Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.095 0.197 0.633 113.0 -9999.0 0.0 113.0 KIRREL -0.079 0.25 -9999.0 0.0 -0.801 113.0 113.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.095 0.198 -9999.0 0.0 -0.635 113.0 113.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.069 0.15 -9999.0 0.0 -0.485 113.0 113.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.042 0.111 -9999.0 0.0 -0.361 113.0 113.0 FYN -0.064 0.144 -9999.0 0.0 -0.464 113.0 113.0 mol:Ca2+ -0.068 0.148 -9999.0 0.0 -0.48 113.0 113.0 mol:DAG -0.068 0.149 -9999.0 0.0 -0.482 113.0 113.0 NPHS2 -0.008 0.03 -9999.0 0.0 -0.291 4.0 4.0 mol:IP3 -0.068 0.149 -9999.0 0.0 -0.482 113.0 113.0 regulation of endocytosis -0.054 0.136 -9999.0 0.0 -0.432 113.0 113.0 Nephrin/NEPH1/podocin/Cholesterol -0.071 0.153 -9999.0 0.0 -0.493 113.0 113.0 establishment of cell polarity -0.095 0.197 -9999.0 0.0 -0.633 113.0 113.0 Nephrin/NEPH1/podocin/NCK1-2 -0.061 0.136 -9999.0 0.0 -0.441 113.0 113.0 Nephrin/NEPH1/beta Arrestin2 -0.055 0.138 -9999.0 0.0 -0.438 113.0 113.0 NPHS1 -0.047 0.111 -9999.0 0.0 -0.293 175.0 175.0 Nephrin/NEPH1/podocin -0.064 0.145 -9999.0 0.0 -0.466 113.0 113.0 TJP1 -0.001 0.024 -9999.0 0.0 -0.795 1.0 1.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.069 0.15 -9999.0 0.0 -0.485 113.0 113.0 CD2AP -0.0 0.009 -9999.0 0.0 -0.292 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 -0.069 0.15 -9999.0 0.0 -0.485 113.0 113.0 GRB2 -0.0 0.009 -9999.0 0.0 -0.292 1.0 1.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.069 0.169 -9999.0 0.0 -0.504 121.0 121.0 cytoskeleton organization -0.053 0.138 -9999.0 0.0 -0.45 113.0 113.0 Nephrin/NEPH1 -0.069 0.148 -9999.0 0.0 -0.476 113.0 113.0 Nephrin/NEPH1/ZO-1 -0.075 0.163 -9999.0 0.0 -0.524 113.0 113.0