Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.039	0.22	0.43	4.0	-0.663	95.0	99.0
IHH	0.016	0.082	0.265	31.0	-0.204	69.0	100.0
SHH Np/Cholesterol/GAS1	0.001	0.075	-9999.0	0.0	-0.331	46.0	46.0
LRPAP1	0.024	0.005	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	-0.001	0.074	0.329	46.0	-9999.0	0.0	46.0
SMO/beta Arrestin2	-0.017	0.206	-9999.0	0.0	-0.616	92.0	92.0
SMO	-0.041	0.208	0.321	1.0	-0.649	92.0	93.0
AKT1	-0.003	0.128	-9999.0	0.0	-0.609	20.0	20.0
ARRB2	0.022	0.007	-9999.0	0.0	-9999.0	0.0	0.0
BOC	-0.018	0.153	-9999.0	0.0	-0.57	74.0	74.0
ADRBK1	0.023	0.006	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.04	0.204	0.32	1.0	-0.637	92.0	93.0
STIL	0.008	0.172	0.3	28.0	-0.481	81.0	109.0
DHH N/PTCH2	-0.011	0.144	-9999.0	0.0	-0.443	100.0	100.0
DHH N/PTCH1	-0.026	0.203	-9999.0	0.0	-0.55	114.0	114.0
PIK3CA	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.008	0.099	0.257	2.0	-0.57	29.0	31.0
PTHLH	-0.059	0.295	0.519	2.0	-0.881	99.0	101.0
determination of left/right symmetry	-0.04	0.204	0.32	1.0	-0.637	92.0	93.0
PIK3R1	0.018	0.055	-9999.0	0.0	-0.57	9.0	9.0
skeletal system development	-0.058	0.29	0.518	2.0	-0.863	100.0	102.0
IHH N/Hhip	0.027	0.057	0.236	2.0	-0.462	2.0	4.0
DHH N/Hhip	0.022	0.079	-9999.0	0.0	-0.418	31.0	31.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.04	0.204	0.32	1.0	-0.637	92.0	93.0
pancreas development	0.023	0.032	0.256	6.0	-0.57	2.0	8.0
HHAT	0.02	0.021	-9999.0	0.0	-0.57	1.0	1.0
PI3K	0.03	0.042	-9999.0	0.0	-0.397	9.0	9.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.007	0.132	-9999.0	0.0	-0.57	54.0	54.0
somite specification	-0.04	0.204	0.32	1.0	-0.637	92.0	93.0
SHH Np/Cholesterol/PTCH1	-0.023	0.158	0.298	1.0	-0.498	85.0	86.0
SHH Np/Cholesterol/PTCH2	-0.005	0.086	-9999.0	0.0	-0.332	61.0	61.0
SHH Np/Cholesterol/Megalin	-0.059	0.148	0.204	9.0	-0.303	259.0	268.0
SHH	-0.0	0.038	0.342	7.0	-0.426	1.0	8.0
catabolic process	-0.031	0.204	0.33	1.0	-0.61	100.0	101.0
SMO/Vitamin D3	-0.008	0.196	0.365	14.0	-0.567	86.0	100.0
SHH Np/Cholesterol/Hhip	0.015	0.031	0.283	4.0	-0.336	3.0	7.0
LRP2	-0.121	0.264	0.257	25.0	-0.57	264.0	289.0
receptor-mediated endocytosis	-0.078	0.219	0.308	7.0	-0.622	97.0	104.0
SHH Np/Cholesterol/BOC	-0.004	0.085	-9999.0	0.0	-0.332	60.0	60.0
SHH Np/Cholesterol/CDO	0.012	0.042	-9999.0	0.0	-0.333	13.0	13.0
mesenchymal cell differentiation	-0.015	0.03	0.334	3.0	-0.281	4.0	7.0
mol:Vitamin D3	0.004	0.179	0.348	19.0	-0.505	83.0	102.0
IHH N/PTCH2	-0.008	0.141	-9999.0	0.0	-0.466	80.0	80.0
CDON	0.014	0.066	-9999.0	0.0	-0.57	13.0	13.0
IHH N/PTCH1	-0.022	0.21	0.352	4.0	-0.573	116.0	120.0
Megalin/LRPAP1	-0.078	0.202	0.196	22.0	-0.416	269.0	291.0
PTCH2	-0.021	0.157	-9999.0	0.0	-0.57	78.0	78.0
SHH Np/Cholesterol	0.01	0.013	-9999.0	0.0	-0.332	1.0	1.0
PTCH1	-0.031	0.205	0.33	1.0	-0.613	100.0	101.0
HHIP	0.023	0.032	0.257	6.0	-0.57	2.0	8.0