Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.123 0.228 -9999.0 0.0 -0.411 85.0 85.0 MAP3K8 0.006 0.062 -9999.0 0.0 -0.569 3.0 3.0 FOS -0.089 0.18 -9999.0 0.0 -0.454 34.0 34.0 PRKCA 0.009 0.036 -9999.0 0.0 -0.566 1.0 1.0 PTPN7 -0.004 0.094 -9999.0 0.0 -0.535 8.0 8.0 HRAS 0.014 0.002 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.151 0.262 -9999.0 0.0 -0.57 75.0 75.0 NRAS 0.014 0.002 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.021 0.023 -9999.0 0.0 -0.268 1.0 1.0 MAPK3 -0.047 0.126 -9999.0 0.0 -0.537 7.0 7.0 MAP2K1 -0.108 0.22 -9999.0 0.0 -0.447 75.0 75.0 ELK1 0.01 0.01 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.104 0.208 -9999.0 0.0 -0.431 75.0 75.0 mol:GTP -0.001 0.003 -9999.0 0.0 -0.005 80.0 80.0 MAPK1 -0.047 0.126 -9999.0 0.0 -0.537 7.0 7.0 RAF1 -0.105 0.208 -9999.0 0.0 -0.431 75.0 75.0 KRAS 0.012 0.031 -9999.0 0.0 -0.489 1.0 1.0