Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q amp_1p34.2 70 (27%) 194 9.9999e-06 0.007 0.00164 0.999 0.17799 1 0.3808 1 0.79217 1 0.4327 1 0.14803 1 0.30161 1 0.82185 1 0.92907 1 amp_1q21.3 128 (48%) 136 9.9999e-06 0.007 2e-05 0.0132 0.39117 1 0.72182 1 0.02523 1 0.03832 1 0.04417 1 0.00376 1 0.33547 1 0.12494 1 amp_1q23.3 135 (51%) 129 9.9999e-06 0.007 0.00162 0.988 0.55099 1 0.88627 1 0.12314 1 0.30857 1 0.00309 1 0.01438 1 0.0414 1 0.04955 1 amp_3p25.2 127 (48%) 137 9.9999e-06 0.007 4e-05 0.0261 0.078949 1 0.01035 1 9.9999e-06 0.007 2e-05 0.0132 6.9999e-05 0.0454 2e-05 0.0132 9.9999e-06 0.007 7.9999e-05 0.0518 amp_3q26.32 142 (54%) 122 9.9999e-06 0.007 0.56991 1 0.3892 1 0.15424 1 0.73857 1 0.36805 1 0.57465 1 0.0065299 1 0.41707 1 0.090859 1 amp_4p16.3 53 (20%) 211 0.00245 1 0.04893 1 0.03289 1 0.02675 1 0.0078699 1 0.00067999 0.423 0.02052 1 0.0050399 1 0.0080399 1 0.01743 1 amp_4q13.3 49 (19%) 215 0.00049 0.308 0.0080699 1 0.58087 1 0.70537 1 0.37131 1 0.3167 1 0.42814 1 0.077899 1 0.073529 1 0.071279 1 amp_4q31.21 29 (11%) 235 0.18196 1 0.20092 1 0.1233 1 0.26272 1 0.29277 1 0.17958 1 0.23632 1 0.065289 1 0.84222 1 0.33176 1 amp_5p15.33 131 (50%) 133 9.9999e-06 0.007 0.04062 1 0.02093 1 0.17973 1 0.46923 1 0.23276 1 0.0090999 1 0.00022 0.141 0.21483 1 0.00429 1 amp_6p22.3 111 (42%) 153 9.9999e-06 0.007 0.0014 0.857 0.32117 1 0.48654 1 0.73714 1 0.80681 1 0.29368 1 0.17559 1 0.35447 1 0.12462 1 amp_6q21 23 (9%) 241 0.04177 1 0.091779 1 0.51488 1 0.078879 1 0.48392 1 0.60533 1 0.78881 1 0.22936 1 0.74008 1 0.83606 1 amp_7p21.1 134 (51%) 130 0.00014 0.0902 0.01314 1 0.13255 1 0.32016 1 0.88788 1 0.87968 1 0.19318 1 0.083879 1 0.72809 1 0.4702 1 amp_7p11.2 131 (50%) 133 9.9999e-06 0.007 0.0148 1 0.089699 1 0.59974 1 0.98718 1 0.51581 1 0.4044 1 0.23988 1 0.64153 1 0.54317 1 amp_8p11.23 84 (32%) 180 9.9999e-06 0.007 0.096959 1 0.7458 1 0.79102 1 1 1 0.74973 1 0.24431 1 0.54427 1 0.067889 1 0.41141 1 amp_8p11.21 86 (33%) 178 9.9999e-06 0.007 0.0274 1 0.88829 1 0.94924 1 0.52196 1 0.39897 1 0.03205 1 0.00147 0.898 0.02083 1 0.01891 1 amp_8q22.3 169 (64%) 95 9.9999e-06 0.007 0.00074999 0.465 0.02433 1 0.19279 1 0.61205 1 0.62928 1 0.080249 1 0.00063999 0.399 0.01792 1 0.11381 1 amp_9p24.1 53 (20%) 211 9.9999e-06 0.007 0.28403 1 0.67129 1 0.32592 1 0.32987 1 0.079509 1 0.94206 1 0.03888 1 0.82552 1 0.27558 1 amp_10p14 116 (44%) 148 9.9999e-06 0.007 9.9999e-06 0.007 0.35742 1 0.42614 1 0.51515 1 0.10967 1 0.43308 1 0.16169 1 0.38784 1 0.22965 1 amp_11q13.3 101 (38%) 163 7.9999e-05 0.0518 0.32276 1 0.2343 1 0.079429 1 0.18328 1 0.15279 1 0.16995 1 0.00423 1 0.65337 1 0.71628 1 amp_11q22.2 49 (19%) 215 0.15145 1 0.1288 1 0.73145 1 0.41342 1 0.067649 1 0.01448 1 0.096019 1 0.00133 0.815 0.15985 1 0.16098 1 amp_12q15 77 (29%) 187 0.0070299 1 0.13224 1 0.03847 1 0.01982 1 0.022 1 0.02151 1 0.18779 1 0.0174 1 0.03567 1 0.0083299 1 amp_13q22.1 84 (32%) 180 0.29128 1 0.75018 1 0.96171 1 0.85037 1 0.88643 1 0.95442 1 0.75214 1 0.68335 1 0.57537 1 0.33485 1 amp_14q11.2 63 (24%) 201 0.74221 1 0.42207 1 0.61396 1 0.090279 1 0.35499 1 0.31655 1 0.48973 1 0.00029 0.184 0.57334 1 1 1 amp_16p13.13 56 (21%) 208 0.00039 0.246 0.25315 1 0.52001 1 0.67301 1 0.35011 1 0.78167 1 0.61658 1 0.28597 1 0.50449 1 0.41397 1 amp_16p11.2 64 (24%) 200 0.01009 1 0.25102 1 0.46906 1 0.36812 1 0.78233 1 0.71165 1 0.86738 1 0.65606 1 0.75479 1 0.96152 1 amp_16q22.1 75 (28%) 189 0.065069 1 0.85869 1 0.084299 1 0.086139 1 0.069539 1 0.055489 1 0.41345 1 0.19119 1 0.28896 1 0.49965 1 amp_17q11.2 117 (44%) 147 9.9999e-06 0.007 0.00022 0.141 0.03212 1 0.088549 1 0.00039 0.246 0.00305 1 0.059159 1 0.00070999 0.441 0.00187 1 0.01008 1 amp_17q12 110 (42%) 154 9.9999e-06 0.007 0.16331 1 0.077919 1 0.01869 1 0.0051099 1 0.01534 1 0.00363 1 0.00177 1 0.00017 0.109 0.00112 0.689 amp_19q12 109 (41%) 155 9.9999e-06 0.007 0.00021 0.135 0.70337 1 0.54649 1 0.058239 1 0.15945 1 0.35564 1 0.00111 0.684 0.33406 1 0.04543 1 amp_19q13.43 103 (39%) 161 9.9999e-06 0.007 0.0090799 1 0.16723 1 0.30171 1 0.30513 1 0.94534 1 0.67151 1 0.03524 1 0.25977 1 0.03667 1 amp_20q11.21 171 (65%) 93 3e-04 0.19 0.04586 1 0.71273 1 0.055419 1 0.94376 1 0.32041 1 0.48799 1 0.00195 1 0.32985 1 0.5753 1 amp_22q11.23 55 (21%) 209 0.00057999 0.364 0.03632 1 0.59177 1 0.60956 1 0.02793 1 0.10273 1 0.16172 1 0.23539 1 0.4335 1 0.51918 1 del_1p36.11 52 (20%) 212 0.45979 1 0.17734 1 0.2511 1 0.0303 1 0.18944 1 0.60302 1 0.81364 1 0.32946 1 0.51978 1 0.34351 1 del_1q32.1 47 (18%) 217 0.097279 1 0.14189 1 0.35298 1 0.60137 1 0.43002 1 0.10743 1 0.1571 1 0.01016 1 0.097259 1 0.33867 1 del_2q22.1 80 (30%) 184 0.00331 1 0.089639 1 0.27064 1 0.94252 1 0.13681 1 0.15248 1 0.30914 1 0.25438 1 0.13756 1 0.38814 1 del_2q37.1 130 (49%) 134 9.9999e-06 0.007 0.0117 1 0.59313 1 0.44326 1 0.3067 1 0.122 1 0.068479 1 0.076189 1 0.084059 1 0.063559 1 del_3p21.31 77 (29%) 187 0.03576 1 0.38279 1 0.03012 1 0.0073299 1 9.9999e-06 0.007 4e-05 0.0261 0.10575 1 0.01948 1 0.13393 1 0.062619 1 del_3p14.2 75 (28%) 189 0.057769 1 0.49904 1 0.03373 1 0.01723 1 2e-05 0.0132 2e-05 0.0132 0.35069 1 0.00261 1 0.088929 1 0.04052 1 del_3p13 71 (27%) 193 0.38607 1 0.36583 1 0.1196 1 0.0023 1 2e-05 0.0132 0.00011 0.0709 0.53563 1 0.04099 1 0.17199 1 0.01712 1 del_4q22.1 109 (41%) 155 0.27333 1 0.25792 1 0.50697 1 0.50167 1 0.091889 1 0.068499 1 0.30389 1 0.14003 1 0.085489 1 0.0344 1 del_4q34.2 119 (45%) 145 0.01272 1 0.3381 1 0.45765 1 0.79513 1 0.73154 1 0.48843 1 0.053219 1 0.14638 1 0.18597 1 0.078969 1 del_5q11.2 133 (50%) 131 9.9999e-06 0.007 0.00091999 0.569 0.9575 1 0.62462 1 0.57783 1 0.077879 1 0.17201 1 0.00279 1 0.6089 1 0.14194 1 del_5q35.1 126 (48%) 138 3e-05 0.0197 0.00017 0.109 0.47186 1 0.32986 1 0.42847 1 0.059069 1 0.39342 1 0.0087199 1 0.50715 1 0.04811 1 del_6p25.3 69 (26%) 195 0.01653 1 0.03402 1 0.83866 1 0.87194 1 0.42455 1 0.074439 1 0.6044 1 0.27446 1 0.94802 1 0.54386 1 del_6q21 117 (44%) 147 9.9999e-06 0.007 0.02546 1 0.85456 1 0.43172 1 0.64491 1 0.069049 1 0.32599 1 0.00472 1 0.4154 1 0.10108 1 del_6q27 119 (45%) 145 9.9999e-06 0.007 0.01645 1 0.66075 1 0.43519 1 0.24081 1 0.01099 1 0.080519 1 3e-05 0.0197 0.16631 1 0.066939 1 del_7q36.3 39 (15%) 225 0.44934 1 0.054509 1 0.20577 1 0.23779 1 0.29111 1 0.40404 1 0.71698 1 0.01558 1 1 1 0.89435 1 del_8p23.3 151 (57%) 113 9.9999e-06 0.007 9.9999e-06 0.007 0.55268 1 0.19411 1 0.18169 1 0.85748 1 0.00239 1 0.01253 1 0.0381 1 0.03326 1 del_8p12 129 (49%) 135 9.9999e-06 0.007 0.00061999 0.388 0.55348 1 0.51585 1 0.13314 1 0.88512 1 0.03832 1 0.21944 1 0.12573 1 0.064179 1 del_8p11.21 69 (26%) 195 7.9999e-05 0.0518 0.44874 1 0.21338 1 0.24832 1 0.22791 1 0.27725 1 0.065399 1 0.39548 1 0.054629 1 0.054669 1 del_9p23 115 (44%) 149 9.9999e-06 0.007 0.3453 1 0.22029 1 0.20325 1 0.86586 1 0.04806 1 0.40232 1 0.66848 1 0.69368 1 0.69088 1 del_9p21.3 157 (59%) 107 9.9999e-06 0.007 0.86258 1 0.45214 1 0.0103 1 0.72564 1 0.074249 1 0.8843 1 0.93299 1 0.59336 1 0.83349 1 del_9q33.2 104 (39%) 160 9.9999e-06 0.007 0.03384 1 0.066709 1 0.00322 1 0.0129 1 0.00022 0.141 0.46358 1 0.099409 1 0.12906 1 0.02292 1 del_10p12.1 43 (16%) 221 0.95403 1 0.15515 1 0.89101 1 0.42982 1 0.01571 1 0.03671 1 0.36242 1 0.26441 1 0.36317 1 0.41835 1 del_10q23.31 106 (40%) 158 0.00251 1 0.01588 1 0.62752 1 0.59373 1 0.088239 1 0.63527 1 0.71269 1 0.10546 1 0.66979 1 0.38528 1 del_11p15.5 129 (49%) 135 9.9999e-06 0.007 0.00092999 0.574 0.36529 1 0.24309 1 0.02518 1 0.00061999 0.388 0.02986 1 0.10218 1 0.01518 1 0.11899 1 del_11q23.3 100 (38%) 164 9.9999e-06 0.007 0.12362 1 0.77519 1 0.83866 1 0.03203 1 0.084129 1 0.24156 1 0.80377 1 0.31591 1 0.62484 1 del_13q14.2 103 (39%) 161 4e-04 0.252 0.57544 1 0.0080299 1 0.00318 1 0.02373 1 0.4714 1 0.78218 1 0.0252 1 0.36551 1 0.6934 1 del_14q12 80 (30%) 184 9.9999e-06 0.007 0.00042 0.264 0.12074 1 0.070859 1 0.14436 1 0.0226 1 0.03991 1 0.02664 1 0.1166 1 0.35178 1 del_14q24.1 86 (33%) 178 9.9999e-06 0.007 9.9999e-06 0.007 0.39276 1 0.34597 1 0.00283 1 9.9999e-06 0.007 0.04636 1 0.00062999 0.393 0.084619 1 0.084149 1 del_15q13.1 107 (41%) 157 0.00026 0.166 0.00127 0.78 0.31931 1 0.5717 1 0.94665 1 0.56739 1 0.16178 1 5.9999e-05 0.0391 0.2816 1 0.16493 1 del_16p13.3 104 (39%) 160 0.00086999 0.539 0.01377 1 0.21255 1 0.46618 1 0.69438 1 0.91778 1 0.9467 1 0.03611 1 0.75934 1 0.83208 1 del_16q23.1 73 (28%) 191 5.9999e-05 0.0391 0.03422 1 0.50271 1 0.064299 1 0.088439 1 0.18246 1 0.03139 1 0.00031 0.196 0.1543 1 0.01403 1 del_17p12 137 (52%) 127 9.9999e-06 0.007 0.02255 1 0.20067 1 0.60918 1 0.37559 1 0.059869 1 0.75127 1 0.01031 1 0.86923 1 0.86368 1 del_18q21.2 115 (44%) 149 0.057109 1 0.87563 1 0.87183 1 0.74547 1 0.87651 1 0.67224 1 0.00457 1 0.00028 0.178 0.059639 1 0.03451 1 del_19p13.3 96 (36%) 168 0.00222 1 0.28082 1 0.85525 1 0.60751 1 0.0415 1 0.074339 1 0.45199 1 0.058459 1 0.17807 1 0.36037 1 del_22q13.31 118 (45%) 146 3e-05 0.0197 0.00178 1 0.45137 1 0.0077399 1 0.10204 1 0.46243 1 0.64462 1 0.10639 1 0.098099 1 0.49855 1 del_xp11.3 62 (23%) 202 0.0317 1 0.02897 1 0.73545 1 0.61682 1 0.20693 1 0.96226 1 0.094059 1 0.83756 1 0.29113 1 0.78545 1 del_xq21.33 53 (20%) 211 0.00276 1 0.01981 1 0.98031 1 0.4391 1 0.03412 1 0.23934 1 0.04933 1 0.37538 1 0.22526 1 0.056049 1 del_xq23 49 (19%) 215 0.065379 1 0.03048 1 0.99536 1 0.62269 1 0.33752 1 0.65451 1 0.22428 1 0.42372 1 0.17995 1 0.19647 1