 (41%) 156 9.9999e-06 0.008 9.9999e-06 0.008 0.18008 1 0.7481 1 0.00202 1 5e-04 0.385 0.11579 1 0.093879 1 0.0057399 1 0.074929 1 11q loss 81 (31%) 183 9.9999e-06 0.008 0.00132 1 0.057289 1 0.19867 1 0.0259 1 0.067949 1 0.51616 1 0.61048 1 0.081699 1 0.31703 1 12p loss 28 (11%) 236 0.22696 1 0.46178 1 0.94324 1 0.4723 1 0.39854 1 0.64566 1 0.37396 1 0.90308 1 0.69915 1 0.89192 1 12q loss 34 (13%) 230 0.58688 1 0.72793 1 0.3688 1 0.40853 1 0.97336 1 0.89132 1 0.48565 1 0.74069 1 0.91351 1 0.93794 1 13q loss 53 (20%) 211 0.00351 1 0.87202 1 0.01064 1 0.10277 1 0.094279 1 0.60876 1 1 1 0.01077 1 0.86054 1 0.25124 1 14q loss 75 (28%) 189 9.9999e-06 0.008 0.00039 0.301 0.070009 1 0.03751 1 0.055139 1 0.00037 0.286 0.01185 1 0.01409 1 0.02907 1 0.39595 1 15q loss 88 (33%) 176 0.0058799 1 0.00026 0.201 0.10722 1 0.31706 1 0.45168 1 0.070639 1 0.15245 1 4e-05 0.0315 0.092659 1 0.31077 1 16p loss 68 (26%) 196 0.069379 1 0.04408 1 0.65728 1 0.47684 1 0.6341 1 0.77807 1 0.77442 1 0.050679 1 0.70974 1 0.49947 1 16q loss 62 (23%) 202 0.02766 1 0.03646 1 0.22557 1 0.79204 1 0.56338 1 0.79902 1 0.3418 1 0.054349 1 0.57462 1 0.079469 1 17p loss 116 (44%) 148 9.9999e-06 0.008 0.41219 1 0.95689 1 0.72851 1 0.40779 1 0.096989 1 0.2644 1 0.096259 1 0.16415 1 0.45279 1 17q loss 27 (10%) 237 0.25796 1 0.27 1 0.97031 1 0.94193 1 0.86928 1 0.86398 1 0.8111 1 0.57104 1 0.8928 1 0.8257 1 18p loss 60 (23%) 204 0.01837 1 0.26464 1 0.46409 1 0.3719 1 0.65164 1 0.04095 1 0.59544 1 0.24035 1 0.58958 1 0.70795 1 18q loss 91 (34%) 173 0.04768 1 0.99529 1 0.68271 1 0.74317 1 0.89122 1 0.33835 1 0.0358 1 0.0092999 1 0.11637 1 0.11998 1 19p loss 67 (25%) 197 0.01163 1 0.19634 1 0.59611 1 0.39806 1 0.01425 1 0.17773 1 0.82808 1 0.03411 1 0.64315 1 0.28982 1 19q loss 41 (16%) 223 0.22132 1 0.61808 1 0.20523 1 0.096759 1 0.33533 1 0.67502 1 0.42156 1 0.52608 1 0.35709 1 0.23839 1 20p loss 23 (9%) 241 0.10061 1 0.03247 1 0.16518 1 0.03282 1 0.75714 1 0.46131 1 0.39362 1 0.84445 1 0.16732 1 0.79708 1 20q loss 9 (3%) 255 0.02778 1 0.44353 1 0.47878 1 0.34587 1 1 1 0.87275 1 0.63148 1 0.81707 1 1 1 0.52732 1 21q loss 44 (17%) 220 0.20425 1 0.01967 1 0.10571 1 0.29551 1 0.01958 1 0.02463 1 0.77031 1 0.39847 1 0.19444 1 0.48522 1 22q loss 102 (39%) 162 0.01458 1 0.01713 1 0.58118 1 0.01156 1 0.02941 1 0.17673 1 0.22181 1 0.03035 1 0.097629 1 0.088089 1 xq loss 50 (19%) 214 0.03137 1 0.00403 1 0.99476 1 0.71394 1 0.12453 1 0.76296 1 0.02846 1 0.85455 1 0.089619 1 0.398 1