Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.039 0.14 0.409 33.0 -9999.0 0.0 33.0 KIRREL -0.047 0.178 -9999.0 0.0 -0.577 27.0 27.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.039 0.141 -9999.0 0.0 -0.41 33.0 33.0 PLCG1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.046 0.11 -9999.0 0.0 -0.328 27.0 27.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.005 0.098 -9999.0 0.0 -0.293 17.0 17.0 FYN -0.027 0.118 -9999.0 0.0 -0.326 28.0 28.0 mol:Ca2+ -0.045 0.109 -9999.0 0.0 -0.326 27.0 27.0 mol:DAG -0.046 0.11 -9999.0 0.0 -0.327 27.0 27.0 NPHS2 -0.021 0.104 -9999.0 0.0 -0.491 12.0 12.0 mol:IP3 -0.046 0.11 -9999.0 0.0 -0.327 27.0 27.0 regulation of endocytosis -0.017 0.111 -9999.0 0.0 -0.36 12.0 12.0 Nephrin/NEPH1/podocin/Cholesterol -0.037 0.118 -9999.0 0.0 -0.299 42.0 42.0 establishment of cell polarity -0.039 0.14 -9999.0 0.0 -0.409 33.0 33.0 Nephrin/NEPH1/podocin/NCK1-2 -0.011 0.11 -9999.0 0.0 -0.431 5.0 5.0 Nephrin/NEPH1/beta Arrestin2 -0.016 0.113 -9999.0 0.0 -0.364 12.0 12.0 NPHS1 -0.011 0.073 -9999.0 0.0 -0.475 6.0 6.0 Nephrin/NEPH1/podocin -0.027 0.118 -9999.0 0.0 -0.327 28.0 28.0 TJP1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.046 0.11 -9999.0 0.0 -0.328 27.0 27.0 CD2AP 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.046 0.11 -9999.0 0.0 -0.328 27.0 27.0 GRB2 0.015 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.022 0.114 -9999.0 0.0 -0.311 27.0 27.0 cytoskeleton organization -0.004 0.114 -9999.0 0.0 -0.355 12.0 12.0 Nephrin/NEPH1 -0.025 0.1 -9999.0 0.0 -0.289 33.0 33.0 Nephrin/NEPH1/ZO-1 -0.04 0.105 -9999.0 0.0 -0.334 27.0 27.0